nordazepam, 1088-11-5

Articles:

PubMed:Quantification of five compounds with heterogeneous physicochemical properties (morphine, 6-monoacetylmorphine, cyamemazine, meprobamate and caffeine) in 11 fluids and tissues, using automated solid-phase extraction and gas chromatography-tandem mass spectrometry.

PubMed:Urinary diazepam metabolite distribution in a chronic pain population.

PubMed:Direct determination of diazepam and its glucuronide metabolites in human whole blood by μElution solid-phase extraction and liquid chromatography-tandem mass spectrometry.

PubMed:Diazepam and its metabolites in the mothers' and newborns' hair as a biomarker of prenatal exposure.

PubMed:An air-tolerant approach to the carbonylative Suzuki-Miyaura coupling: applications in isotope labeling.

PubMed:Concentrations of drugs determined in blood samples collected from suspected drugged drivers in England and Wales.

PubMed:The potential of forensic analysis on human bones found in riverine environment.

PubMed:Evaluation of plasma diazepam and nordiazepam concentrations following administration of diazepam intravenously or via suppository per rectum in dogs.

PubMed:Blood drug concentrations of benzodiazepines correlate poorly with actual driving impairment.

PubMed:Sensitive UPLC-MS-MS assay for 21 benzodiazepine drugs and metabolites, zolpidem and zopiclone in serum or plasma.

PubMed:Concentrations of diazepam and nordiazepam in 1,000 blood samples from apprehended drivers--therapeutic use or abuse of anxiolytics?

PubMed:Muscle relaxants for pain management in rheumatoid arthritis.

PubMed:Combined occlusal and pharmacological therapy in the treatment of temporo-mandibular disorders.

PubMed:Gas chromatography-tandem mass spectrometry assay for the quantification of four benzodiazepines and citalopram in eleven postmortem rabbit fluids and tissues, with application to animal and human samples.

PubMed:Detection and validated quantification of 21 benzodiazepines and 3 "z-drugs" in human hair by LC-MS/MS.

PubMed:Pharmacokinetics of diazepam administered intramuscularly by autoinjector versus rectal gel in healthy subjects: a phase I, randomized, open-label, single-dose, crossover, single-centre study.

PubMed:Comparison by means of bispectral index score, between anxiolysis induced by diazepam and sedation induced by midazolam.

PubMed:Pharmacokinetics of the cytochrome P-450 substrates phenytoin, theophylline, and diazepam in healthy Greyhound dogs.

PubMed:Folie à deux: double case-report of shared delusions with a fatal outcome.

PubMed:Reduction of temazepam to diazepam and lorazepam to delorazepam during enzymatic hydrolysis.

PubMed:Diazepam pharmacokinetics after nasal drop and atomized nasal administration in dogs.

PubMed:Biotransformation of diazepam in a clinically relevant flat membrane bioreactor model using primary porcine hepatocytes.

PubMed:A novel reductive transformation of oxazepam to nordiazepam observed during enzymatic hydrolysis.

PubMed:Electronic properties of neuroleptics: ionization energies of benzodiazepines.

PubMed:Simultaneous determination and quantification of 12 benzodiazepines in serum or whole blood using UPLC/MS/MS.

PubMed:LC-MS/MS analysis of 13 benzodiazepines and metabolites in urine, serum, plasma, and meconium.

PubMed:Quantitation of benzodiazepines in blood and urine using gas chromatography-mass spectrometry (GC-MS).

PubMed:Measurement of benzodiazepines in urine by liquid chromatography-tandem mass spectrometry: confirmation of samples screened by immunoassay.

PubMed:Effects of organic solvents on the time-dependent inhibition of CYP3A4 by diazepam.

PubMed:Simultaneous analysis of diazepam and its metabolites in rat plasma and brain tissue by HPLC-UV and SPE.

PubMed:[Mechanisms of opioid-induced overdose: experimental approach to clinical concerns].

PubMed:Quantification of chlordesmethyldiazepam by liquid chromatography-tandem mass spectrometry: application to a cloxazolam bioequivalence study.

PubMed:Cardiac and peripheral blood similarities in the comparison of nordiazepam and bromazepam blood concentrations.

PubMed:Alleged breaches of "standards of medical care" in a patient overdose death possibly related to chronic opioid analgesic therapy, application of the controlled substances model guidelines: case report.

PubMed:Two compartment model of diazepam biotransformation in an organotypical culture of primary human hepatocytes.

PubMed:Determination of diazepam and its metabolites in human urine by liquid chromatography/tandem mass spectrometry using a hydrophilic polymer column.

PubMed:Fatal intoxication with milnacipran.

PubMed:New high-performance liquid chromatographic method for serum analysis of oxazepam: application to bioequivalence and pharmacokinetic study.

PubMed:Fatal intoxication with labetalol (Trandate).

PubMed:Thiodicarb and methomyl tissue distribution in a fatal multiple compounds poisoning.

PubMed:Bioavailability and dose proportionality of intramuscular diazepam administered by autoinjector.

PubMed:Massive intoxication involving unusual high concentration of amitriptyline.

PubMed:Voriconazole and fluconazole increase the exposure to oral diazepam.

PubMed:Concentrations of scheduled prescription drugs in blood of impaired drivers: considerations for interpreting the results.

PubMed:LC-MS-MS analysis of 2,4-dinitrophenol and its phase I and II metabolites in a case of fatal poisoning.

PubMed:Highlights on new food research.

PubMed:A sensitive and selective method for the detection of diazepam and its main metabolites in urine by gas chromatography-tandem mass spectrometry.

PubMed:Optimized determination of lorazepam in human serum by extraction and high-performance liquid chromatographic analysis.

PubMed:Medicolegal aspects of tetrazepam metabolism.

PubMed:Liquid chromatographic-electrospray ionization mass spectrometric quantitative analysis of buprenorphine, norbuprenorphine, nordiazepam and oxazepam in rat plasma.

PubMed:Fast in vivo microextraction: a new tool for clinical analysis.

PubMed:Date-rape drugs scene in Poland.

PubMed:Quantification of benzodiazepines in whole blood and serum.

PubMed:Papain: a novel urine adulterant.

PubMed:Hair analysis by liquid chromatography-tandem mass spectrometry in toxicological investigation of drug-facilitated crimes: report of 128 cases over the period June 2003-May 2004 in metropolitan Paris.

PubMed:Fast, simple, and validated gas chromatographic-mass spectrometric assay for quantification of drugs relevant to diagnosis of brain death in human blood plasma samples.

PubMed:Development and validation of a liquid chromatographic/electrospray ionization mass spectrometric method for the quantitation of prazepam and its main metabolites in human plasma.

PubMed:High concentrations of diazepam and nordiazepam in blood of impaired drivers: association with age, gender and spectrum of other drugs present.

