PubMed:Anticoagulation reversal in the era of the non-vitamin K oral anticoagulants. |
PubMed:Anti-thrombotic effect of rutin isolated from Dendropanax morbifera Leveille. |
PubMed:Biosensors: SERS Encoded Silver Pyramids for Attomolar Detection of Multiplexed Disease Biomarkers (Adv. Mater. 10/2015). |
PubMed:Minipool caprylic acid fractionation of plasma using disposable equipment: a practical method to enhance immunoglobulin supply in developing countries. |
PubMed:Clinical Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of the Novel Factor Xa Inhibitor DY-807f in Healthy Volunteers. |
PubMed:Pharmacokinetics, pharmacodynamics and food effect of LB30870, a novel direct thrombin inhibitor, after single oral doses in healthy men. |
PubMed:Purification and Biochemical Characterization of a Novel Fibrinolytic Enzyme from Culture Supernatant of Cordyceps militaris. |
PubMed:Identification and functional characterization of a novel fungal immunomodulatory protein from Postia placenta. |
PubMed:Structural characterization and anticoagulant activity of a sulfated polysaccharide from the green alga Codium divaricatum. |
PubMed:Using G-Quadruplex/Hemin To "Switch-On" the Cathodic Photocurrent of p-Type PbS Quantum Dots: Toward a Versatile Platform for Photoelectrochemical Aptasensing. |
PubMed:Supplementation with a 9c,11t-rich conjugated linoleic acid blend shows no clear inhibitory effects on platelet function in healthy subjects at low and moderate cardiovascular risk: A randomized controlled trial. |
PubMed:Review of the Target-Specific Oral Anticoagulants in Development for the Treatment and Prevention of Venous Thromboembolism. |
PubMed:Synthetic analogues of flavonoids with improved activity against platelet activation and aggregation as novel prototypes of food supplements. |
PubMed:Intraperitoneal administration of activated protein C prevents postsurgical adhesion band formation. |
PubMed:Sub-nanomolar detection of thrombin activity on a microfluidic chip. |
PubMed:Evaluation of dabigatran for appropriateness of use and bleeding events in a community hospital setting. |
PubMed:Efficacy and safety of argatroban and bivalirudine in patients with suspected heparin-induced thrombocytopenia. |
PubMed:In Vivo AAV1 Transduction With hRheb(S16H) Protects Hippocampal Neurons by BDNF Production. |
PubMed:Managing bleeding and emergency reversal of newer oral anticoagulants: a review for primary care providers. |
PubMed:Strategies for urgent reversal of target-specific oral anticoagulants. |
PubMed:Antiplatelet and anticoagulation agents in acute coronary syndromes: what is the current status and what does the future hold? |
PubMed:Incidence, mortality, and risk factors for oral anticoagulant-associated intracranial hemorrhage in patients with atrial fibrillation. |
PubMed:Non-vitamin K oral anticoagulants in atrial fibrillation: Where are we now? |
PubMed:Antiplatelet effects of Rhus verniciflua stokes heartwood and its active constituents--fisetin, butein, and sulfuretin--in rats. |
PubMed:Cardiovascular, bleeding, and mortality risks in elderly Medicare patients treated with dabigatran or warfarin for nonvalvular atrial fibrillation. |
PubMed:A simple and sensitive label-free fluorescent approach for protein detection based on a Perylene probe and aptamer. |
PubMed:The current landscape of treatment options for venous thromboembolism: a focus on novel oral anticoagulants. |
PubMed:One-pot synthesized DNA-templated Ag/Pt bimetallic nanoclusters as peroxidase mimics for colorimetric detection of thrombin. |
PubMed:Characterization of physical properties of tissue factor-containing microvesicles and a comparison of ultracentrifuge-based recovery procedures. |
PubMed:The effect of peroxynitrite decomposition catalyst MnTBAP on aldehyde dehydrogenase-2 nitration by organic nitrates: role in nitrate tolerance. |
PubMed:Determination of dabigatran, rivaroxaban and apixaban by ultra-performance liquid chromatography - tandem mass spectrometry (UPLC-MS/MS) and coagulation assays for therapy monitoring of novel direct oral anticoagulants. |
PubMed:Oral anticoagulants and status of antidotes for the reversal of bleeding risk. |
PubMed:Hyperbranched rolling circle amplification based electrochemiluminescence aptasensor for ultrasensitive detection of thrombin. |
PubMed:Non-vitamin K antagonist oral anticoagulants (NOACs): clinical evidence and therapeutic considerations. |
PubMed:Serine protease inhibitors as good predictors of meat tenderness: which are they and what are their functions? |
PubMed:Race against the clock: overcoming challenges in the management of anticoagulant-associated intracerebral hemorrhage. |
PubMed:New oral anticoagulants and their implications for dental patients. |
PubMed:Fas-induced apoptosis increases hepatocyte tissue factor procoagulant activity in vitro and in vivo. |
PubMed:Enhancement of platelet aggregation by ursolic Acid and oleanolic Acid. |
PubMed:Treatment discontinuations with new oral agents for long-term anticoagulation: insights from a meta-analysis of 18 randomized trials including 101,801 patients. |
PubMed:Inhibitory effect of allyl isothiocyanate on platelet aggregation. |
PubMed:Dabigatran etexilate in atrial fibrillation. |
PubMed:New orally active anticoagulant agents for the prevention and treatment of venous thromboembolism in cancer patients. |
PubMed:Modulation of proteome expression by F-type lectin during viral hemorrhagic septicemia virus infection in fathead minnow cells. |
PubMed:Impact of nonsynonymous mutations of factor X on the functions of factor X and anticoagulant activity of edoxaban. |
PubMed:Effect of age on bovine subcutaneous fat proteome: molecular mechanisms of physiological variations during beef cattle growth. |
PubMed:Alditols and monosaccharides from sorghum vinegar can attenuate platelet aggregation by inhibiting cyclooxygenase-1 and thromboxane-A2 synthase. |
PubMed:Direct oral anticoagulants in the prevention of venous thromboembolism: evidence from major clinical trials. |
PubMed:Edoxaban: a focused review of its clinical pharmacology. |
PubMed:Dry-cured ham restructured with fibrin. |
PubMed:Preventive effect of fermented Maillard reaction products from milk proteins in cardiovascular health. |
