EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

dextro-leucine
D-2-amino-4-methylpentanoic acid

Supplier Sponsors

CAS Number: 328-38-1Picture of molecule3D/inchi
Other(deleted CASRN):1606170-98-2
ECHA EINECS - REACH Pre-Reg:206-327-7
FDA UNII: 965COD96YA
Nikkaji Web:J1.285H
Beilstein Number:1721721
MDL:MFCD00063088
XlogP3:-1.50 (est)
Molecular Weight:131.17501000
Formula:C6 H13 N O2
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:information only not used for fragrances or flavors
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 302.00 °C. @ 760.00 mm Hg
Boiling Point: 225.77 °C. @ 760.00 mm Hg (est)
Vapor Pressure:0.031000 mmHg @ 25.00 °C. (est)
Flash Point: 195.00 °F. TCC ( 90.30 °C. ) (est)
logP (o/w): 0.799 (est)
Soluble in:
 water, 1.538e+004 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BOC Sciences
For experimental / research use only.
D-homo-Valine >98.0%(T)
Changzhou Longo Chemical
D-Leucine
Glentham Life Sciences
D-Leucine
Penta International
D-LEUCINE
Santa Cruz Biotechnology
For experimental / research use only.
L-Leucine-1-13C
Sigma-Aldrich: Aldrich
For experimental / research use only.
D-Leucine ReagentPlus®, 99%
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intraperitoneal-rat LD50 6429 mg/kg
BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Archives of Biochemistry and Biophysics. Vol. 64, Pg. 319, 1956.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
information only not used for fragrances or flavors
Recommendation for dextro-leucine usage levels up to:
 not for fragrance use.
 
Recommendation for dextro-leucine flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):328-38-1
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :857
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
(2R)-2-amino-4-methylpentanoic acid
Chemidplus:0000328381
RTECS:OH2840000 for cas# 328-38-1
 
References:
 (2R)-2-amino-4-methylpentanoic acid
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):857
Pubchem (sid):134973452
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
CHEMBL:View
Golm Metabolome Database:Search
KEGG (GenomeNet):C01570
HMDB (The Human Metabolome Database):HMDB13773
YMDB (Yeast Metabolome Database):YMDB00997
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
 antistatic agents
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
(R)-2-amino-4-methyl-pentanoic acid
(2R)-2-amino-4-methylpentanoic acid
(R)-2-amino-4-methylpentanoic acid
D-2-amino-4-methylpentanoic acid
D-2-amino-4-methylpentanoicacid
D-2-amino-4-methylvaleric acid
D-leucin
(R)-leucine
(R)-(-)-leucine
D-leucine
 leucine, D-
D-leuzin
 

Articles:

PubMed:Convergent evolution of [D-Leucine(1)] microcystin-LR in taxonomically disparate cyanobacteria.
PubMed:Prolonged leucine supplementation does not augment muscle mass or affect glycemic control in elderly type 2 diabetic men.
PubMed:D-amino acid formation in sterilized alkali-treated olives.
PubMed:Suppression of myofibrillar proteolysis in chick skeletal muscles by alpha-ketoisocaproate.
PubMed:A new strategy for the selective determination of D-amino acids: enzymatic and chemical modifications for pre-column derivatization.
PubMed:Tissue-specific regulation of 4E-BP1 and S6K1 phosphorylation by alpha-ketoisocaproate.
PubMed:Feeding, drinking, urine osmolality in DI Brattleboro rats: changes by morphine, naloxone, D-amino acids, prolyl-leucyl-glycinamide (PLG).
PubMed:Peptidase activity in Tetrahymena.
 
Notes:
None found
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