PubMed:Screening, library-assisted identification and validated quantification of 23 benzodiazepines, flumazenil, zaleplone, zolpidem and zopiclone in plasma by liquid chromatography/mass spectrometry with atmospheric pressure chemical ionization.

PubMed:Combined sedation with oral chlordemethyldiazepam and midazolam by nasal route in third molar surgery.

PubMed:Distribution of diazepam and nordiazepam between plasma and whole blood and the influence of hematocrit.

PubMed:Toxicological data and growth characteristics of single post-feeding larvae and puparia of Calliphora vicina (Diptera: Calliphoridae) obtained from a controlled nordiazepam study.

PubMed:Coexistence and concentrations of ethanol and diazepam in postmortem blood specimens: risk for enhanced toxicity?

PubMed:Buprenorphine in drug-facilitated sexual abuse: a fatal case involving a 14-year-old boy.

PubMed:Ximelagatran, an oral direct thrombin inhibitor, has a low potential for cytochrome P450-mediated drug-drug interactions.

PubMed:Effects of diazepam and its metabolites on nocturnal melatonin secretion in the rat pineal and Harderian glands. A comparative in vivo and in vitro study.

PubMed:Evaluation of the novel antiepileptic drug, AWD 131-138, for benzodiazepine-like discriminative stimulus and reinforcing effects in squirrel monkeys.

PubMed:Fatal accident caused by isoflurane abuse.

PubMed:Interpretations of the TDxFLx calibration data of the abused drugs.

PubMed:Quantitation using GC-TOF-MS: example of bromazepam.

PubMed:Bio-compatible in-tube solid-phase microextraction capillary for the direct extraction and high-performance liquid chromatographic determination of drugs in human serum.

PubMed:Alcohol and benzodiazepines in fatal poisonings.

PubMed:SPME-LC with UV detection to study delorazepam-serum albumin interactions.

PubMed:Sensitive method for the detection of 22 benzodiazepines by gas chromatography-ion trap tandem mass spectrometry.

PubMed:[Fatal outcome of poisoning with the benzodiazepines flunitrazepam and diazepam].

PubMed:Determination of delorazepam in urine by solid-phase microextraction coupled to high performance liquid chromatography.

PubMed:Direct determination of benzodiazepines in biological fluids by restricted-access solid-phase microextraction.

PubMed:Binding of [3H]CB 34, a selective ligand for peripheral benzodiazepine receptors, to rat brain membranes.

PubMed:Direct LC analysis of five benzodiazepines in human urine and plasma using an ADS restricted access extraction column.

PubMed:A contemporaneous finding of fenproporex in a polydrug suicide.

PubMed:The simultaneous determination of diazepam and its three metabolites in dog plasma by high-performance liquid chromatography with mass spectroscopy detection.

PubMed:Urinary excretion of diazepam metabolites in healthy volunteers and drug users.

PubMed:Diazepam poisoning with one-month monitoring of diazepam and nordiazepam blood levels.

PubMed:Screening, identification and quantitation of benzodiazepines in serum by solid phase extraction on a cyanopropyl phase using high performance liquid chromatography and photodiode array detection.

PubMed:Liquid-phase microextraction as a sample preparation technique prior to capillary gas chromatographic-determination of benzodiazepines in biological matrices.

PubMed:Fatal intoxication with melperone.

PubMed:A modified simple and rapid reversed phase liquid chromatographic method for quantification of diazepam and nordiazepam in plasma.

PubMed:Influence of bleaching on stability of benzodiazepines in hair.

PubMed:Benzodiazepines and postoperative cognitive dysfunction in the elderly. ISPOCD Group. International Study of Postoperative Cognitive Dysfunction.

PubMed:Prolonged sedation requiring mechanical ventilation and continuous flumazenil infusion after routine doses of clorazepam for alcohol withdrawal syndrome.

PubMed:Effect of the gene dosage of CgammaP2C19 on diazepam metabolism in Chinese subjects.

PubMed:Effect of dipotassium clorazepate on amygdaloid-kindling and comparison between amygdaloid- and hippocampal-kindled seizures in rats.

PubMed:Distribution of topiramate in a medical examiner's case.

PubMed:Sigmoidal kinetic model for two co-operative substrate-binding sites in a cytochrome P450 3A4 active site: an example of the metabolism of diazepam and its derivatives.

PubMed:The urinary elimination profiles of diazepam and its metabolites, nordiazepam, temazepam, and oxazepam, in the equine after a 10-mg intramuscular dose.

PubMed:Determination of benzodiazepines in human urine and plasma with solvent modified solid phase micro extraction and gas chromatography; rationalisation of method development using experimental design strategies.

PubMed:[Possibilities for toxicologic evidence in adipocere formation and postmortem interval of several years].

PubMed:Benzodiazepines: toxic serum concentrations in positive enzyme immunoassay responses.

PubMed:Rapid and simple chromatographic method for the determination of diazepam and its major metabolites in human plasma and urine.

PubMed:Peripheral benzodiazepine receptor messenger RNA is decreased in lymphocytes of generalized anxiety disorder patients.

PubMed:The effect of chronic benzodiazepines exposure on body weight in rats.

PubMed:Role of cDNA-expressed human cytochromes P450 in the metabolism of diazepam.

PubMed:Pilot investigation of thyrotropin-releasing hormone-induced thyrotropin and prolactin release in anxious patients treated with diazepam.

PubMed:Comparison of single- and repeated-dose pharmacokinetics of diazepam.

PubMed:Benzodiazepine-like compounds in the plasma of patients with fulminant hepatic failure.

PubMed:Naltrexone effects on diazepam intoxication and pharmacokinetics in humans.

PubMed:Diagnostic performance of the EMIT-tox benzodiazepine immunoassay, FPIA serum benzodiazepine immunoassay, and radioreceptor assay in suspected acute poisoning.

PubMed:Application of microdialysis to study the in vitro metabolism of drugs in liver microsomes.

PubMed:A fatality due to moclobemide.

PubMed:Age-related changes in the pharmacokinetic disposition of diazepam in foals.

PubMed:Paroxetine efficacy in the treatment of generalized anxiety disorder.

PubMed:Detection of benzodiazepines and other psychotropic drugs in human hair by GC/MS.

PubMed:Abnormal ventricular repolarization mimicking myocardial infarction after heterocyclic antidepressant overdose.

PubMed:Effect of sertraline on the pharmacokinetics and protein binding of diazepam in healthy volunteers.

PubMed:Benzodiazepine misuse by drug addicts.

PubMed:Evidence against oppositional and pharmacokinetic mechanisms of tolerance to diazepam's sedative effects.

PubMed:Automation of toxicological screenings on a Hewlett Packard Chemstation GC-MS system.

PubMed:Extraction of selected drugs from serum using microwave irradiation.

