camellia sinensis catechins
mixture of catechins obtained from the leaves of tea, camellia sinensis, theaceae
 
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Name: camellia sinensis l. catechins
CAS Number: 84650-60-2 
ECHA EC Number: 283-519-7
Category: fragrance agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Physical Properties:
Food Chemicals Codex Listed: No
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Organoleptic Properties:
  
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: antioxidants
perfuming agents
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Suppliers:
 None found
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: fragrance agents
IFRA Critical Effect: Sensitization
IFRA: View Standard
Fragrance usage is IFRA RESTRICTED. View Standard for complete information.
Please review all IFRA documents for complete information.
IFRA categories: limits in the finished product: (For a description of the categories, refer to the IFRA QRA Information Booklet.)
Category 1:
See Note (1)
0.01 % (1)
Category 2:  0.02 %
Category 3:  0.07 %
Category 4:  0.20 %
Category 5:  0.10 %
Category 6:  0.30 % (1)
Category 7:  0.04 %
Category 8:  0.50 %
Category 9:  2.40 %
Category 10:  2.50 %
Category 11: See Note (2)
 Notes:
 

(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry). Further information about IOFI can be found on its website (www.iofi.org).

 

(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.

 
Recommendation for camellia sinensis catechins flavor usage levels up to:
 not for flavor use.
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Safety References:
Chemical Carcinogenesis Research Information System: Search
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
National Institute of Allergy and Infectious Diseases: Data
 camellia sinensis l. catechins
Chemidplus: 084650602
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References:
 camellia sinensis l. catechins
Pubchem (sid): 135275029
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Other Information:
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 tea catechins
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Synonyms:
 camellia thea catechins
 mixture of catechins obtained from the leaves of tea, camellia sinensis, theaceae
 thea assamica catechins
 thea sinensis catechins
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Articles:
PubMed: Changes of major tea polyphenols and production of four new B-ring fission metabolites of catechins from post-fermented Jing-Wei Fu brick tea.
PubMed: Determination of catechin content in representative chinese tea germplasms.
PubMed: A review on the structure-function relationship aspect of polysaccharides from tea materials.
PubMed: Effects of water availability and pest pressures on tea (Camellia sinensis) growth and functional quality.
PubMed: Effects of fertilizing with N, p, se, and zn on regulating the element and functional component contents and antioxidant activity of tea leaves planted in red soil.
PubMed: The characterization of caffeine and nine individual catechins in the leaves of green tea (Camellia sinensis L.) by near-infrared reflectance spectroscopy.
PubMed: Interactions among chemical components of Cocoa tea (Camellia ptilophylla Chang), a naturally low caffeine-containing tea species.
PubMed: Determination of quality constituents in the young leaves of albino tea cultivars.
PubMed: Catechin concentrates of garden tea leaves (Camellia sinensis L.): extraction/isolation and evaluation of chemical composition.
PubMed: Effects of single dose and regular intake of green tea (Camellia sinensis) on DNA damage, DNA repair, and heme oxygenase-1 expression in a randomized controlled human supplementation study.
PubMed: Black tea polyphenols: a mechanistic treatise.
PubMed: The role of green tea extract and powder in mitigating metabolic syndromes with special reference to hyperglycemia and hypercholesterolemia.
PubMed: Effects of season and plantation on phenolic content of unfermented and fermented Sri Lankan tea.
PubMed: 8-C N-ethyl-2-pyrrolidinone substituted flavan-3-ols as the marker compounds of Chinese dark teas formed in the post-fermentation process provide significant antioxidative activity.
PubMed: Acute effects of green tea extract intake on exogenous and endogenous metabolites in human plasma.
PubMed: Estimation of tea catechin levels using micellar electrokinetic chromatography: a quantitative approach.
PubMed: Analytical determination of flavonoids aimed to analysis of natural samples and active packaging applications.
PubMed: Identification of native catechin fatty acid esters in green tea (Camellia sinensis).
PubMed: Rapid tea catechins and caffeine determination by HPLC using microwave-assisted extraction and silica monolithic column.
