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lycopene
tomato lycopene

Sponsors

Name:(6E,8E,10E,12E,14E,16E,18E,20E,22E,24E,26E)-2,6,10,14,19,23,27,31-octamethyldotriaconta-2,6,8,10,12,14,16,18,20,22,24,26,30-tridecaene
CAS Number: 502-65-8Picture of molecule3D/inchi
Other:25453-98-9
ECHA EINECS - REACH Pre-Reg:207-949-1
FDA UNII:SB0N2N0WV6
Nikkaji Web:J6.206E
MDL:MFCD00017350
XlogP3-AA:15.60 (est)
Molecular Weight:536.88632000
Formula:C40 H56
NMR Predictor:Predict (works with chrome or firefox)
Category:color agents, nutrient supplements
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 FDA/DG SANTE Petitions, Reviews, Notices:
GRN 299 Lycopene from Escherichia coli expressing lycopene biosynthetic enzymes View-notice PDF
GRN 119 Synthetic lycopene View-notice PDF
GRN 156 Tomato lycopene extract 6 percent, tomato lycopene extract 1.5 percent, and crystallized tomato lycopene extract View-notice PDF
GRN 173 Lycopene from Blakeslea trispora View-notice PDF
EU SANCO Lycopene View-review
GRN 185 Concentrated tomato lycopene extract View-notice PDF
JECFA Food Additive: Lycopene (Synthetic)

Lycopene from Blakeslea trispora

Lycopene extract from tomato
GSFA Codex: Lycopene (synthetic) (160d(i))

Lycopene, Blakeslea trispora (160d(iii))

Lycopene, tomato (160d(ii))
DG SANTE Food Additives:lycopene
FEMA Number:4110 tomato lycopene
FDA:No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm: TOMATO LYCOPENE
FDA Regulation:
FDA PART 73 -- LISTING OF COLOR ADDITIVES EXEMPT FROM CERTIFICATION
Subpart A--Foods
Sec. 73.585 Tomato lycopene extract; tomato lycopene concentrate.
 
Physical Properties:
Appearance:red crystalline powder (est)
Assay: 96.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 174.00 to 175.00 °C. @ 760.00 mm Hg
Boiling Point: 660.90 °C. @ 760.00 mm Hg (est)
Flash Point:> 200.00 °F. TCC ( > 93.33 °C. )
logP (o/w): 15.190 (est)
Shelf Life: 8.00 month(s) or longer if stored properly.
Storage:store under nitrogen.
Storage:refrigerate in tightly sealed containers. store under nitrogen.
Soluble in:
 chloroform
 water, 1.037e-013 mg/L @ 25 °C (est)
Insoluble in:
 water
 
Organoleptic Properties:
Odor Strength:medium ,
recommend smelling in a 1.00 % solution or less
Odor Description:at 100.00 %. balsam oriental
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data2
CosIng:cosmetic data
Cosmetic Uses: antioxidants
cosmetic colorants
 
Suppliers:
Allied Biotech
Lycotene 10% FT
Flavor: characteristic
is an oil in water emulsion of Lycopene , specifically developed for water based applications to impart a reddish shade to food applications.
Allied Biotech
Lycotene 10% WSC
Flavor: characteristic
is a powdered formulation of lycopene providing a range of red shades for water based applications.
Allied Biotech
Lycotene 20% OS
Flavor: characteristic
is a suspension of lycopene in oil. This formulation is the most concentrated form of the product in the market and imparts a reddish shade for oil based products.
Allied Biotech
Lycotene 20% TG
Flavor: characteristic
is a Tablet Grade version of lycopene being used in multivitamins and other dietary supplements.
Atlantic Chemicals
Lycopene
AuNutra® Industries
Lycopene P.E.
BASF
Lycopene
BASF
LycoVit®
BOC Sciences
For experimental / research use only.
Lycopene
Changsha Organic Herb
Tomato Extract Lycopene
DSM Nutritional
redivivo® Lycopene
ExtraSynthese
For experimental / research use only.
Lycopene UV ≥98%
Farbest-Tallman Foods
Natural Lycopene 10% DC /Gelatin-Free
Flavor: bland
This product is used as a nutrient for tablet or hard-shell capsule preparations.
Farbest-Tallman Foods
Natural Lycopene 10% Oil Dispersion
Flavor: bland
This product can be used in supplement applications including soft gel capsules.
Farbest-Tallman Foods
Natural Lycopene 5% DC /Gelatin-Free
Flavor: bland
This product is used as a nutrient for tablet or hard-shell capsule preparations.
Jarchem Industries
Jarchem® Jarcopene
Odor: characteristic
Use: A natural source of lycopene derived from tomatoes.
Maypro Industries
Lycopene
Pangaea Sciences
Lycopene
Penta International
LYCOPENE POWDER EXTRACT 5%, Kosher
Risun Ingredients
Lycopene 10%,20% HPLC
Sigma-Aldrich: Sigma
For experimental / research use only.
Lycopene ≥90%, from tomato
Sinoway Industrial
For experimental / research use only.
Lycopene
Synthite Industries
Lycopene
E-books and Brochures
TRI-K Industries
HydroPom
Odor: characteristic
Use: Lycopene is a molecule belonging to the carotenoid family of natural pigments produced by plants and some microorganisms that support photosynthesis and protect the plant from the hazardous effects of sun exposure. On skin, lycopene acts as a powerful antioxidant - inactivating siglet oxygen and peroxide radicals. It is much more effective than both β-carotene and tocopherol.
WILD Flavors
Lycopene
Flavor: taste
Lycopene is a powerful antioxidant, serving to reduce free radical activity throughout the body and helping to maintain overall well-being.
 
