ailanthone, 981-15-7

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CODE106604 CODE106604
Product(s):
981-15-7 Ailanthone

CAS Number:	981-15-7	3D/inchi
FDA UNII:	Search
Nikkaji Web:	J21.167B
XlogP3-AA:	-1.10 (est)
Molecular Weight:	376.40568000
Formula:	C20 H24 O7
BioActivity Summary:	listing
NMR Predictor:	Predict (works with chrome, Edge or firefox)

Category:natural substances and extractives

US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:

Google Scholar:	Search
Google Books:	Search
Google Scholar: with word "volatile"	Search
Google Scholar: with word "flavor"	Search
Google Scholar: with word "odor"	Search
Google Patents:	Search
US Patents:	Search
EU Patents:	Search
Pubchem Patents:	Search
PubMed:	Search
NCBI:	Search

Physical Properties:

Assay:	95.00 to 100.00
Food Chemicals Codex Listed:	No
Boiling Point:	641.00 °C. @ 760.00 mm Hg (est)
Flash Point:	449.00 °F. TCC ( 231.60 °C. ) (est)
logP (o/w):	-0.760 (est)
Soluble in:
	water, 2637 mg/L @ 25 °C (est)

Organoleptic Properties:

Odor and/or flavor descriptions from others (if found).

Cosmetic Information:

None found

Suppliers:

Alfa Biotechnology

For experimental / research use only.

Ailanthone 98%

BOC Sciences

For experimental / research use only.

Ailanthone

ExtraSynthese

For experimental / research use only.

Ailanthone

Safety Information:


Hazards identification

Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements

Pictogram

Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intraperitoneal-mouse LD50 31400 ug/kg European Journal of Medicinal Chemistry--Chimie Therapeutique. Vol. 26, Pg. 345, 1991. oral-mouse LD50 9800 ug/kg Parassitologia. Vol. 10, Pg. 215, 1968.
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in Use Information:

Category:
natural substances and extractives
Recommendation for ailanthone usage levels up to:
	not for fragrance use.

Recommendation for ailanthone flavor usage levels up to:
	not for flavor use.

Safety References:

EPI System: View

AIDS Citations:Search

Cancer Citations:Search

Toxicology Citations:Search

EPA ACToR:Toxicology Data

EPA Substance Registry Services (SRS):Registry

Laboratory Chemical Safety Summary :72965

National Institute of Allergy and Infectious Diseases:Data

Chemidplus:0000981157

References:

NIST Chemistry WebBook:	Search Inchi
Pubchem (cid):	72965
Pubchem (sid):	135030641

Other Information:

(IUPAC):	Atomic Weights of the Elements 2011 (pdf)
Videos:	The Periodic Table of Videos
tgsc:	Atomic Weights use for this web site
(IUPAC):	Periodic Table of the Elements
CHEBI:	View
CHEMBL:	View
KEGG (GenomeNet):	C08747
HMDB (The Human Metabolome Database):	Search
VCF-Online:	VCF Volatile Compounds in Food
ChemSpider:	View
Wikipedia:	View

Potential Blenders and core components note

None Found

Potential Uses:

None Found

Occurrence (nature, food, other):note

ailanthus altissima
Search Trop Picture

Synonyms:

	ailantone
(1-beta,11-beta,12-alpha)-11,20-	epoxy-1,11,12-trihydroxypicrasa-3,13(21)-diene-2,16-dione
2H-1,11c-(	epoxymethano)phenanthro(10,1-bc)pyran-5,10(3H,6ah)-dione, 1,3a,4,7,7a,11,11a,11b-octahydro-8,11a-b-dimethyl-3-methylene-1-a,2-b,11-b-trihydroxy-
	picrasa-3,13(21)-dien-2,16-dione, 11,20-epoxy-1,11,12-trihydroxy-, (1b,11b,12a)

Articles:

PubMed:Herbicide activity of extracts from Ailanthus altissima (Simaroubaceae).

PubMed:Quassinoids can induce mitochondrial membrane depolarisation and caspase 3 activation in human cells.

PubMed:Antiplasmodial activity of extracts and quassinoids isolated from seedlings of Ailanthus altissima (Simaroubaceae).

PubMed:Isolation of phytotoxic compounds from tree-of-heaven (Ailanthus altissima swingle).

PubMed:Anti-tuberculosis activity of quassinoids.

PubMed:Quassinoids as inhibitors of Epstein-Barr virus early antigen activation.

PubMed:Antitumor activity of novel ailanthone derivatives in vitro and in vivo.

PubMed:[Antiamebic properties of some derivatives of ailantone and quassin].

Notes:

None found

ailanthone picrasa-3,13(21)-dien-2,16-dione, 11,20-epoxy-1,11,12-trihydroxy-, (1b,11b,12a)

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Articles:

ailanthone
picrasa-3,13(21)-dien-2,16-dione, 11,20-epoxy-1,11,12-trihydroxy-, (1b,11b,12a)