rebaudioside D, 63279-13-0

Supplier Sponsors

Best of Chemicals Supplier
Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services.
BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies.
Email:	Marketing
US Email:	Marketing
Email:	Sales
US Email:	Sales
Voice: 1-631-485-4226
Fax: 1-631-614-7828
US Voice: 1-631-485-4226
US Fax: 1-631-614-7828
Europe	44-203-286-1088
Facebook
Twitter
Linkedin
Blog
Get the App!
CODE105344 CODE105344
Product(s):
63279-13-0 Rebaudioside D

Chemical sources Association Inc

Exchange of knowledge
Need This Item for Flavor? You can contact the Chemical Sources Association.
Events
Links
CODE105344 CODE105344
Product(s):

CAS Number:	63279-13-0	3D/inchi
FDA UNII:	1SU114WXBX
Nikkaji Web:	J20.437D
MDL:	MFCD11113790
XlogP3-AA:	-4.40 (est)
Molecular Weight:	1129.16520000
Formula:	C50 H80 O28
NMR Predictor:	Predict (works with chrome, Edge or firefox)
EFSA/JECFA Comments:
FEMA GRAS 29 : Rebaudioside D ≥95%; Total other steviol glycosides <3.5%

Category:sweeteners, flavor enhancers

US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:

Google Scholar:	Search
Google Books:	Search
Google Scholar: with word "volatile"	Search
Google Scholar: with word "flavor"	Search
Google Scholar: with word "odor"	Search
Google Patents:	Search
US Patents:	Search
EU Patents:	Search
Pubchem Patents:	Search
PubMed:	Search
NCBI:	Search
	FDA/DG SANTE Petitions, Reviews, Notices:
GRN 456	Rebaudioside D purified from the leaves of Stevia rebaudiana (Bertoni) Bertoni (rebaudioside D) View - notice PDF
GRN 548	High purity rebaudioside D View - notice PDF
GRN 715	Rebaudioside D View - notice PDF
GRN 764	Rebaudioside D View PDF
FEMA Number:	4921 rebaudioside D
FDA:	No longer provide for the use of these seven synthetic flavoring substances

Physical Properties:

Assay:	95.00 to 100.00
Food Chemicals Codex Listed:	No
Flash Point:	32.00 °F. TCC ( 0.00 °C. ) (est)
logP (o/w):	-3.377 (est)

Organoleptic Properties:

Odor and/or flavor descriptions from others (if found).

Cosmetic Information:

None found

Suppliers:

Alfa Biotechnology

For experimental / research use only.

Rebaudioside D 98%

BOC Sciences

For experimental / research use only.

Rebaudioside D

Carbosynth

For experimental / research use only.

Rebaudioside D

Layn Natural ingredients

For experimental / research use only.

Rebaudioside D analytical standard

Chemical Sources Association

Need This Item for Flavor/Food?: You can contact the Chemical Sources Association

Safety Information:


Hazards identification

Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements

Pictogram

Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in Use Information:

Category:
sweeteners, flavor enhancers
Recommendation for rebaudioside D usage levels up to:
	not for fragrance use.

Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 29
Click here to view publication 29
		average usual ppm	average maximum ppm
baked goods:		15.00000	32.50000
beverages(nonalcoholic):		15.00000	32.50000
beverages(alcoholic):		15.00000	32.50000
breakfast cereal:		15.00000	32.50000
cheese:		-	-
chewing gum:		200.00000	325.00000
condiments / relishes:		15.00000	32.50000
confectionery froastings:		15.00000	32.50000
egg products:		-	-
fats / oils:		-	-
fish products:		-	-
frozen dairy:		15.00000	32.50000
fruit ices:		15.00000	32.50000
gelatins / puddings:		15.00000	32.50000
granulated sugar:		-	-
gravies:		-	-
hard candy:		15.00000	32.50000
imitation dairy:		15.00000	32.50000
instant coffee / tea:		15.00000	32.50000
jams / jellies:		15.00000	32.50000
meat products:		-	-
milk products:		15.00000	32.50000
nut products:		15.00000	32.50000
other grains:		15.00000	32.50000
poultry:		-	-
processed fruits:		15.00000	32.50000
processed vegetables:		-	-
reconstituted vegetables:		-	-
seasonings / flavors:		15.00000	32.50000
snack foods:		15.00000	32.50000
soft candy:		15.00000	32.50000
soups:		15.00000	32.50000
sugar substitutes:		-	-
sweet sauces:		15.00000	32.50000

Safety References:

AIDS Citations:Search

Cancer Citations:Search

Toxicology Citations:Search

EPA ACToR:Toxicology Data

EPA Substance Registry Services (SRS):Registry

Laboratory Chemical Safety Summary :71773169

National Institute of Allergy and Infectious Diseases:Data

WGK Germany:3

Chemidplus:0063279130

References:

NIST Chemistry WebBook:	Search Inchi
Pubchem (cid):	71773169
Pubchem (sid):	172648804

Other Information:

(IUPAC):	Atomic Weights of the Elements 2011 (pdf)
Videos:	The Periodic Table of Videos
tgsc:	Atomic Weights use for this web site
(IUPAC):	Periodic Table of the Elements
CHEBI:	View
CHEMBL:	View
HMDB (The Human Metabolome Database):	HMDB34948
FooDB:	FDB013541
FDA Listing of Food Additive Status:	View
VCF-Online:	VCF Volatile Compounds in Food
ChemSpider:	View

Potential Blenders and core components note

None Found

Potential Uses:

None Found

Occurrence (nature, food, other):note

stevia rebaudiana
Search Trop Picture

Synonyms:

	KAUR-16-EN-18-oic acid, 13-((o-beta-D-glucopyranosyl-(1->2)-O-(beta-D-glucopyranosyl-(1->3))-beta-D-glucopyranosyl)oxy)-, 2-o-beta-D-glucopyranosyl-beta-D-glucopyranosyl ester, (4alpha)-
	rebaudioside D purified from the leaves of stevia rebaudiana (bertoni) bertoni (rebaudioside D)

Articles:

PubMed:Isolation and Characterization of a Novel Rebaudioside M Isomer from a Bioconversion Reaction of Rebaudioside A and NMR Comparison Studies of Rebaudioside M Isolated from Stevia rebaudiana Bertoni and Stevia rebaudiana Morita.

PubMed:Rebaudioside A and Rebaudioside D bitterness do not covary with Acesulfame K bitterness or polymorphisms in TAS2R9 and TAS2R31.

PubMed:Hydrogenation of the exocyclic olefinic bond at C-16/C-17 position of ent-kaurane diterpene glycosides of Stevia rebaudiana using various catalysts.

PubMed:Metabolism and toxicity studies supporting the safety of rebaudioside D.

PubMed:Simultaneous analysis of steviol and steviol glycosides by liquid chromatography with ultraviolet detection on a mixed-mode column: application to Stevia plant material and Stevia-containing dietary supplements.

PubMed:Catalytic Hydrogenation of the Sweet Principles of Stevia rebaudiana, Rebaudioside B, Rebaudioside C, and Rebaudioside D and Sensory Evaluation of Their Reduced Derivatives.

Notes:

Constit. of Stevia rebaudiana (stevia)