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polyaspartate
poly(imino((1S)-1-(carboxymethyl)-2-oxo-1,2-ethanediyl))

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CAS Number: 26063-13-8
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Category:information only not used for fragrances or flavors
 
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DG SANTE Food Additives:polyaspartate
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BOC Sciences
For experimental / research use only.
POLYASPARTIC ACID 95%
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
information only not used for fragrances or flavors
Recommendation for polyaspartate usage levels up to:
 not for fragrance use.
 
Recommendation for polyaspartate flavor usage levels up to:
 not for flavor use.
 
Safety References:
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
National Institute of Allergy and Infectious Diseases:Data
Chemidplus:0026063138
 
References:
Pubchem (sid):135065114
 
Other Information:
HMDB (The Human Metabolome Database):Search
FDA Listing of Food Additive Status:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 poly(imino((1S)-1-(carboxymethyl)-2-oxo-1,2-ethanediyl))
 

Articles:

PubMed:Polyaspartate extraction of cadmium ions from contaminated soil: Evaluation and optimization using central composite design.
PubMed:Recovery after PILP remineralization of dentin lesions created with two cariogenic acids.
PubMed:Design of polyaspartic acid peptide-poly (ethylene glycol)-poly (ε-caprolactone) nanoparticles as a carrier of hydrophobic drugs targeting cancer metastasized to bone.
PubMed:Magnetic and pH dual-responsive mesoporous silica nanocomposites for effective and low-toxic photodynamic therapy.
PubMed:Intrafibrillar Mineralization of Self-Assembled Elastin-Like Recombinamer Fibrils.
PubMed:The effect of the antioxidant on the properties of thiolated poly(aspartic acid) polymers in aqueous ocular formulations.
PubMed:Synergistic antitumor efficacy of redox and pH dually responsive micelleplexes for co-delivery of camptothecin and genes.
PubMed:Self-assembling of poly(aspartic acid) with bovine serum albumin in aqueous solutions.
PubMed:Quantification of Paclitaxel and Polyaspartate Paclitaxel Conjugate in Beagle Plasma: Application to a Pharmacokinetic Study.
PubMed:PEGylated polypeptide lipid nanocapsules to enhance the anticancer efficacy of erlotinib in non-small cell lung cancer.
PubMed:Multifunctional Superparamagnetic Nanoparticles: From Synthesis to siRNA Delivery.
PubMed:Glycoprotein asporin as a novel player in tumour microenvironment and cancer progression.
PubMed:Realization of polyaspartamide-based nanoparticles and in vivo lung biodistribution evaluation of a loaded glucocorticoid after aerosolization in mice.
PubMed:Nuclear-targeting TAT-PEG-Asp8-doxorubicin polymeric nanoassembly to overcome drug-resistant colon cancer.
PubMed:Cell Permeating Nano-Complexes of Amphiphilic Polyelectrolytes Enhance Solubility, Stability, and Anti-Cancer Efficacy of Curcumin.
PubMed:Dual functions of a small regulatory subunit in the mitochondrial calcium uniporter complex.
PubMed:Protein adsorption on polyanion/polycation layer-by-layer assembled polyelectrolyte films.
PubMed:Pegylated Polyaspartamide-Polylactide-Based Nanoparticles Penetrating Cystic Fibrosis Artificial Mucus.
PubMed:Effects of osteoformin in the rapid distraction osteogenesis of rabbit mandibles.
PubMed:Solvent-Free Lipase-Catalyzed Synthesis: Unique Properties of Enantiopure D- and L- Polyaspartates and Their Complexation.
PubMed:Preparation of γ-aminopropyltriethoxysilane cross-linked poly(aspartic acid) superabsorbent hydrogels without organic solvent.
PubMed:Synthesis and Properties of pH-, Thermo-, and Salt-Sensitive Modified Poly(aspartic acid)/Poly(vinyl alcohol) IPN Hydrogel and Its Drug Controlled Release.
PubMed:Surface functionalization of microgrooved titanium with dual growth factor-releasing nanoparticles for synergistic osteogenic differentiation of human mesenchymal stem cells.
PubMed:Biodegradable Multiamine Polymeric Vector for siRNA Delivery.
PubMed:Exploring calcium oxalate crystallization: a constant composition approach.
PubMed:Use of polyaspartate as inhibitor of tartaric precipitations in wines.
PubMed:Supermacroporous chemically cross-linked poly(aspartic acid) hydrogels.
PubMed:Influence of phosphoproteins' biomimetic analogs on remineralization of mineral-depleted resin-dentin interfaces created with ion-releasing resin-based systems.
PubMed:Kinetics of aggregation and crystallization of polyaspartic Acid stabilized calcium phosphate particles at high concentrations.
