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Articles:

PubMed:Antioxidant and α-amylase inhibitory activities of extract and isolates from Zygogynum pancheri subsp. arrhantum.

PubMed:Anethole induces apoptotic cell death accompanied by reactive oxygen species production and DNA fragmentation in Aspergillus fumigatus and Saccharomyces cerevisiae.

PubMed:The pungent substances piperine, capsaicin, 6-gingerol and polygodial inhibit the human two-pore domain potassium channels TASK-1, TASK-3 and TRESK.

PubMed:Prophylactic strategies in recurrent vulvovaginal candidiasis: a 2-year study testing a phytonutrient vs itraconazole.

PubMed:Medicinal plants of Chile: evaluation of their anti-Trypanosoma cruzi activity.

PubMed:Laboratory assessment of the antifouling potential of a soluble-matrix paint laced with the natural compound polygodial.

PubMed:Comparative antifeedant activities of polygodial and pyrethrins against whiteflies (Bemisia tabaci) and aphids (Myzus persicae).

PubMed:Screening for antioxidant and detoxification responses in Perna canaliculus Gmelin exposed to an antifouling bioactive intended for use in aquaculture.

PubMed:Comparative study on the larvicidal activity of drimane sesquiterpenes and nordrimane compounds against Drosophila melanogaster til-til.

PubMed:Drimanes from Drimys brasiliensis with leishmanicidal and antimalarial activity.

PubMed:Chemical constituents derived from Drimys brasiliensis Miers (Winteraceae).

PubMed:Drimendiol, a drimane sesquiterpene with quorum sensing inhibition activity.

PubMed:Structural requirements for the antifungal activities of natural drimane sesquiterpenes and analogues, supported by conformational and electronic studies.

PubMed:Screening for negative effects of candidate ascidian antifoulant compounds on a target aquaculture species, Perna canaliculus Gmelin.

PubMed:Distribution of drimane sesquiterpenoids and tocopherols in liverworts, ferns and higher plants: Polygonaceae, Canellaceae and Winteraceae species.

PubMed:Red leaf margins indicate increased polygodial content and function as visual signals to reduce herbivory in Pseudowintera colorata.

PubMed:Preventing ascidian fouling in aquaculture: screening selected allelochemicals for anti-metamorphic properties in ascidian larvae.

PubMed:Protective effect of an oral natural phytonutrient in recurrent vulvovaginal candidiasis: a 12-month study.

PubMed:Exploring natural products for new taste sensations.

PubMed:Morphological changes of the filamentous fungus Mucor mucedo and inhibition of chitin synthase activity induced by anethole.

PubMed:Evidence for involvement of TRPA1 in the detection of vibrations by hair bundle mechanoreceptors in sea anemones.

PubMed:Anti-leishmanial and anti-trypanosomal potential of polygodial isolated from stem barks of Drimys brasiliensis Miers (Winteraceae).

PubMed:Drug-induced permeabilization of S. cerevisiae.

PubMed:Chemotaxonomy of Pseudowintera: sesquiterpene dialdehyde variants are species markers.

PubMed:Ugandenial A, a new drimane-type sesquiterpenoid from Warburgia ugandensis.

PubMed:Influence of plant part, season of collection and content of the main active constituent, on the antifungal properties of Polygonum acuminatum Kunth.

PubMed:Sesquiterpene dialdehydes inhibit MSU crystal-induced superoxide production by infiltrating neutrophils in an in vivo model of gouty inflammation.

PubMed:Miogadial and miogatrial with alpha,beta-unsaturated 1,4-dialdehyde moieties--novel and potent TRPA1 agonists.

PubMed:Cytotoxic sesquiterpenoids from Winteraceae of Caledonian rainforest.

PubMed:Mioganal, a novel pungent principle in myoga (Zingiber mioga Roscoe) and a quantitative evaluation of its pungency.

PubMed:TRPA1 mediates the noxious effects of natural sesquiterpene deterrents.

PubMed:Antifeedant activity of some polygodial derivatives.

