EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

gambir
uncaria gambir roxb.

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CAS Number: 8001-48-7
Other(deleted CASRN):9000-26-4
ECHA EC Number:232-285-4
FDA UNII: 3NJQ5D8S6N
Formula:unspecified
Category:flavor and texture modifiers
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
FDA Mainterm (SATF):8001-48-7 ; GAMBIR (UNCARIA GAMBIR ROXB.)
FDA Regulation:
FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION
Subpart F--Flavoring Agents and Related Substances
Sec. 172.510 Natural flavoring substances and natural substances used in conjunction with flavors.
 
Physical Properties:
Food Chemicals Codex Listed: No
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BOC Sciences
For experimental / research use only.
Catechu 95%
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
flavor and texture modifiers
Recommendation for gambir usage levels up to:
 not for fragrance use.
 
 
Safety References:
EPA Substance Registry Services (TSCA):8001-48-7
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
National Institute of Allergy and Infectious Diseases:Data
Chemidplus:0008001487
 
References:
Canada Domestic Sub. List:8001-48-7
Pubchem (sid):135281104
 
Other Information:
FDA Substances Added to Food (formerly EAFUS):View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 uncaria gambir
Search Trop Picture
 
Synonyms:
 catechu
 gambir catechu
 pale catechu
 uncaria gambir roxb.
 

Articles:

PubMed:Gambir, "Gambir Sarawak" and toad venom.
PubMed:A novel α-glucosidase inhibitory constituent from Uncaria gambir.
PubMed:Cytotoxic data of 14-deoxy-11, 12-didehydroandrographolide (14-DDA), double transfection and DDIT3 silencing data in T-47D breast carcinoma cells.
PubMed:14-Deoxy-11,12-didehydroandrographolide induces DDIT3-dependent endoplasmic reticulum stress-mediated autophagy in T-47D breast carcinoma cells.
PubMed:Development of resazurin-based assay in 384-well format for high throughput whole cell screening of Trypanosoma brucei rhodesiense strain STIB 900 for the identification of potential anti-trypanosomal agents.
PubMed:Molecular modelling, synthesis and biological evaluation of peptide inhibitors as anti-angiogenic agent targeting neuropilin-1 for anticancer application.
PubMed:H274Y's Effect on Oseltamivir Resistance: What Happens Before the Drug Enters the Binding Site.
PubMed:Potent PPARγ Ligands from Swietenia macrophylla Are Capable of Stimulating Glucose Uptake in Muscle Cells.
PubMed:A simple and simultaneous identification method for aloe, catechu and gambir by high performance liquid chromatography.
PubMed:Targeting Heat Shock Proteins 60 and 70 of Toxoplasma gondii as a Potential Drug Target: In Silico Approach.
PubMed:Analgesic and anti-Inflammatory effect of UP3005, a botanical composition Containing two standardized extracts of Uncaria gambir and Morus alba.
PubMed:Binding specificity of polypeptide substrates in NS2B/NS3pro serine protease of dengue virus type 2: A molecular dynamics Study.
PubMed:UP3005, a Botanical Composition Containing Two Standardized Extracts of Uncaria gambir and Morus alba, Improves Pain Sensitivity and Cartilage Degradations in Monosodium Iodoacetate-Induced Rat OA Disease Model.
PubMed:Potential inhibitors for isocitrate lyase of Mycobacterium tuberculosis and non-M. tuberculosis: a summary.
PubMed:A virtual screening approach for identifying plants with anti H5N1 neuraminidase activity.
PubMed:The capacity for long-chain polyunsaturated fatty acid synthesis in a carnivorous vertebrate: Functional characterisation and nutritional regulation of a Fads2 fatty acyl desaturase with Δ4 activity and an Elovl5 elongase in striped snakehead (Channa striata).
PubMed:Cytochrome P450 induction properties of food and herbal-derived compounds using a novel multiplex RT-qPCR in vitro assay, a drug-food interaction prediction tool.
PubMed:In Silico Investigation of a HIV-1 Vpr Inhibitor Binding Site: Potential for Virtual Screening and anti-HIV Drug Design.
PubMed:The mTOR signalling pathway in cancer and the potential mTOR inhibitory activities of natural phytochemicals.
PubMed:Synthesis of novel derivatives of 4-methylbenzimidazole and evaluation of their biological activities.
PubMed:9-Benzyl-6-benzyl-sulfanyl-9H-purin-2-amine.
PubMed:Diagnosis of periprosthetic joint infection.
PubMed:Diagnosis of periprosthetic joint infection.
PubMed:Antioxidant and cytoprotective activities of Piper betle, Areca catechu, Uncaria gambir and betel quid with and without calcium hydroxide.
PubMed:The effect of mitragynine on cAMP formation and mRNA expression of mu-opioid receptors mediated by chronic morphine treatment in SK-N-SH neuroblastoma cell.
PubMed:Cardioankle vascular index evaluations revealed that cotreatment of ARB Antihypertension medication with traditional Chinese medicine improved arterial functionality.
PubMed:Cytotoxic and Apoptotic Effects of Ethyl Acetate Extract of Elephantopus mollis Kunth. in Human Liver Carcinoma HepG2 Cells Through Caspase-3 Activation.
PubMed:Mitragynine attenuates withdrawal syndrome in morphine-withdrawn zebrafish.
PubMed:Identification of genes involved in the regulation of 14-deoxy-11,12-didehydroandrographolide-induced toxicity in T-47D mammary cells.
PubMed:Genetic variation of glucose transporter-1 (GLUT1) and albuminuria in 10,278 European Americans and African Americans: a case-control study in the Atherosclerosis Risk in Communities (ARIC) study.
PubMed:Antinociceptive and antiinflammatory activities of the aqueous extract of Trigonopleura malayana resin in experimental animal models.
PubMed:[The history of tooth dyeing].
PubMed:[Evaluation of gambir quality based on quantitative analysis of polyphenolic constituents].
PubMed:Revised structures of gambiriins A1, A2, B1, and B2, chalcane-flavan dimers from gambir (Uncaria gambir extract).
PubMed:Antimicrobial susceptibility of community-acquired uropathogens in general practice.
PubMed:[The health benefits of gambir].
PubMed:[Traditional nostrum].
PubMed:[A gambir recipe brought by Ganjin, a Chinese buddhist dignitary].
PubMed:[China-home of the tea drinking custom].
PubMed:[The roots of Cha and Gambir].
PubMed:[Pharmacological action of Gambir.].
PubMed:[Recognize uncalia ganbir].
PubMed:Effective medicinal plants against enterohaemorrhagic Escherichia coli O157:H7.
PubMed:Effects of herbal drugs prescribed in wood creosote pills on the dissolution profile of guaiacol.
PubMed:[Gambir revisted].
PubMed:Direct scavenging of nitric oxide by traditional crude drugs.
PubMed:Lupus miliaris disseminatus faciei.
PubMed:Widespread tannin intake via stimulants and masticatories, especially guarana, kola nut, betel vine, and accessories.
PubMed:Liposarcoma of the cheek.
PubMed:The effects of betel-nut chewing on the buccal mucosa of 296 Indians and Malays in West Malaysia. A clinical study.
PubMed:Gambirdine and isogambirdine, the alkaloids from Uncaria gambir (Hunt) Roxb.
PubMed:Studies on flavonoid metabolism. Biosynthesis of (+)-[14C]catechin by the plant Uncaria gambir Roxb.
 
Notes:
tsca definition 2008: extractives and their physically modified derivatives. it is a product which may contain resin acids and their esters, terpenes, and oxidation or polymerization products of these terpenes. (uncaria gambier or ourouparia gambier, rubiaceae.)
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