PubMed:Development of an aptamer-based impedimetric bioassay using microfluidic system and magnetic separation for protein detection. |
PubMed:Perilla oil improves blood flow through inhibition of platelet aggregation and thrombus formation. |
PubMed:Thrombin inhibition by dabigatran attenuates atherosclerosis in ApoE deficient mice. |
PubMed:Galla rhois exerts its antiplatelet effect by suppressing ERK1/2 and PLCβ phosphorylation. |
PubMed:Gender, race and diet affect platelet function tests in normal subjects, contributing to a high rate of abnormal results. |
PubMed:[New treatments for stroke and thromboembolism prevention in atrial fibrillation]. |
PubMed:Effect of Morinda citrifolia fruit extract and its iridoid glycosides on blood fluidity. |
PubMed:Dabigatran for stroke prevention in nonvalvular atrial fibrillation: focus in the geriatric population. |
PubMed:Effect of embryonic development on the chicken egg yolk plasma proteome after 12 days of incubation. |
PubMed:Comparison of static and microfluidic protease assays using modified bioluminescence resonance energy transfer chemistry. |
PubMed:A convenient sandwich assay of thrombin in biological media using nanoparticle-enhanced fluorescence polarization. |
PubMed:Emergency department management of patients on novel oral anticoagulant agents. |
PubMed:Antithrombotic alternatives for stroke prevention in atrial fibrillation: critical differences and remaining questions. |
PubMed:Lupine protein hydrolysates inhibit enzymes involved in the inflammatory pathway. |
PubMed:The new era of anticoagulation. |
PubMed:Postprandial coagulation activation in overweight individuals after weight loss: acute and long-term effects of a high-monounsaturated fat diet and a low-fat diet. |
PubMed:Phloretin suppresses thrombin-mediated leukocyte-platelet-endothelial interactions. |
PubMed:Deep vein thrombosis and novel oral anticoagulants: a clinical review. |
PubMed:Dabigatran Use in the Real World: A Multihospital System Experience. |
PubMed:Immobilization of DNA aptamers on polyester cloth for antigen detection by dot blot immunoenzymatic assay (aptablot). |
PubMed:Life-threatening epistaxis and red blood cell polyagglutination under dabigatran. |
PubMed:In vitro predictability of drug-drug interaction likelihood of P-glycoprotein-mediated efflux of dabigatran etexilate based on [I]2/IC50 threshold. |
PubMed:Adverse events in patients initiated on dabigatran etexilate therapy in a pharmacist-managed anticoagulation clinic. |
PubMed:Dabigatran etexilate for thromboembolic prophylaxis in non-valvular atrial fibrillation: the RE-LY study and substudies with commentary. |
PubMed:Practical considerations in the use of novel oral anticoagulants for stroke prevention in nonvalvular atrial fibrillation. |
PubMed:Advantages and limitations of the new anticoagulants. |
PubMed:Clotting factor VIII (FVIII) and thrombin generation in camel plasma: A comparative study with humans. |
PubMed:Improving sensitivity of gold nanoparticle based fluorescence quenching and colorimetric aptasensor by using water resuspended gold nanoparticle. |
PubMed:Effect of tomato industrial processing on phenolic profile and antiplatelet activity. |
PubMed:Selected reaction monitoring method to determine the species origin of blood-based binding agents in meats: a collaborative study. |
PubMed:Evaluation of the oral direct factor Xa inhibitor - betrixaban. |
PubMed:Novel oral anticoagulants for thromboprophylaxis after orthopaedic surgery. |
PubMed:Determining the impact of instrument variation and automated software algorithms on the TGT in hemophilia and normalized plasma. |
PubMed:Enhanced antimicrobial activity of peptide-cocktails against common bacterial contaminants of ex vivo stored platelets. |
PubMed:Hyperimmune globulins and same-day thrombotic adverse events as recorded in a large healthcare database during 2008-2011. |
PubMed:Dabigatran and kidney disease: a bad combination. |
PubMed:Correction of microplate location effects improves performance of the thrombin generation test. |
PubMed:Transitions of care in anticoagulated patients. |
PubMed:Preclinical safety evaluation of human platelets treated with antimicrobial peptides in severe combined immunodeficient mice. |
PubMed:Assessment of immunoglobulin concentrates on thrombogenic activity by thrombin generation assay, prekallikrein activator assay, and size-exclusion chromatography. |
PubMed:Anticoagulation beyond direct thrombin and factor Xa inhibitors: indications for targeting the intrinsic pathway? |
PubMed:New anticoagulant and antiplatelet agents: a primer for the gastroenterologist. |
PubMed:Marine-derived bioactive peptides as new anticoagulant agents: a review. |
PubMed:Extracorporeal therapy for dabigatran removal in the treatment of acute bleeding: a single center experience. |
PubMed:New oral anticoagulants in non-valvular atrial fibrillation. |
PubMed:[Direct oral thrombin inhibitor, "dabigatran"]. |
PubMed:Investigation of protein detection parameters using nanofunctionalized organic field-effect transistors. |
PubMed:Practical use of dabigatran etexilate for stroke prevention in atrial fibrillation. |
PubMed:Moving toward a more ideal anticoagulant: the oral direct thrombin and factor Xa inhibitors. |
PubMed:Rivaroxaban for the treatment of acute coronary syndromes. |
PubMed:Tutorial in oral antithrombotic therapy: biology and dental implications. |
PubMed:Effect of quercetin-rich onion peel extracts on arterial thrombosis in rats. |
PubMed:[Antithrombotic management in atrial fibrillation]. |
PubMed:The reply. |
PubMed:Dabigatran: a nephrological way out. |
PubMed:Stroke prevention in atrial fibrillation--an Asian stroke perspective. |
PubMed:Hinokitiol inhibits platelet activation ex vivo and thrombus formation in vivo. |
PubMed:A new era of oral anticoagulation in atrial fibrillation: implications in clinical practice. |
PubMed:Recent advances in antithrombotic therapy for stroke prevention in patients with atrial fibrillation. |
PubMed:Novel oral anticoagulants for stroke prevention in patients with atrial fibrillation. |
PubMed:Direct thrombin and factor Xa inhibition for stroke prevention in patients with atrial fibrillation. |
