EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

ellagic acid
4,4',5,5',6,6'-hexahydroxydiphenic acid 2,6,2',6'-dilactone

Supplier Sponsors

CAS Number: 476-66-4Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:207-508-3
FDA UNII: 19YRN3ZS9P
Nikkaji Web:J5.977C
Beilstein Number:0047549
MDL:MFCD00006914
XlogP3-AA:1.10 (est)
Molecular Weight:302.19542000
Formula:C14 H6 O8
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:cosmetic agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
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Google Patents:Search
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PubMed:Search
NCBI:Search
 
Physical Properties:
Appearance:cream needles or powder (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 360.00 to 364.00 °C. @ 760.00 mm Hg
Boiling Point: 796.50 °C. @ 760.00 mm Hg (est)
Vapor Pressure:2.810000 mmHg @ 25.00 °C. (est)
Flash Point: 590.00 °F. TCC ( 310.10 °C. ) (est)
logP (o/w): 0.239 (est)
Soluble in:
 water, 7.828e+004 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses:
 
Suppliers:
Alfa Biotechnology
For experimental / research use only.
Ellagic acid 98%
BOC Sciences
For experimental / research use only.
Ellagic acid >98%
Odor: characteristic
Use: Ellagic acid is a natural phenol antioxidant found in numerous fruits and vegetables. The antiproliferative and antioxidant properties of ellagic acid have prompted research into its potential health benefits.
Changsha Organic Herb
Pomegranate Extract Ellagic acid
Changsha Organic Herb
Pomegranate Extract Punicalagin A + B Ellagic Acid
Changzhou Longo Chemical
Ellagic Acid
Coompo
For experimental / research use only.
Ellagic Acid from Plants ≥96%
Odor: characteristic
Use: Astringent (intestinal), haemostatic, antioxidant, antineoplastic and antimutagenic agent. Dietary role in vivo disputed. Ellagic acid were evaluated for antiproliferative activity at 12.5–100 µg/ml on human oral (KB, CAL27), colon (HT-29, HCT116, SW480, SW620) and prostate (RWPE-1, 22Rv1) tumor cells. Ellagic acid is a potent antagonist of the adverse biological effects of the ultimate carcinogenic metabolites of several polycyclic aromatic hydrocarbons and suggest that this naturally occurring plant phenol, normally ingested by humans, may inhibit the carcinogenicity of polycyclic aromatic hydrocarbons.
EMD Millipore
For experimental / research use only.
Ellagic Acid, Dihydrate
ExtraSynthese
For experimental / research use only.
Ellagic Acid (HPLC) ≥90%
Glentham Life Sciences
Ellagic acid
Jiangyin Healthway
Ellagic Acid
New functional food ingredients
Jiangyin Healthway
Ellagic Acid
M.C.Biotec
Ellagic Acid
Odor: characteristic
Use: anti-wrinkle and antioxidant
Minasolve
MinaCare Elage ECOCERT(Ellagic Acid)
Odor: characteristic
Use: MinaCare Elage ECOCERT is a well known whitening agent. It inhibits the enzyme thyrosinase, which is part of the melanin production cascade. This active ingredient is a nature identical molecule, occurring in pomegranates and berries. However its extraction does not allow reaching a sufficient assay to formulate it in cosmetics. Consequently Minasolve developed an ECOCERT process that provides a min. 98% quality to solve cosmetics formulation issues.
NewChem Technologies
For experimental / research use only.
Ellagic Acid
O'Laughlin Industries
Ellagic Acid (Strawberry Extract)
Penta International
ELLAGIC ACID
Sabinsa Corporation
Ellagic Acid
Santa Cruz Biotechnology
For experimental / research use only.
Ellagic Acid, Dihydrate ≥96%
Shaanxi Y-Herb Biotechnology
China Pomegranate Peel Extract Ellagic Acid Powder Pure Bark Polyphenol Gallogen
Shaanxi Y-Herb Biotechnology
Organic Pomegranate Extract Powder Punicalagin 40% Ellagic Acid For Skin Whitening
Sigma-Aldrich
For experimental / research use only.
Ellagic Acid
analytical standard
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD > 20000 mg/kg
Farmatsevtichnii Zhurnal Vol. 54(6), Pg. 90, 1999.

intraperitoneal-rat LDLo 630 mg/kg
BEHAVIORAL: FOOD INTAKE (ANIMAL) BEHAVIORAL: ATAXIA BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Farmatsevtichnii Zhurnal Vol. 54(6), Pg. 90, 1999.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
cosmetic agents
Recommendation for ellagic acid usage levels up to:
 not for fragrance use.
 
Recommendation for ellagic acid flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
ClinicalTrials.gov:search
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :5281855
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:1
2,3,7,8-tetrahydroxychromeno[5,4,3-cde]chromene-5,10-dione
Chemidplus:0000476664
EPA/NOAA CAMEO:hazardous materials
RTECS:DJ2620000 for cas# 476-66-4
 
References:
 2,3,7,8-tetrahydroxychromeno[5,4,3-cde]chromene-5,10-dione
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):5281855
Pubchem (sid):134973503
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
CHEMBL:View
KEGG (GenomeNet):C10788
HMDB (The Human Metabolome Database):HMDB02899
FooDB:FDB012575
YMDB (Yeast Metabolome Database):YMDB01679
MedlinePlusSupp:View
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 blueberry plant
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 brazil nut
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 brazil nut bark
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 chestnut sweet chestnut leaf
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 clove bark
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 clove bud
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 clove fruit
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 evening-primrose leaf
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 grape fruit
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 guava bark
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 guava flower
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 guava fruit
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 guava leaf
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 guava pericarp
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 guava stem bark
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 guava strawberry guava plant
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 guva flower
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 jambul
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 myrob nuts
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 pomegranate flower
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 pomegranate fruit
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 pomegranate leaf
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 pomegranate pericarp
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 pomegranate seed
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 pomegranate stem bark
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 raspberry red raspberry
Search Trop Picture
 raspberry red raspberry fruit
Search Trop Picture
 raspberry red raspberry juice
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 raspberry red raspberry leaf
Search Trop Picture
 sage plant
Search Trop Picture
 walnut black walnut fruit
Search Trop Picture
 walnut black walnut nut
Search Trop Picture
 walnut black walnut pericarp
Search Trop Picture
 walnut black walnut shoot
Search Trop Picture
 walnut english walnut fruit
Search Trop Picture
 walnut english walnut nut
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 walnut english walnut testa
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Synonyms:
 acid, benzoaric
 acid, ellagic
 alizarin yellow
 alizarine yellow
 benzoaric acid
 diphenic acid, 4,4',5,5',6,6'-hexahydroxy-, di-d-lactone
 eleagic acid
 ellagicacid
 gallogen
4,4',5,5',6,6'-hexahydrodiphenic acid 2,6,2',6'-dilactone
4,4',5,5',6,6'-hexahydroxydiphenic acid 2,6,2',6'-dilactone
 lagistase
 llagic acid
 pomegranate extract ellagic acid
 pomegranate extract punicalagin A + B ellagic acid
2,3,7,8-tetrahydroxy-[1]benzopyrano[5,4,3-cde][1]benzopyran-5,10-dione
2,3,7,8-tetrahydroxy-chromeno[5,4,3-cde]chromene-5,10-dione
2,3,7,8-tetrahydroxy(1)benzopyrano(5,4,3-cde)-(1)benzopyran-5,10-dione
2,3,7,8-tetrahydroxy[1]benzopyrano-[5,4,3-cde][1]benzopyran-5,10-dione
2,3,7,8-tetrahydroxy[1]benzopyrano[5,4,3-cde][1]benzopyran-5,10-dione
2,3,7,8-tetrahydroxychromeno[5,4,3-cde]chromene-5,10-dione
 

Articles:

PubMed:Phytonutrient intakes in relation to European fruit and vegetable consumption patterns observed in different food surveys.
