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Category:herbicides / pesticides
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Melting Point: | 165.00 °C. @ 760.00 mm Hg (est)
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| Boiling Point: | 643.30 °C. @ 760.00 mm Hg (est)
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| Vapor Pressure: | 5.690000 mmHg @ 20.00 °C. (est) |
| Flash Point: | 649.00 °F. TCC ( 342.90 °C. ) (est)
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| logP (o/w): | -0.700 (est) |
| Soluble in: |
| | water, 157.5 mg/L @ 25 °C (est) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
| |
| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
| |
| Pictogram | |
| |
| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | herbicides / pesticides |
| Recommendation for mesotrione usage levels up to: | | | not for fragrance use.
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| |
| Recommendation for mesotrione flavor usage levels up to: |
| | not for flavor use.
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Safety References:
European Food Safety Authority (EFSA) reference(s):
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Reasoned opinion on the review of the existing maximum residue levels (MRLs) for mesotrione according to Article 12 of Regulation (EC) No 396/2005
View page or View pdf
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Peer review of the pesticide risk assessment of the active substance mesotrione
View page or View pdf
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Outcome of the consultation with Member States, the applicant and EFSA on the pesticide risk assessment for mesotrione in light of confirmatory data
View page or View pdf
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| EPI System: View |
| AIDS Citations:Search |
| Cancer Citations:Search |
| Toxicology Citations:Search |
| EPA ACToR:Toxicology Data |
| EPA Substance Registry Services (SRS):Registry |
| Laboratory Chemical Safety Summary :175967 |
| National Institute of Allergy and Infectious Diseases:Data |
| WGK Germany:2 |
| 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione |
| Chemidplus:0104206828 |
References:
| | 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 175967 |
| Pubchem (sid): | 135154089 |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| 1,3- | cyclohexanedione, 2-(4-(methylsulfonyl)-2-nitrobenzoyl)- | | 2-(4- | methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione | | (2- | nitro-4-(methylsullfonyl))benzoylcyclohexane-1,3-dione |
Articles:
| PubMed:Synthesis and herbicidal evaluation of triketone-containing quinazoline-2,4-diones. |
| PubMed:Effect of herbicide combinations on Bt-maize rhizobacterial diversity. |
| PubMed:Broad 4-hydroxyphenylpyruvate dioxygenase inhibitor herbicide tolerance in soybean with an optimized enzyme and expression cassette. |
| PubMed:Design, synthesis and herbicidal activity of novel quinazoline-2,4-diones as 4-hydroxyphenylpyruvate dioxygenase inhibitors. |
| PubMed:Comparison of three pesticide fate models with respect to the leaching of two herbicides under field conditions in an irrigated maize cropping system. |
| PubMed:Soil surface colonization by phototrophic indigenous organisms, in two contrasted soils treated by formulated maize herbicide mixtures. |
| PubMed:Solar photo-Fenton using peroxymonosulfate for organic micropollutants removal from domestic wastewater: comparison with heterogeneous TiO₂ photocatalysis. |
| PubMed:Photosynthetic responses and accumulation of mesotrione in two freshwater algae. |
| PubMed:Soil sorption and leaching of active ingredients of Lumax® under mineral or organic fertilization. |
| PubMed:Effect of soil properties on pure and formulated mesotrione adsorption onto vertisol (Limagne plane, Puy-de-Dôme, France). |
| PubMed:Mechanisms of tolerance and high degradation capacity of the herbicide mesotrione by Escherichia coli strain DH5-α. |
| PubMed:Novel bacterial bioassay for a high-throughput screening of 4-hydroxyphenylpyruvate dioxygenase inhibitors. |
| PubMed:Optimization of the polar organic chemical integrative sampler for the sampling of acidic and polar herbicides. |