PubMed:The discovery of dabigatran etexilate. |
PubMed:Antithrombotics for stroke prevention in non-valvular atrial fibrillation: an update. |
PubMed:The pharmacology and therapeutic use of dabigatran etexilate. |
PubMed:Novel oral anticoagulants for stroke prevention in patients with atrial fibrillation: dawn of a new era. |
PubMed:[Dabigatran as an alternative to warfarin for the prevention of thromboembolism in atrial fibrillation]. |
PubMed:Sulfation pattern of the fucose branch is important for the anticoagulant and antithrombotic activities of fucosylated chondroitin sulfates. |
PubMed:Insect cell-based expression and characterization of a single-chain variable antibody fragment directed against blood coagulation factor VIII. |
PubMed:Metal-organic framework (MOF): a novel sensing platform for biomolecules. |
PubMed:New oral anticoagulants: comparative pharmacology with vitamin K antagonists. |
PubMed:Better hemostatic profiles of never-frozen liquid plasma compared with thawed fresh frozen plasma. |
PubMed:Novel amperometric aptasensor based on analyte-induced suppression of enzyme catalysis in polymeric bionanocomposites. |
PubMed:Recurring extracorporeal circuit clotting during continuous renal replacement therapy in fungal sepsis: successful treatment with argatroban. |
PubMed:The efficacy and safety of platelet-rich plasma and adipose-derived stem cells: an update. |
PubMed:Dabigatran: a cause of hematologic emergency. |
PubMed:Antithrombotic and profibrinolytic activities of isorhamnetin-3-O-galactoside and hyperoside. |
PubMed:Positive outcome after intentional overdose of dabigatran. |
PubMed:Contemporary Anticoagulation Reversal: Focus on Direct Thrombin Inhibitors and Factor Xa Inhibitors. |
PubMed:An update on antithrombotic therapy in atrial fibrillation: the role of newer and emergent drugs. |
PubMed:Flavan-3-ol-enriched dark chocolate and white chocolate improve acute measures of platelet function in a gender-specific way--a randomized-controlled human intervention trial. |
PubMed:Antithrombotic effect of chikusetsusaponin IVa isolated from Ilex paraguariensis (Maté). |
PubMed:Drug, devices, technologies, and techniques for blood management in minimally invasive and conventional cardiothoracic surgery: a consensus statement from the International Society for Minimally Invasive Cardiothoracic Surgery (ISMICS) 2011. |
PubMed:Dabigatran compared with warfarin for stroke prevention with atrial fibrillation: experience in Hong Kong. |
PubMed:The new oral anticoagulants: a challenge for hospital formularies. |
PubMed:Host platelets and, in part, neutrophils mediate lung accumulation of transfused UVB-irradiated human platelets in a mouse model of acute lung injury. |
PubMed:Stroke prevention in atrial fibrillation: impact of novel oral anticoagulants. |
PubMed:Chemical characteristic of an anticoagulant-active sulfated polysaccharide from Enteromorpha clathrata. |
PubMed:Comparative effectiveness of warfarin and new oral anticoagulants for the management of atrial fibrillation and venous thromboembolism: a systematic review. |
PubMed:Phenolic fractions from Trifolium pallidum and Trifolium scabrum aerial parts in human plasma protect against changes induced by hyperhomocysteinemia in vitro. |
PubMed:Coagulation profile of liquid-state plasma. |
PubMed:Enantioselective analysis of melagatran via an LSPR biosensor integrated with a microfluidic chip. |
PubMed:Prediction of drug concentration-time profiles of therapeutic proteins in humans from animals. |
PubMed:Emerging anticoagulant therapies for atrial fibrillation: new options, new challenges. |
PubMed:An evidence-based review of apixaban and its potential in the prevention of stroke in patients with atrial fibrillation. |
PubMed:Antithrombotic therapy for secondary stroke prevention. |
PubMed:Efficacy and safety of fibrin sealant for tissue adherence in facial rhytidectomy. |
PubMed:Hemopericardium and cardiac tamponade associated with dabigatran use. |
PubMed:Exploration of the antiplatelet activity profile of betulinic acid on human platelets. |
PubMed:Acute ischemic stroke treated with intravenous tissue plasminogen activator in a patient taking dabigatran with radiographic evidence of recanalization. |
PubMed:Mammary gland carcinoma in a dog with peripheral blood and bone marrow involvement associated with disseminated intravascular coagulation. |
PubMed:New oral anticoagulants: will they replace warfarin? |
PubMed:General colorimetric detection of proteins and small molecules based on cyclic enzymatic signal amplification and hairpin aptamer probe. |
PubMed:Novel oral anticoagulants: focus on the direct factor Xa inhibitor darexaban. |
PubMed:An aptamer-based fluorescence biosensor for multiplex detection using unmodified gold nanoparticles. |
PubMed:Hemostats, sealants, and adhesives III: a new update as well as cost and regulatory considerations for components of the surgical toolbox. |
PubMed:The Food and Drug Administration decision not to approve the 110 mg dose of dabigatran: give us a way out. |
PubMed:A guidance pathway for the selection of novel anticoagulants in the treatment of atrial fibrillation. |
PubMed:Novel direct factor IIa and Xa inhibitors: mechanisms of action and preclinical studies. |
PubMed:Oral IIa and Xa inhibitors for prevention of stroke in atrial fibrillation: clinical studies and regulatory considerations. |
PubMed:Unifying the mechanism of recombinant FVIIa action: dose dependence is regulated differently by tissue factor and phospholipids. |
PubMed:Enzyme-free fluorescence aptasensor for amplification detection of human thrombin via target-catalyzed hairpin assembly. |
PubMed:[Prevention and treatment of venous thromboembolism: the place of new oral anticoagulants]. |
PubMed:[Old and new oral anticoagulants. Pharmacological perspective]. |
PubMed:New anticoagulants in ischemic heart disease. |
PubMed:Hemopericardium in a patient treated with dabigatran etexilate. |
PubMed:Dabigatran: a new chapter in anticoagulation. |
PubMed:Guidance on the emergent reversal of oral thrombin and factor Xa inhibitors. |