PubMed:An IDB-containing low molecular weight short peptide as an efficient DNA cleavage reagent.
PubMed:Synthesis of polysaccharide-block-polypeptide copolymer for potential co-delivery of drug and plasmid DNA.
PubMed:Ligand-functionalized degradable polyplexes formed by cationic poly(aspartic acid)-grafted chitosan-cyclodextrin conjugates.
PubMed:Biodegradable and pH-responsive nanoparticles designed for site-specific delivery in agriculture.
PubMed:Poly(ornithine-co-arginine-co-glycine-co-aspartic Acid): Preparation via NCA Polymerization and its Potential as a Polymeric Tumor-Penetrating Agent.
PubMed:Enhancement of Pulmozyme activity in purulent sputum by combination with poly-aspartic acid or gelsolin.
PubMed:Biomimetic synthesis of struvite with biogenic morphology and implication for pathological biomineralization.
PubMed:Polyamino acid display on cell surfaces enhances salt and alcohol tolerance of Escherichia coli.
PubMed:Improving the effectiveness of (-)-epigallocatechin gallate (EGCG) against rabbit atherosclerosis by EGCG-loaded nanoparticles prepared from chitosan and polyaspartic acid.
PubMed:Metabolic engineering of microorganisms for the production of L-arginine and its derivatives.
PubMed:Intracellular uptake and pH-dependent release of doxorubicin from the self-assembled micelles based on amphiphilic polyaspartamide graft copolymers.
PubMed:A general strategy to prepare different types of polysaccharide-graft-poly(aspartic acid) as degradable gene carriers.
PubMed:Thiolated poly(aspartic acid) as potential in situ gelling, ocular mucoadhesive drug delivery system.
PubMed:Poly(aspartic acid)-based degradable assemblies for highly efficient gene delivery.
PubMed:Evidence of structural variability among synthetic and biogenic vaterite.
PubMed:When functionalization of PLA surfaces meets Thiol-Yne photochemistry: case study with antibacterial polyaspartamide derivatives.
PubMed:Polypeptide-functionalized NaYF4:Yb(3+),Er(3+) nanoparticles: red-emission biomarkers for high quality bioimaging using a 915 nm laser.
PubMed:Poly aspartic acid peptide-linked PLGA based nanoscale particles: potential for bone-targeting drug delivery applications.
PubMed:Development of anti-scale poly(aspartic acid-citric acid) dual polymer systems for water treatment.
PubMed:Modulated protonation of side chain aminoethylene repeats in N-substituted polyaspartamides promotes mRNA transfection.
PubMed:A novel anabolic agent: a simvastatin analogue without HMG-CoA reductase inhibitory activity.
PubMed:Selective intracellular delivery of proteasome inhibitors through pH-sensitive polymeric micelles directed to efficient antitumor therapy.
PubMed:Effect of pH and temperature upon self-assembling process between poly(aspartic acid) and Pluronic F127.
PubMed:Fluorescent polyion complex nanoparticle that incorporates an internal standard for quantitative analysis of protein kinase activity.
PubMed:Magnetic resonance imaging-visible and pH-sensitive polymeric micelles for tumor targeted drug delivery.
PubMed:A smart drug delivery system from charge-conversion polymer-drug conjugate for enhancing tumor therapy and tunable drug release.
PubMed:Polyaspartic acid functionalized gold nanoparticles for tumor targeted doxorubicin delivery.
PubMed:Development of novel radiogallium-labeled bone imaging agents using oligo-aspartic acid peptides as carriers.
PubMed:Different types of degradable vectors from low-molecular-weight polycation-functionalized poly(aspartic acid) for efficient gene delivery.
PubMed:Chitosan/polyanion surface modification of styrene-butadiene-styrene block copolymer membrane for wound dressing.
PubMed:Polyaspartate, a biodegradable chelant that improves the phytoremediation potential of poplar in a highly metal-contaminated agricultural soil.
PubMed:Dynamics of dilute solutions of poly(aspartic acid) and its sodium salt elucidated from atomistic molecular dynamics simulations with explicit water.
PubMed:Polyaspartic acid coated iron oxide nanoprobes for PET/MRI imaging.
PubMed:Enhancement of proton transport in an oriented polypeptide thin film.
PubMed:Mimicking nanofibrous hybrid bone substitute for mesenchymal stem cells differentiation into osteogenesis.
PubMed:Complex coacervation of poly(ethylene-imine)/polypeptide aqueous solutions: thermodynamic and rheological characterization.
PubMed:Redox- and pH-responsive cysteamine-modified poly(aspartic acid) showing a reversible sol-gel transition.
