EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

calcium phosphate basic
tricalcium phosphate

Supplier Sponsors

Name:tricalcium diphosphate
CAS Number: 7758-87-4Picture of molecule3D/inchi
Other(deleted CASRN):1160697-13-1
ECHA EINECS - REACH Pre-Reg:231-840-8
FDA UNII: K4C08XP666
MDL:MFCD00015984
Molecular Weight:310.17512400
Formula:Ca3 O8 P2
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:flour maturing and bleaching, dough conditionings, acidity regulators
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 FDA/DG SANTE Petitions, Reviews, Notices:
EU SANCO Calcium phosphates View - review
JECFA Food Additive: Tricalcium Phosphate
GSFA Codex: Tricalcium phosphate (341(iii))
FEMA Number:3081 tricalcium phosphate
FDA:No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF):7758-87-4 ; CALCIUM PHOSPHATE, TRIBASIC
FDA Regulation:
FDA PART 137 -- CEREAL FLOURS AND RELATED PRODUCTS
Subpart B--Requirements for Specific Standardized Cereal Flours and Related Products
Sec. 137.105 Flour.


FDA PART 169 -- FOOD DRESSINGS AND FLAVORINGS
Subpart B--Requirements for Specific Standardized Food Dressings and Flavorings
Sec. 169.179 Vanilla powder.


FDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS
Subpart C--Substances for Use as Components of Coatings
Sec. 175.300 Resinous and polymeric coatings.


FDA PART 182 -- SUBSTANCES GENERALLY RECOGNIZED AS SAFE
Subpart B--Multiple Purpose GRAS Food Substances
Sec. 182.1217 Calcium phosphate.


FDA PART 182 -- SUBSTANCES GENERALLY RECOGNIZED AS SAFE
Subpart I--Nutrients
Sec. 182.8217 Calcium phosphate.
 
Physical Properties:
Appearance:white powder (est)
Assay: 75.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 158.00 °C. @ 760.00 mm Hg
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
logP (o/w): -2.150
Insoluble in:
 alcohol
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: abrasives
anticaking agents
fragrance
opacifying agents
oral care agents
 
Suppliers:
American Elements
Calcium Phosphate 99%
Odor: characteristic
Use: Calcium Phosphate is generally immediately available in most volumes. High purity, submicron and nanopowder forms may be considered. American Elements produces to many standard grades when applicable, including Mil Spec (military grade); ACS, Reagent and Technical Grade; Food, Agricultural and Pharmaceutical Grade; Optical Grade, USP and EP/BP (European Pharmacopoeia/British Pharmacopoeia) and follows applicable ASTM testing standards.
American International Chemical, LLC.
TRICALCIUM PHOSPHATE ANHYDROUS MICRONIZED FCC
BOC Sciences
For experimental / research use only.
Calcium Phosphate Tribasic, Powder, Reagent 95%
Charkit Chemical
TRICALCIUM PHOSPHATE
Glentham Life Sciences
Calcium orthophosphate
Graham Chemical
Tricalcium Phosphate
Indis NV
For experimental / research use only.
Tri-Calcium Phosphate
Kraft Chemical
Tricalcium Phosphate
Penta International
CALCIUM PHOSPHATE TRIBASIC FCC
Prinova
Tricalcium Phosphate FCC, E341, NF
Silver Fern Chemical
Tricalcium Phosphate
Odor: characteristic
Use: Tricalcium Phosphate is used in ceramics, polishing powders, animal feed, certain medicines, fertilizers, meat tenderizers, and food additives. It is often favored for its anti-caking properties.
Zhong Ya Chemical
Calcium Phosphate, Tri
 
Safety Information:
European information :
Most important hazard(s):
None - None found.
S 02 - Keep out of the reach of children.
S 22 - Do not breath dust.
S 24/25 - Avoid contact with skin and eyes.
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
flour maturing and bleaching, dough conditionings, acidity regulators
Recommendation for calcium phosphate basic usage levels up to:
 not for fragrance use.
 
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
Click here to view publication 3
 average usual ppmaverage maximum ppm
baked goods: -80.00000
beverages(nonalcoholic): -1000.00000
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: --
condiments / relishes: -540.00000
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: -46.00000
fruit ices: -46.00000
gelatins / puddings: -700.00000
granulated sugar: --
gravies: --
hard candy: 50.0000060.00000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: -360.00000
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --
 
Safety References:
European Food Safety Authority (EFSA) reference(s):

Assessment of one published review on health risks associated with phosphate additives in food
View page or View pdf

ClinicalTrials.gov:search
Daily Med:search
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):7758-87-4
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :24456
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
tricalcium diphosphate
Chemidplus:0007758874
EPA/NOAA CAMEO:hazardous materials
 
References:
 tricalcium diphosphate
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:7758-87-4
Pubchem (cid):24456
Pubchem (sid):134989993
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):View
FDA Indirect Additives used in Food Contact Substances:View
CHEBI:View
CHEMBL:View
KEGG (GenomeNet):C08136
HMDB (The Human Metabolome Database):Search
FooDB:FDB013351
FDA Listing of Food Additive Status:View
ChemSpider:View
Wikipedia:View
Formulations/Preparations:
•grade: it is about 96% pure, usually containing an excess of calcium oxide. •grades: granular; technical; chemically pure: a grade designation signifying a minimum of impurities, but not 100% purity; national formulary; pure precipitated; food chemicals codex.
 
