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symphytum officinale root tincture
comfrey root tincture

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CAS Number:	84696-05-9
ECHA EC Number:	283-625-3
FDA UNII:	Search

Category:information only not used for fragrances or flavors

US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:

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Physical Properties:

Food Chemicals Codex Listed:

No

Organoleptic Properties:

Odor and/or flavor descriptions from others (if found).

Cosmetic Information:

None found

Suppliers:

Bristol Botanicals

Comfrey root tincture Symphytum officinale 1:8 25%

Safety Information:


Hazards identification

Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements

Pictogram

Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in Use Information:

Category:
information only not used for fragrances or flavors
Recommendation for symphytum officinale root tincture usage levels up to:
	not for fragrance use.

Recommendation for symphytum officinale root tincture flavor usage levels up to:
	not for flavor use.

Safety References:

Daily Med:search

AIDS Citations:Search

Cancer Citations:Search

Toxicology Citations:Search

EPA ACToR:Toxicology Data

EPA Substance Registry Services (SRS):Registry

National Institute of Allergy and Infectious Diseases:Data

symphytum officinale root tincture

Chemidplus:0084696059

References:

	symphytum officinale root tincture
Pubchem (sid):	135307585

Other Information:

Wikipedia:

Potential Blenders and core components note

None Found

Potential Uses:

None Found

Occurrence (nature, food, other):note

comfrey root
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Synonyms:

	comfrey root tincture
quaker	comfrey root tincture
	symphytum officinalis root tincture

Articles:

PubMed:Herbal medicine for low-back pain.

PubMed:TLC densitometric method for screening of lycopsamine in comfrey root (Symphytum officinale L.) extracts using retrorsine as a reference compound.

PubMed:Semi-automated separation of the epimeric dehydropyrrolizidine alkaloids lycopsamine and intermedine: preparation of their N-oxides and NMR comparison with diastereoisomeric rinderine and echinatine.

PubMed:Comfrey root: from tradition to modern clinical trials.

PubMed:Distinct cell-specific expression of homospermidine synthase involved in pyrrolizidine alkaloid biosynthesis in three species of the boraginales.

PubMed:Effect of a blend of comfrey root extract (Symphytum officinale L.) and tannic acid creams in the treatment of osteoarthritis of the knee: randomized, placebo-controlled, double-blind, multiclinical trials.

PubMed:MicroRNAs and their predicted target messenger RNAs are deregulated by exposure to a carcinogenic dose of comfrey in rat liver.

PubMed:Absence of mutagenic effects of a particular Symphytum officinale L. liquid extract in the bacterial reverse mutation assay.

PubMed:Lead chelation to immobilised Symphytum officinale L. (comfrey) root tannins.

PubMed:Comparison of gene expression profiles altered by comfrey and riddelliine in rat liver.

PubMed:Assays of physical stability and antioxidant activity of a topical formulation added with different plant extracts.

PubMed:Efficacy and tolerance of a comfrey root extract (Extr. Rad. Symphyti) in the treatment of ankle distorsions: results of a multicenter, randomized, placebo-controlled, double-blind study.

PubMed:A rapid cleanup method for the isolation and concentration of pyrrolizidine alkaloids in comfrey root.

PubMed:The influence of phytohormones on growth, organ differentiation and fructan production in callus of Symphytum officinale L.

PubMed:Mutagenic effects of aqueous extracts of Symphytum officinale L. and of its alkaloidal fractions.

PubMed:[Development of root-layers of symphytum officinale L. and their storage and consumption of carbohydrates].

PubMed:[Annual developmental cycle of roots and shoots in Symphytum officinale L. in relation to storage and consumption of carbohydrates].

PubMed:Comfrey (Symphytum officinale L.) root; its anatomy and its detection in admixture with chicory in dandelion coffee.

Notes:

perennial herb symphytum officinale, in the family boraginaceae, used topically for wound healing. it contains allantoin, carotene, essential oils ( oils, volatile); glycosides; mucilage, resin, saponins; tannins; triterpenoids, vitamin b12, and zinc. comfrey also contains pyrrolizidine alkaloids and is hepatotoxic if ingested.

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