PubMed: Epicatechin and epigallocatechin gallate inhibit formation of intermediary radicals during heating of lysine and glucose.
PubMed: Improving the capacity of polypropylene to be used in antioxidant active films: incorporation of plasticizer and natural antioxidants.
PubMed: Effects of green tea extract and (-)-epigallocatechin-3-gallate on pharmacokinetics of nadolol in rats.
PubMed: The relationship between the structure and biological actions of green tea catechins.
PubMed: Green tea from purple leaf coloured tea clones in Kenya- their quality characteristics.
PubMed: Bioactive-rich Sideritis scardica tea (mountain tea) is as potent as Camellia sinensis tea at inducing cellular antioxidant defences and preventing oxidative stress.
PubMed: Green tea extract with polyethylene glycol-3350 reduces body weight and improves glucose tolerance in db/db and high-fat diet mice.
PubMed: Dose-response plasma appearance of green tea catechins in adults.
PubMed: Flavonol glycosides with lipid accumulation inhibitory activity and simultaneous quantitative analysis of 15 polyphenols and caffeine in the flower buds of Camellia sinensis from different regions by LCMS.
PubMed: Oral green tea catechins transiently lower plasma glucose concentrations in female db/db mice.
PubMed: Human clinical studies of tea polyphenols in allergy or life style-related diseases.
PubMed: Analysis of some selected catechins and caffeine in green tea by high performance liquid chromatography.
PubMed: Redox properties of catechins and enriched green tea extracts effectively preserve L-5-methyltetrahydrofolate: assessment using cyclic voltammetry analysis.
PubMed: Catechins are not major components responsible for the beneficial effect of Camellia sinensis on the ovarian δ-ALA-D activity inhibited by cadmium.
PubMed: Total polyphenols, catechin profiles and antioxidant activity of tea products from purple leaf coloured tea cultivars.
PubMed: Rapid and simultaneous determination of antioxidant markers and caffeine in commercial teas and dietary supplements by HPLC-DAD.
PubMed: Evaluation of Camellia sinensis catechins as a swine antimicrobial feed additive that does not cause antibiotic resistance.
PubMed: Polyphenols extracted from black tea (Camellia sinensis) residue by hot-compressed water and their inhibitory effect on pancreatic lipase in vitro.
PubMed: Role of catechins in the antioxidant capacity of an active film containing green tea, green coffee, and grapefruit extracts.
PubMed: Hypoglycemic effect of the water extract of Pu-erh tea.
PubMed: Beneficial effects of polyphenol-rich olive oil in patients with early atherosclerosis.
PubMed: Discrimination of the production season of Chinese green tea by chemical analysis in combination with supervised pattern recognition.
PubMed: The impact of the catechol-O-methyltransferase genotype on vascular function and blood pressure after acute green tea ingestion.
PubMed: Grape seed and tea extracts and catechin 3-gallates are potent inhibitors of α-amylase and α-glucosidase activity.
PubMed: Engineering the production of major catechins by Escherichia coli carrying metabolite genes of Camellia sinensis.
PubMed: Chemical analysis and acetylcholinesterase inhibitory effect of anthocyanin-rich red leaf tea (cv. Sunrouge).
PubMed: Inhibition of acetylcholinesterase by green and white tea and their simulated intestinal metabolites.
PubMed: Evaluation of green tea extract as a glazing material for shrimp frozen by cryogenic freezing.
PubMed: Epicatechin-3-O-(3″-O-methyl)-gallate content in various tea cultivars (Camellia sinensis L.) and its in vitro inhibitory effect on histamine release.
PubMed: Isolation and identification of spermidine derivatives in tea (Camellia sinensis) flowers and their distribution in floral organs.
PubMed: Development and certification of green tea-containing standard reference materials.
PubMed: AFM study of the differential inhibitory effects of the green tea polyphenol (-)-epigallocatechin-3-gallate (EGCG) against Gram-positive and Gram-negative bacteria.
PubMed: Metabolic dependence of green tea on plucking positions revisited: a metabolomic study.
PubMed: A subacute toxicity evaluation of green tea (Camellia sinensis) extract in mice.
PubMed: Effect of milk and brewing method on black tea catechin bioaccessibility.
