EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes

fucoidan
sulfated fucans

Supplier Sponsors

CAS Number: 9072-19-9
FDA UNII: Search
Formula:unspecified
Category:food additive
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
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Google Patents:Search
US Patents:Search
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PubMed:Search
NCBI:Search
 FDA/DG SANTE Petitions, Reviews, Notices:
GRN 565 Fucoidan from Undaria pinnatifida View - notice PDF
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BOC Sciences
For experimental / research use only.
Fucoidan - Ascophyllum nodosum
Carbosynth
For experimental / research use only.
Fucoidan
Jiangyin Healthway
Fucoidan
New functional food ingredients
Jiangyin Healthway
Fucoidan
Layn Natural ingredients
Seaweed Extract Fucoidan 80%
Santa Cruz Biotechnology
For experimental / research use only.
Fucoidan
Sigma-Aldrich: Sigma
For experimental / research use only.
Fucoidan from Undaria pinnatifida ≥95%
sds
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
food additive
Recommendation for fucoidan usage levels up to:
 not for fragrance use.
 
Recommendation for fucoidan flavor usage levels up to:
 not for flavor use.
 
Safety References:
ClinicalTrials.gov:search
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
Chemidplus:0009072199
 
References:
Canada Domestic Sub. List:9072-19-9
Pubchem (sid):135350887
 
Other Information:
HMDB (The Human Metabolome Database):Search
FDA Listing of Food Additive Status:View
VCF-Online:VCF Volatile Compounds in Food
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 found in nature
 
Synonyms:
 fucan sulfate
 fucoidan from undaria pinnatifida
 fucoidin
 nutralga
 sulfated fucans
 

Articles:

