EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

carvomenthol
p-menthan-2-ol

Supplier Sponsors

Name:2-methyl-5-propan-2-ylcyclohexan-1-ol
CAS Number: 499-69-4Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:207-885-4
FDA UNII: X55010FU6N
Nikkaji Web:J46.987D
CoE Number:2228
XlogP3-AA:3.00 (est)
Molecular Weight:156.26860000
Formula:C10 H20 O
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:flavor and fragrance agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
JECFA Food Flavoring:376 p-menthan-2-ol
DG SANTE Food Flavourings:02.071 p-menthan-2-ol
FEMA Number:3562 p-menthan-2-ol
FDA:No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF):499-69-4 ; CARVOMENTHOL
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity:0.88700 to 0.89300 @ 25.00 °C.
Pounds per Gallon - (est).: 7.381 to 7.431
Refractive Index:1.46200 to 1.46300 @ 20.00 °C.
Boiling Point: 222.00 °C. @ 760.00 mm Hg
Vapor Pressure:0.021000 mmHg @ 25.00 °C. (est)
Flash Point: 188.00 °F. TCC ( 86.67 °C. )
logP (o/w): 3.216 (est)
Soluble in:
 alcohol
 water, 298.3 mg/L @ 25 °C (est)
Insoluble in:
 water
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
Axsyn
For experimental / research use only.
Cyclohexanol,2-methyl-5-(1-methylethyl)-, (1R,2R,5R)-rel-
BOC Sciences
For experimental / research use only.
Carvomenthol
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
flavor and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
 
Maximised Survey-derived Daily Intakes (MSDI-EU): 0.012 (μg/capita/day)
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 11
Click here to view publication 11
 average usual ppmaverage maximum ppm
baked goods: -14.80000
beverages(nonalcoholic): -2.20000
beverages(alcoholic): -4.00000
breakfast cereal: --
cheese: --
chewing gum: --
condiments / relishes: --
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: -7.60000
fruit ices: --
gelatins / puddings: -4.10000
granulated sugar: --
gravies: --
hard candy: --
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: -14.80000
soups: --
sugar substitutes: --
sweet sauces: --
 
Safety References:
European Food Safety Athority(EFSA):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...

European Food Safety Authority (EFSA) reference(s):

Flavouring Group Evaluation 9, Revision 1: (FGE.09 Rev1)[1] - Secondary alicyclic saturated and unsaturated alcohols, ketones and esters containing secondary alicyclic alcohols from chemical groups 8 and 30, and an ester of a phenol carboxylic acid from chemical group 25 - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food
View page or View pdf

Flavouring Group Evaluation 9, Revision 2 (FGE.09Rev2): Secondary alicyclic saturated and unsaturated alcohols, ketones and esters containing secondary alicyclic alcohols from chemical group 8 and 30, and an ester of a phenol derivative from chemical group 25
View page or View pdf

EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :86850
National Institute of Allergy and Infectious Diseases:Data
2-methyl-5-propan-2-ylcyclohexan-1-ol
Chemidplus:0000499694
 
References:
 2-methyl-5-propan-2-ylcyclohexan-1-ol
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:499-69-4
Pubchem (cid):86850
Pubchem (sid):135057970
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):View
HMDB (The Human Metabolome Database):HMDB37223
FooDB:FDB016230
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 grapefruit oil
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 lemon oil
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 mandarin oil
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 orange oil
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 peppermint oil
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Synonyms:
 cyclohexanol, 2-methyl-5-(1-methylethyl)-
 hexahydrocarvacrol
p-menthan-2-ol
para-menthan-2-ol
p-menthane-2-ol
para-menthane-2-ol
1-methyl-4-isopropyl-2-cyclohexanol
2-methyl-5-isopropylcyclohexanol
2-methyl-5-propan-2-ylcyclohexan-1-ol
5-isopropyl-2-methylcyclohexanol
3-isopropyl-6-methyl cyclohexanol
3-isopropyl-6-methylcyclohexanol
(1alpha,2beta,5alpha)-5-(isopropyl)-2-methyl cyclohexan-1-ol
(1R-(1a,2a,5a))-5-(isopropyl)-2-methylcyclohexan-1-ol
[1R-(1a,2a,5a)]-5-(isopropyl)-2-methylcyclohexan-1-ol
 

Articles:

PubMed:Chemical stability of extra-virgin olive oil added with oregano essential oil.
PubMed:Evaluation of certain food additive and contaminants.
PubMed:Hemisynthesis of dihydroumbellulols from umbellulone: new cooling compounds.
PubMed:Terpene conjugates of diaminedichloridoplatinum(II) complexes: antiproliferative effects in HL-60 leukemia, 518A2 melanoma, and HT-29 colon cancer cells.
PubMed:Effect of ion-pairing and enhancers on scutellarin skin permeability.
PubMed:Transdermal drug delivery systems of a beta blocker: design, in vitro, and in vivo characterization.
PubMed:GC analysis of essential oils in the rumen fluid after incubation of Thuja orientalis twigs in the Rusitec system.
PubMed:Purification and characterization of a Baeyer-Villiger mono-oxygenase from Rhodococcus erythropolis DCL14 involved in three different monocyclic monoterpene degradation pathways.
PubMed:Percutaneous penetration of fluorescein isothiocyanate-dextrans and the mechanism for enhancement effect of enhancers on the intercellular penetration.
PubMed:Mucosecretolytic effect of 1-methyl-4-(2-hydroxy-isopropyl)-cyclohex-1,2-en-6-ol (sobrerol) in the rabbit.
 
Notes:
Flavouring ingredient
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