| Name: | swertia chirata buch. ham. |
| FDA internal no.: | 977052-80-4 |
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| FDA UNII: | Search |
| CoE Number: | 440 |
Category:spices, other natural seasonings and flavorings
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Food Chemicals Codex Listed: | No |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | spices, other natural seasonings and flavorings |
| Recommendation for chirata usage levels up to: | | | not for fragrance use.
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| Recommendation for chirata flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
| | swertia chirata buch. ham. |
| Pubchem (sid): | 135332371 |
Other Information:
| FDA Substances Added to Food (formerly EAFUS): | View |
| FDA Listing of Food Additive Status: | View |
| Wikipedia: | View |
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | swertia chirata buch. ham. | | | swertia chirata herb |
Articles:
| PubMed:CYP450 mediated inhibition potential of Swertia chirata: An herb from Indian traditional medicine. |
| PubMed:Amarogentin regulates self renewal pathways to restrict liver carcinogenesis in experimental mouse model. |
| PubMed:Antibacterial, Antifungal and antioxidant activities of some medicinal plants. |
| PubMed:Expression of pro-inflammatory interleukin-8 is reduced by ayurvedic decoctions. |
| PubMed:Insights from the predicted interactions of plant derived compounds to the gluco-corticoid receptor as an alternative to dexa-methasone. |
| PubMed:Prevention of liver carcinogenesis by amarogentin through modulation of G1/S cell cycle check point and induction of apoptosis. |
| PubMed:Insights into mechanisms underlying the gut and airways modulatory effects of Swertia chirata. |
| PubMed:Highlighting the anti-carcinogenic potential of an ayurvedic medicinal plant, Swertia Chirata. |
| PubMed:Report: analgesic activities of ethanol extract of leaf, stem and their different fractions of Swertia chirata. |
| PubMed:In vitro antimicrobial activities of different fractions of Swertia chirata ethanolic extract. |
| PubMed:Protocol for in vitro regeneration and marker glycoside assessment in Swertia chirata Buch-Ham. |
| PubMed:Assessment of systemic interaction between Swertia chirata extract and its Bioactive constituents in rabbits. |
| PubMed:Antiviral activity of the Indian medicinal plant extract Swertia chirata against herpes simplex viruses: a study by in-vitro and molecular approach. |
| PubMed:Simultaneous estimation of mangiferin and four secoiridoid glycosides in rat plasma using liquid chromatography tandem mass spectrometry and its application to pharmacokinetic study of herbal preparation. |
| PubMed:Liquid chromatography/tandem mass spectrometric study and analysis of xanthone and secoiridoid glycoside composition of Swertia chirata, a potent antidiabetic. |
| PubMed:Anthelmintic activity of Swertia chirata against gastrointestinal nematodes of sheep. |
| PubMed:Amarogentin can reduce hyperproliferation by downregulation of Cox-II and upregulation of apoptosis in mouse skin carcinogenesis model. |
| PubMed:Evaluation of the anticarcinogenic activity of Swertia chirata Buch.Ham, an Indian medicinal plant, on DMBA-induced mouse skin carcinogenesis model. |
| PubMed:Phenylalanine-independent biosynthesis of 1,3,5,8-tetrahydroxyxanthone. A retrobiosynthetic NMR study with root cultures of Swertia chirata. |
| PubMed:Regulation of hazardous exposure by protective exposure: modulation of phase II detoxification and lipid peroxidation by Camellia sinensis and Swertia chirata. |
| PubMed:In vitro antimalarial activity of extracts of three plants used in the traditional medicine of India. |
| PubMed:alpha-Glucosidase inhibitory activity of Mangifera indica bark. |
| PubMed:Screening of various Swertia species extracts in primary monolayer cultures of rat hepatocytes against carbon tetrachloride- and paracetamol-induced toxicity. |
| PubMed:Tyrosinase inhibitory activity of Bangladeshi indigenous medicinal plants. |
| PubMed:Production of amarogentin in root cultures of Swertia chirata. |
| PubMed:Review on some plants of Indian traditional medicine with antioxidant activity. |
| PubMed:Superoxide-scavenging and prolyl endopeptidase inhibitory activities of Bangladeshi indigenous medicinal plants. |
| PubMed:Evaluation of the in-vivo activity and toxicity of amarogentin, an antileishmanial agent, in both liposomal and niosomal forms. |
| PubMed:Antihepatotoxic activity of Swertia chirata on paracetamol and galactosamine induced hepatotoxicity in rats. |
| PubMed:Antihepatotoxic activity of Swertia chirata on carbon tetrachloride induced hepatotoxicity in rats. |
| PubMed:Hepatoprotective effect of Swertia chirata on rat. |
| PubMed:Amarogentin, a naturally occurring secoiridoid glycoside and a newly recognized inhibitor of topoisomerase I from Leishmania donovani. |
| PubMed:Protective effect of Swertia chirata against indomethacin and other ulcerogenic agent-induced gastric ulcers. |
| PubMed:Chemical constituents of Gentianaceae XIX: CNS-depressant effects of swertiamarin. |
| PubMed:Chemical constituents of the gentianaceae V: tetraoxygenated xanthones of Swertia chirata Buch.-Ham. |
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