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bellidifolin
9H-xanthen-9-one, 1,5,8-trihydroxy-3-methoxy- (9CI)

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Name:1,5,8-trihydroxy-3-methoxyxanthen-9-one
CAS Number: 2798-25-6Picture of molecule3D/inchi
FDA UNII: Search
Nikkaji Web:J83.278B
Beilstein Number:0288441
XlogP3-AA:2.40 (est)
Molecular Weight:274.22890000
Formula:C14 H10 O6
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:natural substances and extractives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Soluble in:
 water, 1.819 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
Alfa Biotechnology
For experimental / research use only.
Bellidifolin 98%
BOC Sciences
For experimental / research use only.
Bellidifolin 98.5%
Odor: characteristic
Use: Bellidifolin is a xanthone that can be isolated from the plants of Gentiana sp
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
natural substances and extractives
Recommendation for bellidifolin usage levels up to:
 not for fragrance use.
 
Recommendation for bellidifolin flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :5281623
National Institute of Allergy and Infectious Diseases:Data
1,5,8-trihydroxy-3-methoxyxanthen-9-one
Chemidplus:0002798256
 
References:
 1,5,8-trihydroxy-3-methoxyxanthen-9-one
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):5281623
Pubchem (sid):135037529
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
CHEMBL:View
KEGG (GenomeNet):C10053
HMDB (The Human Metabolome Database):Search
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 swertia japonica
Search Trop Picture
 swertia mussotii
Search Trop Picture
 
Synonyms:
3-methoxy-1,5,8-trihydroxyxanthen-9-one
1,5,8-trihydroxy-3-methoxy-9H-xanthen-9-one
1,5,8-trihydroxy-3-methoxyxanthen-9-one
9H-xanthen-9-one, 1,5,8-trihydroxy-3-methoxy- (9CI)
 

Articles:

PubMed:Protective effects of bellidifolin in hypoxia-induced in pheochromocytoma cells (PC12) and underlying mechanisms.
PubMed:Chemical constituents from Swertia mussotii Franch. (Gentianaceae).
PubMed:[Isolation and identification of xanthones from Gentianella acuta].
PubMed:Determination and pharmacokinetic study of four xanthones in rat plasma after oral administration of Gentianella acuta extract by UHPLC-ESI-MS/MS.
PubMed:Two xanthones from Swertia punicea with hepatoprotective activities in vitro and in vivo.
PubMed:Inhibition of vascular smooth muscle cell proliferation by Gentiana lutea root extracts.
PubMed:Antimicrobial and antioxidant activities of Gentianella multicaulis collected on the Andean Slopes of San Juan Province, Argentina.
PubMed:Activity-guided isolation of antioxidant xanthones from Swertia chirayita (Roxb.) H. Karsten (Gentianaceae).
PubMed:Anti-diabetic effect of methylswertianin and bellidifolin from Swertia punicea Hemsl. and its potential mechanism.
PubMed:[Determination of six active components in three species of genus Swertia by HPLC multiwavelength with detection].
PubMed:Radioprotective effects of Gentianella austriaca fractions and polyphenolic constituents in human lymphocytes.
PubMed:Xanthones from Gentianella amarella ssp. acuta with acetylcholinesterase and monoamine oxidase inhibitory activities.
PubMed:[Study on chemical constituents from Swertia kauitchensis Franch].
PubMed:Chemopreventive action of xanthone derivatives on photosensitized DNA damage.
PubMed:Xanthones from Gentiana campestris as new acetylcholinesterase inhibitors.
PubMed:Xanthones from Swertia punctata.
PubMed:Bellidifolin stimulates glucose uptake in rat 1 fibroblasts and ameliorates hyperglycemia in streptozotocin (STZ)-induced diabetic rats.
PubMed:Bellidifolin: a potent hypoglycemic agent in streptozotocin (STZ)-induced diabetic rats from Swertia japonica.
PubMed:Mutagenicities of xanthone derivatives in Salmonella typhimurium TA100, TA98, TA97, and TA2637.
 
Notes:
None found
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