PubMed:Assessment of diazepam loading dose therapy of delirium tremens.

PubMed:Reduction of oxazepam to desmethyldiazepam by human intestinal bacteria.

PubMed:Hair analysis for nordiazepam and oxazepam by gas chromatography--negative-ion chemical ionization mass spectrometry.

PubMed:[Benzodiazepines in geriatrics--a case report on prolonged action].

PubMed:[Detection of nordiazepam in the hair of drug addicts].

PubMed:Lymphatic bioavailability of diazepam and desmethyldiazepam in the rat.

PubMed:[Determination of diazepam concentration in maternal and fetal serum after intravenous administration during active phase of labor and its effects on neonates].

PubMed:Absorption of diazepam after its rectal administration in dogs.

PubMed:Flumazenil, diazepam, nordiazepam and oxazepam interactions on plasma protein binding.

PubMed:Comparison of the interaction potential of a new proton pump inhibitor, E3810, versus omeprazole with diazepam in extensive and poor metabolizers of S-mephenytoin 4'-hydroxylation.

PubMed:Interethnic difference in omeprazole's inhibition of diazepam metabolism.

PubMed:Flunitrazepam and nordiazepam slowly released from silastic capsules induce physical dependence in rat.

PubMed:Development and preliminary application of high-performance liquid chromatographic assay of urinary metabolites of diazepam in humans.

PubMed:Acid-base equilibria of 1,4-benzodiazepine 4-oxides by spectrophotometry.

PubMed:Premedication with chlordemethyldiazepam and anxiolytic effect of diazepeam in implantology.

PubMed:[Determination of N-demethyldiazepam and its metabolite oxazepam in plasma by HPLC and their pharmacokinetics in rats].

PubMed:[Comparison of the effectiveness of orally administered clorazepate dipotassium and nordiazepam on preoperative anxiety].

PubMed:Behavioral and metabolic consequences of neonatal exposure to diazepam in rat pups.

PubMed:Effects of liver disease on the pharmacokinetics of intravenous and oral chlordesmethyldiazepam.

PubMed:Lack of low Km diazepam N-demethylase in livers of poor metabolizers for S-mephenytoin 4'-hydroxylation.

PubMed:Inhibition of diazepam metabolism by fluvoxamine: a pharmacokinetic study in normal volunteers.

PubMed:Metabolic and subjective responses to oral diazepam and midazolam.

PubMed:Diazepam metabolism by human liver microsomes is mediated by both S-mephenytoin hydroxylase and CYP3A isoforms.

PubMed:[Electroencephalographic demonstration of central nervous system effects of different premedication regimens].

PubMed:[Preanesthesia in elderly patients undergoing subarachnoid anesthesia: chlordesmethyldiazepam versus diazepam].

PubMed:Radioiodinated nordiazepam analog for in vivo assessment of benzodiazepine receptors by single photon emission tomography.

PubMed:Relationship between plasma benzodiazepine receptor ligand concentrations and severity of hepatic encephalopathy.

PubMed:Mesolimbic dopamine turnover effects of benzodiazepines do not correlate with sedative and muscle-relaxant potencies.

PubMed:Pharmacokinetic differences of desmethyldiazepam in three outbred Wistar strains related to differences in liver enzyme activities.

PubMed:Immunoassay detection of nordiazepam, triazolam, lorazepam, and alprazolam in blood.

PubMed:Analysis of oxazepam in urine using solid-phase extraction and high-performance liquid chromatography with fluorescence detection by post-column derivatization.

PubMed:Determination of plasma diazepam and desmethyldiazepam by solid-phase extraction and reversed-phase high-performance liquid chromatography.

PubMed:Effects of a 44-day administration of phenobarbital on disposition of clorazepate in dogs.

PubMed:Kinetics of sequential metabolism. II. Formation and metabolism of nordiazepam and oxazepam from diazepam in the perfused murine liver.

PubMed:Kinetics of sequential metabolism. I. Formation and metabolism of oxazepam from nordiazepam and temazepam in the perfused murine liver.

PubMed:Pharmacokinetics of nordiazepam in physical dependence and precipitated abstinence in dogs.

PubMed:Solid-phase extraction of 1,4-benzodiazepines from biological fluids.

PubMed:Inhibitory effect of diltiazem on diazepam metabolism in the mouse hepatic microsomes.

PubMed:Subjective and behavioral effects of diazepam depend on its rate of onset.

PubMed:Studies of "endogenous" benzodiazepine in human hepatic encephalopathy.

PubMed:Studies on the excretion of diazepam and nordazepam into milk for the prediction of milk-to-plasma drug concentration ratios.

PubMed:Quantitation by gas chromatography with selected-ion monitoring mass spectrometry of "natural" diazepam, N-desmethyldiazepam and oxazepam in normal human serum.

PubMed:Incidence of S-mephenytoin hydroxylation deficiency in a Korean population and the interphenotypic differences in diazepam pharmacokinetics.

PubMed:Determination of nonderivatized para-hydroxylated metabolites of diazepam in biological fluids with a GC Megabore column system.

PubMed:Diazepam metabolism by rat and human liver in vitro: inhibition by mephenytoin.

PubMed:The effects of felodipine on the pharmacokinetics of diazepam.

PubMed:Comparative metabolism of clinically important precursors of N-desmethyldiazepam using phenobarbitone-pretreated rat liver microsomes.

PubMed:Benzodiazepine metabolism in ethanol-treated male rats: use of pair-fed and age-matched controls.

PubMed:Niaprazine vs chlordesmethyldiazepam in sleep disturbances in pediatric outpatients.

PubMed:Effect of benzodiazepines on tryptophan binding to rat hepatic nuclei.

PubMed:Serum disposition of oral clorazepate from regular-release and sustained-delivery tablets in dogs.

PubMed:[Monitoring of diazepam treatment: comparison of the results of gas chromatography and radioreceptor methods].

PubMed:Pharmacokinetics of diazepam intramuscularly administered to rhesus monkeys.

PubMed:Chronic administration of and dependence on halazepam, diazepam, and nordiazepam in the dog.

PubMed:Elevated brain concentrations of 1,4-benzodiazepines in fulminant hepatic failure.

PubMed:Effect of orally administered misoprostol and cimetidine on the steady state pharmacokinetics of diazepam and nordiazepam in human volunteers.

PubMed:Amnestic effects of intravenous diazepam in healthy young men.

PubMed:Differences in the duration of sedative and anxiolytic effects of desmethyldiazepam in two outbred Wistar strains.

PubMed:Determination of diazepam and nordazepam in milk and plasma in the presence of oxazepam and temazepam.

PubMed:Characterization by saturation studies of the in vivo binding of [3H]flunitrazepam in mouse brain.

PubMed:Pharmacokinetic profiles of prazepam and 14C-prazepam in rat.

