EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

1,2,3-trimethoxybenzene
tri-O-methylpyrogallol

Supplier Sponsors

Name:1,2,3-trimethoxybenzene
CAS Number: 634-36-6Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:211-207-2
FDA UNII: MRE1O894FG
Nikkaji Web:J122.021G
Beilstein Number:1910422
MDL:MFCD00008358
XlogP3:1.50 (est)
Molecular Weight:168.19224000
Formula:C9 H12 O3
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:flavor and fragrance agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
DG SANTE Food Flavourings:04.084 1,2,3-trimethoxybenzene
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity:1.11200 @ 25.00 °C.
Melting Point: 47.00 °C. @ 760.00 mm Hg
Boiling Point: 235.00 °C. @ 760.00 mm Hg
Vapor Pressure:0.078000 mmHg @ 25.00 °C. (est)
Flash Point:> 230.00 °F. TCC ( > 110.00 °C. )
logP (o/w): 1.530
Soluble in:
 alcohol
 water, 3096 mg/L @ 25 °C (est)
Insoluble in:
 water
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
Beijing Lys Chemicals
1,2,3-Trimethoxybenzene
BOC Sciences
For experimental / research use only.
1,2,3-Trimethoxybenzene
EMD Millipore
For experimental / research use only.
1,2,3-Trimethoxybenzene
sds
Penta International
1,2,3-TRIMETHOXYBENZENE
Santa Cruz Biotechnology
For experimental / research use only.
1,2,3-Trimethoxybenzene
Sigma-Aldrich: Aldrich
For experimental / research use only.
1,2,3-Trimethoxybenzene
sds
Synerzine
1,2,3-Trimethoxybenzene
TCI AMERICA
For experimental / research use only.
1,2,3-Trimethoxybenzene >99.0%(GC)
sds
WholeChem
1,2,3-Trimethoxybenzene
 
Safety Information:
Preferred SDS: View
European information :
Most important hazard(s):
None - None found.
S 02 - Keep out of the reach of children.
S 24/25 - Avoid contact with skin and eyes.
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
flavor and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
 
Maximised Survey-derived Daily Intakes (MSDI-EU): 0.012 (μg/capita/day)
Modified Theoretical Added Maximum Daily Intake (mTAMDI): 3200 (μg/person/day)
Threshold of Concern:1800 (μg/person/day)
Structure Class: I
 
Food categories according to Commission Regulation EC No. 1565/2000 (EC, 2000) in FGE.06 (EFSA, 2002a). According to the Industry the "normal" use is defined as the average of reported usages and "maximum use" is defined as the 95th percentile of reported usages (EFSA, 2002i).
Note: mg/kg = 0.001/1000 = 0.000001 = 1/1000000 = ppm.
 average usage mg/kgmaximum usage mg/kg
Dairy products, excluding products of category 02.0 (01.0): 3.0000015.00000
Fats and oils, and fat emulsions (type water-in-oil) (02.0): 2.0000010.00000
Edible ices, including sherbet and sorbet (03.0): 3.0000015.00000
Processed fruit (04.1): 2.0000010.00000
Processed vegetables (incl. mushrooms & fungi, roots & tubers, pulses and legumes), and nuts & seeds (04.2): --
Confectionery (05.0): 10.0000050.00000
Chewing gum (05.3): --
Cereals and cereal products, incl. flours & starches from roots & tubers, pulses & legumes, excluding bakery (06.0): 5.0000025.00000
Bakery wares (07.0): 10.0000050.00000
Meat and meat products, including poultry and game (08.0): 2.0000010.00000
Fish and fish products, including molluscs, crustaceans and echinoderms (MCE) (09.0): 2.0000010.00000
Eggs and egg products (10.0): --
Sweeteners, including honey (11.0): --
Salts, spices, soups, sauces, salads, protein products, etc. (12.0): 5.0000025.00000
Foodstuffs intended for particular nutritional uses (13.0): 10.0000050.00000
Non-alcoholic ("soft") beverages, excl. dairy products (14.1): 3.0000015.00000
Alcoholic beverages, incl. alcohol-free and low-alcoholic counterparts (14.2): 10.0000050.00000
Ready-to-eat savouries (15.0): 15.0000075.00000
Composite foods (e.g. casseroles, meat pies, mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0): 5.0000025.00000
 
Safety References:
European Food Safety Athority(EFSA):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...

