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phyllanthus emblica fruit extract
extract of the fruit of phyllanthus emblica l., euphorbiaceae

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Name:phyllanthus emblica l. fruit extract
CAS Number: 90028-28-7
ECHA EC Number:289-817-3
FDA UNII: Search
Category:cosmetic agents, dietary supplements
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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 FDA/DG SANTE Petitions, Reviews, Notices:
GRN 322 Aqueous extract of Emblica officinalis View - notice PDF
GRN 295 Aqueous extract of Emblica officinalis View - notice PDF
GRN 483 Aqueous extract of Emblica officinalis View - notice PDF
FEMA Number:4955
FDA:No longer provide for the use of these seven synthetic flavoring substances
 
Physical Properties:
Food Chemicals Codex Listed: No
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data2
CosIng:cosmetic data
Cosmetic Uses: humectants
skin conditioning
 
Suppliers:
AuNutra® Industries
Emblica Officinalis Extract
Carrubba
amalaki extract
Charkit Chemical
AMLA EXTRACT 20% TANNINS
Charkit Chemical
AMLA EXTRACT 30% TANNINS
Indo World Trading
Phyllanthus Emblica Fruit Extract
Sabinsa Corporation
Amla (Saberry®)
Shaanxi Y-Herb Biotechnology
Phyllanthus Emblica Herbal Extract Powder Gooseberry Amla Berry Fruit Extract Powder
Silverline Chemicals
Gooseberry Extract (Emblica officinalis) Polyphenols & Ascorbic acid
Symrise
Actipone®Amla (Amalki) Fruit GW
Life Essentials - Botanicals
Odor: characteristic
Use: Actipone® Amla (Amalki) Fruit GW contains an extract of amla fruits, prepared in water and glycerin and is preserved. Amalki has been traditionally used in Ayurveda. Amla (Emblica Officinalis) used for our Actipone® is mainly cultivated in India. The fruits are harvested, cleaned and if necessary comminuted, dried, aqueously extracted and filtrated. The filtrate is concentrated by evaporation and carefully spray-dried. The concentrated amla fruit extract is prepared in a mixture of water, glycerin and preservatives and filtrated after an individual ripening time. 1 kg Actipone® Amla (Amalki) Fruit GW contains the water-soluble ingredients of approx. 120 g dried respectively of approx. 900 g fresh amla fruits. Plant material - extract - ratio 0.12:1. Fresh plant material - extract – ratio 0.90:1 Actipone® Amla (Amalki) Fruit GW shows anti-oxidant properties (in vitro).
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
cosmetic agents, dietary supplements
Recommendation for phyllanthus emblica fruit extract usage levels up to:
 not for fragrance use.
 
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 30
Click here to view publication 30
 average usual ppmaverage maximum ppm
baked goods: 50.00000200.00000
beverages(nonalcoholic): 30.00000100.00000
beverages(alcoholic): 30.00000100.00000
breakfast cereal: 50.00000200.00000
cheese: 50.00000200.00000
chewing gum: 100.00000300.00000
condiments / relishes: 50.00000200.00000
confectionery froastings: 50.00000200.00000
egg products: 50.00000200.00000
fats / oils: 50.00000100.00000
fish products: 50.00000200.00000
frozen dairy: 50.00000150.00000
fruit ices: 20.00000100.00000
gelatins / puddings: 20.00000100.00000
granulated sugar: --
gravies: 50.00000200.00000
hard candy: 100.00000300.00000
imitation dairy: 50.00000300.00000
instant coffee / tea: 50.00000200.00000
jams / jellies: 20.00000150.00000
meat products: 50.00000300.00000
milk products: 50.00000150.00000
nut products: 50.00000200.00000
other grains: 50.00000300.00000
poultry: 50.00000300.00000
processed fruits: 30.00000200.00000
processed vegetables: 50.00000300.00000
reconstituted vegetables: 50.00000300.00000
seasonings / flavors: 50.00000200.00000
snack foods: 50.00000200.00000
soft candy: 100.00000300.00000
soups: 50.00000200.00000
sugar substitutes: 20.00000100.00000
sweet sauces: 20.00000200.00000
 