PubMed:Pharmacokinetics of intravenous and oral chlordesmethyldiazepam in patients on regular haemodialysis.

PubMed:Distribution of diazepam, nordiazepam, and oxazepam between brain extraneuronal space, brain tissue, plasma, and cerebrospinal fluid in diazepam and nordiazepam dependent dogs.

PubMed:Disposition of clorazepate in dogs after single- and multiple-dose oral administration.

PubMed:A death due to self-administered fentanyl.

PubMed:Benzodiazepine-induced antagonism of opioid antinociception may be abolished by spinalization or blockade of the benzodiazepine receptor.

PubMed:Ciprofloxacin does not impair the elimination of diazepam in humans.

PubMed:Depressive stupor and chlordesmethyldiazepam.

PubMed:[Antagonism with flumazenil of sedation by benzodiazepine during loco-regional anesthesia].

PubMed:Liquid chromatographic assay and pharmacokinetics of halazepam and its metabolite in humans.

PubMed:Diazepam loading in alcohol withdrawal: clinical pharmacokinetics.

PubMed:Cytochrome P450IIIA enzymes in rat liver microsomes: involvement in C3-hydroxylation of diazepam and nordazepam but not N-dealkylation of diazepam and temazepam.

PubMed:Depressive stupor treated with intramuscular chlordesmethyldiazepam.

PubMed:Effect of omeprazole and cimetidine on plasma diazepam levels.

PubMed:Effects of single doses of alprazolam and diazepam, alone and in combination with ethanol, on psychomotor and cognitive performance and on autonomic nervous system reactivity in healthy volunteers.

PubMed:Effect of chronic oral delorazepam on in vitro and in vivo hepatic drug-metabolizing enzyme activities in the rat.

PubMed:Excretion of diazepam and its metabolites in human milk during withdrawal from combination high dose diazepam and oxazepam.

PubMed:Effect of omeprazole treatment on diazepam plasma levels in slow versus normal rapid metabolizers of omeprazole.

PubMed:Determination of pharmacodynamics of diazepam by quantitative pharmaco-EEG.

PubMed:Bioinequivalence of a generic brand of diazepam.

PubMed:A large-sample study of diazepam pharmacokinetics.

PubMed:[Control of the side effects of ketamine: chlordemethyldiazepam vs diazepam in pre-anesthesia].

PubMed:In vitro drug metabolism and pharmacokinetics of diazepam in cynomolgus monkey hepatocytes during culture for six days.

PubMed:Effect of the benzodiazepines diazepam, des-N-methyldiazepam and midazolam on corticosteroid biosynthesis in bovine adrenocortical cells in vitro; location of site of action.

PubMed:Detection of desmethyldiazepam and diazepam in brain of different species and plants.

PubMed:Physical dependence on diazepam in the dog: precipitation of different abstinence syndromes by the benzodiazepine receptor antagonists Ro 15-1788 and ZK 93426.

PubMed:Importance of genetic factors in the regulation of diazepam metabolism: relationship to S-mephenytoin, but not debrisoquin, hydroxylation phenotype.

PubMed:A rapid HPLC procedure for the simultaneous determination of chloroquine, monodesethylchloroquine, diazepam, and nordiazepam in blood.

PubMed:Efficacy of flumazenil in COPD patient with therapeutic diazepam levels.

PubMed:[Chlordesmethyldiazepam and prolactinemia during surgical stress].

PubMed:Placental transfer and distribution of pinazepam and its metabolite N-desmethyldiazepam in the maternal and fetal rabbit: effect of the stage of gestation.

PubMed:Double-blind placebo cross-over study of long-acting (chlordesmethyldiazepam) versus short-acting (lorazepam) benzodiazepines in generalized anxiety disorders.

PubMed:Toxicity in a case of acute and massive overdose of chlordiazepoxide and its correlation to blood concentration.

PubMed:Radioreceptor assay of clonazepam and diazepam in blood for therapeutic drug monitoring.

PubMed:Benzodiazepines: are they of natural origin?

PubMed:Clorazepate, correlation between metabolism and anticonvulsant activity.

PubMed:[A ketamine-chlordemethyldiazepam combination in celioscopy].

PubMed:Studies of cyclodextrin inclusion complexes: II--Inclusion complexes between alpha-cyclodextrin and N-desmethyldiazepam and chlordiazepoxide.

PubMed:Sensitive determination of diazepam and N-desmethyldiazepam in human material using capillary gas chromatography-mass spectrometry.

PubMed:[Screening of the new benzodiazepine derivative, pinazepan, and its major metabolites].

PubMed:Comparative single-dose kinetics and dynamics of lorazepam, alprazolam, prazepam, and placebo.

PubMed:[Use of a chlordemethyldiazepam-fentanyl combination in invasive neuroradiologic examinations].

PubMed:Desmethyldiazepam pharmacokinetics: studies following intravenous and oral desmethyldiazepam, oral clorazepate, and intravenous diazepam.

PubMed:Metabolism of diazepam in vitro by human liver. Independent variability of N-demethylation and C3-hydroxylation.

PubMed:Kinetics of drug action in disease states. XXV. Effect of experimental hypovolemia on the pharmacodynamics and pharmacokinetics of desmethyldiazepam.

PubMed:Effects of HOE 760 (histamine H2-receptor antagonist) on diazepam pharmacokinetics.

PubMed:[Potentiating drugs in postoperative pain control with opiates for patient controlled analgesia].

PubMed:Precipitation of abstinence in nordiazepam- and diazepam-dependent dogs.

PubMed:The effect of fluoxetine on the pharmacokinetics and psychomotor responses of diazepam.

PubMed:Effect of food on absorption of chlordemethyldiazepam.

PubMed:Kinetics of drug action in disease states. XXIV. Pharmacodynamics of diazepam and its active metabolites in rats.

PubMed:Endogenous benzodiazepines in brain: right or wrong?

PubMed:Improved method for the determination of diazepam and N-desmethyldiazepam in plasma using capillary gas chromatography and nitrogen-phosphorus detection.

PubMed:[Effects of chlordemethyldiazepam on blood cortisol during surgical stress].

PubMed:Pharmacokinetics and bioavailability of intravenous and oral chlordesmethyldiazepam in humans.

PubMed:Comparison of sublingual and oral prazepam in normal subjects. II. Pharmacokinetic and pharmacodynamic data.

PubMed:Imipramine treatment alters the pharmacokinetics and pharmacodynamics of diazepam.

PubMed:Identification and differentiation of benzodiazepines and their metabolites in urine by computerized gas chromatography-mass spectrometry.

PubMed:Simultaneous determination of diazepam and its active metabolites in rat serum, brain and cerebrospinal fluid by high-performance liquid chromatography.

PubMed:Analysis of chlorodesmethyldiazepam and its metabolites in plasma and urine.

PubMed:The effect of diazepam on nociception in mice.

