calcium stearate
octadecanoic acid, calcium salt (2:1)
 
Notes:
Used in foods as a flavouring adjuvant, lubricant, release agent, stabiliser and thickener, binder, emulsifier and anticaking agent
  • American International Chemical, LLC.
  • Charkit Chemical
    • Charkit Chemical Corporation
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      Calcium Stearate
       
  • Penta International
    • Penta International Corporation
      Chemistry innovation
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      Product(s):
      03-02900 CALCIUM STEARATE POWDER FCC
       
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calcium octadecanoate (Click)
CAS Number: 1592-23-0Picture of molecule
Other: 105478-11-3
ECHA EINECS - REACH Pre-Reg: 216-472-8
FDA UNII: 776XM7047L
Nikkaji Web: J7.521C
MDL: MFCD00036390
Molecular Weight: 607.02870000
Formula: C36 H70 Ca O4
NMR Predictor: Predict (works with chrome or firefox)
Category: stabilizing agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist: Search
Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
 FDA/DG SANTE Petitions, Reviews, Notices:
181.129, 184.1229 Calcium stearate View-review
FDA Mainterm: CALCIUM STEARATE
FDA Regulation:
FDA PART 169 -- FOOD DRESSINGS AND FLAVORINGS
Subpart B--Requirements for Specific Standardized Food Dressings and Flavorings
Sec. 169.179 Vanilla powder.


FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION
Subpart I--Multipurpose Additives
Sec. 172.863 Salts of fatty acids.


FDA PART 173 -- SECONDARY DIRECT FOOD ADDITIVES PERMITTED IN FOOD FOR HUMAN CONSUMPTION
Subpart D--Specific Usage Additives
Sec. 173.340 Defoaming agents.


FDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS
Subpart C--Substances for Use as Components of Coatings
Sec. 175.300 Resinous and polymeric coatings.


FDA PART 177 -- INDIRECT FOOD ADDITIVES: POLYMERS
Subpart C--Substances for Use Only as Components of Articles Intended for Repeated Use
Sec. 177.2410 Phenolic resins in molded articles.


FDA PART 177 -- INDIRECT FOOD ADDITIVES: POLYMERS
Subpart C--Substances for Use Only as Components of Articles Intended for Repeated Use
Sec. 177.2600 Rubber articles intended for repeated use.


FDA PART 178 -- INDIRECT FOOD ADDITIVES: ADJUVANTS, PRODUCTION AIDS, AND SANITIZERS
Subpart B--Substances Utilized To Control the Growth of Microorganisms
Sec. 178.1010 Sanitizing solutions.


FDA PART 178 -- INDIRECT FOOD ADDITIVES: ADJUVANTS, PRODUCTION AIDS, AND SANITIZERS
Subpart C--Antioxidants and Stabilizers
Sec. 178.2010 Antioxidants and/or stabilizers for polymers.


FDA PART 179 -- IRRADIATION IN THE PRODUCTION, PROCESSING AND HANDLING OF FOOD
Subpart C--Packaging Materials for Irradiated Foods
Sec. 179.45 Packaging materials for use during the irradiation of prepackaged foods.


FDA PART 181 -- PRIOR-SANCTIONED FOOD INGREDIENTS
Subpart B--Specific Prior-Sanctioned Food Ingredients
Sec. 181.29 Stabilizers.


FDA PART 184 -- DIRECT FOOD SUBSTANCES AFFIRMED AS GENERALLY RECOGNIZED AS SAFE
Subpart B--Listing of Specific Substances Affirmed as GRAS
Sec. 184.1229 Calcium stearate.
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Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Melting Point: 179.50 °C. @ 760.00 mm Hg
Boiling Point: 358.00 to  360.00 °C. @ 760.00 mm Hg
Vapor Pressure: 0.000009 mm/Hg @ 25.00 °C. (est)
Flash Point: 324.00 °F. TCC ( 162.22 °C. )
logP (o/w): 8.216 (est)
Soluble in:
 water, 2 mg/L @ 35 °C (exp)
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Organoleptic Properties:
  
