epimedium sagittatum leaf/stem extract
extract of the leaves and stems of epimedium sagittatum, berberidaceae
None found
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Category: cosmetic and flavor agents, dietary supplements
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Physical Properties:
Food Chemicals Codex Listed: No
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Organoleptic Properties:
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: antioxidants
flavoring agents
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Horny Goat Weed Extract
NAT healthy™
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Safety Information:
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: cosmetic and flavor agents, dietary supplements
Recommendation for epimedium sagittatum leaf/stem extract usage levels up to:
 not for fragrance use.
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Safety References:
None found
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None found
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Other Information:
Wikipedia: View
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Potential Blenders and core components note
None Found
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 epimedium sagittatum
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 extract of the leaves and stems of epimedium sagittatum, berberidaceae
 horny goat weed leaf/stem extract
 yin yang huo leaf/stem extract
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PubMed: Functional and evolutionary analysis of the AP1/SEP/AGL6 superclade of MADS-box genes in the basal eudicot Epimedium sagittatum.
PubMed: A R2R3-MYB transcription factor from Epimedium sagittatum regulates the flavonoid biosynthetic pathway.
PubMed: First Insights into the Large Genome of Epimedium sagittatum (Sieb. et Zucc) Maxim, a Chinese Traditional Medicinal Plant.
PubMed: Herb-drug interaction of Epimedium sagittatum (Sieb. et Zucc.) maxim extract on the pharmacokinetics of sildenafil in rats.
PubMed: Icariin delays homocysteine-induced endothelial cellular senescence involving activation of the PI3K/AKT-eNOS signaling pathway.
PubMed: Characterization of a Crabs Claw Gene in Basal Eudicot Species Epimedium sagittatum (Berberidaceae).
PubMed: Isolation and Molecular Characterization of Thirteen R2R3-MYB Transcription Factors from Epimedium sagittatum.
PubMed: Variation of medicinal components in a unique geographical accession of horny goat weed Epimedium sagittatum Maxim. (Berberidaceae).
PubMed: Icariin inhibits corticosterone-induced apoptosis in hypothalamic neurons via the PI3-K/Akt signaling pathway.
PubMed: Isolation and molecular characterisation of flavonoid 3'-hydroxylase and flavonoid 3', 5'-hydroxylase genes from a traditional Chinese medicinal plant, Epimedium sagittatum.
PubMed: Icaritin induces cell death in activated hepatic stellate cells through mitochondrial activated apoptosis and ameliorates the development of liver fibrosis in rats.
PubMed: Permanent genetic resources added to Molecular Ecology Resources Database 1 August 2010-30 September 2010.
PubMed: Effects of total flavonoids of Epimedium sagittatum on the mRNA expression of the estrogen receptor α and β in hypothalamus and hippocampus in ovariectomized rats.
PubMed: Neuroprotective effects of icariin on corticosterone-induced apoptosis in primary cultured rat hippocampal neurons.
PubMed: Development of a EST dataset and characterization of EST-SSRs in a traditional Chinese medicinal plant, Epimedium sagittatum (Sieb. Et Zucc.) Maxim.
PubMed: [The contents changes of polysaccharides and total flavonoids during flower bud differentiation of Epimedium sagittatum].
PubMed: Virtual screening and drug design for PDE-5 receptor from traditional Chinese medicine database.
PubMed: Computational screening and design of traditional Chinese medicine (TCM) to block phosphodiesterase-5.
PubMed: Discovery of potent inhibitors for phosphodiesterase 5 by virtual screening and pharmacophore analysis.
PubMed: [Effects of rat serum containing total flavonoid extract of Epimedium sagittatum on development of osteoblasts].
PubMed: Fourteen microsatellite loci for the Chinese medicinal plant Epimedium sagittatum and cross-species application in other medicinal species.
PubMed: Icariin enhances the osteogenic differentiation of bone marrow stromal cells but has no effects on the differentiation of newborn calvarial osteoblasts of rats.
PubMed: Prenylflavonol, acylated flavonol glycosides and related compounds from Epimedium sagittatum.
PubMed: Neuroprotective effects of icaritin against beta amyloid-induced neurotoxicity in primary cultured rat neuronal cells via estrogen-dependent pathway.
PubMed: Molecular mechanism of cell cycle blockage of hepatoma SK-Hep-1 cells by Epimedin C through suppression of mitogen-activated protein kinase activation and increased expression of CDK inhibitors p21(Cip1) and p27(Kip1).
PubMed: [Comment on main species of herba epimedii].
PubMed: Angiogenesis and anti-angiogenesis activity of Chinese medicinal herbal extracts.
PubMed: The serum of rats administered flavonoid extract from Epimedium sagittatum but not the extract itself enhances the development of rat calvarial osteoblast-like cells in vitro.
PubMed: Cytotoxic effects of Coptis chinensis and Epimedium sagittatum extracts and their major constituents (berberine, coptisine and icariin) on hepatoma and leukaemia cell growth.
PubMed: Flavonol glycosides from Epimedium sagittatum and their neurite outgrowth activity on PC12h cells.
PubMed: New prenylflavones from the leaves of Epimedium saggitatum.
PubMed: [Effect of Epimedium sagittatum on quality of life and cellular immunity in patients of hemodialysis maintenance].
PubMed: [Effect of epimedium sagittatum on soluble IL-2 receptor and IL-6 levels in patients undergoing hemodialysis].
PubMed: [Effects of Epimedium sagittatum on immunopathology and extracellular matrices in rats with chronic renal insufficiency].
PubMed: [Effects of Epimedium sagittatum Maxim. Polysaccharides on DNA synthesis of bone marrow cells of "yang deficiency" animal model caused by hydroxyurea].
PubMed: [Phagocytic activity of leaves of Epimedium species on mouse reticuloendotherial system].
PubMed: Sagittatins A and B, Flavonoid Glycosides of Epimedium sagittatum Herbs1.
PubMed: An experimental study of the anti-HSV-II action of 500 herbal drugs.
PubMed: [Stimulatory action of Epimedium sagittatum (Sieb. et Zucc.) Maxim. on platelet aggregation in rats].
PubMed: [The treatment of leucopenia with inspissated granula of Epimedium sagittatum and its effects on serum Zn, Cu and Mg].
PubMed: [Effects of Epimedium sagittatum and Cistanche deserticola on DNA synthesis in "Yang-insufficiency" animal model induced by hydroxyurea].
PubMed: [Studies on the flavonoids of Epimedium sagittatum (author's transl)].
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