PubMed:NC-6300, an epirubicin-incorporating micelle, extends the antitumor effect and reduces the cardiotoxicity of epirubicin.
PubMed:Multi-armed poly(aspartate-g-OEI) copolymers as versatile carriers of pDNA/siRNA.
PubMed:Biodegradable and redox-responsive chitosan/poly(L-aspartic acid) submicron capsules for transmucosal delivery of proteins and peptides.
PubMed:A double blind randomised controlled clinical trial comparing a novel anti-stain and calculus reducing dentifrice with a standard fluoride dentifrice.
PubMed:Synergistic behavior of poly(aspartic acid) and Pluronic F127 in aqueous solution as studied by viscometry and dynamic light scattering.
PubMed:Biomineralization mechanisms: a new paradigm for crystal nucleation in organic matrices.
PubMed:Formation of iron(III) (hydr)oxides on polyaspartate- and alginate-coated substrates: effects of coating hydrophilicity and functional group.
PubMed:A direct surface modification of iron oxide nanoparticles with various poly(amino acid)s for use as magnetic resonance probes.
PubMed:Block copolymer cross-linked nanoassemblies improve particle stability and biocompatibility of superparamagnetic iron oxide nanoparticles.
PubMed:Synthesis, characterization, drug-loading capacity and safety of novel pH-independent amphiphilic amino acid copolymer micelles.
PubMed:Poly(L-aspartic acid) nanogels for lysosome-selective antitumor drug delivery.
PubMed:Volume change of double cross-linked poly(aspartic acid) hydrogels induced by cleavage of one of the crosslinks.
PubMed:Controlled enzyme-catalyzed degradation of polymeric capsules templated on CaCO₃: influence of the number of LbL layers, conditions of degradation, and disassembly of multicompartments.
PubMed:Metal-free DNA linearized nuclease based on PASP-polyamine conjugates.
PubMed:Polyaspartamide derivative nanoparticles with tunable surface charge achieve highly efficient cellular uptake and low cytotoxicity.
PubMed:Overcharging in biological systems: reversal of electrophoretic mobility of aqueous polyaspartate by multivalent cations.
PubMed:The tumor accumulation and therapeutic efficacy of doxorubicin carried in calcium phosphate-reinforced polymer nanoparticles.
PubMed:Effect of kaolinite, silica fines and pH on transport of polymer-modified zero valent iron nano-particles in heterogeneous porous media.
PubMed:Macromolecular prodrugs. XIII. Hydrosoluble conjugates of 17β-estradiol and estradiol-17β-valerate with polyaspartamide polymer.
PubMed:Enhanced stability and gene silencing ability of siRNA-loaded polyion complexes formulated from polyaspartamide derivatives with a repetitive array of amino groups in the side chain.
PubMed:Novel pH-sensitive zwitterionic poly(amino acid) derivatives for drug delivery.
PubMed:Synthesis of polyaspartic acid-aminobenzenesulfonic acid grafted copolymer and its scale inhibition performance and dispersion capacity.
PubMed:Voltammetric evaluation on poly α-aspartic acid-zinc ion complex in the helix-coil transition pH region.
PubMed:PEG-detachable cationic polyaspartamide derivatives bearing stearoyl moieties for systemic siRNA delivery toward subcutaneous BxPC3 pancreatic tumor.
PubMed:Polyaspartic acid coated manganese oxide nanoparticles for efficient liver MRI.
PubMed:A plug and play polymeric template driven by supramolecular interactions.
PubMed:pH-Sensitive micelles with cross-linked cores formed from polyaspartamide derivatives for drug delivery.
PubMed:Poly(aspartate) hydrolases: biochemical properties and applications.
PubMed:Synthesis and scale inhibitor performance of polyaspartic acid.
PubMed:In vitro mineralization of dense collagen substrates: a biomimetic approach toward the development of bone-graft materials.
PubMed:Synthesis of a novel zwitterionic biodegradable poly (α,β-L-aspartic acid) derivative with some L-histidine side-residues and its resistance to non-specific protein adsorption.
PubMed:Fully biodegradable self-rolled polymer tubes: a candidate for tissue engineering scaffolds.
PubMed:Hybrid calcium phosphate coatings with the addition of trace elements and polyaspartic acid by a low-thermal process.
PubMed:Polyaspartamide-graft-polymethacrylate nanoparticles for doxorubicin delivery.
PubMed:Disruption of contact lens-associated Pseudomonas aeruginosa biofilms formed in the presence of neutrophils.
PubMed:Effect of hydrophobic octadecyl groups on pH-sensitive aggregation behavior of imidazole-containing polyaspartammide derivatives.
PubMed:Biomineralization: A crystal-clear view.
