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hypericum perforatum flower/leaf/stem extract
extract of the flowers, leaves and stems of the st. john's wort, hypericum perforatum l., hypericaceae

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Name:hypericum perforatum l. flower/leaf/stem extract
CAS Number: 84082-80-4
ECHA EC Number:282-026-4
FDA UNII: Search
Category:cosmetic ingredient for skin conditioning
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Physical Properties:
Food Chemicals Codex Listed: No
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: skin conditioning
St. John’s Wort Herb Hypericum Perforatum Flower/Leaf/Stem Extract
St. John’s Wort in Safflower Oil – 3709
Phytoconcentrole® St. John's Wort
Life Essentials - Botanicals
Odor: characteristic
Use: Phytoconcentrole® St. John´s Wort contains the extract of Hypericum perforatum L. herb prepared in neutral oil. St. john´s wort used for our Phytoconcentrole® is mainly cultivated in Eastern Europe. The herb is dried, if necessary comminuted, extracted with a blend of water and ethanol and filtrated. The filtrate is concentrated by distillation and thereby the alcohol is completely removed. The concentrated extract is prepared in neutral oil and clear filtrated after an individual ripening time. 1 kg Phytoconcentrole® St. John´s Wort contains the lipophilic ingredients of approx. 100 g dried, resp. approx. 750 g fresh herb. Dried plant material - Phytoconcentrole® St. John´s Wort - ratio: 0.1 : 1. Fresh plant material - Phytoconcentrole® St. John´s Wort - ratio: 0.75: 1
Safety Information:
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Safety in Use Information:
cosmetic ingredient for skin conditioning
Recommendation for hypericum perforatum flower/leaf/stem extract usage levels up to:
 not for fragrance use.
Recommendation for hypericum perforatum flower/leaf/stem extract flavor usage levels up to:
 not for flavor use.
Safety References:
Daily Med:search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
National Institute of Allergy and Infectious Diseases:Data
hypericum perforatum l. flower/leaf/stem extract
 hypericum perforatum l. flower/leaf/stem extract
Pubchem (sid):135317821
Other Information:
Potential Blenders and core components note
None Found
Potential Uses:
None Found
Occurrence (nature, food, other):note
 st. john's wort flower
Search Trop Picture
 extract of the flowers, leaves and stems of the st. john's wort, hypericum perforatum l., hypericaceae
 millepertius flower/leaf/stem extract
phytoconcentrole st. john's wort (Symrise)
 st. john's wort flower/leaf/stem extract


PubMed:Effect of St. John's Wort (Hypericum perforatum) on obesity, lipid metabolism and uterine epithelial proliferation in ovariectomized rats.
PubMed:Computational identification of conserved microRNAs and their putative targets in the Hypericum perforatum L. flower transcriptome.
PubMed:Isolation of Cronobacter sakazakii from different herbal teas.
PubMed:A comparative study on the effects of Hypericum Perforatum and passion flower on the menopausal symptoms of women referring to Isfahan city health care centers.
PubMed:Pharmacological studies in an herbal drug combination of St. John's Wort (Hypericum perforatum) and passion flower (Passiflora incarnata): in vitro and in vivo evidence of synergy between Hypericum and Passiflora in antidepressant pharmacological models.
PubMed:Optimization of protein extraction from Hypericum perforatum tissues and immunoblotting detection of Hyp-1 at different stages of leaf development.
PubMed:Octaketide-producing type III polyketide synthase from Hypericum perforatum is expressed in dark glands accumulating hypericins.
PubMed:Molecular cloning and tissue-specific expression of two cDNAs encoding polyketide synthases from Hypericum perforatum.
PubMed:Cytotoxic activity of Hypericum perforatum L. on K562 erythroleukemic cells: differential effects between methanolic extract and hypericin.
PubMed:Mammalian neurohormones: potential significance in reproductive physiology of St. John's wort (Hypericum perforatum L.)?
PubMed:An in vitro and hydroponic growing system for hypericin, pseudohypericin, and hyperforin production of St. John's wort (Hypericum perforatum CV new stem).
PubMed:Determination of St. John's wort components in dietary supplements and functional foods by liquid chromatography.
PubMed:[Metabolic effects and drug interactions provoked by certain vegetables: grapefruit, St. John's wort and garlic].
PubMed:Supercritical fluid extraction and high-performance liquid chromatographic determination of phloroglucinols in St. John's Wort (Hypericum perforatum L.).
PubMed:Quantitative changes of dianthrones, hyperforin and flavonoids content in the flower ontogenesis of Hypericum perforatum.
PubMed:Simultaneous determination of the predominant hyperforins and hypericins in St. John's Wort (Hypericum perforatum L.) by liquid chromatography.
PubMed:Inhibition of benzodiazepine binding in vitro by amentoflavone, a constituent of various species of Hypericum.
PubMed:Levels of some microelements and essential heavy metals in herbal teas in Serbia.
PubMed:Hypericum perforatum hydroxyalkylpyrone synthase involved in sporopollenin biosynthesis - phylogeny, site-directed mutagenesis, and expression in nonanther tissues.
None found
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