Potential Blenders and core components note
None Found
 
Potential Uses:
 abrasives
 opacifying agents
 oral care agents
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 bonarka
 calcigenol simple
 calcium diorthophosphate
 calcium diphosphate
 calcium orthophosphate
tertiary calcium phosphate
 calcium phosphate basic
 calcium phosphate hydroxide
 calcium phosphate tribasic
 calcium phosphate tribasic anhydrous
 calcium phosphate tribasic FCC
 calcium phosphate, tri
 posture
 synthos
a-TCP
 tri-calcium (ortho)phosphate
a-tri-calcium phosphate
 tribasic calcium phosphate
 tricalcium bis(orthophosphate)
 tricalcium bis(phosphate)
 tricalcium diphosphate
 tricalcium orthophosphate
 tricalcium phosphate
a-tricalcium phosphate
beta-tricalcium phosphate
 tricalcium phosphate (food grade)
 tricalcium phosphate anhydrous granular NF FCC
 tricalcium phosphate anhydrous powder FCC
 tricalcium phosphate anhydrous powder FCC N-2
 tricalcium phosphate FCC, E341, NF
 

Articles:

PubMed:Effect of drying treatments and storage stability on quality characteristics of bael powder.
PubMed:Influence of micellar calcium and phosphorus on rennet coagulation properties of cows milk.
PubMed:Advances in regenerative orthopedics.
PubMed:Luteibacter rhizovicinus MIMR1 promotes root development in barley (Hordeum vulgare L.) under laboratory conditions.
PubMed:Percutaneous injection of augment injectable bone graft (rhPDGF-BB and β-tricalcium phosphate [β-TCP]/bovine type I collagen matrix) increases vertebral bone mineral density in geriatric female baboons.
PubMed:Perivascular stem cells: a prospectively purified mesenchymal stem cell population for bone tissue engineering.
PubMed:Effect of salt on survival and P-solubilization potential of phosphate solubilizing microorganisms from salt affected soils.
PubMed:Current application of β-tricalcium phosphate composites in orthopaedics.
PubMed:Complications of bioabsorbable suture anchors in the shoulder.
PubMed:Controlling the bleeding of carmine colorant in crabstick.
PubMed:The effects of maternal exposure to food additive E341 (tricalcium phosphate) on foetal development of rats.
PubMed:Self-hardening calcium deficient hydroxyapatite/gelatine foams for bone regeneration.
PubMed:General route for the assembly of functional inorganic capsules.
PubMed:Radioactivity contents in dicalcium phosphate and the potential radiological risk to human populations.
PubMed:Locally applied TCP inhibits tumor growth via possible activation of macrophages.
PubMed:The health benefits of calcium citrate malate: a review of the supporting science.
PubMed:New composite endpoints to assess efficacy in periodontal therapy clinical trials.
PubMed:Absorption of calcium from milks enriched with fructo-oligosaccharides, caseinophosphopeptides, tricalcium phosphate, and milk solids.
PubMed:Calcium bioavailability of calcium carbonate fortified soymilk is equivalent to cow's milk in young women.
PubMed:Lower dose of rhBMP-2 achieves spine fusion when combined with an osteoconductive bulking agent in non-human primates.
PubMed:Calcium fortification systems differ in bioavailability.
PubMed:Dental devices; reclassification of tricalcium phosphate granules and classification of other bone grafting material for dental bone repair. Final rule.
PubMed:Osteogenic protein-1 for long bone nonunion: an evidence-based analysis.
PubMed:Hyperphosphatemia in dialysis patients: is there a role for focused counseling?
PubMed:The effects of sustained delivery of diosgenin on the adrenal gland of female rats.
PubMed:Acute effect of high-calcium milk with or without additional magnesium, or calcium phosphate on parathyroid hormone and biochemical markers of bone resorption.
PubMed:Soil solid-phase controls lead activity in soil solution.
PubMed:Fate of salmonellae in calcium-supplemented orange juice at refrigeration temperature.
PubMed:Survival of salmonellae in pasteurized, refrigerated calcium-fortified orange juice.
PubMed:Soy molasses as fermentation substrate for production of butanol using Clostridium beijerinckii BA101.
PubMed:Controlled release of manganese into water from coated experimental fertilizers: laboratory characterization.
PubMed:Lessening dental erosive potential by product modification.
PubMed:Bioceramic implantation in the intermandibular space in bilateral rostral mandibulectomy of the dog.
PubMed:Solubility of calcium salts and carrageenan used in infant formulas did not influence calcium absorption in rats.
PubMed:The effect of supracrestal tricalcium phosphate ceramic-microfibrillar collagen grafting on postsurgical soft tissue levels.
PubMed:[Experimental study on the cariostatic effect of bone meal and tricalcium phosphate in the hamster].
 
Notes:
a form of tricalcium phosphate are used as bioceramic bone replacement material; apatitic tricalcium phosphate ca9(hpo4)(po4)5(oh) is the calcium orthophosphate leading to beta tricalcium phosphate ca3(po4)2 (b-tcp).
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