oleth-20
poly(oxy-1,2-ethanediyl), .alpha.-9-(Z)-octadecenyl-.omega.-hydroxy (20 mol EO average molar ratio)
 
Notes:
emulsifying agent; used as vehicle for organic compunds in aqueous solutions.
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2-[(Z)-octadec-9-enoxy]ethanol (peg-20) (Click)
CAS Number: 9004-98-2Picture of molecule
Other: 115453-13-9
ECHA ELINCS - REACH Pre-Reg: 500-016-2
FDA UNII: ABC6L5D75I
XlogP3-AA: 7.30 (est)
Formula: (C2 H4 O)mult-C18 H36 O
NMR Predictor: Predict (works with chrome or firefox)
Category: emulsifiers, surfactants
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
PubMed: Search
NCBI: Search
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Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Boiling Point: 416.00 to  417.00 °C. @ 760.00 mm Hg (est)
Flash Point: > 200.00 °F. TCC ( > 93.33 °C. )
logP (o/w): 7.557 (est)
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Organoleptic Properties:
Odor Strength: none
 
Odor Description:
at 100.00 %. 
bland
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: cleansing agents
surfactants
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Suppliers:
Chemical-navi - Nikkol
NIKKOL BO-20V
Odor: characteristic
Use: Solubilizer; plant-derived
Croda
Brij™ O20
Odor: bland
Use: Solubiliser and emulsifier for gel shaving products.
Kao Corporation
FINDET 1816/32-E
Odor: characteristic
Use: Detergent, foaming, wetting, dispersing agent, emulsifier and solubilizer for different fields.
Kao Corporation
FINDET 1816/3220
Lipo Chemicals
Lipocol® O-20
Odor: characteristic
Use: Lipocol® O-20 is an effective co-emulsifier. It is also a solubilizer for fragrances and other polar oils. It is suggested for skin care products, hair pomades, after shaves and skin toners.
Lubrizol Corporation
Chemonic™ OE-20 Ethoxylated Alcohol
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50  70000 mg/kg
Farm Chemicals Handbook. Vol. -, Pg. C123, 1991.

oral-rat LD50  25800 mg/kg
Soap, Perfumery & Cosmetics. Vol. 38, Pg. 47, 1965.

oral-rat LD50  2770 mg/kg
Soap, Perfumery & Cosmetics. Vol. 38, Pg. 47, 1965.

intraperitoneal-rat LD50  235 mg/kg
Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 42, Pg. 556, 1953.

oral-rat LD50  2700 mg/kg
Soap, Perfumery & Cosmetics. Vol. 38, Pg. 47, 1965.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: emulsifiers, surfactants
Recommendation for oleth-20 usage levels up to:
 not for fragrance use.
 
Recommendation for oleth-20 flavor usage levels up to:
 not for flavor use.
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Safety References:
EPI System: View
Cancer Citations: Search
Toxicology Citations: Search
EPA Substance Registry Services (TSCA): 9004-98-2
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 5364713
National Institute of Allergy and Infectious Diseases: Data
 2-[(Z)-octadec-9-enoxy]ethanol (peg-20)
Chemidplus: 0009004982
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References:
 2-[(Z)-octadec-9-enoxy]ethanol (peg-20)
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 9004-98-2
Pubchem (cid): 5364713
Pubchem (sid): 135020877
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Other Information:
(IUPAC): Atomic Weights of the Elements 2009
(IUPAC): Atomic Weights of the Elements 2009 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
HMDB (The Human Metabolome Database): Search
Household Products: Search
ChemSpider: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
 emulsifying agents 
 surfactants 
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Occurrence (nature, food, other): note
 not found in nature
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Synonyms:
 ameroxol OE-20
 brij 98
 brij O20
 chemonic OE-20 ethoxylated alcohol
 findet 1816/32-E
 findet 1816/3220
 lipocol O-20
 nikkol BO-20V
2-[(Z)-octadec-9-enoxy]ethanol (peg-20)
 peg-20 oleyl ether
 poly(oxy-1,2-ethanediyl), .alpha.-9-(Z)-octadecenyl-.omega.-hydroxy (20 mol EO average molar ratio)
 polyethylene glycol (20) oleyl ether
 polyoxyethylene (20) oleyl ether
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Articles:
PubMed: Transdermal absorption of natural progesterone from alcoholic gel formulations with hydrophilic surfactant.
PubMed: Idebenone loaded solid lipid nanoparticles: calorimetric studies on surfactant and drug loading effects.
PubMed: Idebenone-loaded solid lipid nanoparticles for drug delivery to the skin: in vitro evaluation.
PubMed: In vitro evaluation on a model of blood brain barrier of idebenone-loaded solid lipid nanoparticles.
PubMed: Differential scanning calorimetry studies on sunscreen loaded solid lipid nanoparticles prepared by the phase inversion temperature method.
PubMed: Vehicle effects on in vitro release and skin permeation of octylmethoxycinnamate from microemulsions.
PubMed: In-vitro human skin penetration of the fragrance material geranyl nitrile.
PubMed: Effect of oil phase lipophilicity on in vitro drug release from o/w microemulsions with low surfactant content.
PubMed: Percutaneous absorption of vanilloids: in vivo and in vitro studies.
PubMed: Percutaneous absorption and skin decontamination of PCBs: in vitro studies with human skin and in vivo studies in the rhesus monkey.
PubMed: Comparison of percutaneous absorption of fragrances by humans and monkeys.
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