PubMed:Allelochemicals in the Rhizosphere Soil of Euphorbia himalayensis.
PubMed:Optimization of Ellagitannase Production by Aspergillus Niger GH1 by Solid State Fermentation.
PubMed:Psidium cattleianum fruit extracts are efficient in vitro scavengers of physiologically relevant reactive oxygen and nitrogen species.
PubMed:Inhibition of allergic airway inflammation through the blockage of NF-κB activation by ellagic acid in an ovalbumin-induced mouse asthma model.
PubMed:Ellagic Acid metabolism by human gut microbiota: consistent observation of three urolithin phenotypes in intervention trials, independent of food source, age, and health status.
PubMed:Ellagic Acid Modulates LPS-Induced Maturation of Dendritic Cells Through the Regulation of JNK Activity.
PubMed:An anthocyanin-rich strawberry extract protects against oxidative stress damage and improves mitochondrial functionality in human dermal fibroblasts exposed to an oxidizing agent.
PubMed:Antioxidant Activity and Protein-Polyphenol Interactions in a Pomegranate (Punica granatum L.) Yogurt.
PubMed:Ellagic acid inhibits adipocyte differentiation through coactivator-associated arginine methyltransferase 1-mediated chromatin modification.
PubMed:Description of urolithin production capacity from ellagic acid of two human intestinal Gordonibacter species.
PubMed:The structure, occurrence and biological activity of ellagitannins: a general review.
PubMed:Cecal Succinate Elevated by Some Dietary Polyphenols May Inhibit Colon Cancer Cell Proliferation and Angiogenesis.
PubMed:Spectroscopic studies on the antioxidant activity of ellagic acid.
PubMed:Quality and chemical composition of ten red raspberry (Rubus idaeus L.) genotypes during three harvest seasons.
PubMed:Gordonibacter urolithinfaciens sp. nov., a urolithin-producing bacterium isolated from the human gut.
PubMed:Separation and Characterization of Phenolic Compounds from U.S. Pecans by Liquid Chromatography-Tandem Mass Spectrometry.
PubMed:Effects of raspberry fruit extracts and ellagic acid on respiratory burst in murine macrophages.
PubMed:Tannin analysis of chestnut bark samples (Castanea sativa Mill.) by HPLC-DAD-MS.
PubMed:NOVEL TRENDS FOR USE OF MICROBIAL TANNASES.
PubMed:Metabolic fate of ellagitannins: implications for health, and research perspectives for innovative functional foods.
PubMed:Anti-diabetic effects of the Indian indigenous fruit Emblica officinalis Gaertn: active constituents and modes of action.
PubMed:Antimicrobial activities of various fractions of longan (Dimocarpus longan Lour. Fen Ke) seed extract.
PubMed:Targeted metabolic profiling of pomegranate polyphenols and urolithins in plasma, urine and colon tissues from colorectal cancer patients.
PubMed:NMR-based metabolomic investigation of bioactivity of chemical constituents in black raspberry (Rubus occidentalis L.) fruit extracts.
PubMed:Effect of frozen storage on the anthocyanins and phenolic components of pomegranate juice.
PubMed:Active compounds and medicinal properties of Myrciaria genus.
PubMed:Activity-guided isolation of antioxidants from the leaves of Terminalia arjuna.
PubMed:Tannin-rich fraction from pomegranate rind damages membrane of Listeria monocytogenes.
PubMed:Comprehensive identification of walnut polyphenols by liquid chromatography coupled to linear ion trap-Orbitrap mass spectrometry.
PubMed:Inhibition of nonenzymatic protein glycation by pomegranate and other fruit juices.
PubMed:Feijoa sellowiana Berg fruit juice: anti-inflammatory effect and activity on superoxide anion generation.
PubMed:Phytochemical divergence in 45 accessions of Terminalia ferdinandiana (Kakadu plum).
PubMed:Molecular approaches toward targeted cancer prevention with some food plants and their products: inflammatory and other signal pathways.
PubMed:Absorption, Metabolism, and Effects at Transcriptome Level of a Standardized French Oak Wood Extract, Robuvit, in Healthy Volunteers: Pilot Study.
PubMed:Strawberry as a functional food: an evidence-based review.
PubMed:The anti-inflammatory effect of a pomegranate husk extract on inflamed adipocytes and macrophages cultivated independently, but not on the inflammatory vicious cycle between adipocytes and macrophages.
PubMed:An aqueous pomegranate seed extract ameliorates oxidative stress of human hepatoma HepG2 cells.
PubMed:Nonanthocyanin secondary metabolites of black raspberry (Rubus occidentalis L.) fruits: identification by HPLC-DAD, NMR, HPLC-ESI-MS, and ESI-MS/MS analyses.
PubMed:Seasonal variation of the main individual phenolics and juglone in walnut (Juglans regia) leaves.
PubMed:Chemical guide parameters for Punica granatum cv. 'Mollar' fruit juices processed at industrial scale.
PubMed:Phenolic profile, antioxidant potential and DNA damage protecting activity of sugarcane (Saccharum officinarum).
PubMed:Evaluation of in vitro antioxidant and in vivo analgesic potential of Terminalia paniculata aqueous bark extract.
PubMed:Ellagic Acid Identified through Metabolomic Analysis Is an Active Metabolite in Strawberry ('Seolhyang') Regulating Lipopolysaccharide-Induced Inflammation.
PubMed:Profiling polyphenols of two diploid strawberry (Fragaria vesca) inbred lines using UHPLC-HRMS(n.).
PubMed:Polyphenols in Barringtonia racemosa and their protection against oxidation of LDL, serum and haemoglobin.
PubMed:Phenolic profile and antioxidant activity of Serbian polyfloral honeys.
PubMed:Isolation by pressurised fluid extraction (PFE) and identification using CPC and HPLC/ESI/MS of phenolic compounds from Brazilian cherry seeds (Eugenia uniflora L.).
PubMed:Assessment of pomegranate wine lees as a valuable source for the recovery of (poly)phenolic compounds.