PubMed:Placental and blood-CSF transfer of orally administered diazepam in the same person.

PubMed:Validation of a radioreceptor assay technique for monitoring pharmacological active material during intensive diazepam tetanus therapy.

PubMed:Effects of propranolol, atenolol, and chlordesmethyldiazepam on response to mental stress in patients with recent myocardial infarction.

PubMed:Diazepam and desmethyldiazepam differ in their affinities and efficacies at 'central' and 'peripheral' benzodiazepine receptors.

PubMed:Microsample determination of diazepam and its three metabolites in serum by reversed-phase high-performance liquid chromatography.

PubMed:[Premedication for endoscopic examinations with intravenous administration of chlordesmethyldiazepam. A controlled double-blind study with diazepam and placebo].

PubMed:Nocturnal doses of ranitidine and nizatidine do not affect the disposition of diazepam.

PubMed:Apparent lesser physical dependence potential of nor-diazepam compared to diazepam in the rat.

PubMed:Differences in diazepam pharmacokinetics in Chinese and white Caucasians--relation to body lipid stores.

PubMed:Diazepam and N-desmethyldiazepam are found in rat brain and adrenal and may be of plant origin.

PubMed:[Chlordesmethyldiazepam as an anesthesia-inducing agent: time of loss of consciousness. Statistical analysis in man].

PubMed:Purification of a benzodiazepine from bovine brain and detection of benzodiazepine-like immunoreactivity in human brain.

PubMed:Influence of propranolol coadministration or cigarette smoking on the kinetics of desmethyldiazepam following intravenous clorazepate.

PubMed:Diazepam and methadone blood levels following concurrent administration of diazepam and methadone.

PubMed:[Determination of diazepam and its metabolites in the blood by microcolumn high-performance liquid chromatography].

PubMed:Serum concentrations of diazepam and its metabolite desmethyldiazepam in epileptic patients after chronic diazepam treatment.

PubMed:Potencies of diazepam metabolites in rats trained to discriminate diazepam.

PubMed:Pharmacokinetics of chlordesmethyldiazepam after single-dose oral administration in humans.

PubMed:P-450 activity in monolayer cultures of hepatocytes seeded in polystyrene tissue culture dishes.

PubMed:[Epilepsy induced by penicillin in rabbits: comparative study of the anticonvulsant effects of diazepam and chlordesmethyldiazepam].

PubMed:The effect of diazepam on indices of 5-HT function in man.

PubMed:Aging: changes in distribution of diazepam and metabolites in the rat.

PubMed:Interaction of diazepam with famotidine and cimetidine, two H2-receptor antagonists.

PubMed:The pharmacological profile of chlordesmethyldiazepam and other benzodiazepines.

PubMed:Acute tolerance to diazepam in mice: pharmacokinetic considerations.

PubMed:Premedication with oral and rectal diazepam.

PubMed:Screening and quantification of hypnotic sedatives in serum by capillary gas chromatography with a nitrogen-phosphorus detector, and confirmation by capillary gas chromatography-mass spectrometry.

PubMed:Diazepam metabolism in the guinea pig materno-fetal model: effects of cigarette smoke.

PubMed:The pharmacokinetics of diazepam and desmethyldiazepam in rat brain and plasma.

PubMed:Preliminary study of the pharmacokinetics of desmethyldiazepam administered as drops or tablets.

PubMed:Age-related multiple-dose pharmacokinetics and anxiolytic effects of delorazepam (chlordesmethyldiazepam).

PubMed:Disruption of schedule-controlled behavior by Ro 15-1788 one day after acute treatment with benzodiazepines.

PubMed:Omeprazole inhibits oxidative drug metabolism. Studies with diazepam and phenytoin in vivo and 7-ethoxycoumarin in vitro.

PubMed:[Effects of intravenous administration of chlordesmethyldiazepam on paroxysmal intercritical activity in various electroclinical forms of infantile epilepsy].

PubMed:Tissue distribution of diazepam and its metabolite desmethyldiazepam: a human autopsy study.

PubMed:N-desmethyldiazepam physical dependence in dogs.

PubMed:Development of tolerance to the anticonvulsant effect of diazepam in amygdala-kindled rats.

PubMed:Discriminative-stimulus effects of midazolam in squirrel monkeys: comparison with other drugs and antagonism by Ro 15-1788.

PubMed:Severe withdrawal syndrome after substitution of a short-acting benzodiazepine for a long-acting benzodiazepine.

PubMed:Liquid-chromatographic assay of diazepam and its major metabolites in serum, and application to pharmacokinetic study of high doses of diazepam in schizophrenics.

PubMed:[Efficacy and kinetics of chlorazepate administered to anxious patients in a single daily dose].

PubMed:Responsiveness to oral diazepam in the elderly: relationship to total and free plasma concentrations.

PubMed:Effects of caffeine and chlor-desmethyldiazepam on fighting behavior of mice with different reactivity baselines.

PubMed:[Effect of sodium valproate on brain levels of diazepam and N-desmethyldiazepam in the rat].

PubMed:Effect of clorazepate in spasticity and rigidity: a quantitative study of reflexes and plasma concentrations.

PubMed:Plasma concentrations of diazepam and N-desmethyldiazepam in Asian children after an intravenous or rectal dose of diazepam.

PubMed:Long-lasting anticonvulsant effects of diazepam in different mouse strains: correlations with brain concentrations and receptor occupancy.

PubMed:Diazepam and desmethyldiazepam in breast milk.

PubMed:Inhibition of diazepam metabolism in microsomal- and perfused liver preparations of the rat by desmethyldiazepam, N-methyloxazepam and oxazepam.

PubMed:Implications of dosing tricyclic antidepressants and benzodiazepines in geriatrics.

PubMed:Withdrawal responses to abrupt discontinuation of desmethyldiazepam.

PubMed:Diazepam tapering in detoxification for high-dose benzodiazepine abuse.

PubMed:Propranolol interactions with diazepam, lorazepam, and alprazolam.

PubMed:In vitro interaction of diazepam and oxazepam with pancuronium and suxamethonium.

PubMed:Comparative single-dose kinetics of oxazolam, prazepam, and clorazepate: three precursors of desmethyldiazepam.

PubMed:Plasma concentrations and clinical effects after single oral doses of prazepam, clorazepate, and diazepam.

PubMed:Development of tolerance to the anticonvulsant effect of diazepam in dogs.

PubMed:Value of serum diazepam and nordiazepam measurements in anxious patients.

PubMed:Clinical importance of the interaction of diazepam and cimetidine.

PubMed:Multiple-dose halazepam kinetics.

PubMed:Diazepam and desmethyldiazepam plasma concentrations in chronic anxious outpatients.

PubMed:Pharmacokinetics of diazepam and nordiazepam in the cat.

