EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes

para-cresyl alcohol
4-methylbenzyl alcohol

Supplier Sponsors

CAS Number: 589-18-4Picture of molecule3D/inchi
Other(deleted CASRN):185532-77-8
ECHA EINECS - REACH Pre-Reg:209-639-1
Nikkaji Web:J28.550A
Beilstein Number:1856550
XlogP3:1.60 (est)
Molecular Weight:122.16690000
Formula:C8 H10 O
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:cosmetic, flavor and fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
JECFA Food Flavoring:2065 4-methylbenzyl alcohol
FEMA Number:4624 4-methylbenzyl alcohol
FDA:No longer provide for the use of these seven synthetic flavoring substances
Physical Properties:
Appearance:white solid (est)
Assay: 97.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 61.00 to 62.00 °C. @ 760.00 mm Hg
Boiling Point: 217.00 to 218.00 °C. @ 760.00 mm Hg
Boiling Point: 116.00 to 118.00 °C. @ 20.00 mm Hg
Acid Value: 1.00 max. KOH/g
Vapor Pressure:0.073000 mmHg @ 25.00 °C.
Flash Point: 221.00 °F. TCC ( 105.00 °C. )
logP (o/w): 1.580
Soluble in:
 water, 7710 mg/L @ 25 °C (exp)
Insoluble in:
Organoleptic Properties:
Odor Strength:low
Odor Description:at 100.00 %. mild floral
Odor and/or flavor descriptions from others (if found).
Cosmetic Information:
CosIng:cosmetic data2
CosIng:cosmetic data
Cosmetic Uses: fragrance
perfuming agents
skin conditioning
BOC Sciences
For experimental / research use only.
4-methylbenzyl alcohol 98%
Tolyl Alcohol Crystals
Inoue Perfumery
Penta International
Penta International
Santa Cruz Biotechnology
For experimental / research use only.
4-Methylbenzyl alcohol
Sigma-Aldrich: Aldrich
For experimental / research use only.
4-Methylbenzyl alcohol 98%
For experimental / research use only.
4-Methylbenzyl Alcohol >99.0%(GC)
Safety Information:
Preferred SDS: View
European information :
Most important hazard(s):
Xi - Irritant
R 36/37/38 - Irritating to eyes, respiratory system, and skin.
S 02 - Keep out of the reach of children.
S 24/25 - Avoid contact with skin and eyes.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 36/37/39 - Wear suitable clothing, gloves and eye/face protection.
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50 3900 mg/kg
Food and Chemical Toxicology. Vol. 20, Pg. 839, 1982.

oral-mouse LD50 1400 mg/kg
Arzneimittel-Forschung. Drug Research. Vol. 12, Pg. 347, 1962.

intraperitoneal-mouse LD50 324 mg/kg
Yakugaku Zasshi. Journal of Pharmacy. Vol. 104, Pg. 793, 1984.

Dermal Toxicity:
skin-rabbit LD50 > 5000 mg/kg
Food and Chemical Toxicology. Vol. 20, Pg. 839, 1982.

Inhalation Toxicity:
Not determined
Safety in Use Information:
cosmetic, flavor and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
IFRA Critical Effect:
Dermal sensitization and systemic toxicity
 View the IFRA Standard
View IFRA Standards Library for complete information.
Please review Amendment 49 IFRA documentation for complete information.
Category 1: Products applied to the lips
0.048 %
Category 2: Products applied to the axillae
0.048 %
Category 3: Products applied to the face/body using fingertips
0.048 %
Category 4: Products related to fine fragrance
1.50 %
 Category 5: Products applied to the face and body using the hands (palms), primarily leave-on
Category 5A: Body lotion products applied to the body using the hands (palms), primarily leave-on
0.64 %
Category 5B: Face moisturizer products applied to the face using the hands (palms), primarily leave-on
0.048 %
Category 5C: Hand cream products applied to the hands using the hands (palms), primarily leave-on
0.048 %
Category 5D: Baby Creams, baby Oils and baby talc
0.016 %
Category 6: Products with oral and lip exposure
0.048 %
 Category 7: Products applied to the hair with some hand contact
Category 7A: Rinse-off products applied to the hair with some hand contact
0.048 %
Category 7B: Leave-on products applied to the hair with some hand contact
0.048 %
Category 8: Products with significant anogenital exposure
0.016 %
Category 9: Products with body and hand exposure, primarily rinse off
0.53 %
 Category 10: Household care products with mostly hand contact
Category 10A: Household care excluding aerosol products (excluding aerosol/spray products)
0.53 %
Category 10B: Household aerosol/spray products
0.048 %
 Category 11: Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate
Category 11A: Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
0.016 %
Category 11B: Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
0.016 %
Category 12: Products not intended for direct skin contact, minimal or insignificant transfer to skin
No Restriction

Due to the possible ingestion of small amounts of fragrance ingredients from their use in products in Categories 1 and 6, materials must not only comply with IFRA Standards but must also be recognized as safe as a flavoring ingredient as defined by the IOFI Code of Practice ( For more details see chapter 1 of the Guidance for the use of IFRA Standards.

Structure Class: I
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 24
Click here to view publication 24
 average usual ppmaverage maximum ppm
baked goods: --
beverages(nonalcoholic): 0.010000.10000
beverages(alcoholic): 0.020000.50000
breakfast cereal: --
cheese: --
chewing gum: --
condiments / relishes: --
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: --
fruit ices: 0.010000.50000
gelatins / puddings: --
granulated sugar: --
gravies: --
hard candy: --
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --
Safety References:
EPI System: View
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):589-18-4
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :11505
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:2
EPA/NOAA CAMEO:hazardous materials
RTECS:DO9370000 for cas# 589-18-4
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):11505
Pubchem (sid):134976538
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):View
Metabolomics Database:Search
UM BBD:Search
KEGG (GenomeNet):C06757
HMDB (The Human Metabolome Database):HMDB41609
Export Tariff Code:2906.29.6000
VCF-Online:VCF Volatile Compounds in Food
FAO:4-Methylbenzyl alcohol
Potential Blenders and core components note
None Found
Potential Uses:
None Found
Occurrence (nature, food, other):note
 artemisia selengensis turcz.
Search Trop Picture
 benzenemethanol, 4-methyl-
p-cresyl alcohol
4-(hydroxymethyl) toluene
4-methyl benzyl alcohol
p-methyl benzyl alcohol
para-methyl benzyl alcohol
p-methyl benzyl alcohol powder
4-methylbenzyl alcohol
p-methylbenzyl alcohol
para-methylbenzyl alcohol
p-tolyl alcohol
para-tolyl alcohol
a pulmonary metabolite of para-xylene. Cosmetic and flavouring ingredient [CCD]
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