PubMed: Development of new antioxidant active packaging films based on ethylene vinyl alcohol copolymer (EVOH) and green tea extract.
PubMed: Green and black tea in relation to gynecologic cancers.
PubMed: Mechanistic issues concerning cancer prevention by tea catechins.
PubMed: Ten marker compounds-based comparative study of green tea and guava leaf by HPTLC densitometry methods: antioxidant activity profiling.
PubMed: Extraction of antioxidants and caffeine from green tea (Camelia sinensis) leaves: kinetics and modeling.
PubMed: Increased plasma concentration of epigallocatechin in mice after orally administering a green tea (Camellia sinensis L.) extract supplemented by steamed rice.
PubMed: Effect of green tea powder (Camellia sinensis L. cv. Benifuuki) particle size on O-methylated EGCG absorption in rats; The Kakegawa Study.
PubMed: Weight control and prevention of metabolic syndrome by green tea.
PubMed: The impact of the catechol-O-methyltransferase genotype on the acute responsiveness of vascular reactivity to a green tea extract.
PubMed: Determination of catechins and caffeine in proposed green tea standard reference materials by liquid chromatography-particle beam/electron ionization mass spectrometry (LC-PB/EIMS).
PubMed: Effects of cellulase from Aspergillus niger and solvent pretreatments on the extractability of organic green tea waste.
PubMed: White and green teas (Camellia sinensis var. sinensis): variation in phenolic, methylxanthine, and antioxidant profiles.
PubMed: Green tea extract-patents and diversity of uses.
PubMed: Recent patents on Camellia sinensis: source of health promoting compounds.
PubMed: Preventive effects of black tea theaflavins against mouse type IV allergy.
PubMed: Beta-cyclodextrin/surface plasmon resonance detection system for sensing bitter-astringent taste intensity of green tea catechins.
PubMed: The antioxidant and pro-oxidant activities of green tea polyphenols: a role in cancer prevention.
PubMed: Identification of alpha-glucosidase inhibitors from a new fermented tea obtained by tea-rolling processing of loquat (Eriobotrya japonica) and green tea leaves.
PubMed: Diversity among various forms of catechins and its synthesizing enzyme (phenylalanine ammonia lyase) in relation to quality of black tea (Camellia spp.).
PubMed: Antihypertensive effect of Benifuuki tea containing O-methylated EGCG.
PubMed: Hypochromic effect of an aqueous monoglucosyl rutin solution caused by green tea catechins.
PubMed: Tea catechins induce the conversion of preformed lysozyme amyloid fibrils to amorphous aggregates.
PubMed: Tea catechins' affinity for human cannabinoid receptors.
PubMed: Identification of a major polyphenol and polyphenolic composition in leaves of Camellia irrawadiensis.
PubMed: Investigation of the site-specific accumulation of catechins in the tea plant (Camellia sinensis (L.) O. Kuntze) via vanillin-HCl staining.
PubMed: Greeen tea extracts lower serum folates in rats at very high dietary concentrations only and do not affect plasma folates in a human pilot study.
PubMed: Green tea (Camellia sinensis) catechins and vascular function.
PubMed: Effects of catechin enriched green tea on body composition.
PubMed: Long-term green tea catechin administration prevents spatial learning and memory impairment in senescence-accelerated mouse prone-8 mice by decreasing Abeta1-42 oligomers and upregulating synaptic plasticity-related proteins in the hippocampus.
PubMed: Increase of theaflavin gallates and thearubigins by acceleration of catechin oxidation in a new fermented tea product obtained by the tea-rolling processing of loquat ( Eriobotrya japonica ) and green tea leaves.
PubMed: Preparation and antioxidant activity of green tea extract enriched in epigallocatechin (EGC) and epigallocatechin gallate (EGCG).
PubMed: Determination of total catechins in tea extracts by HPLC and spectrophotometry.
PubMed: In vitro anti-adhesive activity of green tea extract against pathogen adhesion.
PubMed: High-throughput technique for comprehensive analysis of Japanese green tea quality assessment using ultra-performance liquid chromatography with time-of-flight mass spectrometry (UPLC/TOF MS).