PubMed:Urolithins display both antioxidant and pro-oxidant activities depending on assay system and conditions.
PubMed:Ellagic acid induces a dose- and time-dependent depolarization of mitochondria and activation of caspase-9 and -3 in human neuroblastoma cells.
PubMed:Density functional predictions of antioxidant activity and UV spectral features of nasutin A, isonasutin, ellagic acid, and one of its possible derivatives.
PubMed:Evolution of ellagitannin content and profile during fruit ripening in Fragaria spp.
PubMed:Time course production of urolithins from ellagic acid by human gut microbiota.
PubMed:HPLC Evaluation of Phenolic Profile, Nutritive Content, and Antioxidant Capacity of Extracts Obtained from Punica granatum Fruit Peel.
PubMed:Bioactive compounds and sensory quality of black and white mulberries grown in Spain.
PubMed:Hepatoprotective properties of the Indian gooseberry (Emblica officinalis Gaertn): a review.
PubMed:Thermal stability of liquid antioxidative extracts from pomegranate peel.
PubMed:The anti-biofilm potential of pomegranate (Punica granatum L.) extract against human bacterial and fungal pathogens.
PubMed:Changes on indigenous microbiota, colour, bioactive compounds and antioxidant activity of pasteurised pomegranate juice.
PubMed:Chemical composition of polyphenols extracted from strawberry pomace and their effect on physiological properties of diets supplemented with different types of dietary fibre in rats.
PubMed:Evaluation of acute and subacute toxicity and mutagenic activity of the aqueous extract of pecan shells [Carya illinoinensis (Wangenh.) K. Koch].
PubMed:In vitro antioxidant and antiproliferative effects of ellagic acid and its colonic metabolite, urolithins, on human bladder cancer T24 cells.
PubMed:Stability and oxidation products of hydrolysable tannins in basic conditions detected by HPLC/DAD-ESI/QTOF/MS.
PubMed:Phenolic-rich extract from the Costa Rican guava (Psidium friedrichsthalianum) pulp with antioxidant and anti-inflammatory activity. Potential for COPD therapy.
PubMed:Biological significance of urolithins, the gut microbial ellagic Acid-derived metabolites: the evidence so far.
PubMed:Specific phenolic compounds and sensory properties of a new dealcoholized red wine with pomegranate (Punica granatum L.) extract.
PubMed:Oxidation of fatty acid may be enhanced by a combination of pomegranate fruit phytochemicals and acetic acid in HepG2 cells.
PubMed:Preventive and prophylactic mechanisms of action of pomegranate bioactive constituents.
PubMed:Alteration of the content of primary and secondary metabolites in strawberry fruit by Colletotrichum nymphaeae infection.
PubMed:The pharmacological use of ellagic acid-rich pomegranate fruit.
PubMed:Antioxidant and anti-inflammatory in vitro activities of phenolic compounds from tropical highland blackberry (Rubus adenotrichos).
PubMed:Ultra-HPLC-MS(n) (Poly)phenolic profiling and chemometric analysis of juices from ancient Punica granatum L. Cultivars: a nontargeted approach.
PubMed:Bioactive polyphenols from muscadine grape and blackcurrant stably concentrated onto protein-rich matrices for topical applications.
PubMed:Ellagic acid attenuates bleomycin and cyclophosphamide-induced pulmonary toxicity in Wistar rats.
PubMed:Chemical composition of two different extracts of berries harvested in Serbia.
PubMed:The gut microbiota ellagic acid-derived metabolite urolithin A and its sulfate conjugate are substrates for the drug efflux transporter breast cancer resistance protein (ABCG2/BCRP).
PubMed:Antifungal ellagitannin isolated from Euphorbia antisyphilitica Zucc.
PubMed:Fungal biodegradation of pomegranate ellagitannins.
PubMed:Exploitation of the health-promoting and sensory properties of organic pomegranate (Punica granatum L.) juice through lactic acid fermentation.
PubMed:Ellagic acid derivatives, ellagitannins, proanthocyanidins and other phenolics, vitamin C and antioxidant capacity of two powder products from camu-camu fruit (Myrciaria dubia).
PubMed:Ellagic acid and derivatives from Cochlospermum angolensis Welw. Extracts: HPLC-DAD-ESI/MS(n) profiling, quantification and in vitro anti-depressant, anti-cholinesterase and anti-oxidant activities.
PubMed:Extraction/oxidation kinetics of low molecular weight compounds in wine brandy resulting from different ageing technologies.
PubMed:Innovative microwave-assisted hydrolysis of ellagitannins and quantification as ellagic acid equivalents.
PubMed:Identification of novel dietary phytochemicals inhibiting the efflux transporter breast cancer resistance protein (BCRP/ABCG2).
PubMed:Polyphenols are responsible for the proapoptotic properties of pomegranate juice on leukemia cell lines.
PubMed:Comparison of dynamic viscoelastic and physicochemical properties of pressurised and pasteurised longan juices with xanthan addition.
PubMed:Protective effect of Paeonia anomala extracts and constituents against tert-butylhydroperoxide-induced oxidative stress in HepG2 cells.
PubMed:Sustained deficit irrigation affects the colour and phytochemical characteristics of pomegranate juice.
PubMed:Characterization of ellagitannins, gallotannins, and bound proanthocyanidins from California almond (Prunus dulcis) varieties.
PubMed:HPLC determination of phenolic acids, flavonoids and juglone in walnut leaves.
PubMed:Composition of native Australian herbs polyphenolic-rich fractions and in vitro inhibitory activities against key enzymes relevant to metabolic syndrome.
PubMed:Textural characteristic, antioxidant activity, sugar, organic acid, and phenolic profiles of 10 promising jujube (Ziziphus jujuba Mill.) selections.
PubMed:Bioactive compounds and phenolic-linked functionality of powdered tropical fruit residues.
PubMed:Liquid chromatographic/electrospray ionization tandem mass spectrometric study of polyphenolic composition of four cultivars of Fragaria vesca L. berries and their comparative evaluation.
PubMed:The potential of extracts of Caryocar villosum pulp to scavenge reactive oxygen and nitrogen species.
PubMed:Spectrofluorimetric determination of ellagic acid in brandy.
PubMed:Nanoencapsulation of polyphenols for protective effect against colon-rectal cancer.
PubMed:Unique bioactive polyphenolic profile of guava (Psidium guajava) budding leaf tea is related to plant biochemistry of budding leaves in early dawn.
PubMed:Ellagic acid and polyhydroxylated urolithins are potent catalytic inhibitors of human topoisomerase II: an in vitro study.
PubMed:The combination of analytical-scale HPLC separation with a TR-FRET assay to investigate JAK2 inhibitory compounds in a Boysenberry drink.
PubMed:Analysis of hydrolyzable tannins and other phenolic compounds in emblic leafflower (Phyllanthus emblica L.) fruits by high performance liquid chromatography-electrospray ionization mass spectrometry.