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: anticaking agents
cosmetic colorants
emulsion stabilisers
viscosity controlling agents
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Suppliers:
Aceto
Calcium Stearate NF
Acme-Hardesty
Calcium Stearate
Odor: characteristic
Use: Flow Agent, Excipient, Mold Release Agent, Source of Calcium, Tableting Agent. Also used as a PVC Rigid Extrusion Internal/External Lubricant, Polyethylene Chain Length Modifier and as a De-Dusting Agent.
Allan Chemical
Calcium Stearate
American Elements
Calcium Stearate 99%
Odor: characteristic
Use: Calcium Stearate is one of numerous organo-metallic compounds sold by American Elements under the tradename AE Organo-Metallics™ for uses requiring non-aqueous solubility such as recent solar energy and water treatment applications. Calcium Stearate is generally immediately available in most volumes, including bulk quantities. American Elements produces to many standard grades when applicable, including Mil Spec (military grade); ACS, Reagent and Technical Grade; Food, Agricultural and Pharmaceutical Grade; Optical Grade, USP and EP/BP (European Pharmacopoeia/British Pharmacopoeia) and follows applicable ASTM testing standards.
American International Chemical, LLC.
CALCIUM STEARATE E FCC KOSHER
American International Chemical, LLC.
CALCIUM STEARATE FEED GRADE VEGETABLE
American International Chemical, LLC.
CALCIUM STEARATE KOSHER
American International Chemical, LLC.
CALCIUM STEARATE NF KOSHER
American International Chemical, LLC.
CALCIUM STEARATE SP KOSHER
Barium & Chemicals
Calcium Stearate High Purity Grade
Odor: characteristic
Use: water repellent, flatting agent in paints, lubricant in making tablets, emulsions, cements, wax crayons, stabilizer for vinyl resins, mold release agent.
BOC Sciences
For experimental / research use only.
Calcium stearate 98%
Charkit Chemical
CALCIUM STEARATE
ECSA Chemicals
Calcium Stearate
Company Profile
Graham Chemical
Calcium Stearate
Kraft Chemical
Calcium Stearate
Mosselman
Calcium Stearate
Penta International
CALCIUM STEARATE POWDER FCC
Prinova
Calcium Stearate
Silver Fern Chemical
Calcium Stearate
Odor: characteristic
Use: Calcium stearate is carboxylate of calcium that is found in some lubricants and surfactants. Calcium Stearate is a white waxy powder and is also the main component of soap scum.
Songwon Industrial
SONGSTAB™ SC-110
Songwon Industrial
SONGSTAB™ SC-120
Songwon Industrial
SONGSTAB™ SC-130
Strem Chemicals
For experimental / research use only.
Calcium stearate, min. 85%
SysKem Chemie
Calcium Stearate
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50  > 10000 mg/kg
Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 36(4), Pg. 17, 1992.

oral-mouse LD50  > 10000 mg/kg
Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 36(4), Pg. 17, 1992.

intraperitoneal-mouse LD50  > 10000 mg/kg
Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 36(4), Pg. 17, 1992.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
inhalation-mammal (species unspecified) LC > 1241 mg/m3/4H
Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 36(4), Pg. 17, 1992.

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Safety in Use Information:
Category: stabilizing agents
Recommendation for calcium stearate usage levels up to:
 not for fragrance use.
 