PubMed:Introduction of β-cyclodextrin into poly(aspartic acid) matrix for adsorption and time-release of ibuprofen.
PubMed:Improved anti-tumor activity of stabilized anthracycline polymeric micelle formulation, NC-6300.
PubMed:The role of collagen in bone apatite formation in the presence of hydroxyapatite nucleation inhibitors.
PubMed:Enzymatic synthesis of poly(α-ethyl β-aspartate) by poly(ethylene glycol) modified poly(aspartate) hydrolase-1.
PubMed:Field-induced columnar transition of biocompatible magnetic colloids: An aging study by magnetotransmissivity.
PubMed:Local Water Dynamics in Coacervated Polyelectrolytes Monitored Through Dynamic Nuclear Polarization-Enhanced H NMR.
PubMed:Kinetics of volume change of poly(succinimide) gels during hydrolysis and swelling.
PubMed:Multicomponent polymeric micelles based on polyaspartamide as tunable fluorescent pH-window biosensors.
PubMed:Folate-targeted supramolecular vesicular aggregates based on polyaspartyl-hydrazide copolymers for the selective delivery of antitumoral drugs.
PubMed:Humic Acid fouling mitigation by antiscalant in reverse osmosis system.
PubMed:Estimating attachment of nano- and submicrometer-particles coated with organic macromolecules in porous media: development of an empirical model.
PubMed:Controlling the growth behaviour of multilayered films via layer-by-layer assembly with multiple interactions.
PubMed:Development of bone-like composites via the polymer-induced liquid-precursor (PILP) process. Part 1: influence of polymer molecular weight.
PubMed:Adsorbed polymer and NOM limits adhesion and toxicity of nano scale zerovalent iron to E. coli.
PubMed:Impact of nanoscale zero valent iron on geochemistry and microbial populations in trichloroethylene contaminated aquifer materials.
PubMed:Growth modification of seeded calcite using carboxylic acids: atomistic simulations.
PubMed:New pegylated polyaspartamide-based polyplexes as gene delivery vectors.
PubMed:Cysteine-functionalized polyaspartic acid: a polymer for coating and bioconjugation of nanoparticles and quantum dots.
PubMed:pH-dependent hemolysis of biocompatible imidazole-grafted polyaspartamide derivatives.
PubMed:The effects of osteoformin on mineralisation and quality of newly formed bone during mandibular distraction osteogenesis in rabbits.
PubMed:A novel potentiometric method for the determination of real crosslinking ratio of poly(aspartic acid) gels.
PubMed:Biological flocculation treatment on distillery wastewater and recirculation of wastewater.
PubMed:Asporin competes with decorin for collagen binding, binds calcium and promotes osteoblast collagen mineralization.
PubMed:Modulation of calcium oxalate dihydrate growth by selective crystal-face binding of phosphorylated osteopontin and polyaspartate peptide showing occlusion by sectoral (compositional) zoning.
PubMed:Fe0 nanoparticles remain mobile in porous media after aging due to slow desorption of polymeric surface modifiers.
PubMed:Polyelectrolyte nanoparticles based on water-soluble chitosan-poly(L-aspartic acid)-polyethylene glycol for controlled protein release.
PubMed:Adsorbed polyelectrolyte coatings decrease Fe(0) nanoparticle reactivity with TCE in water: conceptual model and mechanisms.
PubMed:Construction of nanoscale protein particle using temperature-sensitive elastin-like peptide and polyaspartic acid chain.
PubMed:Neutrophil enhancement of Pseudomonas aeruginosa biofilm development: human F-actin and DNA as targets for therapy.
PubMed:[Poly-aspartamide-glutamic acid grafted low molecular weight polyethylenimine as a novel non-viral gene vector].
PubMed:Partial oxidation ("aging") and surface modification decrease the toxicity of nanosized zerovalent iron.
PubMed:Multiradiate calcium phosphate patterns derived from a gradating polysaccharide-acidic protein system.
PubMed:Poly-L-aspartic acid enhances and prolongs gentamicin-mediated suppression of the CFTR-G542X mutation in a cystic fibrosis mouse model.
PubMed:A facile strategy for in situ core-template-functionalizing siliceous hollow nanospheres for guest species entrapment.
PubMed:Protamine sulfate/poly(L-aspartic acid) polyionic complexes self-assembled via electrostatic attractions for combined delivery of drug and gene.
PubMed:Cloning of poly(aspartic acid) (PAA) hydrolase-1 gene from Pedobacter sp. KP-2 and hydrolysis of thermally synthesized PAA by its gene product.
PubMed:The acidic domain of GPIHBP1 is important for the binding of lipoprotein lipase and chylomicrons.
PubMed:Preparation of chitosan-polyaspartic acid-5-fluorouracil nanoparticles and its anti-carcinoma effect on tumor growth in nude mice.