PubMed:Ultra high-performance liquid chromatography with high-resolution mass spectrometry analysis of African mango (Irvingia gabonensis) seeds, extract, and related dietary supplements.
PubMed:Inhibitory effects of water extract from longan twigs on mutation and nitric oxide production.
PubMed:Metabolite profiling of jaboticaba (Myrciaria cauliflora) and other dark-colored fruit juices.
PubMed:Storage stability of sterilized liquid extracts from pomegranate peel.
PubMed:Phytonutrient intake by adults in the United States in relation to fruit and vegetable consumption.
PubMed:Ellagitannin metabolites, urolithin A glucuronide and its aglycone urolithin A, ameliorate TNF-α-induced inflammation and associated molecular markers in human aortic endothelial cells.
PubMed:Identification and quantification, by HPLC-DAD-MS/MS, of carotenoids and phenolic compounds from the Amazonian fruit Caryocar villosum.
PubMed:Inhibition of estrogen-mediated mammary tumorigenesis by blueberry and black raspberry.
PubMed:Evaluation of food-drug interaction of guava leaf tea.
PubMed:ID-CUBE direct analysis in real time high-resolution mass spectrometry and its capabilities in the identification of phenolic components from the green leaves of Bergenia crassifolia L.
PubMed:Ellagic acid attenuates high-carbohydrate, high-fat diet-induced metabolic syndrome in rats.
PubMed:High-performance liquid chromatography-mass spectrometry and evaporative light-scattering detector to compare phenolic profiles of muscadine grapes.
PubMed:Development of colour and firmness in strawberry crops is UV light sensitive, but colour is not a good predictor of several quality parameters.
PubMed:Protective effect of ellagic acid (EA) on micronucleus formation induced by N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) in mammalian cells, in in vitro assays and in vivo.
PubMed:Intestinal ellagitannin metabolites ameliorate cytokine-induced inflammation and associated molecular markers in human colon fibroblasts.
PubMed:Ellagic acid modulates antioxidant status, ornithine decarboxylase expression, and aberrant crypt foci progression in 1,2-dimethylhydrazine-instigated colon preneoplastic lesions in rats.
PubMed:Metastable radicals and intrinsic chemiluminescence from soy proteins.
PubMed:Abrasive stripping square-wave voltammetry of blackberry, raspberry, strawberry, pomegranate, and sweet and blue potatoes.
PubMed:Fatty acid synthase inhibitors separated from oiltea camellia by high-speed counter-current chromatography.
PubMed:Prediction of effect of natural antioxidant compounds on hazelnut oil oxidation by adaptive neuro-fuzzy inference system and artificial neural network.
PubMed:Pomological features, nutritional quality, polyphenol content analysis, and antioxidant properties of domesticated and 3 wild ecotype forms of raspberries (Rubus idaeus L.).
PubMed:Ellagic acid protects human keratinocyte (HaCaT) cells against UVA-induced oxidative stress and apoptosis through the upregulation of the HO-1 and Nrf-2 antioxidant genes.
PubMed:Survey of antioxidant capacity and phenolic composition of blueberry, blackberry, and strawberry in Nanjing.
PubMed:Influence of berry polyphenols on receptor signaling and cell-death pathways: implications for breast cancer prevention.
PubMed:Assay dilution factors confound measures of total antioxidant capacity in polyphenol-rich juices.
PubMed:Antioxidant activity of isolated ellagitannins from red raspberries and cloudberries.
PubMed:Comparison of chemical composition and antioxidant capacity of commercially available blueberry and blackberry wines in Illinois.
PubMed:Potential dietary sources of ellagic acid and other antioxidants among fruits consumed in Brazil: jabuticaba (Myrciaria jaboticaba (Vell.) Berg).
PubMed:Pomegranate as a functional food and nutraceutical source.
PubMed:Strawberry processing does not affect the production and urinary excretion of urolithins, ellagic acid metabolites, in humans.
PubMed:Hepatoprotection of Gentiana scabra extract and polyphenols in liver of carbon tetrachloride-intoxicated mice.
PubMed:Anti-inflammatory effects of polyphenolic-enriched red raspberry extract in an antigen-induced arthritis rat model.
PubMed:Effect of rosehip (Rosa canina L.) phytochemicals on stable free radicals and human cancer cells.
PubMed:Phytonutrient Intake by Adults in the United States in Relation to Fruit and Vegetable Consumption.
PubMed:Variations in antioxidant properties of strawberries grown in Brazilian savannah and harvested in different seasons.
PubMed:Dietary ellagic acid attenuates oxidized LDL uptake and stimulates cholesterol efflux in murine macrophages.
PubMed:The antioxidant potency of Punica granatum L. Fruit peel reduces cell proliferation and induces apoptosis on breast cancer.
PubMed:Chemical and antidiarrheal studies of Plinia cauliflora.
PubMed:Blackberry seed extracts and isolated polyphenolic compounds showing protective effect on human lymphocytes DNA.
PubMed:Identification and quantification of phenolic compounds in bambangan (Mangifera pajang Kort.) peels and their free radical scavenging activity.
PubMed:Antioxidant capacities and total phenolic contents increase with gamma irradiation in two types of Malaysian honey.
PubMed:Purification and characterization of polyphenols from chestnut astringent skin.
PubMed:Red wine: a source of potent ligands for peroxisome proliferator-activated receptor γ.
PubMed:Structure and function of the oxidation products of polyphenols and identification of potent lipoxygenase inhibitors from Fe-catalyzed oxidation of resveratrol.
PubMed:Gastroprotective and ulcer-healing mechanisms of ellagic acid in experimental rats.
PubMed:Comparison of different extraction solvent mixtures for characterization of phenolic compounds in strawberries.
PubMed:Ellagic acid inhibits oxidized low-density lipoprotein (OxLDL)-induced metalloproteinase (MMP) expression by modulating the protein kinase C-α/extracellular signal-regulated kinase/peroxisome proliferator-activated receptor γ/nuclear factor-κB (PKC-α/ERK/PPAR-γ/NF-κB) signaling pathway in endothelial cells.
PubMed:Phytochemical characterisation for industrial use of pomegranate (Punica granatum L.) cultivars grown in Spain.
PubMed:Identification and quantification of short oligomeric proanthocyanidins and other polyphenols in boysenberry seeds and juice.
PubMed:Antioxidant capacity interactions and a chemical/structural model of phenolic compounds found in strawberries.
PubMed:Oral administration of Trapa taiwanensis Nakai fruit skin extracts conferring hepatoprotection from CCl4-caused injury.
PubMed:Assessment of the protective effects of selected dietary anticarcinogens against DNA damage and cytogenetic effects induced by benzo[a]pyrene in C57BL/6J mice.
PubMed:Effect of toasting intensity at cooperage on phenolic compounds in acacia (Robinia pseudoacacia) heartwood.
PubMed:Fabrication of nanoparticles using partially purified pomegranate ellagitannins and gelatin and their apoptotic effects.