PubMed: Identification of green tea's (Camellia sinensis (L.)) quality level according to measurement of main catechins and caffeine contents by HPLC and support vector classification pattern recognition.
PubMed: Inhibition of pectin methyl esterase activity by green tea catechins.
PubMed: Green tea catechin enhances cholesterol 7alpha-hydroxylase gene expression in HepG2 cells.
PubMed: Evaluation of toxicity of green tea catechins with 90-day dietary administration to F344 rats.
PubMed: Temporal changes in aroma release of Longjing tea infusion: interaction of volatile and nonvolatile tea components and formation of 2-butyl-2-octenal upon aging.
PubMed: Changes in the concentrations of acrylamide, selected odorants, and catechins caused by roasting of green tea.
PubMed: Influence of epigallocatechin gallate and phenolic compounds from green tea on the growth of Oenococcus oeni.
PubMed: Preparation of partially decaffeinated instant green tea.
PubMed: Study on the antioxidant activity of tea flowers (Camellia sinensis).
PubMed: Structure-activity relationships of tea compounds against human cancer cells.
PubMed: Green tea extract thermogenesis-induced weight loss by epigallocatechin gallate inhibition of catechol-O-methyltransferase.
PubMed: Determination of the predominant catechins in Acacia catechu by liquid chromatography/electrospray ionization-mass spectrometry.
PubMed: Modulation of cholesterol metabolism by the green tea polyphenol (-)-epigallocatechin gallate in cultured human liver (HepG2) cells.
PubMed: Catechin and caffeine content of green tea dietary supplements and correlation with antioxidant capacity.
PubMed: Effect of far-infrared irradiation on catechins and nitrite scavenging activity of green tea.
PubMed: Catechin transformation as influenced by aluminum.
PubMed: Analytical separation of tea catechins and food-related polyphenols by high-speed counter-current chromatography.
PubMed: HPLC analysis of naturally occurring methylated catechins, 3' '- and 4' '-methyl-epigallocatechin gallate, in various fresh tea leaves and commercial teas and their potent inhibitory effects on inducible nitric oxide synthase in macrophages.
PubMed: Seasonal variations of phenolic compounds in Australia-grown tea (Camellia sinensis).
PubMed: The apoptotic effect of green tea (-)-epigallocatechin gallate on 3T3-L1 preadipocytes depends on the Cdk2 pathway.
PubMed: [Determination of catechins and caffeine in tea and tea beverages by high-performance liquid chromatography].
PubMed: Antimicrobial properties of green tea catechins.
PubMed: Stability of tea catechins in the breadmaking process.
PubMed: Polyphenolic compounds, antioxidant capacity, and quinone reductase activity of an aqueous extract of Ardisia compressa in comparison to mate (Ilex paraguariensis) and green (Camellia sinensis) teas.
PubMed: Tissue distribution and intracellular localization of catechins in tea leaves.
PubMed: Capillary electrophoretic determination of theanine, caffeine, and catechins in fresh tea leaves and oolong tea and their effects on rat neurosphere adhesion and migration.
PubMed: A combination of tea (Camellia senensis) catechins is required for optimal inhibition of induced CYP1A expression by green tea extract.
PubMed: Determination of peroxyl radical scavenging activity of flavonoids and plant extracts using an automatic potentiometric titrator.
PubMed: Factors affecting the levels of tea polyphenols and caffeine in tea leaves.
PubMed: Determination of tea polyphenols and caffeine in tea flowers (Camellia sinensis) and their hydroxyl radical scavenging and nitric oxide suppressing effects.
PubMed: Green tea upregulates the low-density lipoprotein receptor through the sterol-regulated element binding Protein in HepG2 liver cells.
PubMed: Inhibitory effects of tea catechins and O-methylated derivatives of (-)-epigallocatechin-3-O-gallate on mouse type IV allergy.
PubMed: Preparative separation of polyphenols from tea by high-speed countercurrent chromatography.
PubMed: Application of near-infrared reflectance spectroscopy to the simultaneous prediction of alkaloids and phenolic substances in green tea leaves.
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