PubMed:Secondary metabolites of Cinnamosma madagascariensis and their alpha-glucosidase inhibitory properties.

PubMed:From labdanes to drimanes. Degradation of the side chain of dihydrozamoranic acid.

PubMed:Enantioselective synthesis and vanilloid activity evaluation of 1-beta-(p-methoxycinnamoyl)polygodial, an antinociceptive compound from Drymis winteri barks.

PubMed:Naturally occurring compounds affect glutamatergic neurotransmission in rat brain.

PubMed:Effect of a novel phyto-compound on mucosal candidiasis: further evidence from an ex vivo study.

PubMed:Drimanes and other terpenoids from the fern Thelypteris hispidula (Decne.) Reed.

PubMed:Anethole, a potential antimicrobial synergist, converts a fungistatic dodecanol to a fungicidal agent.

PubMed:A novel labdane-type trialdehyde from myoga (Zingiber mioga Roscoe) that potently inhibits human platelet aggregation and human 5-lipoxygenase.

PubMed:Native Kenyan plants as possible alternatives to methyl bromide in soil fumigation.

PubMed:Phytochemistry and antifungal properties of the newly discovered tree Pleodendron costaricense.

PubMed:The sesquiterpenes polygodial and drimanial in vitro affect glutamatergic transport in rat brain.

PubMed:Comparison of volatile constituents of Persicaria odorata(Lour.) Soják (Polygonum odoratum Lour.) and Persicaria hydropiper L. Spach (Polygonum hydropiper L.).

PubMed:Subchronic toxicity study of water pepper extract in F344 rats.

PubMed:Pharmacological characterisation of the plant sesquiterpenes polygodial and drimanial as vanilloid receptor agonists.

PubMed:Preventive strategy for Candida gut translocation during ischemia-reperfusion injury supervening on protein-calorie malnutrition.

PubMed:Antibacterial activity of polygodial.

PubMed:Depletion of glutathione as a cause of the promotive effects of polygodial, a sesquiterpene on the production of reactive oxygen species in Saccharomyces cerevisiae.

PubMed:Antifungal activity of drimane sesquiterpenes from Drimys brasiliensis using bioassay-guided fractionation.

PubMed:Multifunctional action of antifungal polygodial against Saccharomyces cerevisiae: involvement of pyrrole formation on cell surface in antifungal action.

PubMed:Naturally occurring antifungal agents against Zygosaccharomyces bailii and their synergism.

PubMed:In view of an optimal gut antifungal therapeutic strategy: an in vitro susceptibility and toxicity study testing a novel phyto-compound.

PubMed:Inhibition of the mitochondrial ATP synthesis by polygodial, a naturally occurring dialdehyde unsaturated sesquiterpene.

PubMed:Effect of EDTA alone and in combination with polygodial on the growth of Saccharomyces cerevisiae.

PubMed:A complete 1H and 13C NMR data assignment for four drimane sesquiterpenoids isolated from Drimys winterii.

PubMed:Screening for microtubule-disrupting antifungal agents by using a mitotic-arrest mutant of Aspergillus nidulans and novel action of phenylalanine derivatives accompanying tubulin loss.

PubMed:Evidence for the involvement of vanilloid receptor in the antinociception produced by the dialdeydes unsaturated sesquiterpenes polygodial and drimanial in rats.

PubMed:Synergism of polygodial and trans-cinnamic acid on inhibition of root elongation in lettuce seedling growth bioassays.

PubMed:Synthesis and in vitro trypanocide activity of several polycyclic drimane-quinone derivatives.

PubMed:Protective effects of polygodial on gastric mucosal lesions induced by necrotizing agents in rats and the possible mechanisms of action.

PubMed:Role of nitric oxide and K+ channels in relaxation induced by polygodial in rabbit corpus cavernosum in vitro.

PubMed:Protective effects of polygodial and related compounds on ethanol-induced gastric mucosal lesions in rats: structural requirements and mode of action.

PubMed:Additional evidence for the anti-inflammatory and anti-allergic properties of the sesquiterpene polygodial.