PubMed:UV and MS identification of Urolithins and Nasutins, the bioavailable metabolites of ellagitannins and ellagic acid in different mammals.
PubMed:Structural requirements for mutation formation from polycyclic aromatic hydrocarbon dihydrodiol epoxides in their interaction with food chemopreventive compounds.
PubMed:Improvement of obesity phenotype by Chinese sweet leaf tea (Rubus suavissimus) components in high-fat diet-induced obese rats.
PubMed:Phenolic compounds and antioxidant activity of kernels and shells of Mexican pecan (Carya illinoinensis).
PubMed:Analysis by high-performance liquid chromatography diode array detection mass spectrometry of phenolic compounds in fruit of Eucalyptus globulus cultivated in Algeria.
PubMed:In vitro antioxidant and inhibitory potential of Terminalia bellerica and Emblica officinalis fruits against LDL oxidation and key enzymes linked to type 2 diabetes.
PubMed:Characterization of bioactive compounds from raw and ripe Mangifera indica L. peel extracts.
PubMed:Antioxidant assay-guided purification and LC determination of ellagic acid in pomegranate peel.
PubMed:Isolation and identification of radical scavenging and tyrosinase inhibition of polyphenols from Tibouchina semidecandra L.
PubMed:Oenothera paradoxa defatted seeds extract and its bioactive component penta-O-galloyl-β-D-glucose decreased production of reactive oxygen species and inhibited release of leukotriene B4, interleukin-8, elastase, and myeloperoxidase in human neutrophils.
PubMed:Use of microfungi in the treatment of oak chips: possible effects on wine.
PubMed:Ellagic acid inhibits oxidized LDL-mediated LOX-1 expression, ROS generation, and inflammation in human endothelial cells.
PubMed:Phenolic compounds in chestnut (Castanea sativa Mill.) heartwood. Effect of toasting at cooperage.
PubMed:Polyphenol contents and antioxidant activity of lyophilized aqueous extract of propolis from Erzurum, Turkey.
PubMed:Preparation method and stability of ellagic acid-rich pomegranate fruit peel extract.
PubMed:Evaluation of antiproliferative, anti-type 2 diabetes, and antihypertension potentials of ellagitannins from strawberries (Fragaria × ananassa Duch.) using in vitro models.
PubMed:Dietary antioxidants in the prevention of hepatocarcinogenesis: a review.
PubMed:Inhibitory effects of whisky congeners on IgE-mediated degranulation in rat basophilic leukemia RBL-2H3 cells and passive cutaneous anaphylaxis reaction in mice.
PubMed:Identification of natural antimicrobial substances in red muscadine juice against Cronobacter sakazakii.
PubMed:Effect of dehydration on raspberries: polyphenol and anthocyanin retention, antioxidant capacity, and antiadipogenic activity.
PubMed:Influence of cultivation system on bioactive molecules synthesis in strawberries: spin-off on antioxidant and antiproliferative activity.
PubMed:The influence of pomegranate by-product and punicalagins on selected groups of human intestinal microbiota.
PubMed:The effect of lutein, sesamol, ellagic acid and olive leaf extract on lipid oxidation and oxymyoglobin oxidation in bovine and porcine muscle model systems.
PubMed:Ellagic acid and polyphenolics present in walnut kernels inhibit in vitro human peripheral blood mononuclear cell proliferation and alter cytokine production.
PubMed:Evaluation of the effects of selected phytochemicals on quality indices and sensorial properties of raw and cooked pork stored in different packaging systems.
PubMed:Effect of lutein, sesamol, ellagic acid and olive leaf extract on the quality and shelf-life stability of packaged raw minced beef patties.
PubMed:Profiling and accurate quantification of Rubus ellagitannins and ellagic acid conjugates using direct UPLC-Q-TOF HDMS and HPLC-DAD analysis.
PubMed:Absence of pomegranate ellagitannins in the majority of commercial Pomegranate extracts: implications for standardization and quality control.
PubMed:Secondary plant substances in various extracts of the leaves, fruits, stem and bark of Caraipa densifolia Mart.
PubMed:NF-kappaB-dependent anti-inflammatory activity of urolithins, gut microbiota ellagic acid-derived metabolites, in human colonic fibroblasts.
PubMed:Chemical composition and antioxidant/antidiabetic potential of Brazilian native fruits and commercial frozen pulps.
PubMed:Identification of major phenolic compounds from Nephelium lappaceum L. and their antioxidant activities.
PubMed:Antioxidant capacity, phenolic content, and profiling of phenolic compounds in the seeds, skin, and pulp of Vitis rotundifolia (Muscadine Grapes) As determined by HPLC-DAD-ESI-MS(n).
PubMed:Phenolic compounds in cherry ( Prunus avium ) heartwood with a view to their use in cooperage.
PubMed:Bioavailability of anthocyanins and ellagitannins following consumption of raspberries by healthy humans and subjects with an ileostomy.
PubMed:Dietary compound ellagic acid alleviates skin wrinkle and inflammation induced by UV-B irradiation.
PubMed:Screening of phenolic antioxidants for their inhibitory activity against foodborne Staphylococcus aureus strains.
PubMed:Comparison of the polyphenolic composition and antioxidant activity of European commercial fruit juices.
PubMed:Evaluation of the polyphenol composition and antioxidant activity of African variety of Dacryodes edulis (G.Don) H.J Lam fruit.
PubMed:HPLC-MS analysis of proanthocyanidin oligomers and other phenolics in 15 strawberry cultivars.
PubMed:Effects of fruit ellagitannin extracts, ellagic acid, and their colonic metabolite, urolithin A, on Wnt signaling.
PubMed:In vitro and in vivo antioxidant properties and DNA damage protective activity of green fruit of Ficus glomerata.
PubMed:Influences of harvest date and location on the levels of beta-carotene, ascorbic acid, total phenols, the in vitro antioxidant capacity, and phenolic profiles of five commercial varieties of mango (Mangifera indica L.).
PubMed:Occurrence of urolithins, gut microbiota ellagic acid metabolites and proliferation markers expression response in the human prostate gland upon consumption of walnuts and pomegranate juice.
PubMed:Anti-glycative and anti-inflammatory effects of caffeic acid and ellagic acid in kidney of diabetic mice.
PubMed:Electron-beam irradiation effects on phytochemical constituents and antioxidant capacity of pecan kernels [ Carya illinoinensis (Wangenh.) K. Koch] during storage.
PubMed:Urolithins, intestinal microbial metabolites of Pomegranate ellagitannins, exhibit potent antioxidant activity in a cell-based assay.
PubMed:[Analysis of the extraction of red pellicle of walnut (Juglans regia L.) by ultraviolet-visible spectra and HPLC-ESI-MS(n)].
PubMed:Color and polyphenolic stability in extracts produced from muscadine grape (Vitis rotundifolia) pomace.
PubMed:Interaction of polyphenolic metabolites with human serum albumin: a circular dichroism study.