PubMed:Preparation, structure and anticoagulant activity of a low molecular weight fraction produced by mild acid hydrolysis of sulfated rhamnan from Monostroma latissimum. |
PubMed:New oral anticoagulant agents after ACS. |
PubMed:Use of direct thrombin inhibitor for treatment of cerebral venous thrombosis. |
PubMed:Sequence determination and anticoagulant and antithrombotic activities of a novel sulfated fucan isolated from the sea cucumber Isostichopus badionotus. |
PubMed:Dabigatran etexilate: an oral direct thrombin inhibitor for the management of thromboembolic disorders. |
PubMed:Dabigatran: comparison to warfarin, pathway to approval, and practical guidelines for use. |
PubMed:Comparison of enhanced bioluminescence energy transfer donors for protease biosensors. |
PubMed:Aptamers as a sensitive tool to detect subtle modifications in therapeutic proteins. |
PubMed:Newer anticoagulants in cardiovascular disease: a systematic review of the literature. |
PubMed:Hierarchical dendritic gold microstructure-based aptasensor for ultrasensitive electrochemical detection of thrombin using functionalized mesoporous silica nanospheres as signal tags. |
PubMed:New frontiers for stroke prevention in atrial fibrillation. |
PubMed:Concerns regarding the use of dabigatran for stroke prevention in atrial fibrillation. |
PubMed:Dabigatran use in a postoperative coronary artery bypass surgery patient with nonvalvular atrial fibrillation and heparin-PF4 antibodies. |
PubMed:Spontaneous splenic hemorrhage after initiation of dabigatran (Pradaxa) for atrial fibrillation. |
PubMed:Pharmacological basis and clinical evidence of dabigatran therapy. |
PubMed:Advances in antiplatelet therapy. |
PubMed:Dabigatran etexilate: what do hospitalists need to know? |
PubMed:Dabigatran etexilate in clinical practice: confronting challenges to improve safety and effectiveness. |
PubMed:Nicking enzyme based homogeneous aptasensors for amplification detection of protein. |
PubMed:[Anticoagulant therapy for chronic cardiac diseases. Atrial fibrillation, valvular heart disease, congestive heart failure]. |
PubMed:Anti-platelet effects of yuzu extract and its component. |
PubMed:Polyphenol fatty acid esters as serine protease inhibitors: a quantum-chemical QSAR analysis. |
PubMed:Interaction between resveratrol and thrombin and its biological implication. |
PubMed:A novel glycosaminoglycan-like polysaccharide from abalone Haliotis discus hannai Ino: purification, structure identification and anticoagulant activity. |
PubMed:Dabigatran etexilate in atrial fibrillation patients with severe renal impairment: dose identification using pharmacokinetic modeling and simulation. |
PubMed:In vitro anti-platelet effects of simple plant-derived phenolic compounds are only found at high, non-physiological concentrations. |
PubMed:Dabigatran: review of pharmacology and management of bleeding complications of this novel oral anticoagulant. |
PubMed:New anticoagulants for the prevention of stroke in atrial fibrillation. |
PubMed:Hospital-based clinical implications of the novel oral anticoagulant, dabigatran etexilate, in daily practice. |
PubMed:Bivalirudin dosing adjustments for reduced renal function with or without hemodialysis in the management of heparin-induced thrombocytopenia. |
PubMed:Metabolomics-driven nutraceutical evaluation of diverse green tea cultivars. |
PubMed:Activated protein C inhibits high mobility group box 1 signaling in endothelial cells. |
PubMed:Anticoagulant management in the cardiovascular setting. |
PubMed:Recurrent venous thrombosis despite 'optimal anticoagulation therapy' for antiphospholipid syndrome--could new oral anticoagulants solve the problem? |
PubMed:Waldenström's macroglobulinemia in a dog with a bleeding diathesis. |
PubMed:Antithrombotic medication for cardioembolic stroke prevention. |
PubMed:Old versus new oral anticoagulants: focus on pharmacology. |
PubMed:Dabigatran etexilate: A novel oral direct thrombin inhibitor. |
PubMed:Update on anti-coagulation in atrial fibrillation. |
PubMed:Recent progress in anticoagulant therapy: oral direct inhibitors of thrombin and factor Xa. |
PubMed:Edoxaban: pharmacological principles, preclinical and early-phase clinical testing. |
PubMed:The use of dabigatran in elderly patients. |
PubMed:A review of the use of bromelain in cardiovascular diseases. |
PubMed:Anticoagulant drugs: what is new? |
PubMed:Role of emerging antithrombotic therapy in the prevention of cardioembolic complications in patients with atrial fibrillation. |
PubMed:Dabigatran in atrial fibrillation: pharmacology and clinical trials. |
PubMed:New anticoagulants for prevention of stroke in patients with atrial fibrillation. |
PubMed:Stroke management. |
PubMed:[New oral anticoagulants for treatment of venous thromboembolism]. |
PubMed:Spotlight on dabigatran etexilate in the prevention of stroke and systemic embolism in patients with atrial fibrillation. |
PubMed:Dabigatran etexilate: a novel oral thrombin inhibitor for thromboembolic disease. |
PubMed:New options for stroke prevention in atrial fibrillation. |
PubMed:Antithrombotic and profibrinolytic activities of phloroglucinol. |
PubMed:A graphene oxide platform for energy transfer-based detection of protease activity. |
PubMed:Novel oral anticoagulants: focus on stroke prevention and treatment of venous thrombo-embolism. |
PubMed:Drug and dietary interactions of warfarin and novel oral anticoagulants: an update. |
PubMed:Dabigatran etexilate: a review of its use in the prevention of stroke and systemic embolism in patients with atrial fibrillation. |
PubMed:Novel oral factor Xa and thrombin inhibitors in the management of thromboembolism. |
PubMed:The potential role of new oral anticoagulants in the prevention and treatment of thromboembolism. |
PubMed:Effects of peach palm oil on performance, serum lipoproteins and haemostasis in broilers. |
PubMed:A signal-on electrochemiluminescence aptamer biosensor for the detection of ultratrace thrombin based on junction-probe. |
PubMed:[Fusion expression of fibrinolytic enzyme gene PPFE-I from endophytic Paenibacillus polymyxa in Escherichia coli and activity analysis]. |
PubMed:A randomized, open-label pilot study comparing desirudin and argatroban in patients with suspected heparin-induced thrombocytopenia with or without thrombosis: PREVENT-HIT Study. |
