| PubMed:Scolicidal Effects of Black Cumin Seed (Nigella sativa) Essential Oil on Hydatid Cysts. |
| PubMed:Enhanced cytotoxicity and apoptosis by thymoquinone in combination with zoledronic acid in hormone- and drug-resistant prostate cancer cell lines. |
| PubMed:Thymoquinone Inhibits Murine Leukemia WEHI-3 Cells In Vivo and In Vitro. |
| PubMed:The thymoquinone-induced production of reactive oxygen species promotes dedifferentiation through the ERK pathway and inflammation through the p38 and PI3K pathways in rabbit articular chondrocytes. |
| PubMed:Anti-microbial effect of Nigella sativa seed extract against staphylococcal skin Infection. |
| PubMed:Protective effect of thymoquinone against high-fructose diet-induced metabolic syndrome in rats. |
| PubMed:Apoptotic Activities of Thymoquinone, an Active Ingredient of Black Seed (Nigella sativa), in Cervical Cancer Cell Lines. |
| PubMed:Thymoquinone inhibits proliferation and invasion of human nonsmall-cell lung cancer cells via ERK pathway. |
| PubMed:Potential protective effects of Nigella sativa and Allium sativum against fructose-induced metabolic syndrome in rats. |
| PubMed:Mitigating role of thymoquinone rich fractions from Nigella sativa oil and its constituents, thymoquinone and limonene on lipidemic-oxidative injury in rats. |
| PubMed:Dietary supplementation of chloroquine with nigella sativa seed and oil extracts in the treatment of malaria induced in mice with plasmodium berghei. |
| PubMed:Therapeutic Implications of Black Seed and Its Constituent Thymoquinone in the Prevention of Cancer through Inactivation and Activation of Molecular Pathways. |
| PubMed:Endothelium-independent vasorelaxant effects of hydroalcoholic extract from Nigella sativa seed in rat aorta: the roles of Ca2+ and K+ channels. |
| PubMed:Thymoquinone induces apoptosis in human colon cancer HCT116 cells through inactivation of STAT3 by blocking JAK2- and Src‑mediated phosphorylation of EGF receptor tyrosine kinase. |
| PubMed:Stable isotope dilution gas chromatography-mass spectrometry for quantification of thymoquinone in black cumin seed oil. |
| PubMed:Effects of Nigella sativa L. seed oil on abnormal semen quality in infertile men: a randomized, double-blind, placebo-controlled clinical trial. |
| PubMed:Natural products as topoisomerase II poisons: effects of thymoquinone on DNA cleavage mediated by human topoisomerase IIα. |
| PubMed:Induction of apolipoprotein A-I gene expression by black seed (Nigella sativa) extracts. |
| PubMed:Increased 5-HT Levels Following Repeated Administration of Nigella sativa L. (Black Seed) Oil Produce Antidepressant Effects in Rats. |
| PubMed:Bioactivity-guided identification to delineate the immunomodulatory effects of methanolic extract of Nigella sativa seed on human peripheral blood mononuclear cells. |
| PubMed:Cytotoxicity of Nigella sativa seed oil and extract against human lung cancer cell line. |
| PubMed:Effect of dietary supplementation of black seed (N. Sativa L.) on lipid profile of patients suffering from diabetes. |
| PubMed:Metabolomics driven analysis of six Nigella species seeds via UPLC-qTOF-MS and GC-MS coupled to chemometrics. |
| PubMed:Topical Nigella Sativa for nasal symptoms in elderly. |
| PubMed:Authentication of Nigella sativa seed oil in binary and ternary mixtures with corn oil and soybean oil using FTIR spectroscopy coupled with partial least square. |
| PubMed:Thymoquinone causes multiple effects, including cell death, on dividing plant cells. |
| PubMed:The effect of thymoquinone, an active component of Nigella sativa, on isoproterenol induced myocardial injury. |
| PubMed:The effect of black seed (Nigella sativa) extract on FOXO3 expression in HepG2 cells. |
| PubMed:Molecular targeting of Akt by thymoquinone promotes G(1) arrest through translation inhibition of cyclin D1 and induces apoptosis in breast cancer cells. |
| PubMed:Thymoquinone inhibits autophagy and induces cathepsin-mediated, caspase-independent cell death in glioblastoma cells. |
| PubMed:Thymoquinone induces mitochondria-mediated apoptosis in acute lymphoblastic leukaemia in vitro. |
| PubMed:The investment in scent: time-resolved metabolic processes in developing volatile-producing Nigella sativa L. seeds. |
| PubMed:Thymoquinone: fifty years of success in the battle against cancer models. |
| PubMed:The clinical outcome of adjuvant therapy with black seed oil on intractable paediatric seizures: a pilot study. |
