EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

potassium bromate
bromic acid, potassium salt (1:1)

Supplier Sponsors

CAS Number: 7758-01-2Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:231-829-8
FDA UNII:04MB35W6ZA
Nikkaji Web:J43.934G
MDL:MFCD00011359
Molecular Weight:166.99990000
Formula:Br K O3
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome or firefox)
Category:malting of barley
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
FDA Mainterm (SATF):7758-01-2 ; POTASSIUM BROMATE
FDA Regulation:
FDA PART 136 -- BAKERY PRODUCTS
Subpart B--Requirements for Specific Standardized Bakery Products
Sec. 136.110 Bread, rolls, and buns.


FDA PART 136 -- BAKERY PRODUCTS
Subpart B--Requirements for Specific Standardized Bakery Products
Sec. 136.180 Whole wheat bread, rolls, and buns.


FDA PART 137 -- CEREAL FLOURS AND RELATED PRODUCTS
Subpart B--Requirements for Specific Standardized Cereal Flours and Related Products
Sec. 137.155 Bromated flour.


FDA PART 137 -- CEREAL FLOURS AND RELATED PRODUCTS
Subpart B--Requirements for Specific Standardized Cereal Flours and Related Products
Sec. 137.160 Enriched bromated flour.


FDA PART 137 -- CEREAL FLOURS AND RELATED PRODUCTS
Subpart B--Requirements for Specific Standardized Cereal Flours and Related Products
Sec. 137.205 Bromated whole wheat flour.


FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION
Subpart H--Other Specific Usage Additives
Sec. 172.730 Potassium bromate.
 
Physical Properties:
Food Chemicals Codex Listed: No
Soluble in:
 water, 1e+006 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses:
 
Suppliers:
American Elements
Potassium Bromate 99%
Odor: characteristic
Use: Potassium Bromate is generally immediately available in most volumes. High purity, submicron and nanopowder forms may be considered. American Elements produces to many standard grades when applicable, including Mil Spec (military grade); ACS, Reagent and Technical Grade; Food, Agricultural and Pharmaceutical Grade; Optical Grade, USP and EP/BP (European Pharmacopoeia/British Pharmacopoeia) and follows applicable ASTM testing standards.
American International Chemical, LLC.
Potassium Bromate
Penta International
POTASSIUM BROMATE
Sigma-Aldrich
For experimental / research use only.
Potassium Bromate ReagentPlus®, ≥99%
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50 157 mg/kg
GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION
Eisei Kagaku. Hygienic Chemistry. Vol. 37, Pg. 258, 1991.

oral-child TDLo 7125 uL/kg
GASTROINTESTINAL: NAUSEA OR VOMITING LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)
British Medical Journal. Vol. 1, Pg. 1363, 1951.

oral-hamster LD50 388 mg/kg
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)
EHP, Environmental Health Perspectives. Vol. 87, Pg. 309, 1990.

oral-human TDLo 714 mg/kg
SENSE ORGANS AND SPECIAL SENSES: CHANGE IN ACUITY: EAR GASTROINTESTINAL: NAUSEA OR VOMITING KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)"
Nephron. Vol. 37, Pg. 278, 1984.

intraperitoneal-mouse LD50 177 mg/kg
Mutation Research. Vol. 223, Pg. 399, 1989.

oral-mouse LD50 289 mg/kg
Mutation Research. Vol. 223, Pg. 399, 1989.

intraperitoneal-rat LD50 50 mg/kg
Journal of the American College of Toxicology. Vol. 13, Pg. 400, 1994.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category: malting of barley
Recommendation for potassium bromate usage levels up to:
 not for fragrance use.
 
Recommendation for potassium bromate flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
NIOSH International Chemical Safety Cards:search
NLM Hazardous Substances Data Bank:Search
Chemical Carcinogenesis Research Information System:Search
Cancer Citations:Search
Toxicology Citations:Search
Carcinogenic Potency Database:Search
EPA GENetic TOXicology:Search
Env. Mutagen Info. Center:Search
NLM Developmental and Reproductive Toxicity:Search
EPA Substance Registry Services (TSCA):7758-01-2
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :23673461
National Institute of Allergy and Infectious Diseases:Data
SCCNFP:opinion
WGK Germany:3
potassium bromate
Chemidplus:0007758012
EPA/NOAA CAMEO:hazardous materials
RTECS:7758-01-2
 
References:
 potassium bromate
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):23673461
Pubchem (sid):134989983
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2009
(IUPAC):Atomic Weights of the Elements 2009 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):View
CHEBI:View
CHEMBL:View
KEGG (GenomeNet):C19295
HMDB (The Human Metabolome Database):Search
FooDB:FDB015414
Export Tariff Code:2829.90.1000
FDA Listing of Food Additive Status:View
Haz-Map:View
ChemSpider:View
Wikipedia:View
RSC Learn Chemistry:View
Formulations/Preparations:
•pure (not less than 99.5%) and reagent (not less than 99.8%). •grades: pure; cp; fcc •permanent hair wave neutralizing solutions usually contain either 2% potassium bromate or 10% sodium bromate.
 