PubMed:Cimetidine interaction with dipotassium clorazepate disposition in the anesthetized dog.

PubMed:The contribution of the active metabolites to the tolerance developing to diazepam in man: relationship to bioassayed serum benzodiazepine levels.

PubMed:Elimination kinetics and symptomatology of diazepam withdrawal in abusers.

PubMed:Subcellular distribution of pinazepam and its metabolite N-desmethyldiazepam in rat liver.

PubMed:Dose-response analysis of the behavioral effects of diazepam: II. Psychomotor performance, cognition and mood.

PubMed:Drowsiness sedation levels in anxious neurotic outpatients.

PubMed:Decreased serum protein binding of diazepam and its major metabolite in the neonate during the first postnatal week relate to increased free fatty acid levels.

PubMed:Antiepileptic effect and serum levels of clorazepate on children with refractory seizures.

PubMed:Placental transfer of pinazepam and its metabolite N-desmethyldiazepam in women at term.

PubMed:[Pharmacokinetics and metabolite pattern of tetrazepam and chlordesmethyldiazepam].

PubMed:Diazepam/beta-adrenoceptor antagonist interactions.

PubMed:Clorazepate dipotassium and diazepam in renal insufficiency: serum concentrations and protein binding of diazepam and desmethyldiazepam.

PubMed:Pharmacokinetics of benzodiazepines: metabolic pathways and plasma level profiles.

PubMed:Diazepam: prediction of pharmacodynamics from pharmacokinetics.

PubMed:Pharmacokinetic model for diazepam and its major metabolite desmethyldiazepam following diazepam administration.

PubMed:Radioimmunoassay for determination of prazepam and its metabolites.

PubMed:Prolonged accumulation of diazepam in obesity.

PubMed:Differences in in vitro binding of diazepam and N-desmethyldiazepam to maternal and fetal plasma proteins at birth: relation to free fatty acid concentration and other parameters.

PubMed:Pharmacokinetics of benzodiazepines and psychostimulants in children.

PubMed:Disposition, distribution, plasma protein binding and biliary excretion of pinazepam after i.p. administration to rat.

PubMed:[Use of chlordemethyldiazepam in pediatric preanesthesia].

PubMed:Identification of some interferences in the analysis of clorazepate.

PubMed:High-performance liquid chromatography determination of dipotassium clorazepate and its major metabolite nordiazepam in plasma.

PubMed:Psychomotor effects of diazepam in anxious patients and healthy volunteers.

PubMed:Steady state plasma concentration profiles and therapeutic response in anxious-depressed outpatients after administration of a chlordiazepoxide-amitriptyline combination.

PubMed:Repeated diazepam dosing in cirrhotic patients: cumulation and sedation.

PubMed:[Benzodiazepines: significance of kinetics for therapy].

PubMed:Diazepam kinetics in patients with severe burns.

PubMed:Serum protein binding of diazepam, desmethyldiazepam, furosemide, indomethacin, warfarin, and phenobarbital in human fetus, mother, and newborn infant.

PubMed:Multiple-dose pharmacokinetics of diazepam following once-daily administration of a controlled-release capsule.

PubMed:Metabolic and pharmacological studies with N-methyl-N'-methyl-2'-allyl-2-benzoyl-4-chloro-glycinanilide (F 1797).

PubMed:Halazepam as a precursor of desmethyldiazepam: quantitation by electron-capture gas-liquid chromatography.

PubMed:[Intraerythrocyte penetration of diazepam and its 2 principal metabolites].

PubMed:The role of buffer composition during equilibrium dialysis in determining concentrations of free diazepam in serum.

PubMed:Benzodiazepine kinetics: implications for therapeutics and pharmacogeriatrics.

PubMed:Blood concentrations of diazepam and its metabolites in children and neonates with tetanus.

PubMed:Pharmacokinetics of chlorazepate after intravenous and intramuscular administration.

PubMed:Correlation of the bioavailability of diazepam from uncoated tablets in beagle dogs with its dissolution rate and bioavailability in humans.

PubMed:Determination of peptidoaminobenzophenone (2-o-chlorobenzoyl-4-chloro-N-methyl-N'-glycylglycinanilide) and its metabolites in human plasma by glass capillary gas chromatography negative ion chemical ionization mass spectrometry--1.

PubMed:Chronic diazepam treatment in psychiatric outpatients.

PubMed:Cimetidine impairs clearance of antipyrine and desmethyldiazepam in the elderly.

PubMed:[Prevention and therapy of delirium tremens with tiapride and chlordesmethyldiazepam].

PubMed:New anxiolytics: are they really new?

PubMed:Value of a single night-time dose of potassium clorazepate in anxiety: a controlled trial comparison with diazepam.

PubMed:Prolongation of drug half-life due to obesity: studies of desmethyldiazepam (clorazepate).

PubMed:Kinetics of high-dose i.v. diazepam.

PubMed:Does ethyl-beta-carboline-3-carboxylate interact with mouse brain benzodiazepine receptors in vivo?

PubMed:Desmethyldiazepam kinetics after intravenous, intramuscular, and oral administration of clorazepate dipotassium.

PubMed:Relationship of diazepam serum level to antianxiety effects.

PubMed:Valproic acid and diazepam interaction in vivo.

PubMed:A radioreceptor assay to study the affinity of benzodiazepines and their receptor binding activity in human plasma including their active metabolites.

PubMed:Effect of ethanol ingestion on outcome of drug overdose.

PubMed:Disposition, distribution, and liver first-pass effect of pinazepam in the rat.

PubMed:Steady-state plasma desmethyldiazepam during long-term clorazepate use: effects of antacids.

PubMed:[The distribution of drugs between plasma, brain and cerebrospinal fluid in the human].

PubMed:Effects of oral chlordemethyldiazepam on plasma adrenaline and noradrenaline and cardiovascular reactivity in preoperative patients.

PubMed:Anticonvulsant potency of unmetabolized diazepam.

PubMed:Sensitivity of auditory lateralization and temporal order tests to benzodiazepines.

PubMed:Pinazepam: a precursor of N-desmethyldiazepam.

PubMed:Radioimmunoassay of benzodiazepines.

PubMed:Elimination kinetics of desmethyldiazepam in two young and two elderly subjects.

PubMed:Does chlordesmethyldiazepam have a specific anti-erotic effect? Report on five observations.

PubMed:[Bioavailibility of dipotassium chlorazepate].

PubMed:Rapid gas chromatographic measurement of diazepam and its metabolites desmethyldiazepam, oxazepam, and 3-hydroxydiazepam (temazepam) in small samples of plasma.

PubMed:[Anxiolytics in man: studies on sleep and performance (author's transl)].

PubMed:Interaction of caffeine with benzodiazepines: behavioral effects in mice.

PubMed:Clinical bioavailability evaluation of a controlled release formulation of diazepam.

