angelica gigas root water
aqueous solution of the steam distillates obtained from the roots of angelica gigas, apiaceae
 
Notes:
None found
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Category: cosmetic ingredient for skin conditioning
 
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Physical Properties:
Food Chemicals Codex Listed: No
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Organoleptic Properties:
  
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: skin conditioning
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Suppliers:
 None found
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: cosmetic ingredient for skin conditioning
Recommendation for angelica gigas root water usage levels up to:
 not for fragrance use.
 
Recommendation for angelica gigas root water flavor usage levels up to:
 not for flavor use.
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Safety References:
None found
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References:
None found
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Other Information:
Wikipedia: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 angelica gigas root
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Synonyms:
 aqueous solution of the steam distillates obtained from the roots of angelica gigas, apiaceae
 chao xian dang gui root water
 oni-nodake root water
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Articles:
PubMed: Single oral dose pharmacokinetics of decursin, decursinol angelate, and decursinol in rats.
PubMed: Ultrafine Angelica gigas powder normalizes ovarian hormone levels and has antiosteoporosis properties in ovariectomized rats: particle size effect.
PubMed: Protective effects of a novel synthetic α-lipoic acid-decursinol hybrid compound in experimentally induced transient cerebral ischemia.
PubMed: Anti-cancer and other bioactivities of Korean Angelica gigas Nakai (AGN) and its major pyranocoumarin compounds.
PubMed: Quantitative determination of decursin, decursinol angelate, and decursinol in mouse plasma and tumor tissue using liquid-liquid extraction and HPLC.
PubMed: Overexpression of cinnamate 4-hydroxylase gene enhances biosynthesis of decursinol angelate in Angelica gigas hairy roots.
PubMed: Antiplasmodial and cytotoxic activity of coumarin derivatives from dried roots of Angelica gigas Nakai in vitro.
PubMed: Decursin inhibits growth of human bladder and colon cancer cells via apoptosis, G1-phase cell cycle arrest and extracellular signal-regulated kinase activation.
PubMed: Biotransformation of plant secondary metabolite decursin by Mycobacterium sp. PYR1001.
PubMed: Decursin and decursinol inhibit VEGF-induced angiogenesis by blocking the activation of extracellular signal-regulated kinase and c-Jun N-terminal kinase.
PubMed: In vitro inhibitory potential of decursin and decursinol angelate on the catalytic activity of cytochrome P-450 1A1/2, 2D15, and 3A12 isoforms in canine hepatic microsomes.
PubMed: Inhibitory effects of Angelicae Gigantis Radix on osteoclast formation.
PubMed: Neuroprotective coumarins from the root of Angelica gigas: structure-activity relationships.
PubMed: The simultaneous determination of coumarins in Angelica gigas root by high performance liquid chromatography-diode array detector coupled with electrospray ionization/mass spectrometry.
PubMed: Decursin suppresses human androgen-independent PC3 prostate cancer cell proliferation by promoting the degradation of beta-catenin.
PubMed: Oriental herbs as a source of novel anti-androgen and prostate cancer chemopreventive agents.
PubMed: Potent antiandrogen and androgen receptor activities of an Angelica gigas-containing herbal formulation: identification of decursin as a novel and active compound with implications for prevention and treatment of prostate cancer.
PubMed: A novel anticancer agent, decursin, induces G1 arrest and apoptosis in human prostate carcinoma cells.
PubMed: Quantification of ligustilides in the roots of Angelica sinensis and related umbelliferous medicinal plants by high-performance liquid chromatography and liquid chromatography-mass spectrometry.
PubMed: Decursinol angelate: a cytotoxic and protein kinase C activating agent from the root of Angelica gigas.
PubMed: Decursin: a cytotoxic agent and protein kinase C activator from the root of Angelica gigas.
PubMed: Coumarins from the root of Angelica gigas Nakai.
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