PubMed:Absorption and tissue distribution of a novel carboxymethyldextran after oral administration. |
PubMed:A comparative study of antioxidative activity of calcium-D-glucarate, sodium-D-gluconate and D-glucono-1,4-lactone in a human blood platelet model. |
PubMed:Platelet anti-aggregation activities of compounds from Cinnamomum cassia. |
PubMed:Cutting through the statistical fog: understanding and evaluating non-inferiority trials. |
PubMed:Novel oral anticoagulants: implications in the perioperative setting. |
PubMed:Dabigatran: an oral novel potent reversible nonpeptide inhibitor of thrombin. |
PubMed:Oral IIa inhibitors. |
PubMed:[Antiplatelet therapy in coronary heart disease. Some problems and achivements]. |
PubMed:Antioxidant and antiatherogenic activities of pentacyclic triterpenic diols and acids. |
PubMed:Topical recombinant human thrombin in surgical hemostasis. |
PubMed:The influence of platelet-rich plasma on the healing of extraction sockets: an explorative randomised clinical trial. |
PubMed:Novel anticoagulant therapy: principle and practice. |
PubMed:Signal-on electrochemiluminescence biosensor for thrombin based on target-induced conjunction of split aptamer fragments. |
PubMed:[Evaluating thrombolytic efficacy and thrombus targetability of RGDS-liposomes encapsulating subtilisin FS33 in vivo]. |
PubMed:Dabigatran etexilate, a new oral direct thrombin inhibitor, for stroke prevention in patients with atrial fibrillation. |
PubMed:Rationale and design of the PREVENT-HIT study: a randomized, open-label pilot study to compare desirudin and argatroban in patients with suspected heparin-induced thrombocytopenia with or without thrombosis. |
PubMed:Granzyme A and thrombin differentially promote the release of interleukin-8 from alveolar epithelial A549 cells. |
PubMed:Performance of cold-set binding agents in re-formed beef steaks. |
PubMed:New direct thrombin inhibitor becomes available. |
PubMed:Antiviral activity of selected antimicrobial peptides against vaccinia virus. |
PubMed:New approaches to atrial fibrillation management: treat the patient, not the ECG. |
PubMed:Venous thromboembolism: a clinical review. |
PubMed:Update on fondaparinux: role in management of thromboembolic and acute coronary events. |
PubMed:Expression of Acc-Royalisin gene from royal jelly of Chinese honeybee in Escherichia coli and its antibacterial activity. |
PubMed:Dabigatran etexilate in venous thromboembolism. |
PubMed:Thrombin use in surgery: an evidence-based review of its clinical use. |
PubMed:Non ST-elevation acute coronary syndrome. |
PubMed:Topical bovine thrombin: a 21-year review of topical bovine thrombin spontaneous case safety reports submitted to FDA's Adverse Event Reporting System. |
PubMed:Graph-theoretical comparison of protein surfaces reveals potential determinants of cross-reactivity and the molecular mimicry. |
PubMed:[Dabigatran (Pradaxa): efficacy and safety]. |
PubMed:European community and US-FDA approval of recombinant human antithrombin produced in genetically altered goats. |
PubMed:Newer anticoagulants in 2009. |
PubMed:Fibrin sealant: past, present, and future: a brief review. |
PubMed:New anticoagulants in atrial fibrillation. |
PubMed:Antithrombotic and fibrinolytic activities of methanolic extract of aged sorghum vinegar. |
PubMed:Safety of topical thrombins: the ongoing debate. |
PubMed:Pharmacology, pharmacokinetics, and pharmacodynamics of dabigatran etexilate, an oral direct thrombin inhibitor. |
PubMed:Advanced glycation end products strongly activate platelets. |
PubMed:Topical thrombins: benefits and risks. |
PubMed:Oral anticoagulation with factor Xa and thrombin inhibitors: on the threshold of change. |
PubMed:Minimum stable structure of the receptor for advanced glycation end product possesses multi ligand binding ability. |
PubMed:Acute coronary syndrome (unstable angina and non-ST elevation MI). |
PubMed:Aflatoxin B1 misregulates the activity of serine proteases: possible implications in the toxicity of some mycotoxin. |
PubMed:The role of the hemostatic system in murine liver injury induced by coexposure to lipopolysaccharide and trovafloxacin, a drug with idiosyncratic liability. |
PubMed:Fresh from the biologic pipeline. |
PubMed:Novel oral anticoagulants and diet: the potential for interaction. |
PubMed:A review of three stand-alone topical thrombins for surgical hemostasis. |
PubMed:Novel oral anticoagulants. |
PubMed:Functions of coenzyme Q10 in inflammation and gene expression. |
PubMed:Direct comparison of bioluminescence-based resonance energy transfer methods for monitoring of proteolytic cleavage. |
PubMed:Chemical characteristic and anticoagulant activity of the sulfated polysaccharide isolated from Monostroma latissimum (Chlorophyta). |
PubMed:Dabigatran etexilate: an oral direct thrombin inhibitor for prophylaxis and treatment of thromboembolic diseases. |
PubMed:Identification and characterization of a serine protease inhibitor of Paragonimus westermani. |
PubMed:Techniques for quantifying effects of dietary antioxidants on transcription factor translocation and nitric oxide production in cultured cells. |
PubMed:Brave new world: the current and future use of novel anticoagulants. |
PubMed:Direct comparison of fluorescence- and bioluminescence-based resonance energy transfer methods for real-time monitoring of thrombin-catalysed proteolytic cleavage. |
PubMed:Rivaroxaban: an oral direct inhibitor of factor Xa. |
PubMed:Chemical composition of Greek avgotaracho prepared from mullet (Mugil cephalus): nutritional and health benefits. |
PubMed:Changing trends in anti-coagulant therapies. Are heparins and oral anti-coagulants challenged? |
PubMed:Estimating the pathogen safety of manufactured human plasma products: application to fibrin sealants and to thrombin. |
PubMed:A comparison of fish oil, flaxseed oil and hempseed oil supplementation on selected parameters of cardiovascular health in healthy volunteers. |
PubMed:Enteral immuno-enhanced diets with arginine are safe and beneficial for patients early after esophageal cancer surgery. |
PubMed:Advancement in antithrombotics for stroke prevention in atrial fibrillation. |