PubMed:Pharmacokinetics of diazepam in epileptic patients and normal volunteers following intravenous administration.

PubMed:[Pharmacokinetic of benzodiazepines in old age].

PubMed:Long-term use of diazepam.

PubMed:The relationship between peak velocity of saccadic eye movements and serum benzodiazepine concentration.

PubMed:Clorazepate and phenobarbital as antiepileptic drugs: a double-blind study.

PubMed:Aspects of the interaction of thyroxine and its binding serum proteins with 1,4-benzodiazepine tranquillizers.

PubMed:A rapid procedure for the screening and quantitation of barbiturates, diazepam, desmethyldiazepam and methaqualone.

PubMed:[Pharmacokinetics of oral prazepam].

PubMed:[Plasma levels following high diazepam doses in intensive-care medicine (author's transl)].

PubMed:Effects of desmethyldiazepam on diazepam kinetics: a study of effects of a metabolite on parent drug disposition.

PubMed:Comparative protein binding of diazepam and desmethyldiazepam.

PubMed:Pharmacological requirements of patients during alcohol withdrawal.

PubMed:The effect of diazepam on rates of fertilization in the CF-1 mouse.

PubMed:Clearance of diazepam can be impaired by its major metabolite desmethyldiazepam.

PubMed:Binding of diazepam and desmethyldiazepam to plasma protein: concentration-dependence and interactions.

PubMed:Effects of two dosages of chlordesmethyldiazepam on mnestic-information processes in normal subjects.

PubMed:Metabolism of pinazepam by rat liver microsomes.

PubMed:Benzodiazepine overdosage: plasma concentrations and clinical outcome.

PubMed:Effect of chloro-N-desmethyldiazepam on serum and brain tryptophan and serotonin in relation to the activity of central serotonergic neurons.

PubMed:Concentrations of N-descyclopropylmethylprazepam in whole-blood, plasma, and milk after administration of prazepam to humans.

PubMed:Plasma diazepam and desmethyldiazepam concentrations during long-term diazepam therapy.

PubMed:Some behavioral effects of chlorodesmethyldiazepam and lorazepam.

PubMed:Effect of age and sex on disposition of desmethyldiazepam formed from its precursor clorazepate.

PubMed:Pharmacokinetics of N-desmethyldiazepam after a single oral dose of clorazepate: the effect of smoking.

PubMed:Studies on some pharmacological activities of 7-nitro-2-amino-5-phenyl-3H-1,5-benzodiazepine (CP 1414 S) in the rat. A comparison with diazepam.

PubMed:Evaluation of an enzyme immunoassay for determining diazepam and nordiazepam in serum and urine.

PubMed:Comparative protein binding of diazepam and desmethyldiazepam.

PubMed:Influence of cimetidine on the pharmacokinetics of desmethyldiazepam and oxazepam.

PubMed:High-performance liquid chromatographic and gas-liquid chromatographic determination of diazepam and nordiazepam in plasma.

PubMed:[Current intravenous anesthetics].

PubMed:Desmethyldiazepam kinetics in the elderly after oral prazepam.

PubMed:Methane negative chemical ionization analysis of 1,3-dihydro-5-phenyl-1,4-benzodiazepin-2-ones.

PubMed:Simultaneous assay of diazepam, chlordiazepoxide, N-desmethyldiazepam, N-desmethylchloridazepoxide, and demoxepam in serum by high performance, liquid chromatography.

PubMed:Effect of diazepam and desmethyldiazepam in spasticity and rigidity. A quantitative study of reflexes and plasma concentrations.

PubMed:Delayed clearance of diazepam due to cimetidine.

PubMed:Diazepam and N-desmethyldiazepam concentrations in saliva, plasma and CSF.

PubMed:Diazepam and N-desmethyldiazepam redistribution after heparin.

PubMed:[Drug catabolism and its significance for pharmacotherapy].

PubMed:Diurnal variations in plasma diazepam concentrations associated with reciprocal changes in free fraction.

PubMed:Determination of some benzodiazepines and metabolites in serum, urine and saliva by high-performance liquid chromatography.

PubMed:Diazepam and N-desmethyldiazepam in saliva of hospital inpatients.

PubMed:Comparative effects of two commercially available blood collection tubes on plasma concentrations of drugs.

PubMed:Withdrawal reaction from long-term, low-dosage administration of diazepam. A double-blind, placebo-controlled case study.

PubMed:Plasma levels of chlorodesmethyldiazepam in humans.

PubMed:Kinetics and neuropsychologic effects of IV diazepam in the presence and absence of its active N-desmethyl metabolite in humans.

PubMed:Anxiety and sedation during a stressful situation after single dose of diazepam versus N-desmethyldiazepam--a controlled trial.

PubMed:Entry of diazepam and its major matabolite into cerebrospinal fluid.

PubMed:Structure activity relationships of selected benzodiazepines as anticonvulsants to local anesthetics.

PubMed:The psychosedative effect of chlordesmethyldiazepam on anxiety states in neurotic and psychotic inpatients.

PubMed:Pharmacokinetics of dipotassium chlorazepate in patients after repeated 50 mg oral doses.

PubMed:Monitoring clorazepate dipotassium as desmethyldiazepam in plasma by electron-capture gas--liquid chromatography.

PubMed:Intravascular factors affecting diazepam binding to human serum albumin.

PubMed:Desmethyldiazepam: a specific radioimmunoassay.

PubMed:Single case study. Diazepam (Valium) detoxification.

PubMed:Effect of age and Billroth gastrectomy on absorption of desmethyldiazepam from clorazepate.

PubMed:Pharmacokinetics of prazepam in man.

PubMed:In vitro effects of diazepam, desmethyldiazepam & nitrazepam on ATPase activity of human fetal brain.

PubMed:Acute and chronic effects of three benzodiazepines in the social interaction anxiety test in mice.

PubMed:[A screening radioimmunoassay for 1,4-benzodiazepines in human blood, serum, and urine using anti-oxazepam-hemisuccinate-antibodies (author's transl)].

PubMed:Single-dose kinetics of prazepam, a precursor of desmethyldiazepam.

PubMed:Effect of age on the pharmacokinetics of diazepam given in conjunction with spinal anesthesia.

PubMed:Sensitive gas chromatographic method for the determination of diazepam and N-desmethyldiazepam in plasma.

PubMed:Analysis for diazepam and nordiazepam by electron-capture gas chromatography and by liquid chromatography.

PubMed:Elimination half-life of nordiazepam.

PubMed:Liquid-chromatographic assay of diazepam and its major metabolites in plasma.

PubMed:Plasma concentrations of medazepam and its metabolites after oral administration.

PubMed:Simultaneous determination of diazepam and its metabolies N-desmethyldiazepam, oxydiazepam and oxazepam in plasma and urine of man and dog by means of high-performance liquid chromatography.