| PubMed:Vitamin E levels in soybean (Glycine max (L.) Merr.) expressing a p-hydroxyphenylpyruvate gene from oat (Avena sativa L.). |
| PubMed:[Preparation and application of solid phase extraction packing of zirconia microsphere coated with sulfonated crosslinked polystyrene]. |
| PubMed:Extraction procedures for the study of phytotoxicity and degradation processes of selected triketones in a water ecosystem. |
| PubMed:Toxicity assessment of the maize herbicides S-metolachlor, benoxacor, mesotrione and nicosulfuron, and their corresponding commercial formulations, alone and in mixtures, using the Microtox(®) test. |
| PubMed:The discovery of 3-(1-aminoethylidene)quinoline-2, 4(1H,3H)-dione derivatives as novel PSII electron transport inhibitors. |
| PubMed:Degradation of triketone herbicides, mesotrione and sulcotrione, using advanced oxidation processes. |
| PubMed:Distinct detoxification mechanisms confer resistance to mesotrione and atrazine in a population of waterhemp. |
| PubMed:Factors affecting the design of slow release formulations of herbicides based on clay-surfactant systems. A methodological approach. |
| PubMed:A review of the mode of toxicity and relevance to humans of the triketone herbicide 2-(4-methylsulfonyl-2-nitrobenzoyl)-1,3-cyclohexanedione. |
| PubMed:In planta mechanism of action of leptospermone: impact of its physico-chemical properties on uptake, translocation, and metabolism. |
| PubMed:The impact of mesotrione on several microbiological activity of chernozem soil. |
| PubMed:Dissipation and dynamics of mesotrione in maize and soil under field ecosystem. |
| PubMed:Electrochemical determination of mesotrione at organoclay modified glassy carbon electrodes. |
| PubMed:Dose-dependent effects of the herbicide mesotrione on soil cyanobacterial communities. |
| PubMed:Synthesis and herbicidal potential of substituted aurones. |
| PubMed:Effect of vegetative filter strips on herbicide runoff under various types of rainfall. |
| PubMed:Dissipation and residues of the herbicide mesotrione in maize and soil in open field. |
| PubMed:Comparative effects of the herbicides chlortoluron and mesotrione on freshwater microalgae. |
| PubMed:Isolation of mesotrione-degrading bacteria from aquatic environments in Brazil. |
| PubMed:Role of soil sorption and microbial degradation on dissipation of mesotrione in plant-available soil water. |
| PubMed:Sensitivity of locally naturalized Panicum species to HPPD- and ALS-inhibiting herbicides in maize. |
| PubMed:Degradation and mineralization of sulcotrione and mesotrione in aqueous medium by the electro-Fenton process: a kinetic study. |
| PubMed:Atmospheric aqueous-phase photoreactivity: correlation between the hydroxyl radical photoformation and pesticide degradation rate in atmospherically relevant waters. |
| PubMed:New procedures for simultaneous determination of mesotrione and atrazine in water and soil. Comparison of the degradation processes of mesotrione and atrazine. |
| PubMed:Kinetic and mechanistic investigations of mesotrione degradation in aqueous medium by Fenton process. |
| PubMed:Comparison of plasma and dry blood spots as samples for the determination of nitisinone (NTBC) by high-performance liquid chromatography-tandem mass spectrometry. Study of the stability of the samples at different temperatures. |
| PubMed:Resistance to HPPD-inhibiting herbicides in a population of waterhemp (Amaranthus tuberculatus) from Illinois, United States. |
| PubMed:Sensitivity of Echinochloa muricata and Echinochloa crus-galli to HPPD- and ALS-inhibiting herbicides in corn. |
| PubMed:Monitoring tyrosinaemia type I: Blood spot test for nitisinone (NTBC). |
| PubMed:Biodegradation pathway of mesotrione: complementarities of NMR, LC-NMR and LC-MS for qualitative and quantitative metabolic profiling. |
| PubMed:Effect of a spreading adjuvant on mesotrione photolysis on wax films. |
| PubMed:The effect of mixing two herbicides mesotrione and nicosulfuron on their photochemical reactivity on cuticular wax film. |
| PubMed:Increase in nutritionally important sweet corn kernel carotenoids following Mesotrione and atrazine applications. |