PubMed:pH-dependent self-assembling behavior of imidazole-containing polyaspartamide derivatives.
PubMed:Ionic strength and composition affect the mobility of surface-modified Fe0 nanoparticles in water-saturated sand columns.
PubMed:Reduced aggregation and sedimentation of zero-valent iron nanoparticles in the presence of guar gum.
PubMed:Bone tissue engineering with premineralized silk scaffolds.
PubMed:Non-invasive optical characterization of biomaterial mineralization.
PubMed:Towards a model of the mineral-organic interface in bone: NMR of the structure of synthetic glycosaminoglycan- and polyaspartate-calcium phosphate composites.
PubMed:Synthesis and swelling properties of novel pH-sensitive poly(aspartic acid) gels.
PubMed:Osteoformin accelerates fresh fracture healing in rats.
PubMed:Contribution of flow field flow fractionation with on line static and dynamic light scattering to the study of hydrosoluble polyelectrolyte complexes.
PubMed:Self-assembled nano-bioreactor from block ionomers with elevated and stabilized enzymatic function.
PubMed:Poly(aspartate-g-PEI800), a polyethylenimine analogue of low toxicity and high transfection efficiency for gene delivery.
PubMed:Application and appreciation of chemical sand fixing agent-poly (aspartic acid) and its composites.
PubMed:Nanoparticles based on the complex of chitosan and polyaspartic acid sodium salt: preparation, characterization and the use for 5-fluorouracil delivery.
PubMed:Patterning inorganic (CaCO3) thin films via a polymer-induced liquid-precursor process.
PubMed:Effect of polycarboxylate blocks on the amidase activity of trypsin through complexation with PEG/polycarboxylate block ionomers.
PubMed:Improvement of inverse polymerase chain reaction by optimal dilution and acidic polypeptides.
PubMed:Metal binding characterization and conformational studies using Raman microscopy of resin-bound poly(aspartic acid).
PubMed:Release of the antimicrobial peptide LL-37 from DNA/F-actin bundles in cystic fibrosis sputum.
PubMed:Production of cyanophycin, a suitable source for the biodegradable polymer polyaspartate, in transgenic plants.
PubMed:Protocell-like microspheres from thermal polyaspartic acid.
PubMed:The effect of poly (aspartic acid-co-lactic acid) nanospheres on the lung metastasis of B16BL6 melanoma cells by intravenous administration.
PubMed:DyNAs: constitutional dynamic nucleic acid analogues.
PubMed:Phase transition behavior of novel pH-sensitive polyaspartamide derivatives grafted with 1-(3-aminopropyl)imidazole.
PubMed:Reduced renal toxicity of nanoparticular amphotericin B micelles prepared with partially benzylated poly-L-aspartic acid.
PubMed:Partial poly(glutamic acid) <--> poly(aspartic acid) exchange in layer-by-layer polyelectrolyte films. Structural alterations in the three-component architectures.
PubMed:Biomimetic assembly of polypeptide-stabilized CaCO(3) nanoparticles.
PubMed:Properties of poly(lactic-co-glycolic acid) nanospheres containing protease inhibitors: camostat mesilate and nafamostat mesilate.
PubMed:The role of polycarboxylic acids in calcium phosphate mineralization.
PubMed:Anionic poly(amino acid)s dissolve F-actin and DNA bundles, enhance DNase activity, and reduce the viscosity of cystic fibrosis sputum.
PubMed:A new biodegradable poly-amino acid: alpha,beta-poly[(N-hydroxypropyl/aminoethyl)-DL-aspartamide-co-L-lysine], a potential nonviral vector for gene delivery.
PubMed:Formation of core-shell type biodegradable polymeric micelles from amphiphilic poly(aspartic acid)-block-polylactide diblock copolymer.
PubMed:Screw-sense inversion characteristic of alpha-helical poly(beta-p-chlorobenzyl L-aspartate) and comparison with other related polyaspartates.
PubMed:Glycosylated macromolecular conjugates of antiviral drugs with a polyaspartamide.
PubMed:Nanocrystalline hydroxyapatite-polyaspartate composites.
PubMed:Enzymatic hydrolysis of alpha- and beta-oligo(L-aspartic acid)s by poly(aspartic acid) hydrolases-1 and 2 from Sphingomonas sp. KT-1.
PubMed:Recognition and stabilization of peptide alpha-helices using templatable nanoparticle receptors.
PubMed:Microbial degradation of poly(amino acid)s.
PubMed:Switching by pulse electric field of the elevated enzymatic reaction in the core of polyion complex micelles.