Safety Information:
Preferred SDS: View
European information :
Most important hazard(s):
None - None found.
S 02 - Keep out of the reach of children.
S 22 - Do not breath dust.
S 24/25 - Avoid contact with skin and eyes.
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-mouse LD50 > 3000 mg/kg
(Milani et al., 1970)

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category: color agents, nutrient supplements
Recommendation for lycopene usage levels up to:
 not for fragrance use.
 
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 22
 average usual ppmaverage maximum ppm
baked goods: --
beverages(nonalcoholic): 2.0000020.00000
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: --
condiments / relishes: --
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: --
fruit ices: --
gelatins / puddings: --
granulated sugar: --
gravies: --
hard candy: --
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --
 
Safety References:
European Food Safety Authority (EFSA) reference(s):

Statement on the divergence between the risk assessment of lycopene by EFSA and the Joint FAO/WHO Expert Committee on Food Additives (JECFA)
View page or View pdf

Revised exposure assessment for lycopene as a food colour
View page or View pdf

Use of Lycopene as a food colour [1] - Scientific Opinion of the Panel on Food additives, Flavourings, Processing Aids and Materials in Contact with Food
View page or View pdf

Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to an application on the use of alpha-tocopherol containing oil suspensions and cold water dispersible forms of lycopene from Blakeslea trispora as a food colour
View page or View pdf

Statement on the post-marketing monitoring of the use of lycopene
View page or View pdf

Scientific Opinion on the substantiation of a health claim related to “L-tug lycopene” and reduction of blood LDL-cholesterol pursuant to Article 14 of Regulation (EC) No 1924/2006
View page or View pdf

Extension of use of lycopene (E 160d) to certain meat preparations, meat products and fruit and vegetable preparations
View page or View pdf

EPI System: View
ClinicalTrials.gov:search
Daily Med:search
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
Env. Mutagen Info. Center:Search
NLM Developmental and Reproductive Toxicity:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :446925
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
(6E,8E,10E,12E,14E,16E,18E,20E,22E,24E,26E)-2,6,10,14,19,23,27,31-octamethyldotriaconta-2,6,8,10,12,14,16,18,20,22,24,26,30-tridecaene
Chemidplus:0000502658
 
References:
 (6E,8E,10E,12E,14E,16E,18E,20E,22E,24E,26E)-2,6,10,14,19,23,27,31-octamethyldotriaconta-2,6,8,10,12,14,16,18,20,22,24,26,30-tridecaene
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):446925
Pubchem (sid):135023100
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2009
(IUPAC):Atomic Weights of the Elements 2009 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Everything Added to Food in the United States (EAFUS):View
CHEBI:View
CHEMBL:View
KEGG (GenomeNet):C05432
HMDB (The Human Metabolome Database):HMDB03000
FooDB:FDB015833
FDA Color Additive Status ListView
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
Wikipedia:View
RSC Learn Chemistry:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
 antioxidants
FRbalsam
FRoriental
 