Recommendation for calcium stearate flavor usage levels up to:
 not for flavor use.
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Safety References:
European Food Safety Authority (EFSA) reference(s):
Re-evaluation of sodium, potassium and calcium salts of fatty acids (E 470a) and magnesium salts of fatty acids (E 470b) as food additives
View page or View pdf
EPI System: View
NIOSH International Chemical Safety Cards: search
NLM Hazardous Substances Data Bank: Search
Env. Mutagen Info. Center: Search
EPA Substance Registry Services (TSCA): 1592-23-0
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 15324
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: nwg
 calcium octadecanoate
Chemidplus: 0001592230
RTECS: 1592-23-0
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References:
 calcium octadecanoate
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 1592-23-0
Pubchem (cid): 15324
Pubchem (sid): 134978890
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Other Information:
(IUPAC): Atomic Weights of the Elements 2009
(IUPAC): Atomic Weights of the Elements 2009 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
FDA Everything Added to Food in the United States (EAFUS): View
CHEMBL: View
KEGG (GenomeNet): D03310
HMDB (The Human Metabolome Database): Search
FooDB: FDB011517
Haz-Map: View
ChemSpider: View
Wikipedia: View
RSC Learn Chemistry: View
Formulations/Preparations:
•purity: calcium stearate...is compd of calcium with a mixt of solid org acids obtained from fats & consists chiefly of variable proportions of stearic & palmitic acidscontains equivalent of 9-10.5% of calcium oxide. •grades: technical; fcc.
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
 cosmetic colorants 
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Occurrence (nature, food, other): note
 not found in nature
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Synonyms:
 calcium bis(stearate)
 calcium dioctadecanoate
 calcium distearate
 calcium octadecanoate
 calcium stearate FCC bulky
 calcium stearate kosher
 calcium stearate PLC
 calcium stearate SP kosher
 calcium stearate vegetable 50% dispersion
 calcium stearate WLC
 calciumstearate
 flexichem
 octadecanoic acid calcium salt (2:1)
 octadecanoic acid, calcium salt
 octadecanoic acid, calcium salt (2:1)
 stavinor 30
 stearic acid calcium salt
 witco G 339S
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Articles:
PubMed: End-of-life treatment of poly(vinyl chloride) and chlorinated polyethylene by dehydrochlorination in ionic liquids.
PubMed: Impact of drying on solid state modifications and drug distribution in ibuprofen-loaded calcium stearate pellets.
PubMed: The systematic classification of gallbladder stones.
PubMed: Microstructure of calcium stearate matrix pellets: a function of the drying process.
PubMed: Inline monitoring and a PAT strategy for pharmaceutical hot melt extrusion.
PubMed: The effect of lubricants on powder flowability for pharmaceutical application.
PubMed: A microstructural study of gallbladder stones using scanning electron microscopy.
PubMed: TAK-242, a small-molecule inhibitor of Toll-like receptor 4 signalling, unveils similarities and differences in lipopolysaccharide- and lipid-induced inflammation and insulin resistance in muscle cells.
PubMed: Differences in long-term fixation between mobile-bearing and fixed-bearing knee prostheses at ten to 12 years' follow-up: a single-blinded randomised controlled radiostereometric trial.
PubMed: Synergistic effect of calcium stearate and photo treatment on the rate of biodegradation of low density polyethylene spent saline vials.
PubMed: Ibuprofen-loaded calcium stearate pellets: drying-induced variations in dosage form properties.
PubMed: Effects of anticaking agents and relative humidity on the physical and chemical stability of powdered vitamin C.
PubMed: Formulation, development, and performance evaluation of metoclopramide HCl oro-dispersible sustained release tablet.
PubMed: Fixed-point and stratified analysis of the fine structure and composition of five gallstones with Fourier transform infrared (FT-IR) specular reflection spectroscopy.
PubMed: Development of sustained-release lipophilic calcium stearate pellets via hot melt extrusion.
PubMed: Structure and surface coverage of water-based stearate coatings on calcium carbonate nanoparticles.
PubMed: The effect of Zn-Al-hydrotalcites composited with calcium stearate and ╬▓-diketone on the thermal stability of PVC.
PubMed: Extraction of stearate salts from plastic materials used in pharmaceutical applications.