Safety References:
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
National Institute of Allergy and Infectious Diseases:Data
phyllanthus emblica l. fruit extract
Chemidplus:0090028287
 
References:
 phyllanthus emblica l. fruit extract
Pubchem (sid):135290837
 
Other Information:
FDA Listing of Food Additive Status:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 phyllanthus emblica fruit
Search Trop Picture
 
Synonyms:
 amalaki fruit extract
actiponeamla (amalki) fruit GW (Symrise)
 diasperus emblica fruit extract
 dichelactina nodicaulis fruit extract
 emblica fruit extract
 emblica officinalis fruit extract
 extract of the fruit of phyllanthus emblica l., euphorbiaceae
indian gooseberry fruit extract
 phyllanthus mairei fruit extract
 

Articles:

PubMed:Ultrasound-assisted extraction of phenolic compounds from Phyllanthus emblica L. and evaluation of antioxidant activities.
PubMed:Anti-diabetic effects of the Indian indigenous fruit Emblica officinalis Gaertn: active constituents and modes of action.
PubMed:Bioactivities of alcohol based extracts of Phyllanthus emblica branches: antioxidation, antimelanogenesis and anti-inflammation.
PubMed:Composition and Biological Activities of Hydrolyzable Tannins of Fruits of Phyllanthus emblica.
PubMed:[Optimization of the extraction process of the effective components in fructus phyllanthi].
PubMed:Scientific evaluation of edible fruits and spices used for the treatment of peptic ulcer in traditional Iranian medicine.
PubMed:Hepatoprotective properties of the Indian gooseberry (Emblica officinalis Gaertn): a review.
PubMed:Immunomodulatory role of Emblica officinalis in arsenic induced oxidative damage and apoptosis in thymocytes of mice.
PubMed:Pro-oxidant/antioxidant behaviours of ascorbic acid, tocopherol, and plant extracts in n-3 highly unsaturated fatty acid rich oil-in-water emulsions.
PubMed:Amla (Emblica officinalis Gaertn.) extract inhibits lipopolysaccharide-induced procoagulant and pro-inflammatory factors in cultured vascular endothelial cells.
PubMed:A novel phenolic compound from Phyllanthus emblica.
PubMed:Protective effect of Phyllanthus emblica fruit extract against hydrogen peroxide-induced endothelial cell death.
PubMed:Anticancer activity of Phyllanthus emblica Linn. (Indian gooseberry): inhibition of transcription factor AP-1 and HPV gene expression in cervical cancer cells.
PubMed:Instrumental neutron activation analysis of Emblica officinalis, Terminalia belerica and Terminalia chebula for trace element efficacy and safety.
PubMed:Phyllanthus emblica L. Enhances Human Umbilical Vein Endothelial Wound Healing and Sprouting.
PubMed:Nutrients and bioactive compounds of Thai indigenous fruits.
PubMed:Note on the relevance of Emblica officinalis Gaertn. for the treatment and prevention of cancer.
PubMed:Simultaneous determination and characterization of tannins and triterpene saponins from the fruits of various species of Terminalia and Phyllantus emblica using a UHPLC-UV-MS method: application to triphala.
PubMed:Chemopreventive efficacy of Phyllanthus emblica L. (amla) fruit extract on 7,12-dimethylbenz(a)anthracene induced oral carcinogenesis--a dose-response study.
PubMed:Studies on effects of Emblica officinalis (Amla) on oxidative stress and cholinergic function in scopolamine induced amnesia in mice.
PubMed:Antioxidant and antibacterial activities of vegetables and fruits commonly consumed in Thailand.
PubMed:Studies on prokinetic, laxative and spasmodic activities of Phyllanthus emblica in experimental animals.