PubMed:Effects of fucoidan on insulin stimulation and pancreatic protection via the cAMP signaling pathway in vivo and in vitro.
PubMed:Efficacy of Cistanche Tubulosa and Laminaria Japonica Extracts (MK-R7) Supplement in Preventing Patterned Hair Loss and Promoting Scalp Health.
PubMed:Seaweed polysaccharides (laminarin and fucoidan) as functional ingredients in pork meat: an evaluation of anti-oxidative potential, thermal stability and bioaccessibility.
PubMed:Functional components and medicinal properties of food: a review.
PubMed:Prophylactic administration of fucoidan represses cancer metastasis by inhibiting vascular endothelial growth factor (VEGF) and matrix metalloproteinases (MMPs) in Lewis tumor-bearing mice.
PubMed:Wakame (Undaria pinnatifida ) modulates hyperphosphatemia in a rat model of chronic renal failure.
PubMed:Structure and rheological characteristics of fucoidan from sea cucumber Apostichopus japonicus.
PubMed:Fucoidan exerts protective effects against diabetic nephropathy related to spontaneous diabetes through the NF-κB signaling pathway in vivo and in vitro.
PubMed:Fucoidan supplementation improves exercise performance and exhibits anti-fatigue action in mice.
PubMed:Characterisation of bovine serum albumin-fucoidan conjugates prepared via the Maillard reaction.
PubMed:Influence of level and duration of feeding polysaccharide (laminarin and fucoidan) extracts from brown seaweed (Laminaria digitata) on quality indices of fresh pork.
PubMed:Chitosan/fucoidan multilayer nanocapsules as a vehicle for controlled release of bioactive compounds.
PubMed:Dietary fucoidan of Acaudina molpadioides and its enzymatically degraded fragments could prevent intestinal mucositis induced by chemotherapy in mice.
PubMed:The beneficial properties of marine polysaccharides in alleviation of allergic responses.
PubMed:Fucoidan, a sulfated polysaccharide, inhibits osteoclast differentiation and function by modulating RANKL signaling.
PubMed:Pharmaceutical, cosmeceutical, and traditional applications of marine carbohydrates.
PubMed:Marine-derived polysaccharides for regulation of allergic responses.
PubMed:Molecular characterization and immunomodulatory activity of sulfated fucans from Agarum cribrosum.
PubMed:Anticancer effects of different seaweeds on human colon and breast cancers.
PubMed:Preparation and characterization of antioxidant nanoparticles composed of chitosan and fucoidan for antibiotics delivery.
PubMed:Anticancer effects of fucoidan.
PubMed:Fucoidans from marine algae as potential matrix metalloproteinase inhibitors.
PubMed:Fucoidan from the sea cucumber Acaudina molpadioides exhibits anti-adipogenic activity by modulating the Wnt/β-catenin pathway and down-regulating the SREBP-1c expression.
PubMed:Fucoidan inhibits the proliferation of human urinary bladder cancer T24 cells by blocking cell cycle progression and inducing apoptosis.
PubMed:Hepatoprotective effect of fucoidan isolated from the seaweed Turbinaria decurrens in ethanol intoxicated rats.
PubMed:Differential effects of fucoidans with low and high molecular weight on the viability and function of spleen cells.
PubMed:Water soluble sulfated-fucans with immune-enhancing properties from Ecklonia cava.
PubMed:Effect of fucoidan administration on insulin secretion and insulin resistance in overweight or obese adults.
PubMed:Fucans from a Tunisian brown seaweed Cystoseira barbata: structural characteristics and antioxidant activity.
PubMed:Protective effect of fucoidan against AAPH-induced oxidative stress in zebrafish model.
PubMed:Effect of seaweed-derived laminarin and fucoidan and zinc oxide on gut morphology, nutrient transporters, nutrient digestibility, growth performance and selected microbial populations in weaned pigs.
PubMed:Ultrasound effects on the degradation kinetics, structure, and antioxidant activity of sea cucumber fucoidan.
PubMed:Alpha-amylase and alpha-glucosidase inhibition is differentially modulated by fucoidan obtained from Fucus vesiculosus and Ascophyllum nodosum.
PubMed:Anti-Proliferation Potential and Content of Fucoidan Extracted from Sporophyll of New Zealand Undaria pinnatifida.
PubMed:AKT signaling is involved in fucoidan-induced inhibition of growth and migration of human bladder cancer cells.
PubMed:Purification of a fucoidan from kelp polysaccharide and its inhibitory kinetics for tyrosinase.
PubMed:Structure elucidation of fucoidan composed of a novel tetrafucose repeating unit from sea cucumber Thelenota ananas.
PubMed:Effect of the interaction of seaweed extracts containing laminarin and fucoidan with zinc oxide on the growth performance, digestibility and faecal characteristics of growing piglets.
PubMed:Structural study of fucoidan from sea cucumber Acaudina molpadioides: a fucoidan containing novel tetrafucose repeating unit.
PubMed:Pharmaceutical potential of a fucoidan-like sulphated polysaccharide isolated from Halodule pinifolia.
PubMed:The fucoidans from brown algae of Far-Eastern seas: anti-tumor activity and structure-function relationship.
PubMed:Effect of basic fibroblast growth factor released from chitosan-fucoidan nanoparticles on neurite extension.
PubMed:Hypoglycemic property of acidic polysaccharide extracted from Saccharina japonica and its potential mechanism.
PubMed:Fucoidan prevents high-fat diet-induced obesity in animals by suppression of fat accumulation.
PubMed:Effect of a brown seaweed (Laminaria digitata) extract containing laminarin and fucoidan on the quality and shelf-life of fresh and cooked minced pork patties.
PubMed:Enzymatic preparation and structural determination of oligosaccharides derived from sea cucumber (Acaudina molpadioides) fucoidan.
PubMed:Effect of dietary laminarin and fucoidan on selected microbiota, intestinal morphology and immune status of the newly weaned pig.
PubMed:Safety evaluation of excessive ingestion of mozuku fucoidan in human.
PubMed:In vitro antioxidant properties of crude extracts and compounds from brown algae.
PubMed:Effects of supplementing dietary laminarin and fucoidan on intestinal morphology and the immune gene expression in the weaned pig.
PubMed:Effect of supplementing different ratios of laminarin and fucoidan in the diet of the weanling piglet on performance, nutrient digestibility, and fecal scoring.
PubMed:The microbiological and immunomodulatory effects of spray-dried versus wet dietary supplementation of seaweed extract in the pig gastrointestinal tract.
PubMed:Modulation of platelet aggregation-related eicosanoid production by dietary F-fucoidan from brown alga Laminaria japonica in human subjects.
