alpha-hydroxymyristic acid
tetradecanoic acid, 2-hydroxy- (8CI)(9CI)

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Name: 2-hydroxytetradecanoic acid CAS Number: 2507-55-3 3D/inchi ECHA EINECS - REACH Pre-Reg: 219-714-0 FDA UNII: Search Nikkaji Web: J111.043H Beilstein Number: 1725369 MDL: MFCD00014342 XlogP3-AA: 5.30 (est) Molecular Weight: 244.37476000 Formula: C14 H28 O3 BioActivity Summary: listing NMR Predictor: Predict (works with chrome, Edge or firefox) Category:natural substances and extractives   US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information: Google Scholar: Search Google Books: Search Google Scholar: with word "volatile" Search Google Scholar: with word "flavor" Search Google Scholar: with word "odor" Search Google Patents: Search US Patents: Search EU Patents: Search Pubchem Patents: Search PubMed: Search NCBI: Search   Physical Properties: Assay: 95.00 to 100.00 Food Chemicals Codex Listed: No Melting Point: 51.00 °C. @ 760.00 mm Hg Boiling Point: 377.50 °C. @ 760.00 mm Hg (est) Flash Point: 385.00 °F. TCC ( 196.30 °C. ) (est) logP (o/w): 5.150 (est) Soluble in:   water, 17.82 mg/L @ 25 °C (est)   Organoleptic Properties: Odor and/or flavor descriptions from others (if found).   Cosmetic Information: None found   Suppliers: Santa Cruz Biotechnology For experimental / research use only. 2-Hydroxymyristic Acid >97% Sigma-Aldrich: Sigma For experimental / research use only. 2-Hydroxymyristic Acid ≥98% (capillary GC) sds   Safety Information: Preferred SDS: View   Hazards identification   Classification of the substance or mixture GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) None found. GHS Label elements, including precautionary statements   Pictogram   Hazard statement(s) None found. Precautionary statement(s) None found. Oral/Parenteral Toxicity: Not determined Dermal Toxicity: Not determined Inhalation Toxicity: Not determined   Safety in Use Information: Category: natural substances and extractives Recommendation for alpha-hydroxymyristic acid usage levels up to:   not for fragrance use.   Recommendation for alpha-hydroxymyristic acid flavor usage levels up to:   not for flavor use.   Safety References: EPI System: View AIDS Citations:Search Cancer Citations:Search Toxicology Citations:Search EPA ACToR:Toxicology Data EPA Substance Registry Services (SRS):Registry Laboratory Chemical Safety Summary :1563 National Institute of Allergy and Infectious Diseases:Data WGK Germany:3 2-hydroxytetradecanoic acid Chemidplus:0002507553   References:   2-hydroxytetradecanoic acid NIST Chemistry WebBook: Search Inchi Pubchem (cid): 1563 Pubchem (sid): 134983840 Pherobase: View   Other Information: (IUPAC): Atomic Weights of the Elements 2011 (pdf) Videos: The Periodic Table of Videos tgsc: Atomic Weights use for this web site (IUPAC): Periodic Table of the Elements CHEBI: View CHEMBL: View HMDB (The Human Metabolome Database): HMDB02261 FooDB: FDB022931 VCF-Online: VCF Volatile Compounds in Food ChemSpider: View   Potential Blenders and core components note None Found   Potential Uses: None Found   Occurrence (nature, food, other):note   angelica seed oil Search Trop Picture   Synonyms: 2- hydroxytetradecanoic acid alpha- hydroxytetradecanoic acid   tetradecanoic acid, 2-hydroxy   tetradecanoic acid, 2-hydroxy- (8CI)(9CI)   Articles:   None found yet. Try the PubMed Search.

Notes: 2-Hydroxymyristic acid is an analog of myristic acid that becomes metabolically activated in cells to form 2-hydroxymyristoyl-CoA, a potent inhibitor of myristoyl-CoA:protein N-myristoyltransferase, the enzyme that catalyzes protein N-myristoylation. Treatment of T cells with 2-hydroxymyristic acid inhibits the myristoylation and alters the stability of p56lck. (PMID 8103677) [HMDB]

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