| PubMed:Lemna minor L. as a model organism for ecotoxicological studies performing 1H NMR fingerprinting. |
| PubMed:Liquid chromatography tandem mass spectrometry method for the quantitation of NTBC (2-(nitro-4-trifluoromethylbenzoyl)1,3-cyclohexanedione) in plasma of tyrosinemia type 1 patients. |
| PubMed:Mesotrione control and pigment concentration of large crabgrass (Digitaria sanguinalis) under varying environmental conditions. |
| PubMed:Isolation and characterization of mesotrione-degrading Bacillus sp. from soil. |
| PubMed:Effects of mesotrione on perennial ryegrass (Lolium perenne L.) carotenoid concentrations under varying environmental conditions. |
| PubMed:Ultra-pressure liquid chromatography-electrospray tandem mass spectrometry for multiresidue determination of pesticides in water. |
| PubMed:Interactions between population density of the Colorado potato beetle, Leptinotarsa decemlineata, and herbicide rate for suppression of solanaceous weeds. |
| PubMed:Toxicity assessment of the herbicides sulcotrione and mesotrione toward two reference environmental microorganisms: Tetrahymena pyriformis and Vibrio fischeri. |
| PubMed:The economics of atrazine. |
| PubMed:Behaviour of sulcotrione and mesotrione in two soils. |
| PubMed:Determination of kinetic and equilibrium regimes in the operation of polar organic chemical integrative samplers. Application to the passive sampling of the polar herbicides in aquatic environments. |
| PubMed:Photodegradation of sulcotrione in various aquatic environments and toxicity of its photoproducts for some marine micro-organisms. |
| PubMed:Biotransformation of the triketone herbicide mesotrione by a Bacillus strain. Metabolite profiling using liquid chromatography/electrospray ionization quadrupole time-of-flight mass spectrometry. |
| PubMed:First isolation and characterization of a bacterial strain that biotransforms the herbicide mesotrione. |
| PubMed:Simulated solar light irradiation of mesotrione in natural waters. |
| PubMed:Metabonomic strategy for the investigation of the mode of action of the phytotoxin (5S,8R,13S,16R)-(-)-pyrenophorol using 1H nuclear magnetic resonance fingerprinting. |
| PubMed:Determination of agrochemical compounds in soya plants by imaging matrix-assisted laser desorption/ionisation mass spectrometry. |
| PubMed:Soil activity and persistence of sulcotrione and mesotrione. |
| PubMed:Photosynthetic and growth responses of zea mays L and four weed species following post-emergence treatments with mesotrione and atrazinet. |
| PubMed:Quantification of the new triketone herbicides, sulcotrione and mesotrione, and other important herbicides and metabolites, at the ng/l level in surface waters using liquid chromatography-tandem mass spectrometry. |
| PubMed:Solid-phase fluoroimmunoassay for the determination of mesotrione--a novel triketone herbicide--in water with direct measurement of the fluorescence onto the solid support. |
| PubMed:Soil persistence of 4-HPPD-inhibitors in different soil types. |
| PubMed:Simultaneous determination of pesticides using a four-band disposable optical capillary immunosensor. |
| PubMed:Primus (florasulam 50 G/L), a new triazolopyrimidine sulfonanilide herbicide to control broad-leaved weeds in maize when applied in early postemergence (1 to 6 leaf stage of maize). Preliminary results. |
| PubMed:Activity of mesotrione on resistant weeds in maize. |
| PubMed:Determination of mesotrione residues and metabolites in crops, soil, and water by liquid chromatography with fluorescence detection. |
| PubMed:Adsorption and degradation of the weak acid mesotrione in soil and environmental fate implications. |
| PubMed:Metabolism of 2-(4-methylsulphonyl-2-nitrobenzoyl)-1,3-cyclohexanedione (mesotrione) in rat and mouse. |
| PubMed:Pharmacokinetics and pharmacodynamics of NTBC (2-(2-nitro-4-fluoromethylbenzoyl)-1,3-cyclohexanedione) and mesotrione, inhibitors of 4-hydroxyphenyl pyruvate dioxygenase (HPPD) following a single dose to healthy male volunteers. |
| PubMed:Mesotrione: a new selective herbicide for use in maize. |
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3D/inchi