EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

camphane
1,7,7-trimethylbicyclo[2.2.1]heptane

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Name:4,7,7-trimethylbicyclo[2.2.1]heptane
CAS Number: 464-15-3Picture of molecule3D/inchi
FDA UNII: Search
Nikkaji Web:J11.345J
XlogP3-AA:4.00 (est)
Molecular Weight:138.25346000
Formula:C10 H18
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:natural substances and extractives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 157.00 to 159.00 °C. @ 760.00 mm Hg
Boiling Point: 160.00 to 162.00 °C. @ 760.00 mm Hg
Vapor Pressure:4.931000 mmHg @ 25.00 °C. (est)
Flash Point: 90.00 °F. TCC ( 32.40 °C. ) (est)
logP (o/w): 4.431 (est)
Soluble in:
 alcohol
 water, 4.409 mg/L @ 25 °C (est)
Insoluble in:
 water
 
Organoleptic Properties:
Odor Description:mild borneol
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BOC Sciences
For experimental / research use only.
bornane 95%
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
natural substances and extractives
Recommendation for camphane usage levels up to:
 not for fragrance use.
 
Recommendation for camphane flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :92108
National Institute of Allergy and Infectious Diseases:Data
4,7,7-trimethylbicyclo[2.2.1]heptane
Chemidplus:0000464153
 
References:
 4,7,7-trimethylbicyclo[2.2.1]heptane
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):92108
Pubchem (sid):135048054
Pherobase:View
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
CHEMBL:View
HMDB (The Human Metabolome Database):Search
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 elaeoselinum asclepium var. meoides
Search Trop Picture
 
Synonyms:
 bornane
 bornylane
1,7,7-trimethyl bicyclo(2.2.1)heptane
1,7,7-trimethylbicyclo[2.2.1]heptane
4,7,7-trimethylbicyclo[2.2.1]heptane
 

Articles:

PubMed:Antibacterial Adhesion of Borneol-Based Polymer via Surface Chiral Stereochemistry.
PubMed:Design of novel camphane-based derivatives with antimycobacterial activity.
PubMed:Antimycobacterial activity of chiral aminoalcohols with camphane scaffold.
PubMed:Synthesis and antimycobacterial activity of novel camphane-based agents.
PubMed:Novel camphane-based anti-tuberculosis agents with nanomolar activity.
PubMed:Oxygen activation by P450(cin): Protein and substrate mutagenesis.
PubMed:GC-MS analysis of the essential oils of ripe fruits, roots and flowering aerial parts of Elaeoselinum asclepium subsp. meoides growing in Sicily.
PubMed:Exploring a pocket for polycycloaliphatic groups in the CXCR3 receptor with the aid of a modular synthetic strategy.
PubMed:Composition, enantiomeric distribution, and antibacterial activity of the essential oil of Achillea ligustica All. from Corsica.
PubMed:Calocedimers A, B, C, and D from the bark of Calocedrus macrolepis var. formosana.
PubMed:Cytochrome P450cam-monoterpene interactions.
PubMed:Substrates modulate the rate-determining step for CO binding in cytochrome P450cam (CYP101). A high-pressure stopped-flow study.
PubMed:Toxaphenes and chlorinated naphthalenes in adipose tissue of children.
PubMed:Changes in secondary structure and salt links of cytochrome P-450cam induced by photoreduction: a Fourier transform infrared spectroscopic study.
PubMed:Monoterpene synthases from common sage (Salvia officinalis). cDNA isolation, characterization, and functional expression of (+)-sabinene synthase, 1,8-cineole synthase, and (+)-bornyl diphosphate synthase.
PubMed:Step-scan time-resolved FTIR spectroscopy of cytochrome P-450cam carbon monoxide complex: a salt link involved in the ligand-rebinding process.
PubMed:Mobility of norbornane-type substrates and water accessibility in cytochrome P-450cam.
PubMed:Substrate mobility in thiocamphor-bound cytochrome P450cam: an explanation of the conflict between the observed product profile and the X-ray structure.
PubMed:Crystal structures of cytochrome P-450CAM complexed with camphane, thiocamphor, and adamantane: factors controlling P-450 substrate hydroxylation.
PubMed:Biosynthesis of monoterpenes: stereochemistry of the coupled isomerization and cyclization of geranyl pyrophosphate to camphane and isocamphane monoterpenes.
PubMed:The roles of active site hydrogen bonding in cytochrome P-450cam as revealed by site-directed mutagenesis.
PubMed:Metabolism of camphanediols.
PubMed:The influence of some new nor-camphane derivatives on the coronary flow.
PubMed:Metabolism of camphors and related compounds.
PubMed:Camphane derivatives. VII. Syntheses and structure of 3-methyl-3a-beta, 7a-beta-beta-bornano[3,2-d]oxazolidin-2-one and its derivatives.
PubMed:[SYNTHESES OF ANALGESICS. XXXV. CAMPHANE DERIVATIVES. (6). SYNTHESES OF CAMPHORIMIDE AND ITS DERIVATIVES].
PubMed:[SYNTHESES OF ANALGESICS. XXXIV. CAMPHANE DERIVATIVES. (5). SYNTHESES OF 9- AND 10-HYDROXYCAMPHOR DERIVATIVES].
PubMed:[SYNTHESES OF ANALGESICS. 33. CAMPHANE DERIVATIVES. (4). SYNTHESES OF N-(3-CAMPHORYL)-AND N-(2-HYDROXY-3-BORNANYL-AMINO ACID DERIVATES].
PubMed:[SYNTHESES OF ANALGESICS. XXXII. CAMPHANE DERIVATIVES. (3). SYNTHESES OF 1-ALKYL-3-(3-CAMPHORYL)UREAS AND THIOUREAS].
PubMed:[Modification of work and learning ability in rats and pigeons by 2-ethylamino-3-phenylnor-camphane].
 
Notes:
None found
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