| PubMed:Lepidium sativum but not Nigella sativa affects carbamazepine disposition in an animal model. |
| PubMed:Comparative effects of using black seed (Nigella sativa), cumin seed (Cuminum cyminum), probiotic or prebiotic on growth performance, blood haematology and serum biochemistry of broiler chicks. |
| PubMed:Cellular responses with thymoquinone treatment in human breast cancer cell line MCF-7. |
| PubMed:Evaluation of topical black seed oil in the treatment of allergic rhinitis. |
| PubMed:Effect of Nigella sativa and Allium sativum coadminstered with simvastatin in dyslipidemia patients: a prospective, randomized, double-blind trial. |
| PubMed:Thymoquinone-loaded nanostructured lipid carriers: preparation, gastroprotection, in vitro toxicity, and pharmacokinetic properties after extravascular administration. |
| PubMed:Thymoquinone-induced reactive oxygen species causes apoptosis of chondrocytes via PI3K/Akt and p38kinase pathway. |
| PubMed:Elucidation of mechanisms of actions of thymoquinone-enriched methanolic and volatile oil extracts from Nigella sativa against cardiovascular risk parameters in experimental hyperlipidemia. |
| PubMed:The effect of Nigella sativa Linn. seed on memory, attention and cognition in healthy human volunteers. |
| PubMed:Thymoquinone attenuates tumor growth in ApcMin mice by interference with Wnt-signaling. |
| PubMed:Nigella sativa seed extract: 1. Enhancement of sheep macrophage immune functions in vitro. |
| PubMed:Effects of selected bioactive natural products on the vascular endothelium. |
| PubMed:Effects of black cumin seed (Nigella sativa L.) on performance and immune system in newly evolved crossbred laying hens. |
| PubMed:Hepatoprotective and immunological functions of Nigella sativa seed oil against hypervitaminosis A in adult male rats. |
| PubMed:Thymoquinone suppresses metastasis of melanoma cells by inhibition of NLRP3 inflammasome. |
| PubMed:Effects of black seed oil on resolution of hepato-renal toxicity induced bybromobenzene in rats. |
| PubMed:Thymoquinone protects cultured rat primary neurons against amyloid β-induced neurotoxicity. |
| PubMed:Methanolic extract of Nigella sativa seed inhibits SiHa human cervical cancer cell proliferation through apoptosis. |
| PubMed:Blood pressure lowering effect of Nigella sativa L. seed oil in healthy volunteers: a randomized, double-blind, placebo-controlled clinical trial. |
| PubMed:Effects of Lepidium sativum, Nigella sativa and Trigonella foenum-graceum on phenytoin pharmacokinetics in beagle dogs. |
| PubMed:Anti-inflammatory effect of seeds and callus of Nigella sativa L. extracts on mix glial cells with regard to their thymoquinone content. |
| PubMed:Hormetic/cytotoxic effects of Nigella sativa seed alcoholic and aqueous extracts on MCF-7 breast cancer cells alone or in combination with doxorubicin. |
| PubMed:High-performance liquid chromatography quantification of principal antioxidants in black seed (Nigella sativa L.) phytopharmaceuticals. |
| PubMed:NADPH quinone oxidoreductase 1 mediates breast cancer cell resistance to thymoquinone-induced apoptosis. |
| PubMed:Distribution of primary and specialized metabolites in Nigella sativa seeds, a spice with vast traditional and historical uses. |
| PubMed:Cardiovascular benefits of black cumin (Nigella sativa). |
| PubMed:Use of complementary and alternative medicine by patients with cancer in Saudi Arabia. |
| PubMed:Nigella sativa (black cumin) seed extract alleviates symptoms of allergic diarrhea in mice, involving opioid receptors. |
| PubMed:Can methanolic extract of Nigella sativa seed affect glyco-regulatory enzymes in experimental hepatocellular carcinoma? |
| PubMed:Biosynthesis of controllable size and shape gold nanoparticles by black seed (Nigella sativa) extract. |
| PubMed:The enhancing effects of alcoholic extract of Nigella sativa seed on fertility potential, plasma gonadotropins and testosterone in male rats. |
| PubMed:Cadmium-induced hepatotoxicity and its abrogation by thymoquinone. |
| PubMed:Thymoquinone prevents and ameliorates dextran sulfate sodium-induced colitis in mice. |
| PubMed:Characterization of secondary volatile profiles in Nigella sativa seeds from two different origins using accelerated solvent extraction and gas chromatography-mass spectrometry. |
| PubMed:Thymoquinone inhibits growth and augments 5-fluorouracil-induced apoptosis in gastric cancer cells both in vitro and in vivo. |