PubMed:Gastrointestinal microflora, food components and colon cancer prevention.
PubMed:Consumption of some polyphenols reduces fecal deoxycholic acid and lithocholic acid, the secondary bile acids of risk factors of colon cancer.
PubMed:The effect of pomegranate (Punica granatum L.) byproducts and ellagitannins on the growth of human gut bacteria.
PubMed:Ellagic acid and its methyl-derivatives inhibit a newly found nitratase activity.
PubMed:Dissimilar in vitro and in vivo effects of ellagic acid and its microbiota-derived metabolites, urolithins, on the cytochrome P450 1A1.
PubMed:Phenolic content and radical scavenging capacity of berries and related jams from certificated area in Serbia.
PubMed:Characterization of a rare triterpenoid and minor phenolic compounds in the root bark of Anisophyllea dichostyla R. Br.
PubMed:Enhanced oral bioavailability and antioxidant profile of ellagic acid by phospholipids.
PubMed:Gene expression, cell cycle arrest and MAPK signalling regulation in Caco-2 cells exposed to ellagic acid and its metabolites, urolithins.
PubMed:Oxidative DNA damage protective activity, antioxidant and anti-quorum sensing potentials of Moringa oleifera.
PubMed:Marker constituents of the natural antioxidant Eucalyptus leaf extract for the evaluation of food additives.
PubMed:Purification of a water extract of Chinese sweet tea plant (Rubus suavissimus S. Lee) by alcohol precipitation.
PubMed:Oxygen and nitrogen reactive species are effectively scavenged by Eucalyptus globulus leaf water extract.
PubMed:Effect of drying methods with the application of vacuum microwaves on the bioactive compounds, color, and antioxidant activity of strawberry fruits.
PubMed:Antioxidant and anti-quorum sensing activities of green pod of Acacia nilotica L.
PubMed:Inactivation of Enterobacter sakazakii by water-soluble muscadine seed extracts.
PubMed:Phenolic compounds in Rosaceae fruits from Ecuador.
PubMed:Quantitative and fingerprint analyses of Chinese sweet tea plant ( Rubus suavissimus S. Lee).
PubMed:Food ellagitannins-occurrence, effects of processing and storage.
PubMed:Active compounds from Lagerstroemia speciosa, insulin-like glucose uptake-stimulatory/inhibitory and adipocyte differentiation-inhibitory activities in 3T3-L1 cells.
PubMed:Antioxidant status in humans after consumption of blackberry (Rubus fruticosus L.) juices with and without defatted milk.
PubMed:Phytophenols in whisky lower blood acetaldehyde level by depressing alcohol metabolism through inhibition of alcohol dehydrogenase 1 (class I) in mice.
PubMed:Simultaneous analysis of ellagic acid and coenzyme Q(10) by derivative spectroscopy and HPLC.
PubMed:Protein glycation inhibitors from the fruiting body of Phellinus linteus.
PubMed:Effect of antioxidant phytochemicals on the hepatic tumor promoting activity of 3,3',4,4'-tetrachlorobiphenyl (PCB-77).
PubMed:Quantitative analysis of antiradical phenolic constituents from fourteen edible Myrtaceae fruits.
PubMed:Antimicrobial effect of water-soluble muscadine seed extracts on Escherichia coli O157:H7.
PubMed:Isolation and structure of whiskey polyphenols produced by oxidation of oak wood ellagitannins.
PubMed:Towards fruitful metabolomics: high throughput analyses of polyphenol composition in berries using direct infusion mass spectrometry.
PubMed:Pomegranate juice and extracts provide similar levels of plasma and urinary ellagitannin metabolites in human subjects.
PubMed:The effects of dietary phenolic compounds on cytokine and antioxidant production by A549 cells.
PubMed:Functionality of bioactive compounds in Brazilian strawberry (Fragaria x ananassa Duch.) cultivars: evaluation of hyperglycemia and hypertension potential using in vitro models.
PubMed:Oak ellagitannins suppress the phosphorylation of the epidermal growth factor receptor in human colon carcinoma cells.
PubMed:Inhibitory constituents of aldose reductase in the fruiting body of Phellinus linteus.
PubMed:Cytotoxic chalcones and antioxidants from the fruits of a Syzygium samarangense (Wax Jambu).
PubMed:Ellagic acid production by Aspergillus niger in solid state fermentation of pomegranate residues.
PubMed:Isolation and identification of strawberry phenolics with antioxidant and human cancer cell antiproliferative properties.
PubMed:Pomegranate phenolics from the peels, arils, and flowers are antiatherogenic: studies in vivo in atherosclerotic apolipoprotein e-deficient (E 0) mice and in vitro in cultured macrophages and lipoproteins.
PubMed:Safety assessment of ellagic acid, a food additive, in a subchronic toxicity study using F344 rats.
PubMed:Reactive oxygen scavenging activity of matured whiskey and its active polyphenols.
PubMed:Iberian pig as a model to clarify obscure points in the bioavailability and metabolism of ellagitannins in humans.
PubMed:Nutraceuticals: facts and fiction.
PubMed:Analysis of phenolic compounds in two blackberry species (Rubus glaucus and Rubus adenotrichus) by high-performance liquid chromatography with diode array detection and electrospray ion trap mass spectrometry.
PubMed:Pomegranate ellagitannin-derived metabolites inhibit prostate cancer growth and localize to the mouse prostate gland.
PubMed:The efficacy of protective effects of tannic acid, gallic acid, ellagic acid, and propyl gallate against hydrogen peroxide-induced oxidative stress and DNA damages in IMR-90 cells.
PubMed:Effects of various plant polyphenols on bladder carcinogen benzidine-induced mutagenicity.
PubMed:An exploratory study of the nutritional composition of Tanoak (Lithocarpus densiflorus) acorns after potassium phosphonate treatment.
PubMed:Polyphenol composition and antioxidant activity in strawberry purees; impact of achene level and storage.
PubMed:The bioavailability of raspberry anthocyanins and ellagitannins in rats.
PubMed:Phenolic compounds, organic acids profiles and antioxidative properties of beefsteak fungus (Fistulina hepatica).
PubMed:Characterization of phenolic compounds in strawberry (Fragaria x ananassa) fruits by different HPLC detectors and contribution of individual compounds to total antioxidant capacity.
PubMed:Total phenol, antioxidant and free radical scavenging activities of some medicinal plants.
PubMed:Primary and secondary metabolite composition of kernels from three cultivars of Portuguese chestnut (Castanea sativa Mill.) at different stages of industrial transformation.
PubMed:Evidence of anti-obesity effects of the pomegranate leaf extract in high-fat diet induced obese mice.
PubMed:Benzothiadiazole induces the accumulation of phenolics and improves resistance to powdery mildew in strawberries.
PubMed:Assessment of the differences in the phenolic composition of five strawberry cultivars (Fragaria x ananassa Duch.) grown in two different soilless systems.
PubMed:Contents of anthocyanins and ellagitannins in selected foods consumed in Finland.