PubMed:Naturally occurring anti-Salmonella agents.

PubMed:Occurrence of polygodial and 1-(2,4,6-trimethoxyphenyl)-but-2-en-1-one from some ferns and liverworts: role of pungent components in bryophytes and pteridophytes evolution.

PubMed:Polygodial, the fungitoxic component from the Brazilian medicinal plant Polygonum punctatum.

PubMed:A sesquiterpene drimane with antinociceptive activity from Drimys winteri bark.

PubMed:Antifungal mechanism of polygodial.

PubMed:Synthesis of (+)-cyclozonarone and the absolute configuration of naturally occurring (-)-cyclozonarone.

PubMed:Polygodial, a potent attachment-inhibiting substance for the blue mussel, Mytilus edulis galloprovincialis from Tasmannia lanceolata.

PubMed:Effect of polygodial on the mitochondrial ATPase of Saccharomyces cerevisiae.

PubMed:Action of polygodial on agonist-induced contractions of the rat portal vein in vitro.

PubMed:Mechanisms underlying the relaxation caused by the sesquiterpene polygodial in vessels from rabbit and guinea-pig.

PubMed:Assessment of mechanisms involved in antinociception caused by sesquiterpene polygodial.

PubMed:In vitro antifungal susceptibilities of Candida albicans and other fungal pathogens to polygodial, a sesquiterpene dialdehyde.

PubMed:Isolation and identification of active compounds from Drimys winteri barks.

PubMed:Polygodial Inhibits Carbachol-induced Muscarinic Acetylcholine Receptor Signal Transduction.

PubMed:Anti-hyperalgesic properties of the extract and of the main sesquiterpene polygodial isolated from the barks of Drymis winteri (Winteraceae).

PubMed:Action of polygodial, a sesquiterpene isolated from Drymis winteri, in the guinea-pig ileum and trachea 'in vitro'.

PubMed:Polygodial-induced noradrenaline release in human neuroblastoma SH-SY5Y cells.

PubMed:Polygodial induces inositol phosphate turnover in human neuroblastoma SH-SY5Y cells.

PubMed:Identification and characterization of inhibitors of peptido-leukotriene-synthesis from Petasites hybridus.

PubMed:Sesquiterpenoid unsaturated dialdehydes increase the concentration of intracellular free Ca2+ in human neuroblastoma SH-SY5Y cells.

PubMed:Potentiation of antifungal activity of sesquiterpene dialdehydes against Candida albicans and two other fungi.

PubMed:The effect of six sesquiterpenoid unsaturated dialdehydes on cell membrane permeability in human neuroblastoma SH-SY5Y cells.

PubMed:Antimicrobial agents from Licaria puchuri-major and their synergistic effect with polygodial.

PubMed:Comparison of the antimicrobial and cytotoxic activities of twenty unsaturated sesquiterpene dialdehydes from plants and mushrooms.

PubMed:The cytotoxicity of 22 sesquiterpenoid unsaturated dialdehydes, as determined by the neutral red absorption assay and by protein determination.

PubMed:Synthesis of antifeedants for insects: novel behaviour-modifying chemicals from plants.

PubMed:Activity of drimane antifeedants and related compounds against aphids, and comparative biological effects and chemical reactivity of (-)- and (+)-polygodial.

PubMed:Occurrence of olepupuane in two mediterranean nudibranchs: a protected form of polygodial.

PubMed:Polygodial, an antifungal potentiator.

PubMed:Insect antifeedant activity and hot taste for humans of selected natural and synthetic 1,4-dialdehydes.

PubMed:Dorid nudibranch elaborates its own chemical defense.

PubMed:Antibiotic substances from New Zealand plants. II. Polygodial, an anti-Candida agent from Pseudowintera colorata.

PubMed:Stereospecificity of allergic contact dermatitis (ACD) to enantiomers. Part III. experimentally induced ACD to a natural sesquiterpene dialdehyde, polygodial in guinea pigs.

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