| PubMed:Stabilization of emulsion and butter like products containing essential fatty acids using kalonji seeds extract and curcuminoids. |
| PubMed:Anticancer activity of Nigella sativa (black seed) - a review. |
| PubMed:Upregulation of chemoprotective enzymes and glutathione by Nigella sativa (black seed) and thymoquinone in CCl4-intoxicated rats. |
| PubMed:Protective effect of Nigella sativa oil against tramadol-induced tolerance and dependence in mice: role of nitric oxide and oxidative stress. |
| PubMed:Lindane-induced biochemical perturbations in rat serum and attenuation by omega-3 and Nigella sativa seed oil. |
| PubMed:Antiatherogenic Potential of Nigella sativa Seeds and Oil in Diet-Induced Hypercholesterolemia in Rabbits. |
| PubMed:Oleic and linoleic acids are active principles in Nigella sativa and stabilize an E(2)P conformation of the Na,K-ATPase. Fatty acids differentially regulate cardiac glycoside interaction with the pump. |
| PubMed:Various extraction and analytical techniques for isolation and identification of secondary metabolites from Nigella sativa seeds. |
| PubMed:The In Vivo Antidiabetic Activity of Nigella sativa Is Mediated through Activation of the AMPK Pathway and Increased Muscle Glut4 Content. |
| PubMed:Radiosensitization in human breast carcinoma cells by thymoquinone: role of cell cycle and apoptosis. |
| PubMed:Nigella sativa seed extract and its bioactive compound thymoquinone: the new melanogens causing hyperpigmentation in the wall lizard melanophores. |
| PubMed:Antibacterial activity of Thymoquinone, an active principle of Nigella sativa and its potency to prevent bacterial biofilm formation. |
| PubMed:In vitro antituberculous activity of thymoquinone, an active principle of Nigella sativa. |
| PubMed:Determination of oxygen radical absorbance capacity of black cumin (Nigella sativa) seed quinone compounds. |
| PubMed:Investigation of lipids profiles of Nigella, lupin and artichoke seed oils to be used as healthy oils. |
| PubMed:Validated high-performance thin-layer chromatographic method for the quantification of thymoquinone in Nigella Sativa extracts and formulations. |
| PubMed:Phytochemical and biological investigation of the extracts of Nigella sativa L. seed waste. |
| PubMed:In vitro antifungal effect of black cumin seed quinones against dairy spoilage yeasts at different acidity levels. |
| PubMed:The protective effect of thymoquinone against sepsis syndrome morbidity and mortality in mice. |
| PubMed:Chemical composition of Nigella sativa L. seed extracts obtained by supercritical carbon dioxide. |
| PubMed:Amelioration of tamoxifen-induced liver injury in rats by grape seed extract, black seed extract and curcumin. |
| PubMed:Thymoquinone supplementation attenuates cyclophosphamide-induced cardiotoxicity in rats. |
| PubMed:Review on molecular and therapeutic potential of thymoquinone in cancer. |
| PubMed:Protective effects of black cumin (Nigella sativa) oil on TNBS-induced experimental colitis in rats. |
| PubMed:Analgesic effect of Nigella sativa seeds extract on experimentally induced pain in albino mice. |
| PubMed:Nigella sativa L. seed extract modulates the neurotransmitter amino acids release in cultured neurons in vitro. |
| PubMed:Comparative study of Nigella Sativa and triple therapy in eradication of Helicobacter Pylori in patients with non-ulcer dyspepsia. |
| PubMed:Studies on molecular mechanisms of growth inhibitory effects of thymoquinone against prostate cancer cells: role of reactive oxygen species. |
| PubMed:Evaluation of immunomodulatory effect of three herbal plants growing in Egypt. |
| PubMed:Structure-activity studies on therapeutic potential of Thymoquinone analogs in pancreatic cancer. |
| PubMed:Protective effects of Nigella sativa oil and thymoquinone against toxicity induced by the anticancer drug cyclophosphamide. |
| PubMed:Potential adjuvant effects of Nigella sativa seeds to improve specific immunotherapy in allergic rhinitis patients. |
| PubMed:Thymoquinone from nutraceutical black cumin oil activates Neu4 sialidase in live macrophage, dendritic, and normal and type I sialidosis human fibroblast cells via GPCR Galphai proteins and matrix metalloproteinase-9. |
| PubMed:Effect of black seed on dextromethorphan O- and N-demethylation in human liver microsomes and healthy human subjects. |