PubMed:Analysis of hydrolyzable tannins and other phenolic compounds in emblic leafflower (Phyllanthus emblica L.) fruits by high performance liquid chromatography-electrospray ionization mass spectrometry.
PubMed:Antidiabetic and antioxidant potential of Emblica officinalis Gaertn. leaves extract in streptozotocin-induced type-2 diabetes mellitus (T2DM) rats.
PubMed:Efficacy of E. officinalis on the cariogenic properties of Streptococcus mutans: a novel and alternative approach to suppress quorum-sensing mechanism.
PubMed:Evaluation of 15 Local Plant Species as Larvicidal Agents Against an Indian Strain of Dengue Fever Mosquito, Aedes aegypti L. (Diptera: Culicidae).
PubMed:The isolation and characterization of β-glucogallin as a novel aldose reductase inhibitor from Emblica officinalis.
PubMed:Ergonomic evaluation of conventional and improved methods of aonla pricking with women workers.
PubMed:Ergonomic intervention in aonla pricking operation during preserve preparation in food processing industries.
PubMed:Influence of Emblica officinalis aqueous extract on growth and antioxidant defense system of human hepatoma cell line (HepG2).
PubMed:Possible involvement of monoaminergic neurotransmission in antidepressant-like activity of Emblica officinalis fruits in mice.
PubMed:Comparative study of antimicrobial activity and phytochemical analysis of methanolic and aqueous extracts of the fruit of Emblica officinalis against pathogenic bacteria.
PubMed:Hydroalcoholic extract of Emblica officinalis protects against kainic acid-induced status epilepticus in rats: evidence for an antioxidant, anti-inflammatory, and neuroprotective intervention.
PubMed:Effect of Amla fruit (Emblica officinalis Gaertn.) on blood glucose and lipid profile of normal subjects and type 2 diabetic patients.
PubMed:Quantification of gallic acidin fruits of three medicinal plants.
PubMed:Inhibition of UV-induced ROS and collagen damage by Phyllanthus emblica extract in normal human dermal fibroblasts.
PubMed:Amla (Emblica officinalis Gaertn), a wonder berry in the treatment and prevention of cancer.
PubMed:Extensive screening for herbal extracts with potent antioxidant properties.
PubMed:In vitro and in vivo antiplasmodial activity and cytotoxicity of water extracts of Phyllanthus emblica, Terminalia chebula, and Terminalia bellerica.
PubMed:Emblica officinalis ameliorates alcohol-induced brain mitochondrial dysfunction in rats.
PubMed:Antiinflammatory activity of Phyllanthus emblica, Plumbago zeylanica and Cyperus rotundus in acute models of inflammation.
PubMed:The antidiarrheal and spasmolytic activities of Phyllanthus emblica are mediated through dual blockade of muscarinic receptors and Ca2+ channels.
PubMed:Amelioration of alcohol-induced oxidative stress by Emblica officinalis (amla) in rats.
PubMed:Application of immobilized tannase from Aspergillus niger for the removal of tannin from myrobalan juice.
PubMed:Antitumour effects of Phyllanthus emblica L.: induction of cancer cell apoptosis and inhibition of in vivo tumour promotion and in vitro invasion of human cancer cells.
PubMed:Effect of Emblica officinalis (fruit) against UVB-induced photo-aging in human skin fibroblasts.
PubMed:Therapeutic potential of Phyllanthus emblica (amla): the ayurvedic wonder.
PubMed:Comparative study of the antioxidant and reactive oxygen species scavenging properties in the extracts of the fruits of Terminalia chebula, Terminalia belerica and Emblica officinalis.
PubMed:Ameliorative effect of Emblica officinalis aqueous extract on ochratoxin-induced lipid peroxidation in the kidney and liver of mice.
PubMed:Determination of gallic acid in Phyllanthus emblica Linn. dried fruit powder by HPTLC.