Potential Blenders and core components note
None Found
 
Potential Uses:
 oxidising agents
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 bromate-21
 bromate-50
 bromate, potassium
 bromic acid potassium salt (1:1)
 bromic acid, potassium salt
 bromic acid, potassium salt (1:1)
 potassium bromate powder FCC
 

Articles:

PubMed:Protective effect of taurine against potassium bromate-induced hemoglobin oxidation, oxidative stress, and impairment of antioxidant defense system in blood.
PubMed:Evaluation of repeated dose micronucleus assays of the liver and gastrointestinal tract using potassium bromate: A report of the collaborative study by CSGMT/JEMS.MMS.
PubMed:The catalytic kinetic method for the determination of trace formaldehyde (FA) base on a bromate-eosin Y system.
PubMed:A sensitive colorimetric method for the determination of nitrite in water supplies, meat and dairy products using ionic liquid-modified methyl red as a colour reagent.
PubMed:A new catalytic oxidation method for sensitive quantification of bromate in flours and bottled water using AgNPs.
PubMed:Taurine ameliorates potassium bromate-induced kidney damage in rats.
PubMed:DNA damage and DNA-protein cross-linking induced in rat intestine by the water disinfection by-product potassium bromate.
PubMed:Oral administration of a nephrotoxic dose of potassium bromate, a food additive, alters renal redox and metabolic status and inhibits brush border membrane enzymes in rats.
PubMed:Oxidative stress induced by potassium bromate exposure results in altered tight junction protein expression in renal proximal tubule cells.
PubMed:Oral administration of potassium bromate, a major water disinfection by-product, induces oxidative stress and impairs the antioxidant power of rat blood.
PubMed:Supplementation of Nigella sativa fixed and essential oil mediates potassium bromate induced oxidative stress and multiple organ toxicity.
PubMed:Determination of acrylamide in starch-based foods by HPLC with pre-column ultraviolet derivatization.
PubMed:Potassium bromate causes cell lysis and induces oxidative stress in human erythrocytes.
PubMed:[Quantification of acrylamide in foods by gas chromatography-mass spectrometry coupled with pro-column derivatization].
PubMed:Possible involvement of oxidative stress in potassium bromate-induced genotoxicity in human HepG2 cells.
PubMed:Impact of potassium bromate and potassium iodate in a pound cake system.
PubMed:The effect of potassium bromate on some haematological parameters of Wistar rats.
PubMed:Flow injection kinetic spectrophotometric method for the determination of trace amounts of nitrite.
PubMed:Potassium bromate content of selected bread samples in Ilorin, Central Nigeria and its effect on some enzymes of rat liver and kidney.
PubMed:Early alterations in protein and gene expression in rat kidney following bromate exposure.
PubMed:[Relationship between toxic effects of potassium bromate and endocrine glands].
PubMed:Kinetic-spectrophotometric determination of trace amounts of vanadium.
PubMed:A pilot study of evaluation of the antioxidative activity of resveratrol and its analogue in a 6-month feeding test in young adult mice.
PubMed:Protective effects of bilberry (Vaccinium myrtillus L.) extract on KBrO3-induced kidney damage in mice.
PubMed:Impact of redox agents on the extractability of gluten proteins during bread making.
PubMed:Kinetic spectrophotometric method for rapid determination of trace formaldehyde in foods.
PubMed:Determination of acrylamide in Chinese traditional carbohydrate-rich foods using gas chromatography with micro-electron capture detector and isotope dilution liquid chromatography combined with electrospray ionization tandem mass spectrometry.
PubMed:Rapid determination of acrylamide contaminant in conventional fried foods by gas chromatography with electron capture detector.
PubMed:Multiple outbreaks of gastrointestinal illness among school children associated with consumption of flour tortillas--Massachusetts, 2003-2004.
PubMed:Kidney toxicogenomics of chronic potassium bromate exposure in f344 male rats.
PubMed:Quantitation of dityrosine in wheat flour and dough by liquid chromatography-tandem mass spectrometry.
PubMed:Simultaneous spectrophotometric determination of nitrite and nitrate by flow injection analysis.
PubMed:Lack of genotoxicity of potassium iodate in the alkaline comet assay and in the cytokinesis-block micronucleus test. Comparison to potassium bromate.