PubMed:Novel anticoagulant activity of polyamino acid offsets bacterial endotoxin-induced extrinsic hypercoagulation: downregulation of monocytic tissue factor-dependent FVII activation.
PubMed:Biochemical and molecular characterization of poly(aspartic acid) hydrolase-2 from sphingomonas sp. KT-1.
PubMed:Biodegradable hydrogels obtained by photocrosslinking of dextran and polyaspartamide derivatives.
PubMed:Arg82p is a bifunctional protein whose inositol polyphosphate kinase activity is essential for nitrogen and PHO gene expression but not for Mcm1p chaperoning in yeast.
PubMed:[Experimental study on polyaspartic acid inhibition of gentamicin-induced generation of reactive oxygen species in guinea pig cochlea].
PubMed:Sustainable enzymatic preparation of polyaspartate using a bacterial protease.
PubMed:Moderation of oral bacterial adhesion on saliva-coated hydroxyapatite by polyaspartate.
PubMed:Improvement of the functions of osteoblasts seeded on modified poly(D,L-lactic acid) with poly(aspartic acid).
PubMed:Pitting corrosion inhibition of aluminum 2024 by Bacillus biofilms secreting polyaspartate or gamma-polyglutamate.
PubMed:Bioelectronic device consisting of cytochrome c/poly-L-aspartic acid adsorbed hetero-Langmuir-Blodgett films.
PubMed:Dipeptide utilization by the periodontal pathogens Porphyromonas gingivalis, Prevotella intermedia, Prevotella nigrescens and Fusobacterium nucleatum.
PubMed:Fluorescence of indocyanine green in blood: intensity dependence on concentration and stabilization with sodium polyaspartate.
PubMed:Purification and characterization of poly(aspartic acid) hydrolase from Sphingomonas sp. KT-1.
PubMed:Microbial degradation of poly(aspartic acid) by two isolated strains of Pedobacter sp. and Sphingomonas sp.
PubMed:Binding of bone sialoprotein, osteopontin and synthetic polypeptides to hydroxyapatite.
PubMed:Preparation and characterization of size-controlled polymeric micelle containing cis-dichlorodiammineplatinum(II) in the core.
PubMed:[Safety and efficacy of LK565--a new polymer ultrasound contrast medium].
PubMed:Potential tuberculostatic agents: micelle-forming copolymer poly(ethylene glycol)-poly(aspartic acid) prodrug with isoniazid.
PubMed:Preferential utilization of dipeptides by Porphyromonas gingivalis.
PubMed:Sphingomonads involved in the biodegradation of xenobiotic polymers.
PubMed:Plaque mineral induction and inhibition properties in the formation of supragingival calculus.
PubMed:Genetic engineering strategies for purification of recombinant proteins from canola by anion exchange chromatography: an example of beta-glucuronidase.
PubMed:Hydrogen bonding and electrostatic interaction contributions to the interaction of a cationic drug with polyaspartic acid.
PubMed:Anionic effects on the size and shape of apatite crystals grown from physiological solutions.
PubMed:Cytochrome c release from isolated rat liver mitochondria can occur independently of outer-membrane rupture: possible role of contact sites.
PubMed:A cationic lipid emulsion/DNA complex as a physically stable and serum-resistant gene delivery system.
PubMed:Defining the drug incorporation properties of PLA-PEG nanoparticles.
PubMed:Role of anionic proteins in kidney stone formation: interaction between model anionic polypeptides and calcium oxalate crystals.
PubMed:Stabilization of the optical tracer agent indocyanine green using noncovalent interactions.
PubMed:Poly(aspartic acid) degradation by a Sphingomonas sp. isolated from freshwater.
PubMed:Dissolution of synthetic hydroxyapatite in the presence of acidic polypeptides.
PubMed:Identification of the binding region of basic calponin on alpha and beta tubulins.
PubMed:Synthesis and surface characterization of functionalized polylactide copolymer microparticles.
PubMed:Mutation of a gene encoding a putative glycoprotease leads to reduced salt tolerance, altered pigmentation, and cyanophycin accumulation in the cyanobacterium Synechocystis sp. strain PCC 6803.
PubMed:Adhesion of hydroxyapatite crystals to anionic sites on the surface of renal epithelial cells.
PubMed:Dishing up the ocean's riches.
PubMed:Comparative studies on the isothermal characteristics of proteins adsorbed under batch equilibrium conditions to ion-exchange, immobilised metal ion affinity and dye affinity matrices with different ionic strength and temperature conditions.
PubMed:Poly-l-aspartic acid protects cultured human proximal tubule cells against aminoglycoside-induced electrophysiological alterations.
PubMed:Gentamicin inhibits rat renal cortical homotypic endosomal fusion: role of megalin.