PubMed:Antioxidant activity and polyphenol content in edible wild fruits from Nepal.
PubMed:Antinociceptive property of Emblica officinalis Gaertn (Amla) in high fat diet-fed/low dose streptozotocin induced diabetic neuropathy in rats.
PubMed:Antimicrobial and cytotoxic activity of the alkaloids of Amlaki (Emblica officinalis).
PubMed:The protective role of amla (Emblica officinalis Gaertn.) against fructose-induced metabolic syndrome in a rat model.
PubMed:Characterization And Application Of Tannase Produced By Aspergillus Niger ITCC 6514.07 On Pomegranate Rind.
PubMed:Type I pro-collagen promoting and anti-collagenase activities of Phyllanthus emblica extract in mouse fibroblasts.
PubMed:Identification of volatile components in Phyllanthus emblica L. and their antimicrobial activity.
PubMed:Emblica officinalis protects against alcohol-induced liver mitochondrial dysfunction in rats.
PubMed:Modulatory role of Emblica officinalis fruit extract against arsenic induced oxidative stress in Swiss albino mice.
PubMed:Supplementation of Emblica officinalis (Amla) extract reduces oxidative stress in uremic patients.
PubMed:Chemical and antioxidant evaluation of Indian gooseberry (Emblica officinalis Gaertn., syn. Phyllanthus emblica L.) supplements.
PubMed:Ascorbic acid and tannins from Emblica officinalis Gaertn. Fruits--a revisit.
PubMed:Protective efficacy of Emblica officinalis against Klebsiella pneumoniae induced pneumonia in mice.
PubMed:Chondroprotective Potential of Fruit Extracts of Phyllanthus emblica in Osteoarthritis.
PubMed:Emblica officinalis and hepatocarcinogenesis: a chemopreventive study in Wistar rats.
PubMed:Antibacterial activity of some medicinal plant extracts.
PubMed:Extensive screening for edible herbal extracts with potent scavenging activity against superoxide anions.
PubMed:Reversal of hepatotoxin-induced pre-fibrogenic events by Emblica officinalis--a histological study.
PubMed:Modulating effect of Phyllanthus fruit extract against lead genotoxicity in germ cells of mice.
PubMed:An ethnomedicinal survey and documentation of important medicinal folklore food phytonims of flora of Samahni valley, (Azad Kashmir) Pakistan.
PubMed:Differential growth inhibitory effects of W. somnifera root and E. officinalis fruits on CHO cells.
PubMed:Alteration of DMBA-induced oxidative stress by additive action of a modified indigenous preparation--Kalpaamruthaa.
PubMed:Emblica officinalis (Linn.) fruit extract provides protection against radiation-induced hematological and biochemical alterations in mice.
PubMed:Analgesic, antipyretic and Ulcerogenic properties of an indigenous formulation--Kalpaamruthaa.
PubMed:Restorative effect of Kalpaamruthaa, an indigenous preparation, on oxidative damage in mammary gland mitochondrial fraction in experimental mammary carcinoma.
PubMed:Protection against radiation oxidative damage in mice by Triphala.
PubMed:The protective effects of Phyllanthus emblica Linn. extract on ethanol induced rat hepatic injury.
PubMed:Nitric oxide radical scavenging active components from Phyllanthus emblica L.
PubMed:Chemopreventive potential of Triphala (a composite Indian drug) on benzo(a)pyrene induced forestomach tumorigenesis in murine tumor model system.
PubMed:Biosynthesis of gold and silver nanoparticles using Emblica Officinalis fruit extract, their phase transfer and transmetallation in an organic solution.
PubMed:Vitamin C content and antioxidant activity of the fruit and of the Ayurvedic preparation of Emblica officinalis Gaertn.
PubMed:Radioprotection of Swiss albino mice by Emblica officinalis.
PubMed:Chemopreventive action of emblica officinalis on skin carcinogenesis in mice.