European Food Safety Authority (EFSA) reference(s):

Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to Flavouring Group Evaluation 23 (FGE.23): Aliphatic, alicyclic and aromatic ethers including anisole derivatives From chemical groups 15, 16 and 26 (Commission Regulation (EC) No 1565/2000 of 18 July 2000
View page or View pdf

Flavouring Group Evaluation 59 (FGE.59): Consideration of aliphatic and aromatic ethers evaluated by JECFA (61st meeting) structurally related to aliphatic, alicyclic and aromatic ethers including anisole derivatives evaluated by EFSA in FGE.23 (2006) (Commission Regulation (EC) No 1565/2000 of 18 July 2000) - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC)
View page or View pdf

Flavouring Group Evaluation 23, Revision 1 (FGE.23Rev1): Aliphatic, alicyclic and aromatic ethers including anisole derivatives from chemical groups 15, 16, 26 and 30[1] - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food
View page or View pdf

Scientific Opinion on Flavouring Group Evaluation 23, Revision 2 (FGE.23Rev2): Aliphatic, alicyclic and aromatic ethers including anisole derivatives from chemical groups 15, 16, 22, 26 and 30
View page or View pdf

Scientific Opinion on Flavouring Group Evaluation 59, Revision 1 (FGE.59Rev1): Consideration of aliphatic and aromatic ethers evaluated by JECFA (61st meeting and 63rd meeting) structurally related to aliphatic, alicyclic and aromatic ethers including anisole derivatives evaluated by EFSA in FGE.23 Rev2 (2010)
View page or View pdf

Scientific Opinion on Flavouring Group Evaluation 23, Revision 3 (FGE.23Rev3): Aliphatic, alicyclic and aromatic ethers including anisole derivatives from chemical groups 15, 16, 22, 26 and 30
View page or View pdf

Scientific Opinion on Flavouring Group Evaluation 23, Revision 4 (FGE.23Rev4): Aliphatic, alicyclic and aromatic ethers including anisole derivatives from chemical groups 15, 16, 22, 26 and 30
View page or View pdf

EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):634-36-6
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :12462
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
1,2,3-trimethoxybenzene
Chemidplus:0000634366
 
References:
 1,2,3-trimethoxybenzene
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:634-36-6
Pubchem (cid):12462
Pubchem (sid):134977710
Pherobase:View
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
Metabolomics Database:Search
HMDB (The Human Metabolome Database):Search
FooDB:FDB011683
Export Tariff Code:2909.30.6000
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 bonito dried bonito - 3.8 mg/kg
Search PMC Picture
 tea - 20 mg/kg
Search Trop Picture
 wood smoke
Search Picture
 
Synonyms:
 benzene, 1,2,3-trimethoxy-
 benzene, trimethoxy-
 dimethoxyanisole
 methyl syringol
 methylsyringol
 pyrogallol trimethyl ether
 tri-O-methyl pyrogallol
 tri-O-methylpyrogallol
1,2,3-trimethoxy benzene
 trimethoxybenzene
3,4,5-trimethoxybenzene
1,2,3-trimethoxybenzol
 

Articles:

PubMed:The study of fingerprint characteristics of Dayi Pu-Erh tea using a fully automatic HS-SPME/GC-MS and combined chemometrics method.
PubMed:Synthesis of 3,3'-di-O-methyl ardimerin and exploration of its DNA binding properties.
PubMed:SYNTHESIS AND BIOLOGICAL ACTIVITY OF SULFUR COMPOUNDS SHOWING STRUCTURAL ANALOGY WITH COMBRETASTATIN A-4.
PubMed:Trimethoprim: kinetic and mechanistic considerations in photochemical environmental fate and AOP treatment.
PubMed:An isotropic chemical shift-chemical shift anisotropic correlation experiment using discrete magic angle turning.
PubMed:The behavior of exciplex decay processes and interplay of radiationless transition and preliminary reorganization mechanisms of electron transfer in loose and tight pairs of reactants.
PubMed:Quantitative 2D HSQC NMR determination of polymer structures by selecting suitable internal standard references.
PubMed:Thermally assisted hydrolysis and methylation of purified tannins from plants.
PubMed:An Au-catalyzed cyclialkylation of electron-rich arenes with epoxides to prepare 3-chromanols.
PubMed:Sensitivity-enhanced phase-corrected ultra-slow magic angle turning using multiple-echo data acquisition.
PubMed:Antifungal constituents of the stem bark of Bridelia retusa.
PubMed:Antioxidant activity and characterization of volatile constituents of Taheebo (Tabebuia impetiginosa Martius ex DC).
PubMed:Water soluble molecular switches of fluorescence based on the Ni(III)/Ni(II) redox change.
PubMed:Synthesis of cyclophanetetrayne complexes from bis(propargyldicobalt) dication equivalents.
PubMed:A high-resolution (13)C 3D CSA-CSA-CSA correlation experiment by means of magic angle turning.
PubMed:Measurement of 13C chemical shift tensor principal values with a magic-angle turning experiment.
PubMed:Improvements to the magic angle hopping experiment.
PubMed:Selective saturation and inversion of multiple resonances in high-resolution solid-state 13C experiments using slow spinning CP/MAS and tailored DANTE pulse sequences.
PubMed:Biotransformations of carboxylated aromatic compounds by the acetogen Clostridium thermoaceticum: generation of growth-supportive CO2 equivalents under CO2-limited conditions.
PubMed:2,4-diamino-5-benzylpyrimidines and analogues as antibacterial agents. 6. A one-step synthesis of new trimethoprim derivatives and activity analysis by molecular modeling.
 
Notes:
None found
Please share your Comments.
Email Address:
Top of Page Home
Copyright © 1980-2021 The Good Scents Company (tgsc) ™ Disclaimer Privacy Policy