PubMed:Determination of ellagic acid in pseudofruits of some species of roses.
PubMed:Novel lipid-peroxidation- and cyclooxygenase-inhibitory tannins from Picrorhiza kurroa seeds.
PubMed:Effects of oral administration of ellagic acid-rich pomegranate extract on ultraviolet-induced pigmentation in the human skin.
PubMed:Absorption, metabolism, and antioxidant effects of pomegranate (Punica granatum l.) polyphenols after ingestion of a standardized extract in healthy human volunteers.
PubMed:Isolation, purification and identification of ellagic acid derivatives, catechins, and procyanidins from the root bark of Anisophyllea dichostyla R. Br.
PubMed:Evaluation of free radical scavenging and antityrosinase activities of standardized longan fruit extract.
PubMed:The inhibition of human glutathione S-transferases activity by plant polyphenolic compounds ellagic acid and curcumin.
PubMed:Polyphenolic profiles and antioxidant activities of heartnut (Juglans ailanthifolia Var. cordiformis) and Persian walnut (Juglans regia L.).
PubMed:Chemical composition of clarified bayberry (Myrica rubra Sieb. et Zucc.) juice sediment.
PubMed:Understanding the native Californian diet: Identification of condensed and hydrolyzable tannins in tanoak acorns (Lithocarpus densiflorus).
PubMed:Growth-inhibiting activity of active component isolated from Terminalia chebula fruits against intestinal bacteria.
PubMed:Total antioxidant activity and fiber content of select Florida-grown tropical fruits.
PubMed:[Constituents relating to anti-oxidative and alpha-glucosidase inhibitory activities in Yacon aerial part extract].
PubMed:Induction of cell death in Caco-2 human colon carcinoma cells by ellagic acid rich fractions from muscadine grapes (Vitis rotundifolia).
PubMed:Ellagic acid and natural sources of ellagitannins as possible chemopreventive agents against intestinal tumorigenesis in the Min mouse.
PubMed:Protection against esophageal cancer in rodents with lyophilized berries: potential mechanisms.
PubMed:Role of antioxidants in prophylaxis and therapy: A pharmaceutical perspective.
PubMed:Concentration and mean degree of polymerization of Rubus ellagitannins evaluated by optimized acid methanolysis.
PubMed:Beware of pomegranates bearing 40% ellagic Acid.
PubMed:Influence of fertilization, mulch color, early forcing, fruit order, planting date, shading, growing Environment, and genotype on the contents of selected phenolics in strawberry (Fragaria x ananassa Duch.) fruits.
PubMed:Molecular targets of dietary agents for prevention and therapy of cancer.
PubMed:Urolithins, ellagic acid-derived metabolites produced by human colonic microflora, exhibit estrogenic and antiestrogenic activities.
PubMed:Pomegranate juice, total pomegranate ellagitannins, and punicalagin suppress inflammatory cell signaling in colon cancer cells.
PubMed:The dietary hydrolysable tannin punicalagin releases ellagic acid that induces apoptosis in human colon adenocarcinoma Caco-2 cells by using the mitochondrial pathway.
PubMed:E-cinnamic acid derivatives and phenolics from Chilean strawberry fruits, Fragaria chiloensis ssp. chiloensis.
PubMed:Evaluation of estrogenic/antiestrogenic activity of ellagic acid via the estrogen receptor subtypes ERalpha and ERbeta.
PubMed:Isolation and structure elucidation of phenolic compounds from longan (Dimocarpus longan Lour.) seed by high-performance liquid chromatography-electrospray ionization mass spectrometry.
PubMed:Phenolic contents and antioxidant activity of some food and medicinal plants.
PubMed:Phenolic acids, syringaldehyde, and juglone in fruits of different cultivars of Juglans regia L.
PubMed:Identification of ellagic acid conjugates and other polyphenolics in muscadine grapes by HPLC-ESI-MS.
PubMed:Identification of urolithin a as a metabolite produced by human colon microflora from ellagic acid and related compounds.
PubMed:Enhancing health benefits of berries through phenolic antioxidant enrichment: focus on cranberry.
PubMed:Phenolic composition and antioxidant activities in flesh and achenes of strawberries (Fragaria ananassa).
PubMed:Determination of mechanism of flock sediment formation in tea beverages.
PubMed:Identification and quantification of polyphenolic compounds in Longan (Euphoria longana Lam.) fruit.
PubMed:Ellagic acid potentiates the effect of quercetin on p21waf1/cip1, p53, and MAP-kinases without affecting intracellular generation of reactive oxygen species in vitro.
PubMed:Ellagic acid and quercetin interact synergistically with resveratrol in the induction of apoptosis and cause transient cell cycle arrest in human leukemia cells.
PubMed:Metabolism of antioxidant and chemopreventive ellagitannins from strawberries, raspberries, walnuts, and oak-aged wine in humans: identification of biomarkers and individual variability.
PubMed:Chemical composition of caneberry (Rubus spp.) seeds and oils and their antioxidant potential.
PubMed:In vitro anti-proliferative activities of ellagic acid.
PubMed:Effects of tannic acid and its related compounds on food mutagens or hydrogen peroxide-induced DNA strands breaks in human lymphocytes.
PubMed:Comprehensive study on vitamin C equivalent antioxidant capacity (VCEAC) of various polyphenolics in scavenging a free radical and its structural relationship.
PubMed:Identification and quantification of phenolic compounds in berries of Fragaria and Rubus species (family Rosaceae).
PubMed:Natural products for dental caries prevention.
PubMed:Bioavailability of ellagic acid in human plasma after consumption of ellagitannins from pomegranate (Punica granatum L.) juice.
PubMed:The potent in vitro antioxidant ellagitannins from pomegranate juice are metabolised into bioavailable but poor antioxidant hydroxy-6H-dibenzopyran-6-one derivatives by the colonic microflora of healthy humans.
PubMed:Comparison between cachaça and rum using pattern recognition methods.
PubMed:Antioxidants, low molecular weight carbohydrates, and total antioxidant capacity in strawberries (Fragaria x ananassa): effects of cultivar, ripening, and storage.
PubMed:Potential impact of strawberries on human health: a review of the science.
PubMed:Phytochemical inhibition of aflatoxigenicity in Aspergillus flavus by constituents of walnut (Juglans regia).
PubMed:Phenolic composition of strawberry genotypes at different maturation stages.
PubMed:Protein-lipid interactions during liposome oxidation with added anthocyanin and other phenolic compounds.
PubMed:Fruit maturity and juice extraction influences ellagic acid derivatives and other antioxidant polyphenolics in muscadine grapes.
PubMed:Major flavonoids in grape seeds and skins: antioxidant capacity of catechin, epicatechin, and gallic acid.
PubMed:Phenolic compounds and fatty acids from acorns (Quercus spp.), the main dietary constituent of free-ranged Iberian pigs.
PubMed:Antioxidative capacity of extracts and constituents in Cornus capitata adventitious roots.