PubMed:Effects of oral administration of fucoidan extracted from Cladosiphon okamuranus on tumor growth and survival time in a tumor-bearing mouse model.
PubMed:Low molecular weight fucoidan ameliorating the chronic cisplatin-induced delayed gastrointestinal motility in rats.
PubMed:Turbinaria conoides (J. Agardh) sulfated polysaccharide protects rat's heart against myocardial injury.
PubMed:Molecular characteristics and anti-inflammatory activity of the fucoidan extracted from Ecklonia cava.
PubMed:Addition of seaweed (Laminaria digitata) extracts containing laminarin and fucoidan to porcine diets: influence on the quality and shelf-life of fresh pork.
PubMed:Fucoidan regulate blood glucose homeostasis in C57BL/KSJ m+/+db and C57BL/KSJ db/db mice.
PubMed:Sequence determination and anticoagulant and antithrombotic activities of a novel sulfated fucan isolated from the sea cucumber Isostichopus badionotus.
PubMed:Cytoprotective effects of fucoidan, an algae-derived polysaccharide on 5-fluorouracil-treated dendritic cells.
PubMed:Mobilization of mesenchymal stem cells by stromal cell-derived factor-1 released from chitosan/tripolyphosphate/fucoidan nanoparticles.
PubMed:Genotoxicity testing of low molecular weight fucoidan from brown seaweeds.
PubMed:Phlorotannins and fucoidans from marine macroalgae as matrix metalloproteinase inhibitory substances and their possible application as medicinal foods.
PubMed:Effect of maternal seaweed extract supplementation on suckling piglet growth, humoral immunity, selected microflora, and immune response after an ex vivo lipopolysaccharide challenge.
PubMed:A comparative study of antithrombotic and antiplatelet activities of different fucoidans from Laminaria japonica.
PubMed:Fucoidan, a sulfated polysaccharide from brown algae, against myocardial ischemia-reperfusion injury in rats via regulating the inflammation response.
PubMed:Anti-inflammatory effects of fucoidan through inhibition of NF-κB, MAPK and Akt activation in lipopolysaccharide-induced BV2 microglia cells.
PubMed:Antiproliferative activity of fucoidan was associated with the induction of apoptosis and autophagy in AGS human gastric cancer cells.
PubMed:Relationship between oversulfation and conformation of low and high molecular weight fucoidans and evaluation of their in vitro anticancer activity.
PubMed:Lymphoid neoplastic P388D1 cells express membrane protein candidates that discriminate among the C-terminal phylogenetic diversity in heat shock protein 70 sequences.
PubMed:Effect of dietary seaweed extracts and fish oil supplementation in sows on performance, intestinal microflora, intestinal morphology, volatile fatty acid concentrations and immune status of weaned pigs.
PubMed:Fucoidan present in brown algae induces apoptosis of human colon cancer cells.
PubMed:Structural characterization of laminaran and galactofucan extracted from the brown seaweed Saccharina longicruris.
PubMed:Toxicological evaluation of fucoidan from Undaria pinnatifidain vitro and in vivo.
PubMed:Effect of maternal fish oil and seaweed extract supplementation on colostrum and milk composition, humoral immune response, and performance of suckled piglets.
PubMed:The effect of dietary Laminaria-derived laminarin and fucoidan on nutrient digestibility, nitrogen utilisation, intestinal microflora and volatile fatty acid concentration in pigs.
PubMed:The effect of dietary laminarin and fucoidan in the diet of the weanling piglet on performance, selected faecal microbial populations and volatile fatty acid concentrations.
PubMed:Genotoxicity studies on fucoidan from Sporophyll of Undaria pinnatifida.
PubMed:Isolation and characterization of a sea cucumber fucoidan-utilizing marine bacterium.
PubMed:Different suppressive effects of fucoidan and lentinan on IL-8 mRNA expression in in vitro gut inflammation.
PubMed:Fucoidan induces apoptosis through activation of caspase-8 on human breast cancer MCF-7 cells.
PubMed:Evaluation and comparison of the antioxidative potency of various carbohydrates using different methods.
PubMed:Performance of weanling piglets offered low-, medium- or high-lactose diets supplemented with a seaweed extract from Laminaria spp.
PubMed:Inhibitory effects of Fucoidan in 3T3-L1 adipocyte differentiation.
PubMed:Toxicological evaluation of fucoidan from Cladosiphon okamuranus.
PubMed:Determination of physicochemical properties of sulphated fucans from sporophyll of Undaria pinnatifida using light scattering technique.
PubMed:Dietary fiber and antioxidant capacity in Fucus vesiculosus products.
PubMed:The effects of seaweed extract inclusion on gut morphology, selected intestinal microbiota, nutrient digestibility, volatile fatty acid concentrations and the immune status of the weaned pig.
PubMed:Fucoidan: structure and bioactivity.
PubMed:Effects of molecular weight and hydrolysis conditions on anticancer activity of fucoidans from sporophyll of Undaria pinnatifida.
PubMed:In vitro model to estimate gut inflammation using co-cultured Caco-2 and RAW264.7 cells.
PubMed:Inhibitory effects of fucoidan on activation of epidermal growth factor receptor and cell transformation in JB6 Cl41 cells.
PubMed:Effect of dietary fiber in edible seaweeds on the development of D-galactosamine-induced hepatopathy in rats.
PubMed:In vitro antioxidative activities of three marine oligosaccharides.
PubMed:Antioxidant activities of sulfated polysaccharides from brown and red seaweeds.
PubMed:Structural investigation of a fucoidan containing a fucose-free core from the brown seaweed, Hizikia fusiforme.
PubMed:Sulfated polysaccharides derived from dietary seaweeds increase the esterase activity of a lymphocyte tryptase, granzyme A.
PubMed:Immunomodulating activity of arabinogalactan and fucoidan in vitro.
PubMed:Toxicological evaluation of fucoidan extracted from Laminaria japonica in Wistar rats.
PubMed:Analysis of leukocyte rolling and migration--using inhibitors in the undisturbed microcirculation of the rat mesentery--on inflammatory stimulation.
PubMed:Purification and identification of a binding protein for pancreatic secretory trypsin inhibitor: a novel role of the inhibitor as an anti-granzyme A.
PubMed:Potential antioxidant capacity of sulfated polysaccharides from the edible marine brown seaweed Fucus vesiculosus.
PubMed:Anti-ulcer effects and biological activities of polysaccharides from marine algae.
PubMed:Characteristics of Mycoplasma hominis adhesion.
PubMed:Anticoagulant properties of a fucoïdan fraction.
PubMed:Adhesion of Bordetella pertussis to sulfatides and to the GalNAc beta 4Gal sequence found in glycosphingolipids.
 
Notes:
fucose-sulfate polymer found in brown algae.
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