PubMed:Phenolic contents and antioxidant activity of some food and medicinal plants.
PubMed:Reversal of fibrogenic events in liver by Emblica officinalis (fruit), an Indian natural drug.
PubMed:Protective effect of a 50% hydroalcoholic fruit extract of Emblica officinalis against anti-tuberculosis drugs induced liver toxicity.
PubMed:The in vitro cytotoxic and apoptotic activity of Triphala--an Indian herbal drug.
PubMed:Modulation of haematopoetic system and antioxidant enzymes by Emblica officinalis gaertn and its protective role against gamma-radiation induced damages in mice.
PubMed:Protective effect of Emblica officinalis ethanolic extract against 7,12-dimethylbenz(a) anthracene (DMBA) induced genotoxicity in Swiss albino mice.
PubMed:[Studies on chemical constituents in fruits of Tibetan medicine Phyllanthus emblica].
PubMed:Emblica officinalis reverses thioacetamide-induced oxidative stress and early promotional events of primary hepatocarcinogenesis.
PubMed:Evaluation of anti-pyretic and analgesic activity of Emblica officinalis Gaertn.
PubMed:Antiproliferative activity of the main constituents from Phyllanthus emblica.
PubMed:Emblica officinalis causes myocardial adaptation and protects against oxidative stress in ischemic-reperfusion injury in rats.
PubMed:Immunomodulatory effects of agents of plant origin.
PubMed:Antitussive activity of the fruit extract of Emblica officinalis Gaertn. (Euphorbiaceae).
PubMed:Modulation of acute cadmium toxicity by Emblica officinalis fruit in rat.
PubMed:Indian medicinal plants as a reservoir of protective phytochemicals.
PubMed:Gastroprotective effects of 'Amla' Emblica officinalis on in vivo test models in rats.
PubMed:Emblica cascading antioxidant: a novel natural skin care ingredient.
PubMed:Anti-diabetic activity of medicinal plants and its relationship with their antioxidant property.
PubMed:Cyto-protective and immunomodulating properties of Amla (Emblica officinalis) on lymphocytes: an in-vitro study.
PubMed:Phyllanemblinins A-F, new ellagitannins from Phyllanthus emblica.
PubMed:New phenolic constituents from the fruit juice of Phyllanthus emblica.
PubMed:The role of antioxidant activity of Phyllanthus emblica fruits on prevention from indomethacin induced gastric ulcer.
PubMed:Inhibitory effects of Egyptian folk medicines on human immunodeficiency virus (HIV) reverse transcriptase.
PubMed:Relative efficiency of Phyllanthus emblica fruit extract and ascorbic acid in modifying lead and aluminium-induced sister-chromatid exchanges in mouse bone marrow.
PubMed:Relative protection given by extract of Phyllanthus emblica fruit and an equivalent amount of vitamin C against a known clastogen--caesium chloride.
PubMed:Modification of metal-induced micronuclei formation in mouse bone marrow erythrocytes by Phyllanthus fruit extract and ascorbic acid.
PubMed:Modifying role of Phyllanthus emblica and ascorbic acid against nickel clastogenicity in mice.
PubMed:Modification of clastogenicity of lead and aluminium in mouse bone marrow cells by dietary ingestion of Phyllanthus emblica fruit extract.
PubMed:[Inhibitory effects of Phyllanthus emblica juice on formation of N-nitrosomorpholine in vitro and N-nitrosoproline in rat and human].
 
Notes:
Derived from the Emblica officinalis fruit, Emblica officinalis fruit extract is measured as no more than 20% phenols derivatives typically gallic acid and gallic acid esters; 7% Lactones typically mucic acid lactone and ascorbate; 3% Aliphatic carboxylic acids with additional oxygenated functional groups; 60% Carbohydrates and no more than 5% ash
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