PubMed:Phenolic content and antioxidant capacity of muscadine grapes.
PubMed:Low concentrations of quercetin and ellagic acid synergistically influence proliferation, cytotoxicity and apoptosis in MOLT-4 human leukemia cells.
PubMed:[Studies on the chemical constituents in the leaves of Cyclocarya paliurus].
PubMed:Repeated oral administration of high doses of the pomegranate ellagitannin punicalagin to rats for 37 days is not toxic.
PubMed:Evaluation of the bioavailability and metabolism in the rat of punicalagin, an antioxidant polyphenol from pomegranate juice.
PubMed:Effect of freezing and storage on the phenolics, ellagitannins, flavonoids, and antioxidant capacity of red raspberries.
PubMed:Ellagitannins, flavonoids, and other phenolics in red raspberries and their contribution to antioxidant capacity and vasorelaxation properties.
PubMed:Ellagic acid and ellagitannins affect on sedimentation in muscadine juice and wine.
PubMed:Determination of free and total phenolic acids in plant-derived foods by HPLC with diode-array detection.
PubMed:Antioxidant activity and phenolic content of Oregon caneberries.
PubMed:Ellagic acid and flavonoid antioxidant content of muscadine wine and juice.
PubMed:[Prospect of the development of new bactericidal drugs against Helicobacter pylori for eradication therapy].
PubMed:Effects of lyophilized black raspberries on azoxymethane-induced colon cancer and 8-hydroxy-2'-deoxyguanosine levels in the Fischer 344 rat.
PubMed:Influence of cultivar on quality parameters and chemical composition of strawberry fruits grown in Brazil.
PubMed:Phenolic compounds and antioxidant capacity of Georgia-grown blueberries and blackberries.
PubMed:Free radical studies of ellagic acid, a natural phenolic antioxidant.
PubMed:[Studies on procedure for sample preparation of ellagic acid in several kinds of foodstuffs].
PubMed:Effect of processing and storage on the antioxidant ellagic acid derivatives and flavonoids of red raspberry (Rubus idaeus) jams.
PubMed:Chemoprevention of esophageal tumorigenesis by dietary administration of lyophilized black raspberries.
PubMed:Use of methanolysis for the determination of total ellagic and gallic acid contents of wood and food products.
PubMed:Antioxidant activity of pomegranate juice and its relationship with phenolic composition and processing.
PubMed:Ellagic acid, vitamin C, and total phenolic contents and radical scavenging capacity affected by freezing and frozen storage in raspberry fruit.
PubMed:Identification of flavonoid markers for the botanical origin of Eucalyptus honey.
PubMed:Mutagenicity and antimutagenicity studies of tannic acid and its related compounds.
PubMed:Assessment of the antioxidant potential of scotch whiskeys by electron spin resonance spectroscopy: relationship to hydroxyl-containing aromatic components.
PubMed:Phenolic constituents, furans, and total antioxidant status of distilled spirits.
PubMed:Evaluation of the antioxidant activity of environmental plants: activity of the leaf extracts from seashore plants.
PubMed:Tannins, xenobiotic metabolism and cancer chemoprevention in experimental animals.
PubMed:Prevention of N-nitrosodiethylamine-induced lung tumorigenesis by ellagic acid and quercetin in mice.
PubMed:Antimutagenic effects of natural phenolic compounds in beans.
PubMed:Effects of dietary anticarcinogens on rat gastrointestinal glutathione S-transferase theta 1-1 levels.
PubMed:In vitro attenuation of nitric oxide production in C6 astrocyte cell culture by various dietary compounds.
PubMed:[Phenolic acid intake of adults in a Bavarian subgroup of the national food consumption survey].
PubMed:Protective effect of food additives on aflatoxin-induced mutagenicity and hepatocarcinogenicity.
PubMed:Experimental evidence for cancer preventive elements in foods.
PubMed:Organ specific, protocol dependent modulation of 7,12-dimethylbenz[a]anthracene carcinogenesis in rainbow trout (Oncorhynchus mykiss) by dietary ellagic acid.
PubMed:Anti-genotoxic effects in mice after the interaction between coffee and dietary constituents.
PubMed:Pentachlorophenol-induced oxidative DNA damage in mouse liver and protective effect of antioxidants.
PubMed:Influence of nutrients and other dietary materials on cytochrome P-450 enzymes.
PubMed:Chemopreventive effects of beta-carotene, alpha-tocopherol and five naturally occurring antioxidants on initiation of hepatocarcinogenesis by 2-amino-3-methylimidazo[4,5-f]quinoline in the rat.
PubMed:Inhibition of liver microsomal cytochrome P450 activity and metabolism of the tobacco-specific nitrosamine NNK by capsaicin and ellagic acid.
PubMed:Inhibition of aflatoxin-induced liver damage in ducklings by food additives.
PubMed:Reversal of aflatoxin induced liver damage by turmeric and curcumin.
PubMed:Antimutagenicity of ellagic acid towards the food mutagen IQ: investigation into possible mechanisms of action.
PubMed:Ellagic acid effects on the carcinogenicity, DNA-binding and metabolism of 7,12-dimethylbenz(a)anthracene (DMBA).
PubMed:Effects of plant-derived flavonoids and polyphenolic acids on the activity of mutagens from cooked food.
PubMed:Mutagenicity of smoked, dried bonito products.
PubMed:Antimutagenic activity of some naturally occurring compounds towards cigarette-smoke condensate and benzo[a]pyrene in the Salmonella/microsome assay.
PubMed:Inhibition by plant phenols of benzo[a]pyrene-induced nuclear aberrations in mammalian intestinal cells: a rapid in vivo assessment method.
PubMed:Naturally occurring food toxicants: phenolic substances of plant origin common in foods.
 
Notes:
a fused four ring compound occurring free or combined in galls. isolated from the kino of eucalyptus maculata hook and e. hemipholia f. muell. activates factor xii of the blood clotting system which also causes kinin release; used in research and as a dye. Widely distributed in higher plants esp. dicotyledons. Intestinal astringent, dietary role disputed. Nutriceutical with anticancer and antioxidation props. Ellagic acid is a Polyphenol compound found in numerous fruits and vegetables, including, raspberries; Ellagic acid is a polyphenol antioxidant found in numerous fruits and vegetables including raspberries, strawberries, cranberries, walnuts, pecans, pomegranates and other plant foods. The antiproliferative and antioxidant properties of ellagic acid have spurred preliminary research into the potential health benefits of ellagic acid consumption.; and other plant foods. It is often regarded as an antioxidant. Ellagic Acid Clinical Tests on cultured human cells also show that Ellagic acid prevents the destruction of the p53 gene by cancer cells. Additional studies suggest that one of the mechanisms by which Ellagic acid inhibits mutagenesis and carcinogenesis is by forming adducts with DNA, thus masking binding sites to be occupied by the mutagen or carcinogen.; cranberries; pecans; pomegranates; strawberries; walnuts
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