PubMed:Characterization of sulfur speciation in low molecular weight subunits of glutenin after reoxidation with potassium iodate and potassium bromate at different pH values using x-ray absorption near-edge structure (XANES) spectroscopy.
PubMed:Determination of acrylamide in foods by GC/MS using 13C-labeled acrylamide as an internal standard.
PubMed:Toxic bromate residues in Nigerian bread.
PubMed:Effect of raw wheat germ addition on the physical texture and objective color of a designer food (pan bread).
PubMed:Requirement of glutathione and cysteine in guanine-specific oxidation of DNA by carcinogenic potassium bromate.
PubMed:The detrimental effects of potassium bromate and thioglycolate on auditory brainstem response of guinea pigs.
PubMed:Potassium bromate.
PubMed:Measurement of bromate in bread by liquid chromatography with post-column flow reactor detection.
PubMed:Hydroquinone: genotoxicity and prevention of genotoxicity following ingestion.
PubMed:Time- and dose-dependent development of potassium bromate-induced tumors in male Fischer 344 rats.
PubMed:DNA oxidation by potassium bromate; a direct mechanism or linked to lipid peroxidation?
PubMed:Enhancement of ethylenethiourea recoveries in food analyses by addition of cysteine hydrochloride.
PubMed:Evaluation of certain food additives and contaminants.
PubMed:The determination of the flour improver potassium bromate in bread by gas chromatographic and ICP-MS methods.
PubMed:Practical applications of element-specific detection by inductively coupled plasma atomic emission spectroscopy and inductively coupled plasma mass spectrometry to ion chromatography of foods.
PubMed:[Substitution of ascorbic acid for potassium bromide in the making of French bread].
PubMed:A possible role for cell proliferation in potassium bromate (KBrO3) carcinogenesis.
PubMed:Effects of antioxidants on induction of micronuclei in rat peripheral blood reticulocytes by potassium bromate.
PubMed:Lack of renal tumour-initiating activity of a single dose of potassium bromate, a genotoxic renal carcinogen in male F344/NCr rats.
PubMed:Generation of active oxygen species in vitro by the interaction of potassium bromate with rat kidney cell.
PubMed:Relation of 8-hydroxydeoxyguanosine formation in rat kidney to lipid peroxidation, glutathione level and relative organ weight after a single administration of potassium bromate.
PubMed:Toxicity and carcinogenicity of potassium bromate--a new renal carcinogen.
PubMed:Regulation of food-related carcinogens in Japan.
PubMed:Mutagens and carcinogens in the diet. Regulatory perspective: Japan.
PubMed:Micronucleus tests in mice on 39 food additives and eight miscellaneous chemicals.
PubMed:Dose-response studies on the carcinogenicity of potassium bromate in F344 rats after long-term oral administration.
PubMed:Potassium bromate.
PubMed:Dose-related enhancing effect of potassium bromate on renal tumorigenesis in rats initiated with N-ethyl-N-hydroxyethyl-nitrosamine.
PubMed:Risk evaluation of tumor-inducing substances in foods.
PubMed:Primary mutagenicity screening of food additives currently used in Japan.
PubMed:Carcinogenicity of potassium bromate administered orally to F344 rats.
PubMed:Enhancement by potassium bromate of renal tumorigenesis initiated by N-ethyl-N-hydroxyethylnitrosamine in F-344 rats.
PubMed:Induction of renal cell tumors in F-344 rats by oral administration of potassium bromate, a food additive.
PubMed:[Carcinogenicity of potassium bromate in F-344 rats].
PubMed:New considerations on hydrogen peroxide and related substances as food additives in view of carcinogenicity.
PubMed:Improved 4-aminoantipyrine colorimetry for detection of residual hydrogen peroxide in noodles, fish paste, dried fish, and herring roe.
PubMed:Long-term toxicity and carcinogenicity studies of the bread improver potassium bromate 2. Studies in mice.
PubMed:Long-term toxicity and carcinogenicity studies of the bread improver potassium bromate 1. Studies in rats.
PubMed:The fate of potassium bromate when used as a breadmaking improver.
PubMed:Cysteinimetry. Determination of the potassium bromate content of buffalo milk.
PubMed:An outbreak of food-poisoning due to a flour improver, potassium bromate.
PubMed:Chemical food poisoning by potassium bromate. Report of an outbreak.
 
Notes:
used as bread improver. Dough conditioning agent used in bread making. Normally decomposed during the baking process; also used in barley malting
Please share your Comments.
Email Address:
Top of Page Home
Copyright © 1980-2018 The Good Scents Company (tgsc) ™ Disclaimer Privacy Policy