PubMed:Clinical pharmacokinetics and pharmacodynamics of the oral direct thrombin inhibitor dabigatran etexilate. |
PubMed:Survival of heparins, oral anticoagulants, and aspirin after the year 2010. |
PubMed:Evaluation of biomolecular interactions of sulfated polysaccharide isolated from Grateloupia filicina on blood coagulation factors. |
PubMed:Effect of platelet-rich plasma on cell adhesion, cell migration, and myofibroblastic differentiation in human gingival fibroblasts. |
PubMed:First plasma-free thrombin product approved by FDA. |
PubMed:Antiplatelet aggregation coumarins from the leaves of Murraya omphalocarpa. |
PubMed:Recent developments in antithrombotic therapy: will sodium warfarin be a drug of the past? |
PubMed:Stroke management. |
PubMed:Purification and characterization of a new fibrinolytic enzyme of Bacillus licheniformis KJ-31, isolated from Korean traditional Jeot-gal. |
PubMed:Expression and intein-mediated purification of novel staphylokinase SakSTAR with reduced immunogenicity and antiplatelet and antithrombin activation. |
PubMed:Magnetic resonance imaging, rheological properties, and physicochemical characteristics of meat systems with fibrinogen and thrombin. |
PubMed:The new anticoagulants. |
PubMed:Use of newer anticoagulants in patients with chronic kidney disease. |
PubMed:FDA licenses human thrombin product. |
PubMed:Functional connections and pathways of coenzyme Q10-inducible genes: an in-silico study. |
PubMed:Inhibition by soya isoflavones of human polymorphonuclear leukocyte function: possible relevance for the beneficial effects of soya intake. |
PubMed:Clopidogrel: an updated and comprehensive review. |
PubMed:Screening method for the addition of bovine blood-based binding agents to food using liquid chromatography triple quadrupole mass spectrometry. |
PubMed:Role of the coagulation system in acetaminophen-induced hepatotoxicity in mice. |
PubMed:Percutaneous coronary intervention: the story so far. |
PubMed:Fondaparinux as a treatment option for heparin-induced thrombocytopenia. |
PubMed:No influence of food on the pharmacokinetics, pharmacodynamics or tolerability of the 24mg and 36mg oral tablet formulations of ximelagatran. |
PubMed:Neutrophil interaction with the hemostatic system contributes to liver injury in rats cotreated with lipopolysaccharide and ranitidine. |
PubMed:Anti-hypertensive effect of the Dongchunghacho, Isaria sinclairii, in the spontaneously hypertensive rats. |
PubMed:In vitro reconstitution of antimicrobial pathogen activity by expressed recombinant bovine lactoferrin N-terminal peptide in Escherichia coli. |
PubMed:Aptamers-based assays for diagnostics, environmental and food analysis. |
PubMed:Low-density lipoprotein, collagen, and thrombin models reveal that Rosemarinus officinalis L. exhibits potent antiglycative effects. |
PubMed:Evaluation and management of atrial fibrillation. |
PubMed:Investigational treatments of venous thromboembolism. |
PubMed:Baicalein induction of hydroxyl radical formation via 12-lipoxygenase in human platelets: an ESR study. |
PubMed:Lead-induced procoagulant activation of erythrocytes through phosphatidylserine exposure may lead to thrombotic diseases. |
PubMed:New antithrombotic agents. |
PubMed:Antithrombotic effects of odorless garlic powder both in vitro and in vivo. |
PubMed:Effect of diallyl trisulfide-rich garlic oil on blood coagulation and plasma activity of anticoagulation factors in rats. |
PubMed:Effect of traditional Greek Mediterranean meals on platelet aggregation in normal subjects and in patients with type 2 diabetes mellitus. |
PubMed:Plasma glycoprotein V levels in the general population: normal distribution, associated parameters and implications for clinical studies. |
PubMed:Novel method of expression and purification of hirudin based on pBAD TOPO, pTYB12 vectors and gene synthesis. |
PubMed:A prospective, randomized, controlled trial of autologous platelet-rich plasma gel for the treatment of diabetic foot ulcers. |
PubMed:The challenges of new drugs benefits and risks analysis: lessons from the ximelagatran FDA Cardiovascular Advisory Committee. |
PubMed:Argatroban: a direct thrombin inhibitor with reliable and predictable anticoagulant actions. |
PubMed:The clinical use and immunologic impact of thrombin in surgery. |
PubMed:Purification and characterization of a fibrinolytic enzyme of Bacillus subtilis DC33, isolated from Chinese traditional Douchi. |
PubMed:Evaluation of treatment with direct thrombin inhibitors in patients with heparin-induced thrombocytopenia. |
PubMed:Treatment of heparin-induced thrombocytopenia: is there a role for bivalirudin? |
PubMed:Pharmacokinetics and pharmacodynamics of the oral direct thrombin inhibitor ximelagatran in young healthy Japanese men. |
PubMed:Antiplatelet and antithrombotic activities of methanol extract of Usnea longissima. |
PubMed:Trials and tribulations of non-inferiority: the ximelagatran experience. |
PubMed:Characteristics of a cheese-like food produced by fermentation of the mushroom Schizophyllum commune. |
PubMed:Development of mushrooms for thrombosis prevention by protoplast fusion. |
PubMed:Review and application of serine protease inhibition in coronary artery bypass graft surgery. |
PubMed:Microbial fibrinolytic enzymes: an overview of source, production, properties, and thrombolytic activity in vivo. |
PubMed:Vibrio vulnificus secretes a broad-specificity metalloprotease capable of interfering with blood homeostasis through prothrombin activation and fibrinolysis. |
PubMed:Low potential for interactions between melagatran/ximelagatran and other drugs, food, or alcohol. |
PubMed:Evolving management strategies for heparin-induced thrombocytopenia. |
PubMed:Ximelagatran: a clinical perspective. |
PubMed:PorA protein of Campylobacter jejuni is not a cytotoxin mediating inflammatory diarrhoea. |
PubMed:Pharmacokinetic profile of the oral direct thrombin inhibitor dabigatran etexilate in healthy volunteers and patients undergoing total hip replacement. |
PubMed:Preventing stroke in atrial fibrillation: the SPORTIF programme. |
PubMed:Current issues in anticoagulation. |
PubMed:Ximelagatran--a promising new drug in thromboembolic disorders. |