PubMed:Gas chromatographic determination of chlorodesmethyldiazepam and lorazepam in rats and mice.

PubMed:Monitoring diazepam and desmethyldiazepam concentrations in plasma by gas-liquid chromatography, with use of a nitrogen-sensitive detector.

PubMed:Altered elimination of desmethyldiazepam in the elderly.

PubMed:Self-rated sedation and plasma concentrations of desmethyldiazepam following single doses of clorazepate.

PubMed:Effects on learning and memory of 2-week treatments with chlordiazepoxide lactam, N-desmethyldiazepam, oxazepam and methyloxazepam, alone or in combination with alcohol.

PubMed:Plasma concentration of diazepam and N-desmethyldiazepam in children after a single rectal or intramuscular dose of diazepam.

PubMed:Dose-dependent pharmacokinetics of 7-chloro-1,3-dihydro-5-(2'-chlorophenyl)-2H-1,4-benzodiazepin-2-one in dogs.

PubMed:Quantitation of chlordiazepoxide and its metabolites in biological fluids by thin-layer chromatography.

PubMed:Plasma concentrations of diazepam and N-desmethyldiazepam in newborn infants after intravenous, intramuscular, rectal and oral administration.

PubMed:Rapid recovery from massive diazepam overdose.

PubMed:A micromethod for simultaneous estimation of blood levels of some commonly used antiepileptic drugs.

PubMed:Fluorescence--TLC densitometric determination of diazepam and other 1,4-benzodiazepines in serum.

PubMed:Simultaneous gas-chromatographic analysis for diazepam and its major metabolite, desmethyldiazepam, with use of double internal standardization.

PubMed:Immediate and residual effects in man of the metabolites of diazepam.

PubMed:[Clinical pharmacokinetics of diazepam and its biologically active metabolites (author's transl)].

PubMed:Impaired absorption of desmethyldiazepam from clorazepate by magnesium aluminum hydroxide.

PubMed:Pharmacokinetic understanding of antianxiety drug therapy.

PubMed:Plasma concentrations of diazepam and desmethyldiazepam during chronic diazepam therapy.

PubMed:Clorazepate kinetics in treated epileptics.

PubMed:[Studies on metabolism of prazepam. II. Metabolism of prazepam, diazepam and desalkylprazepam by rat liver microsomes (author's transl)].

PubMed:[Binding of prazepam, desalkylprazepam and diazepam to human serum albumin (author's transl)].

PubMed:Plasma and urine concentrations of diazepam and its metabolites in children, adults and in diazepam-intoxicated patients.

PubMed:Effect of a cocktail on diazepam absorption.

PubMed:Diazepam, alcohol and drivers.

PubMed:Determination of benzodiazepine anticonvulsants in plasma by high-performance liquid chromatography.

PubMed:Prazepam, a precursor of desmethyldiazepam.

PubMed:High-performance liquid chromatographic determination of benzodiazepines in human plasma.

PubMed:High-pressure liquid chromatographic analysis of diazepam, oxazepam and N-desmethyldiazepam in human blood.

PubMed:Determination of desmethyldiazepam in plasma by electron-capture GLC: application to pharmacokinetic studies of clorazepate.

PubMed:Thin-layer chromatographic method for determination of diazepam and its major metabolite, N-desmethyldiazepam, in human serum.

PubMed:Determination of N-desmethyldiazepam in plasma by gas chromatography with an internal standard.

PubMed:Conflict behavior in the squirrel monkey: effects of chlordiazepoxide, diazepam and N-desmethyldiazepam.

PubMed:Influence of the 2'-chloro substitution on central activity of desmethyldiazepam.

PubMed:[Determination of dipotassium clorazepate in the plasma by gas chromatography (author's transl)].

PubMed:Rapid determination of diazepam and nordiazepam in plasma by electron capture gas--liquid chromatography. Application in clinical pharmacokinetic studies.

PubMed:Rapid gas chromatographic assay of serum diazepam, N-desmethyldiazepam, and N-desalkylflurazepam.

PubMed:Hydroxylation of three benzodiazepines in vitro.

PubMed:Activity of N-desmethyldiazepam (nordiazepam) [proceedings].

PubMed:Serum medazepam, diazepam, and N-desmethyldiazepam levels after single and multiple oral doses of medazepam.

PubMed:[Important factors determining human distribution and elimination of diazepam].

PubMed:On the hypnogenic and anticonvulsant activities of demethyldiazepam and chlordemethyldiazepam: time-effect relations.

PubMed:Rapid micro-method for the measurement of diazepam and desmethyldiazepam in blood plasma by gas-liquid chromatography.

PubMed:Pharmacokinetics of N-desmethyldiazepam in healthy volunteers after single daily doses of dipotassium chlorazepate.

PubMed:Analysis of medazepam, diazepam, and metabolites in plasma by gas-liquid chromatography with electrolytic conductivity detection.

PubMed:Allergy to diazepam.

PubMed:Disposition of diazepam and its major metabolite desmethyldiazepam in patients with liver disease.

PubMed:Unchanged protein binding and the increase of serum diazepam levels after food intake.

PubMed:Double-blind cross-over clinical comparison of two 2'-chloro benzodiazepines: 7-chloro-5-(2-chlorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one (chlordesmethyldiazepam) versus 7-chloro-5-(o-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one (lorazepam) in neurotic anxiety.

PubMed:Single-blind evaluation of hypnotic activity of chlordesmethyldiazepam in No-placebo-reactor medical patients.

PubMed:[Treatment of epileptic crisis with chlorazepate dipotassium. Clinical study of 48 patients with the determination of serum levels of nordiazepam].

PubMed:Steady-state bioavailability of two clorazepate dipotassium dosage forms.

PubMed:Effect of desmethyldiazepam and chlordesmethyldiazepam on 3',5'-cyclic guanosine monophosphate levels in rat cerebellum.

PubMed:A simplified quantitative method for the simultaneous determination of diazepam and its metabolites in serum by thin-layer chromatography.

PubMed:Quantitative high-performance liquid chromatography of diazepam and N-desmethyldiazepam in blood.

PubMed:Pharmacokinetics and plasma binding of diazepam in man, dog, rabbit, guinea pig and rat.

PubMed:N-desmethyldiazepam: a new metabolite of chlordiazepoxide in man.

PubMed:[Analysis of the structure of the components of the convulsive action of corazole following administration of sulazepam and its metabolites to mice].

PubMed:Effect of N-desmethyldiazepam (nordiazepam) and a precursor, potassium clorazepate, on sleep in man.

PubMed:Feto-maternal concentrations of diazepam and W-demethyldiazepam after intra-amniotic diazepam injection.

PubMed:Pharmacokinetics of N-demethyldiazepam in patients suffering from insomnia and treated with nortriptyline.

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