PubMed: Formulation and evaluation of verapamil hydrochloride loaded solid lipid microparticles.
PubMed: Comparison of suture material and technique of closure of subcutaneous fat and skin in caesarean section.
PubMed: Nucleating effect of calcium stearate coated CaCO(3) nanoparticles on polypropylene.
PubMed: On the coating of precipitated calcium carbonate with stearic acid in aqueous medium.
PubMed: Development of lipophilic calcium stearate pellets using ibuprofen as model drug.
PubMed: Effect of pharmaceutical excipients on the stability of trichlormethiazide tablets under humid conditions.
PubMed: Production of calcium-stearate by lipase using hydrogenated beef tallow.
PubMed: Determination of calcium stearate in polyolefin samples by gas chromatographic technique after performing dispersive liquid-liquid microextraction.
PubMed: Activity of intracellular phospholipase A1 and A2 in Giardia lamblia.
PubMed: [The identification of several saturated fatty acids and their salts by means of infrared spectrometry].
PubMed: [Raman spectrometry of several saturated fatty acids and their salts].
PubMed: Acute eosinophilic pneumonia caused by calcium stearate, an additive agent for an oral antihistaminic medication.
PubMed: Release of albumin from oligoester plastic matrices: effect of magnesium oxide and bivalent stearates.
PubMed: Synthesis of high surface area hydroxyapatite nanoparticles by mixed surfactant-mediated approach.
PubMed: Simulation of organic monolayers as templates for the nucleation of calcite crystals.
PubMed: Actions of two naturally occurring saturated N-acyldopamines on transient receptor potential vanilloid 1 (TRPV1) channels.
PubMed: Quantifying the effect of resin type and sterilization method on the degradation of ultrahigh molecular weight polyethylene after 4 years of real-time shelf aging.
PubMed: Long-chain saturated fatty acids induce annexin II translocation to detergent-resistant membranes.
PubMed: [Analysis on infrared spectrum of human body gallstone with comparative method].
PubMed: Trichomonas vaginalis: identification of a phospholipase A-dependent hemolytic activity in a vesicular subcellular fraction.
PubMed: A case of rhinolithiasis in botswana: a mineralogical, microscopic and chemical study.
PubMed: Binding of [99mTc]chondroitin sulfate to scavenger receptors on human chondrocytes as compared to binding of oxidized [125I]LDL on human macrophages.
PubMed: Surface damage in machined ram-extruded and net-shape molded retrieved polyethylene tibial inserts of total knee replacements.
PubMed: The influence of sterilization method on wear performance of the low contact stress total knee system.
PubMed: Effect of polymer molecular weight and addition of calcium stearate on response of MG63 osteoblast-like cells to UHMWPE particles.
PubMed: Precipitation and Solubility of Calcium Soaps in Basic Aqueous Media.
PubMed: Effect of magnesium stearate or calcium stearate as additives on dissolution profiles of diltiazem hydrochloride from press-coated tablets with hydroxypropylmethylcellulose acetate succinate in the outer shell.
PubMed: An in vitro investigation of the suitability of press-coated tablets with hydroxypropylmethylcellulose acetate succinate (HPMCAS) and hydrophobic additives in the outer shell for colon targeting.
PubMed: Possible explanation for the white band artifact seen in clinically retrieved polyethylene tibial components.
PubMed: Elemental and morphological identification of third-body particulate and calcium stearate inclusions in polyethylene components.
PubMed: Clinical wear of 63 ultrahigh molecular weight polyethylene acetabular components: effect of starting resin and forming method.
PubMed: Effect of molecular weight, calcium stearate, and sterilization methods on the wear of ultra high molecular weight polyethylene acetabular cups in a hip joint simulator.
PubMed: A comparison of sutures for adjustable strabismus surgery.
PubMed: A slow release calcium delivery system for the study of reparative dentine formation.
PubMed: Fourier transform infrared and Raman microspectroscopy of materials in tissue.
PubMed: The effect of modification of acrylic resins on controlled release and bioadhesion.
PubMed: Multiple emulsion-based systems carrying insulin: development and characterization.
PubMed: Prolonged release of rifampicin from multiple w/o/w emulsion systems.
PubMed: Composition and behavior of head membrane lipids of fresh and cryopreserved boar sperm.
PubMed: A slow release formulation for recombinant bovine interferon alpha I-1.