PubMed:Inhibition of blood platelet adhesion and secretion by different phenolics from Yucca schidigera Roezl. bark. |
PubMed:Oral anticoagulation: challenges in the case-management setting. |
PubMed:The role of oral direct thrombin inhibitors in atrial fibrillation. |
PubMed:New possibilities in anticoagulant management of atrial fibrillation. |
PubMed:Changing the guard in long-term anticoagulation: clinical and economic implications. |
PubMed:The potential for changing prescribing patterns from warfarin to oral direct thrombin inhibitors: clinical scenarios. |
PubMed:Treatment of venous thromboembolism and long-term prevention of recurrence: present treatment options and ximelagatran. |
PubMed:[New perspectives for anticoagulation in non-rheumatic atrial fibrillation: oral antithrombins]. |
PubMed:Ximelagatran in prevention of cardiovascular events. |
PubMed:Role of hepatic fibrin in idiosyncrasy-like liver injury from lipopolysaccharide-ranitidine coexposure in rats. |
PubMed:New blood thinner offers first potential alternative in 50 years: ximelagatran. |
PubMed:Ximelagatran: an oral direct thrombin inhibitor. |
PubMed:Effects of oils rich in eicosapentaenoic and docosahexaenoic acids on the oxidizability and thrombogenicity of low-density lipoprotein. |
PubMed:Sample displacement chromatography of Atlantic Salmon (Salmo salar) thrombin. |
PubMed:[Biological effects of vitamin K and concentration of vitamin K in Norwegian food]. |
PubMed:Orally active direct thrombin inhibitors. |
PubMed:Purification and characterization of Atlantic salmon (Salmo salar) fibrinogen. |
PubMed:Ximelagatran: a new oral anticoagulant. |
PubMed:Lepirudin: a bivalent direct thrombin inhibitor for anticoagulation therapy. |
PubMed:[Cervical esophagogastrostomy dehiscence after gastric pull-up for type I esophageal atresia. Case report of a patient successfully treated with fibrin glue and a review of the literature]. |
PubMed:Ximelagatran: the first oral direct thrombin inhibitor. |
PubMed:Chinese yam (Dioscorea alata cv. Tainung No. 2) feeding exhibited antioxidative effects in hyperhomocysteinemia rats. |
PubMed:Novel fibrinolytic enzyme in fermented shrimp paste, a traditional asian fermented seasoning. |
PubMed:Influence of the lactokinin Ala-Leu-Pro-Met-His-Ile-Arg (ALPMHIR) on the release of endothelin-1 by endothelial cells. |
PubMed:Will direct thrombin inhibitors replace warfarin for preventing embolic events in atrial fibrillation? |
PubMed:Overview of heparin-induced thrombocytopenia. |
PubMed:Searching for preventive measures of cardiovascular events in aged Japanese taxi drivers--the daily rhythm of cardiovascular risk factors during a night duty day. |
PubMed:Recent advances in the discovery and development of direct coagulation factor Xa inhibitors. |
PubMed:Oral direct thrombin inhibitors in clinical development. |
PubMed:The pharmacodynamics and pharmacokinetics of the oral direct thrombin inhibitor ximelagatran and its active metabolite melagatran: a mini-review. |
PubMed:Current anticoagulant therapy--unmet clinical needs. |
PubMed:Pharmacokinetics and pharmacodynamics of ximelagatran, a novel oral direct thrombin inhibitor, in young healthy male subjects. |
PubMed:Ximelagatran versus warfarin for stroke prevention in patients with nonvalvular atrial fibrillation. SPORTIF II: a dose-guiding, tolerability, and safety study. |
PubMed:Influence of age on the pharmacokinetics and pharmacodynamics of ximelagatran, an oral direct thrombin inhibitor. |
PubMed:Antioxidative and antiplatelet effects of aqueous inflorescence Piper betle extract. |
PubMed:Anti-platelet fraction from Galega officinalis L. inhibits platelet aggregation. |
PubMed:[Change of natural antibody levels in patients with cardiovascular diseases by the use of anti-atherogenic diets with processed soy product foods]. |
PubMed:Purification and characterization of a fibrinolytic enzyme produced by Bacillus amyloliquefaciens DC-4 screened from douchi, a traditional Chinese soybean food. |
PubMed:Hyperhomocysteinemia and endothelial function in young subjects: effects of vitamin supplementation. |
PubMed:Enhancement of allyl alcohol hepatotoxicity by endotoxin requires extrahepatic factors. |
PubMed:Jojoba seed meal proteins associated with proteolytic and protease inhibitory activities. |
PubMed:[Future potential indications for an oral thrombin inhibitor]. |
PubMed:Effect of homocysteine reduction by B-vitamin supplementation on markers of clotting activation. |
PubMed:Human platelet aggregation inhibitors from thyme (Thymus vulgaris L.). |
PubMed:Optimizing prophylaxis of venous thromboembolism. |
PubMed:Selective inhibition of coagulation factors: advances in antithrombotic therapy. |
PubMed:Release of annexin V-binding membrane microparticles from cultured human umbilical vein endothelial cells after treatment with camptothecin. |
PubMed:Acid and heat stability of the anticoagulative activity of an onion extract. |
PubMed:Biologically active lipids with antiatherogenic properties from white wine and must. |
PubMed:Comparative efficacy of fibrinogen and platelet supplementation on the in vitro reversibility of competitive glycoprotein IIb/IIIa receptor-directed platelet inhibition. |
PubMed:Impaired platelet aggregation in melanoma patients treated with interferon-alpha-2b adjuvant therapy. |
PubMed:Bivalirudin: a direct thrombin inhibitor. |
PubMed:Current status of the anticoagulant hirudin: its biotechnological production and clinical practice. |
PubMed:Cardiovascular drug highlight: hirudin. |
PubMed:Use of recombinant hirudin in heparin-induced thrombocytopenia and thrombosis (HITT) and renal failure--a case report. |
PubMed:Fibrin sealants in surgical practice: An overview. |
PubMed:Characteristics of wine produced by mushroom fermentation. |
PubMed:Comparative efficacy of fibrinogen and platelet supplementation on the in vitro reversibility of competitive glycoprotein IIb/IIIa (alphaIIb/beta3) receptor-directed platelet inhibition. |
PubMed:A multicenter, prospective, randomized trial evaluating a new hemostatic agent for spinal surgery. |
PubMed:Postprandial triglycerides and blood coagulation. |
PubMed:Characterization of simple and reproducible vascular stenosis model in hypercholesterolemic hamsters. |
