EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

dulcin
urea, N-(4-ethoxyphenyl)-

Supplier Sponsors

Name:(4-ethoxyphenyl)urea
CAS Number: 150-69-6Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:205-767-7
FDA UNII: 8U78KF577Z
Nikkaji Web:J5.857B
Beilstein Number:2096445
MDL:MFCD00025431
XlogP3:1.00 (est)
Molecular Weight:180.20704000
Formula:C9 H12 N2 O2
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:information only not used for fragrances or flavors
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
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Google Patents:Search
US Patents:Search
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PubMed:Search
NCBI:Search
FDA Mainterm (SATF):150-69-6 ; DULCIN--PROHIBITED
FDA Regulation:
FDA PART 189 -- SUBSTANCES PROHIBITED FROM USE IN HUMAN FOOD
Subpart C--Substances Generally Prohibited From Direct Addition or Use as Human Food
Sec. 189.145 Dulcin.
 
Physical Properties:
Appearance:white crystalline powder (est)
Assay: 97.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 173.00 to 174.00 °C. @ 760.00 mm Hg
Boiling Point: 299.00 to 300.00 °C. @ 760.00 mm Hg (est)
Vapor Pressure:0.001000 mmHg @ 25.00 °C. (est)
Flash Point: 274.00 °F. TCC ( 134.60 °C. ) (est)
logP (o/w): 1.005 (est)
Soluble in:
 alcohol
 water, 1210 mg/L @ 21C (exp)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BOC Sciences
For experimental / research use only.
Urea,N-(4-ethoxyphenyl)-
Santa Cruz Biotechnology
For experimental / research use only.
Glycosine ≥95%
TCI AMERICA
For experimental / research use only.
(4-Ethoxyphenyl)urea >98.0%(HPLC)(N)
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50 3200 mg/kg
Arzneimittel-Forschung. Drug Research. Vol. 8, Pg. 150, 1958.

oral-rabbit LD50 4000 mg/kg
Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 52, Pg. 215, 1956.

oral-mouse LD50 700 mg/kg
FAO Nutrition Meetings Report Series. Vol. 44A, Pg. 100, 1967.

oral-child LDLo 400 mg/kg
GASTROINTESTINAL: NAUSEA OR VOMITING BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS"
Medizinische Klinik. Vol. 43, Pg. 105, 1948.

oral-dog LDLo 1000 mg/kg
"Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1345, 1935.

intraperitoneal-mouse LDLo 135 mg/kg
BEHAVIORAL: GENERAL ANESTHETIC BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Journal of Pharmacology and Experimental Therapeutics. Vol. 54, Pg. 188, 1935.

oral-woman LDLo 600 mg/kg
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS"
Medizinische Klinik. Vol. 43, Pg. 105, 1948.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
information only not used for fragrances or flavors
Recommendation for dulcin usage levels up to:
 not for fragrance use.
 
Recommendation for dulcin flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
Carcinogenic Potency Database:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :9013
National Institute of Allergy and Infectious Diseases:Data
(4-ethoxyphenyl)urea
Chemidplus:0000150696
EPA/NOAA CAMEO:hazardous materials
RTECS:YT2275000 for cas# 150-69-6
 
References:
 (4-ethoxyphenyl)urea
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):9013
Pubchem (sid):134973232
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):View
CHEBI:View
CHEMBL:View
KEGG (GenomeNet):C19415
HMDB (The Human Metabolome Database):HMDB32565
FooDB:FDB020407
Export Tariff Code:2924.21.4500
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 amino-N-(4-ethoxyphenyl)amide
4-ethoxy-phenylurea
4-ethoxyphenyl urea
(4-ethoxyphenyl)urea
1-(4-ethoxyphenyl)urea
N-(4-ethoxyphenyl)urea
4-ethoxyphenylurea
p-ethoxyphenylurea
 phenetolcarbamide
p-phenetolecarbamide
para-phenetolecarbamide
 sucrol
 suesstoff
 urea, (4-ethoxyphenyl)-
 urea, (p-ethoxyphenyl)-
 urea, N-(4-ethoxyphenyl)-
 valzin
 
 
Notes:
Sweetening agent ca. 250 times sweeter than sucrose. Prohibited from human food use in U.S.A. and other countries Constit. of Pithecellobium dulce (manila tamarind)
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