PubMed: Role of calcium ion in Schistosoma mansoni cercarial tail loss induced by unsaturated fatty acids.
PubMed: Protein adsorption--effect of external lubricants at the interface.
PubMed: Ruminal biohydrogenation of fatty acids from high-oleate sunflower seeds.
PubMed: [The atomic absorption determination of calcium, zinc, barium, lead and silver stearates in the air of a work area].
PubMed: Physiochemical interactions of praziquantel, oxamniquine and tablet excipients.
PubMed: Calpain activation is essential for membrane fusion of erythrocytes in the presence of exogenous Ca2+.
PubMed: [The cytotoxic action of metal stearates and its correlation with the toxicity for animals].
PubMed: Leaching of plasticizers from and surface characterization of PVC blood platelet bags.
PubMed: [Experimental data on the effects of lead, barium, silver, zinc and calcium stearates on the cardiovascular system].
PubMed: Restoration of the LH secretory response in desensitized gonadotropes.
PubMed: Gas chromatographic determination of calcium stearate in polyethylene food packaging sheets.
PubMed: Calpain-calpastatin and fusion. Fusibility of erythrocytes is determined by a protease-protease inhibitor [calpain-calpastatin] balance.
PubMed: Fusion of rat erythrocytes by membrane-mobility agent A2C depends on membrane proteolysis by a cytoplasmic calpain.
PubMed: Growth characteristics of selected fungi on polyvinyl chloride film.
PubMed: Effect of antagonists of calcium and phospholipase A on the cytopathogenicity of Entamoeba histolytica.
PubMed: Phospholipase A enzymes of Entamoeba histolytica: description and subcellular localization.
PubMed: Gangrene of the upper extremity following intra-arterial injection of drugs. A case report and review of the literature.
PubMed: Membrane-mobility agent-promoted fusion of erythrocytes: fusibility is correlated with attack by calcium-activated cytoplasmic proteases on membrane proteins.
PubMed: Adrenal and hepatic calcium stearate crystal deposits in dogs fed a thiamine-deficient diet.
PubMed: Tensile strengths and hardness of tablets.
PubMed: Physicochemical properties of magnesium salicylate.
PubMed: Studies on the metabolism of calcium stearoyl-2-lactylate in the rat, mouse, guinea-pig and man.
PubMed: Fusion of Dictyostelium cells with one another and with erythrocyte ghosts.
PubMed: Electrical conductance of directly compressible materials under pressure.
PubMed: Effect of microcrystalline cellulose on liquid penetration in and disintegration of directly compressed tablets.
PubMed: Effects of compression force, particle size, and lubricants on dissolution rate.
PubMed: Particle slippage and rearrangement during compression of pharmaceutical powders.
PubMed: The adhesion of film coatings to tablet surfaces--the effect of some direct compression excipients and lubricants.
PubMed: Comparative evaluation of tablet lubricants: effect of application method on tablet hardness and ejectability after compression.
PubMed: Comparative toxicity of metal stearates.
PubMed: [Residual moisture of a tableted binary system granulate].
PubMed: [Thin layer chromatographic examination of calcium and sodium stearoyllactylate among other emulsifying agents in foodstuff].
PubMed: [Toxicology of metal stearates, polymer stabilizers (a review of the literature)].
PubMed: Application of powder failure testing equipment in assessing effect on glidants on flowability of cohesive pharmaceutical powders.
PubMed: [Studies on packing-property of pharmaceutical powders. 3. Influence of calcium stearate content on compacting phenomenon of pharmaceutical powders (author's transl)].
PubMed: [Studies on packing-property of pharmaceutical powders. II. Compacting phenomenon of pharmaceutical powders in the course of mixing with calcium stearate].
PubMed: X-ray diffraction studies of the composition of gallstones from English and Australian patients.
PubMed: Properties, composition, and structure of stearic acid-stearate monolayers on alkaline earth solutions.
PubMed: Interactions of veratrum alkaloids, procaine, and calcium with monolayers of stearic acid and their implications for pharmacological action.
PubMed: Crystal forms of anhydrous calcium stearate derivable from calcium stearate monohydrate.
PubMed: Properties of systems of calcium stearate and cetane as deduced from X-ray diffraction patterns.
PubMed: Polymorphic transformations of calcium stearate and calcium stearate monohydrate.
PubMed: Lubricating properties of molecular layers of stearic acid and calcium stearate on metal surfaces.
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