Occurrence (nature, food, other):note
 apricot fruit
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 blood plasma
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 buckthorn sea buckthorn fruit
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 carrot root
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 date palm fruit
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 eggplant fruit
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 grape fruit
Search Trop Picture
 guava
Search Trop Picture
 melon bitter melon
Search Trop Picture
 melon bitter melon fruit
Search Trop Picture
 melon bitter melon pericarp
Search Trop Picture
 melon bitter melon seed
Search Trop Picture
 orange pericarp
Search Trop Picture
 papaya fruit
Search Trop Picture
 papaya pericarp
Search Trop Picture
 passion fruit
Search Trop Picture
 peach fruit
Search Trop Picture
 persimmon
Search Trop Picture
 rape
Search Trop Picture
 saffron stigma
Search Trop Picture
 tea leaf
Search Trop Picture
 tomato
Search Trop Picture
 tomato fruit
Search Trop Picture
 watermelon fruit
Search Trop Picture
 
Synonyms:
 c.i. 75125
psi,psi-carotene
 ci 75125
 lyco vit
(all-trans)-lycopene
all-trans-lycopene
trans-lycopene
 lycopene 10 CWD
 lycopene from blakeslea trispora
 lycopene from escherichia coli expressing lycopene biosynthetic enzymes
 lycopene powder extract 5%
 lycotene 10% FT
 lycotene 10% WSC
 lycotene 20% OS
 lycotene 20% TG
 lycotene P.E.
 lycovit
 natural yellow 27 c.i. 75125
(6E,8E,10E,12E, 14E,16E, 18E,20E,22E, 24E,26E)- 2,6,10,14,19,23, 27,31-octamethyl dotriaconta-2,6,8,10,12,14,16,18,20,22,24,26,30-tridecaene
(6E,8E,10E,12E,14E,16E,18E,20E,22E,24E,26E)-2,6,10,14,19,23,27,31-octamethyldotriaconta-2,6,8,10,12,14,16,18,20,22,24,26,30-tridecaene
 redivivo lycopene
 tomato color (lycopene base no. 35100 51; liquid)
 tomato lycopene
 

Articles:

PubMed:Lycopene fortification on the quality characteristics of beverage formulations developed from pink flesh guava (Psidium guajava L.).
J-Stage:Photostability of Lycopene Dispersed in an Aqueous Solution
PubMed:Formation of norisoprenoid flavor compounds in carrot (Daucus carota L.) roots: characterization of a cyclic-specific carotenoid cleavage dioxygenase 1 gene.
PubMed:Carotenoid content impacts flavor acceptability in tomato (Solanum lycopersicum).
PubMed:Substrate promiscuity of RdCCD1, a carotenoid cleavage oxygenase from Rosa damascena.
PubMed:The carotenoid cleavage dioxygenase 1 enzyme has broad substrate specificity, cleaving multiple carotenoids at two different bond positions.
PubMed:Qualitative and nutritional differences in processing tomatoes grown under commercial organic and conventional production systems.
PubMed:Enrichment of tomato flavor by diversion of the early plastidial terpenoid pathway.
PubMed:Effect of a tomato-based drink on markers of inflammation, immunomodulation, and oxidative stress.
PubMed:Stability of lycopene during food processing and storage.
PubMed:Effects of phosphorus fertilizer supplementation on processing quality and functional food ingredients in tomato.
PubMed:The tomato carotenoid cleavage dioxygenase 1 genes contribute to the formation of the flavor volatiles beta-ionone, pseudoionone, and geranylacetone.
PubMed:Applicability of CoA/acetyl-CoA manipulation system to enhance isoamyl acetate production in Escherichia coli.
PubMed:Commercial scale pulsed electric field processing of tomato juice.
PubMed:Enhanced levels of the aroma and flavor compound S-linalool by metabolic engineering of the terpenoid pathway in tomato fruits.
PubMed:Formation of volatile compounds during heating of spice paprika (Capsicum annuum) powder.
PubMed:Induction of AGAMOUS gene expression plays a key role in ripening of tomato sepals in vitro.
 
Notes:
Used as food colouring Lycopene (from the New Latin word lycopersicum for the tomato species name) is a bright red carotene and carotenoid pigment and phytochemical found in tomatoes and other red fruits and vegetables, such as red carrots, watermelons and papayas (but not strawberries or cherries). Although lycopene is chemically a carotene, it has no vitamin A activity. (Wikipedia) Constit. of tomatoes and many other fruits. Nutriceutical with antioxidant props. Lycopene (from the New Latin word lycopersicum for the tomato species name) is a bright red carotene and carotenoid pigment and phytochemical found in tomatoes and other red fruits and vegetables, such as red carrots, watermelons and papayas (but not strawberries or cherries). Although lycopene is chemically a carotene, it has no vitamin A activity. (Wikipedia)
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