| PubMed:Radioprotective effects of black seed (Nigella sativa) oil against hemopoietic damage and immunosuppression in gamma-irradiated rats. |
| PubMed:Terpene conjugates of the Nigella sativa seed-oil constituent thymoquinone with enhanced efficacy in cancer cells. |
| PubMed:Thymoquinone-induced relaxation of isolated rat pulmonary artery. |
| PubMed:Induction of apoptosis in HeLa cells by chloroform fraction of seed extracts of Nigella sativa. |
| PubMed:Antimicrobial effect of garlic (Allium sativum). |
| PubMed:Multiple molecular targets underlie the antidiabetic effect of Nigella sativa seed extract in skeletal muscle, adipocyte and liver cells. |
| PubMed:Cellular transport of anti-inflammatory pro-drugs originated from a herbal formulation of Zingiber cassumunar and Nigella sativa. |
| PubMed:Anti-inflammatory effects of the Nigella sativa seed extract, thymoquinone, in pancreatic cancer cells. |
| PubMed:Anti bacterial activity of Nigella sativa against clinical isolates of methicillin resistant Staphylococcus aureus. |
| PubMed:Gastroprotective effect of an aqueous suspension of black cumin Nigella sativa on necrotizing agents-induced gastric injury in experimental animals. |
| PubMed:Ancient nigella seeds from Boyali Höyük in north-central Turkey. |
| PubMed:Effectiveness, safety, and tolerability of powdered Nigella sativa (kalonji) seed in capsules on serum lipid levels, blood sugar, blood pressure, and body weight in adults: results of a randomized, double-blind controlled trial. |
| PubMed:Evaluation of antimicrobial and anti-inflammatory activities of seed extracts from six Nigella species. |
| PubMed:Effects of Nigella sativa seed extract on ameliorating lung tissue damage in rats after experimental pulmonary aspirations. |
| PubMed:Oral and intraperitoneal LD50 of thymoquinone, an active principle of Nigella sativa, in mice and rats. |
| PubMed:Black seed, Nigella sativa, deserves more attention. |
| PubMed:Therapeutic effects of Nigella sativa on chronic HAART-induced hyperinsulinemia in rats. |
| PubMed:Amelioration of chronic relapsing experimental autoimmune encephalomyelitis (cr-eae) using thymoquinone - biomed 2009. |
| PubMed:Comparison of chemical composition and antibacterial activity of Nigella sativa seed essential oils obtained by different extraction methods. |
| PubMed:HIV-1 protease inhibitor induced oxidative stress suppresses glucose stimulated insulin release: protection with thymoquinone. |
| PubMed:Effects of thymoquinone and selenium on the proliferation of mg 63 cells in tissue culture. |
| PubMed:Effect of different levels of feed added black seed (Nigella sativa L.) on the performance of broiler chicks. |
| PubMed:Biological activity of seed aqueous extract of Nigella sativa (L.) on germination and seedling growth of Vigna radiata (L.). |
| PubMed:Black cumin (Nigella sativa L.) supplementation into the diet of the laying hen positively influences egg yield parameters, shell quality, and decreases egg cholesterol. |
| PubMed:From here to eternity - the secret of Pharaohs: Therapeutic potential of black cumin seeds and beyond. |
| PubMed:The possible prophylactic effect of Nigella sativa seed aqueous extract on respiratory symptoms and pulmonary function tests on chemical war victims: a randomized, double-blind, placebo-controlled trial. |
| PubMed:Antihypertensive effect of Nigella sativa seed extract in patients with mild hypertension. |
| PubMed:Attenuation of the development of hypercholesterolemic atherosclerosis by thymoquinone. |
| PubMed:Potentiation of Valproate-induced Anticonvulsant Response by Nigella sativa Seed Constituents: The Role of GABA Receptors. |
| PubMed:The effect of Nigella sativa L. (black cumin seed) on intractable pediatric seizures. |
| PubMed:Cardiac inotropic and hypertrophic effects of Nigella sativa supplementation in rats. |
| PubMed:The possible prophylactic effect of Nigella sativa seed extract in asthmatic patients. |
| PubMed:The secret of the black seed: an ancient healing remedy for the modern healer. |
| PubMed:Anti-tumor properties of blackseed (Nigella sativa L.) extracts. |
| PubMed:A comparison of 5-fluorouracil and natural chemotherapeutic agents, EGCG and thymoquinone, delivered by sustained drug delivery on colon cancer cells. |
| PubMed:Effect of Nigella sativa (Black Seed) and thymoquinone on blood glucose in albino rats. |