PubMed:Recombinant expression of biologically active rat leptin in Escherichia coli. |
PubMed:IgE binding properties of the recombinant ovomucoid third domain expressed in Escherichia coli. |
PubMed:Fibrin sealant: clinical use and the development of the University of Virginia Tissue Adhesive Center. |
PubMed:Biological action of nitric oxide donor compounds on platelets from patients with sickle cell disease. |
PubMed:Pernin: a novel, self-aggregating haemolymph protein from the New Zealand green-lipped mussel, Perna canaliculus (Bivalvia: Mytilidae). |
PubMed:The scientific basis for combined platelet and thrombin-directed pharmacotherapy in acute coronary syndromes. |
PubMed:A cooperative interaction between soy protein and its isoflavone-enriched fraction lowers hepatic lipids in male obese Zucker rats and reduces blood platelet sensitivity in male Sprague-Dawley rats. |
PubMed:Separation of biologically active lipids from red wine. |
PubMed:The link between high-fat meals and postprandial activation of blood coagulation factor VII possibly involves kallikrein. |
PubMed:Antiplatelet activity of soy sauce as functional seasoning. |
PubMed:[Dynamics of the natural antibody level as affected by the biologically active food supplement "Vitol" in patients with hypertensive disease and obesity]. |
PubMed:Inhibitory effect of sulfur-containing compounds in Scorodocarpus borneensis Becc. on the aggregation of rabbit platelets. |
PubMed:Plasticity-related serine proteases in the brain (review). |
PubMed:Expression of recombinant Lym-1 single-chain Fv in Escherichia coli. |
PubMed:Haemostatic profile of the San (Bushmen) relocated to Schmidtsdrif. |
PubMed:Fumaric acid, anti-thrombin substance from Rhizopus javanicus. |
PubMed:Calorie restriction decreases platelet-derived growth factor (PDGF)-A and thrombin receptor mRNA expression in autoimmune murine lupus nephritis. |
PubMed:In vitro and in vivo effects of selenium and selenium with vitamin E on platelet functions in diabetic rats relationship to platelet sorbitol and fatty acid distribution. |
PubMed:Selective induction of a glycoprotein IIIa ligand-induced binding site by fibrinogen and von Willebrand factor. |
PubMed:Amphotericin B induced abnormalities in human platelets. |
PubMed:Modulation of human platelet function by food flavonoids. |
PubMed:Fibrin sealant in the United States: clinical use at the University of Virginia. |
PubMed:Separation of r-hirudin from similar substances by capillary electrophoresis. |
PubMed:Relation of habitual diet and cardiorespiratory fitness to blood coagulation and fibrinolytic factors. |
PubMed:The hemostatic effect of fibrin glue on graft donor sites. |
PubMed:Vinculin is a major platelet protein that undergoes Ca(2+)-dependent tyrosine phosphorylation. |
PubMed:High casein-lactalbumin diet accelerates blood coagulation in rats. |
PubMed:Penicillin-induced dysfunction of platelet membrane glycoproteins. |
PubMed:Penicillin inhibits agonist-induced expression of platelet surface membrane glycoproteins. |
PubMed:Thromboxane production in copper-deficient and marginal platelets: influence of superoxide dismutase and lipid hydroperoxides. |
PubMed:Copper-marginal and copper-deficient diets decrease aortic prostacyclin production and copper-dependent superoxide dismutase activity, and increase aortic lipid peroxidation in rats. |
PubMed:Anticoagulant properties of a fucoïdan fraction. |
PubMed:Studies of women eating diets with different fatty acid composition. III. Fatty acids and prostaglandin synthesis by platelets and cultured human endothelial cells. |
PubMed:Inhibition by albumin of merocyanine 540-mediated photosensitization of platelets and viruses. |
PubMed:The relationship between thromboxane and cytosolic calcium modifiers in rat platelets. |
PubMed:Thrombin attenuates the stimulatory effect of histamine on Ca2+ entry in confluent human umbilical vein endothelial cell cultures. |
PubMed:The effect of a salmon diet on blood clotting, platelet aggregation and fatty acids in normal adult men. |
PubMed:A potent thromboxane formation inhibitor in green tea leaves. |
PubMed:Influence of Bay k 8644 on aequorin-loaded human platelets. |
PubMed:Caseins of various origins and biologically active casein peptides and oligosaccharides: structural and physiological aspects. |
PubMed:A technique for spot application of fibrin glue during open heart operations. |
PubMed:Dihydropyridine-sensitive and insensitive Ca2+ channels in human platelets. |
PubMed:Application of single-donor fibrin glue to burns. |
PubMed:Esophageal atresia--a rabbit model to study anastomotic healing and the use of tissue adhesive fibrin sealant. |
PubMed:Vitamin E supplementation effect on human platelet function, arachidonic acid metabolism, and plasma prostacyclin levels. |
PubMed:Butter-enriched diets reduce arterial prostacyclin production in rats. |
PubMed:The use of fibrin glue in repair of peripheral nerves. |
PubMed:Influence of vitamin E administration on platelet functions in hormonal contraceptive users. |
PubMed:Fibrin glue from stored human plasma. An inexpensive and efficient method for local blood bank preparation. |
PubMed:Barium-impregnated fibrin glue: application to a bleeding duodenal sinus. |
PubMed:Nutrients, platelet function and composition in nine groups of French and British farmers. |
PubMed:Influence of long-term diet modification on platelet function and composition in Moselle farmers. |
PubMed:[Diagnostic aspects and results of drug therapy in pulmonary thromboembolism]. |
PubMed:[Thrombolytic therapy with urokinase in 8 patients with massive pulmonary thromboembolism]. |
PubMed:Reduced aggregation capacity of washed platelets and dysfibrinogenaemia in rats given butylated hydroxytoluene. |
PubMed:Zinc deficiency and impaired platelet aggregation in guinea pigs. |
PubMed:An evaluation of the arachidonate pathway of platelets from companion and food-producing animals, mink, and man. |
PubMed:In vitro releasability of histamine and serotonin: studies of atopic patients. |
PubMed:Platelet aggregation in rats in relation to hyperuricaemia induced by dietary single-cell protein and to protein deficiency. |