PubMed:Effect of polyaspartic acid on pharmacokinetics of gentamicin after single intravenous dose in the dog.
PubMed:Acidic amino acid-rich sequences as binding sites of osteonectin to hydroxyapatite crystals.
PubMed:Formation of hydrated calcium oxalates in the presence of poly-L-aspartic acid.
PubMed:Cholesterol sulphate-reactive autoantibodies are specifically increased in chronic chagasic human patients.
PubMed:Prediction of polyelectrolyte polypeptide structures using Monte Carlo conformational search methods with implicit solvation modeling.
PubMed:Conformational analysis of helical poly(beta-L-aspartate)s by IR dichroism.
PubMed:In vivo pharmacokinetic study for the assessment of poly(L-aspartic acid) as a drug carrier for colon-specific drug delivery.
PubMed:Osteopontin and related phosphorylated sialoproteins: effects on mineralization.
PubMed:Effects and interactions of gentamicin, polyaspartic acid and diuretics on urine calcium concentration.
PubMed:Quantitative analysis of the effect of surface impregnation with biomedical polymers on the proliferation rate of HeLa cells in culture.
PubMed:A rodent model for hemoglobin switching utilizing high performance liquid chromatography.
PubMed:Inhibition of cartilage metalloproteoglycanases and stromelysin by anionic homopolymers.
PubMed:Polyamino acids that inhibit the interaction of yeast translational elongation factor-3 (EF-3) with ribosomes.
PubMed:Atomic force microscopy and molecular modeling of protein and peptide binding to calcite.
PubMed:Effects of polyaspartic acid on pharmacokinetics of tobramycin in two strains of rat.
PubMed:Polymetallic macromolecules are potential contrast agents of improved efficiency.
PubMed:Contractile properties of synthetic cationic polypeptides in guinea-pig isolated trachea.
PubMed:Interactions of matrix proteins from mineralized tissues with octacalcium phosphate.
PubMed:Microtubule-associated proteins, MAP 1A and MAP 1B, interact with F-actin in vitro.
PubMed:Electromigration behavior of poly-(L-glutamate) conformers in concentrated polyacrylamide gels.
PubMed:Biodistribution of micelle-forming polymer-drug conjugates.
PubMed:Enhanced recovery and purification of Aspergillus glucoamylase from Saccharomyces cerevisiae by the addition of poly(aspartic acid) tails.
PubMed:Analysis of micelle formation of an adriamycin-conjugated poly(ethylene glycol)-poly(aspartic acid) block copolymer by gel permeation chromatography.
PubMed:Effect of polyaspartic acid on CdCl2-induced nephrotoxicity in the rat.
PubMed:Rapid analysis of hemoglobin variants by cation-exchange HPLC.
PubMed:Pharmacologic limits of the protective effect of polyaspartic acid on experimental gentamicin nephrotoxicity.
PubMed:Toxicity studies of antiscalant agents using Arbacia punctulata gametes and embryos as test organisms.
PubMed:Adsorption and modification of calcium salt crystal growth by anionic peptides and spermine.
PubMed:Determinants of the in vitro interaction of polyaspartic acid and aminoglycoside antibiotics.
PubMed:Duration of the protective effect of polyaspartic acid on experimental gentamicin nephrotoxicity.
PubMed:Salt bridge induced changes in the secondary structure of ionic polypeptides.
PubMed:Complex allosteric modulation of cardiac muscarinic receptors by protamine: potential model for putative endogenous ligands.
PubMed:Poly-L-aspartic acid does but triiodothyronine does not protect against gentamicin-induced cytotoxicity in the porcine kidney cell line LLC-PK1.
PubMed:Preparation of micelle-forming polymer-drug conjugates.
PubMed:Comparative assessment of poly-L-aspartic and poly-L-glutamic acids as protectants against gentamicin-induced renal lysosomal phospholipidosis, phospholipiduria and cell proliferation in rats.
PubMed:Inhibition of calcium phosphate precipitation by human salivary statherin: structure-activity relationships.
PubMed:Specific inhibition of Physarum polycephalum DNA-polymerase-alpha-primase by poly(L-malate) and related polyanions.
PubMed:Regulation of cultured human mesangial cell growth by ionized macromolecules.
PubMed:Drug-phospholipid interactions: role in aminoglycoside nephrotoxicity.
PubMed:Long-term protection of polyaspartic acid in experimental gentamicin nephrotoxicity.
PubMed:Purification, gene cloning, and sequence analysis of an L-isoaspartyl protein carboxyl methyltransferase from Escherichia coli.
PubMed:Solubilization of asymmetric acetylcholinesterase by polyanions.
PubMed:Pharmacokinetic and toxicological evaluation of a once-daily regimen versus conventional schedules of netilmicin and amikacin.