| PubMed:Assessment of cellular responses to oxidative stress using MCF-7 breast cancer cells, black seed (N. Sativa L.) extracts and H2O2. |
| PubMed:Comparison of potential chemotherapeutic agents, 5-fluoruracil, green tea, and thymoquinone on colon cancer cells. |
| PubMed:An investigation of the analgesic and anti-inflammatory effects of Nigella sativa seed polyphenols. |
| PubMed:Immunomodulatory and therapeutic properties of the Nigella sativa L. seed. |
| PubMed:Immunomodulating effects of black seed and oxytetracycline in pigeons. |
| PubMed:Nigella sativa (black seed) oil does not affect the T-helper 1 and T-helper 2 type cytokine production from splenic mononuclear cells in allergen sensitized mice. |
| PubMed:An investigation on LD50 and subacute hepatic toxicity of Nigella sativa seed extracts in mice. |
| PubMed:Antidermatophyte activity of ether extract of Nigella sativa and its active principle, thymoquinone. |
| PubMed:The effects of isolated antioxidants from black seed on the cellular metabolism of A549 cells. |
| PubMed:Floral costs in Nigella sativa (Ranunculaceae): compensatory responses to perianth removal. |
| PubMed:Inhibition of 5-lipoxygenase and leukotriene C4 synthase in human blood cells by thymoquinone. |
| PubMed:Determination of isopropylmethylphenols in black seed oil by differential pulse voltammetry. |
| PubMed:Nigella sativa seed extracts enhance glucose-induced insulin release from rat-isolated Langerhans islets. |
| PubMed:Thymoquinone extracted from black seed triggers apoptotic cell death in human colorectal cancer cells via a p53-dependent mechanism. |
| PubMed:Effects of sustained delivery of thymoqiunone on bone healing of male rats. |
| PubMed:Black cumin seed essential oil, as a potent analgesic and antiinflammatory drug. |
| PubMed:Thymoquinone and Nigella sativa oil protection against methionine-induced hyperhomocysteinemia in rats. |
| PubMed:Effects of Nigella sativa L. and Urtica dioica L. on selected mineral status and hematological values in CCl4-treated rats. |
| PubMed:Effect of Nigella sativa (black seed) on subjective feeling in patients with allergic diseases. |
| PubMed:Radical scavenging activity of black cumin (Nigella sativa L.), coriander (Coriandrum sativum L.), and niger (Guizotia abyssinica Cass.) crude seed oils and oil fractions. |
| PubMed:A simple differential pulse polarographic method for the determination of thymoquinone in black seed oil. |
| PubMed:Thymoquinone-induced relaxation of guinea-pig isolated trachea. |
| PubMed:The role of black seed in the proliferation and biochemical marker levels of Hep-2 cells. |
| PubMed:Delayed apoptosis upon the treatment of Hep-2 cells with black seed. |
| PubMed:Pharmacological and toxicological properties of Nigella sativa. |
| PubMed:Characterization of phospholipid composition of black cumin (Nigella sativa L.) seed oil. |
| PubMed:Response of broiler chicks to dietary Rhazya stricta and Nigella sativa. |
| PubMed:Cytogenetic studies on Nigella sativa seeds extract and thymoquinone on mouse cells infected with schistosomiasis using karyotyping. |
| PubMed:Effects of Nigella sativa fixed oil on blood homeostasis in rat. |
| PubMed:Inhibitory effects of thymoquinone against 20-methylcholanthrene-induced fibrosarcoma tumorigenesis. |
| PubMed:Protective effect of black seed oil from Nigella sativa against murine cytomegalovirus infection. |
| PubMed:High performance liquid chromatographic analysis of the pharmacologically active quinones and related compounds in the oil of the black seed (Nigella sativa L.). |
| PubMed:Inhibition of benzo(a)pyrene-induced forestomach carcinogenesis in mice by thymoquinone. |
| PubMed:The in vitro anti-tumor activity of some crude and purified components of blackseed, Nigella sativa L. |
| PubMed:Protective effect of cysteine and vitamin E, Crocus sativus and Nigella sativa extracts on cisplatin-induced toxicity in rats. |
| PubMed:The cardiovascular actions of the volatile oil of the black seed (Nigella sativa) in rats: elucidation of the mechanism of action. |
| PubMed:The respiratory effects of the volatile oil of the black seed (Nigella sativa) in guinea-pigs: elucidation of the mechanism(s) of action. |
| PubMed:Studies on the antimicrobial activity of Nigella sativa seed (black cumin). |
| PubMed:Modulatory effects of Crocus sativus and Nigella sativa extracts on cisplatin-induced toxicity in mice. |
| PubMed:Sterols in the seed oil of Nigella sativa. |