epimedium koreanum extract
extract of the whole plant, epimedium koreanum, berberidaceae
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Category: antimicrobial agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Physical Properties:
Food Chemicals Codex Listed: No
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Organoleptic Properties:
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: antimicrobial agents
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 None found
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Safety Information:
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: antimicrobial agents
Recommendation for epimedium koreanum extract usage levels up to:
 not for fragrance use.
Recommendation for epimedium koreanum extract flavor usage levels up to:
 not for flavor use.
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Safety References:
None found
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Other Information:
Wikipedia: View
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Potential Blenders and core components note
None Found
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 epimedium koreanum
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 extract of the whole plant, epimedium koreanum, berberidaceae
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PubMed: 2-Phenoxychromones and Prenylflavonoids from Epimedium koreanum and Their Inhibitory Effects on LPS-Induced Nitric Oxide and Interleukin-1β Production.
J-Stage: High-Performance Liquid Chromatography-Based Multivariate Analysis to Predict the Estrogenic Activity of an Epimedium koreanum Extract
PubMed: Combined treatment with Epimedium koreanum Nakai extract and gefitinib overcomes drug resistance caused by T790M mutation in non-small cell lung cancer cells.
PubMed: Comparative studies on antioxidant activities of extracts and fractions from the leaves and stem of Epimedium koreanum Nakai.
PubMed: A comparative study on the metabolism of Epimedium koreanum Nakai-prenylated flavonoids in rats by an intestinal enzyme (lactase phlorizin hydrolase) and intestinal flora.
PubMed: An integrated plasma and urinary metabonomic study using UHPLC-MS: intervention effects of Epimedium koreanum on 'Kidney-Yang Deficiency syndrome' rats.
PubMed: Epimedium koreanum Nakai Water Extract Exhibits Antiviral Activity against Porcine Epidermic Diarrhea Virus In Vitro and In Vivo.
PubMed: Immunoadjuvant activity of icariin that induces Th1-type antibody in mice.
PubMed: Maohuoside A acts in a BMP-dependent manner during osteogenesis.
PubMed: Epimedium koreanum Extract and Its Constituent Icariin Improve Motor Dysfunction in Spinal Cord Injury.
PubMed: Epimediphine, a novel alkaloid from Epimedium koreanum inhibits acetylcholinesterase.
PubMed: High-performance liquid chromatography-based multivariate analysis to predict the estrogenic activity of an Epimedium koreanum extract.
PubMed: Reactive oxygen species-mediated mitochondrial pathway is involved in Baohuoside I-induced apoptosis in human non-small cell lung cancer.
PubMed: Estrogenic/antiestrogenic activities of a Epimedium koreanum extract and its major components: in vitro and in vivo studies.
PubMed: Icariside II induces apoptosis in U937 acute myeloid leukemia cells: role of inactivation of STAT3-related signaling.
PubMed: Maohuoside A promotes osteogenesis of rat mesenchymal stem cells via BMP and MAPK signaling pathways.
PubMed: Permanent genetic resources added to Molecular Ecology Resources Database 1 August 2010-30 September 2010.
PubMed: Synergistic or antagonistic effect of MTE plus TF or icariin from Epimedium koreanum on the proliferation and differentiation of primary osteoblasts in vitro.
PubMed: [Molecular authentication of medicinal Epimedium species--a case of diagnostic PCR authentication of Epimedium koreanum].
PubMed: Inhibition of osteoclastogenic differentiation by Ikarisoside A in RAW 264.7 cells via JNK and NF-kappaB signaling pathways.
PubMed: Identification of prenyl flavonoid glycosides and phenolic acids in Epimedium koreanum Nakai by Q-TOF-MS combined with selective enrichment on "click oligo (ethylene glycol)" column.
PubMed: Two new flavonol glycosides from Epimedium koreanum Nakai.
PubMed: Cyclooxygenase-2/prostaglandin E2 pathway mediates icariside II induced apoptosis in human PC-3 prostate cancer cells.
PubMed: Ikarisoside A inhibits inducible nitric oxide synthase in lipopolysaccharide-stimulated RAW 264.7 cells via p38 kinase and nuclear factor-kappaB signaling pathways.
PubMed: Icariin stimulates angiogenesis by activating the MEK/ERK- and PI3K/Akt/eNOS-dependent signal pathways in human endothelial cells.
PubMed: Identification and characterization of active compounds and their metabolites by high-performance liquid chromatography/Fourier transform ion cyclotron resonance mass spectrometry after oral administration of a herbal extract of Epimedium koreanum Nakai to rats.
PubMed: Intestinal absorption mechanisms of prenylated flavonoids present in the heat-processed Epimedium koreanum Nakai (Yin Yanghuo).
PubMed: Determination of icariin in rat plasma by reverse-phase high-performance liquid chromatography after oral administration of a lipid-based suspension of Epimedium koreanum extract.
PubMed: Icariside II from Epimedium koreanum inhibits hypoxia-inducible factor-1alpha in human osteosarcoma cells.
PubMed: Effect of lipid-based suspension of Epimedium koreanum Nakai extract on sexual behavior in rats.
PubMed: [Comparison of antioxidative and antitumor activities of six flavonoids from Epimedium koreanum].
PubMed: In vitro cytotoxic activity of some Korean medicinal plants on human cancer cell lines: enhancement in cytotoxicity by heat processing.
PubMed: Effects of total flavonoids and flavonol glycosides from Epimedium koreanum Nakai on the proliferation and differentiation of primary osteoblasts.
PubMed: Comparison between HPLC and HPTLC densitometry for the determination of icariin from Epimedium koreanum extracts.
PubMed: [Identification of Epimedium Koreanum Nakai by Fourier transfer infrared spectroscopy].
PubMed: Structure identification of a prenylflavonol glycoside from Epimedium koreanum by electrospray ionization tandem mass spectrometry.
PubMed: [Study on extraction total flavonoids in Epimedium koreanum using high pressure technology].
PubMed: Screening of Korean herbal medicines used to improve cognitive function for anti-cholinesterase activity.
PubMed: Neuritogenesis of herbal (+)- and (-)-syringaresinols separated by chiral HPLC in PC12h and Neuro2a cells.
PubMed: [The chemical constituents of Epimedium koreanum Nakai].
PubMed: [Determination of icariin in Epimedium koreanum nakai by high performance liquid chromatography].
PubMed: [Effects of icariin on the differentiation of HL-60 cells].
PubMed: [Quantitative study of magnoflorine in Epimedium koreanum Nakai].
PubMed: Anhydroicaritin 3-O-rhamnosyl(1-->2)rhamnoside from epimedium koreanum and a reappraisal of other rhamnosyl(1-->2, 1-->3 and 1-->4)rhamnoside structures.
PubMed: [Determination of chlorogenic acid in Epimedium koreanum Nakai by HPLC].
PubMed: [Quantitative changes of flavonoids in Epimedium koreanum Nakai in different collecting periods].
PubMed: [Structure determination of korepimedoside A and korepimedoside B from Epimedium koreanum Nakai].
PubMed: Antihepatotoxic activity of icariin, a major constituent of Epimedium koreanum.
PubMed: [Determination of hyperin in Epimedium koreanum Nakai by HPLC].
PubMed: Flavonol glycosides from Epimedium koreanum.
PubMed: [Effect of flavone glycosides of Epimedium koreanum on murine fibrinolytic system and apoplectic mortality].
PubMed: [New Prenylflavonoid Glycosides from Epimedium koreanum].
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