PubMed:Mechanism of protection afforded by polyaspartic acid against gentamicin-induced phospholipidosis. I. Polyaspartic acid binds gentamicin and displaces it from negatively charged phospholipid layers in vitro.
PubMed:Protection against gentamicin-induced early renal alterations (phospholipidosis and increased DNA synthesis) by coadministration of poly-L-aspartic acid.
PubMed:Mechanism of protection afforded by polyaspartic acid against gentamicin-induced phospholipidosis. II. Comparative in vitro and in vivo studies with poly-L-aspartic, poly-L-glutamic and poly-D-glutamic acids.
PubMed:Inhibition of agrin-induced acetylcholine-receptor aggregation by heparin, heparan sulfate, and other polyanions.
PubMed:Copolymers of glutamic acid and tyrosine are potent inhibitors of oocyte casein kinase II.
PubMed:Polyaspartic acid inhibits gentamicin-induced perturbations of phospholipid metabolism.
PubMed:A simple rheological method for the in vitro assessment of mucin-polymer bioadhesive bond strength.
PubMed:Selective purification of microtubule-associated proteins 1 and 2 from rat brain using poly(L-aspartic acid).
PubMed:Influence of membrane surface potential and of net charge on aminoglycoside binding to the organ of Corti of guinea pigs.
PubMed:Polyaspartic acid protects against gentamicin-induced toxicity: mechanism of action.
PubMed:Inhibition of aminoglycoside-induced nephrotoxicity in rats by polyanionic peptides.
PubMed:The dual role of polyelectrolytes and proteins as mineralization promoters and inhibitors of calcium oxalate monohydrate.
PubMed:Inhibitory effects of poly(L-aspartic acid) on the assembly of brain microtubules and the interaction of microtubule-associated protein 2 with F-actin in vitro.
PubMed:Polyaspartic acid protects against gentamicin nephrotoxicity in the rat.
PubMed:Polyaspartic acid prevents experimental aminoglycoside nephrotoxicity.
PubMed:Comparative assessment of poly-L-aspartic and poly-L-glutamic acids as protectants against aminoglycoside-induced nephrotoxicity.
PubMed:Amino acid sequence and distribution of mRNA encoding a major skeletal muscle laminin binding protein: an extracellular matrix-associated protein with an unusual COOH-terminal polyaspartate domain.
PubMed:Tension and compression in the cytoskeleton of PC-12 neurites. II: Quantitative measurements.
PubMed:Poly(aspartic acid)-dependent fusion of liposomes bearing the quaternary ammonium detergent [[[(1,1,3,3-tetramethylbutyl)cresoxy]ethoxy]ethyl] dimethylbenzylammonium hydroxide.
PubMed:Amino acid sequence of a soybean (Glycine max) seed polypeptide having a poly(L-aspartic acid) structure.
PubMed:Inhibition of renal membrane binding and nephrotoxicity of aminoglycosides.
PubMed:Comparative distribution of free doxorubicin and poly-L-aspartic acid linked doxorubicin in MS-2 sarcoma bearing mice.
PubMed:Reduction of gentamicin nephrotoxicity by the concomitant administration of poly-l-aspartic acid and poly-l-asparagine in rats.
PubMed:Poly-L-aspartic acid as a carrier for doxorubicin: a comparative in vivo study of free and polymer-bound drug.
PubMed:Ca2+-dependent cyclic nucleotide phosphodiesterase is activated by poly(L-aspartic acid).
PubMed:Inhibition of renal membrane binding and nephrotoxicity of gentamicin by polyasparagine and polyaspartic acid in the rat.
PubMed:Novel heparin-activated protein kinase activity in rabbit skeletal muscle.
PubMed:The effects of basic and acidic synthetic polypeptides on the adherence of the oral bacteria, Streptococcus mutans and Streptococcus sanguis, to hydroxyapatite.
PubMed:Influence of urea on the high-performance cation-exchange chromatography of hen egg white lysozyme.
PubMed:Comparison of antitumor effects of daunorubicin covalently linked to poly-L-amino acid carriers.
PubMed:Adsorption of molecules of biological interest onto hydroxyapatite.
PubMed:Cation-exchange high-performance liquid chromatography of proteins on poly(aspartic acid)-silica.
PubMed:Modulation of the calcium-transport ATPase in human erythrocytes by anions.
PubMed:Regulation of the calcium pump ATPase in human erythrocytes.
PubMed:Retardation of calcium oxalate formation by polyacidic peptides.
PubMed:[Preparation of polyasparaginic acid (polyaspartic acid) by the thermal autocondensation of asparaginic acid].
PubMed:Synthesis of polyaspartic acid.
 
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