Articles: PubMed:Memory-Enhancing Effects of the Crude Extract of Polygala tenuifolia on Aged Mice. PubMed:Protective effect of senegenin on splenectomy-induced postoperative cognitive dysfunction in elderly rats. PubMed:The discovery of Yuanzhi-1, a triterpenoid saponin derived from the traditional Chinese medicine, has antidepressant-like activity. PubMed:Preclinical evidence of rapid-onset antidepressant-like effect in Radix Polygalae extract. PubMed:Neuroprotective Effects of 3,6'-Disinapoyl Sucrose Through Increased BDNF Levels and CREB Phosphorylation via the CaMKII and ERK1/2 Pathway. PubMed:High throughput screening of natural products for anti-mitotic effects in MDA-MB-231 human breast carcinoma cells. PubMed:The inhibition of JNK MAPK and NF-κB signaling by tenuifoliside A isolated from Polygala tenuifolia in lipopolysaccharide-induced macrophages is associated with its anti-inflammatory effect. PubMed:Analysis and detection of the chemical constituents of Radix Polygalae and their metabolites in rats after oral administration by ultra high-performance liquid chromatography coupled with electrospray ionization quadrupole time-of-flight tandem mass spectrometry. PubMed:Tenuigenin ameliorates learning and memory impairments induced by ovariectomy. PubMed:Tenuigenin treatment improves behavioral Y-maze learning by enhancing synaptic plasticity in mice. PubMed:Senegenin attenuates hepatic ischemia-reperfusion induced cognitive dysfunction by increasing hippocampal NR2B expression in rats. PubMed:Anti-inflammatory effects of Polygala tenuifolia root through inhibition of NF-κB activation in lipopolysaccharide-induced BV2 microglial cells. PubMed:Effects of the crude extract of Polygala tenuifolia Willd on human sperm in vitro. PubMed:Neuroprotective effects of tenuigenin in a SH-SY5Y cell model with 6-OHDA-induced injury. PubMed:Polygalae radix inhibits toxin-induced neuronal death in the Parkinson's disease models. PubMed:Antioxidant activity of oligosaccharide ester extracted from Polygala tenuifolia roots in senescence-accelerated mice. PubMed:Anxiolytic and sedative-hypnotic activities of polygalasaponins from Polygala tenuifolia in mice. PubMed:Antidepressant effects of the extract YZ-50 from Polygala tenuifolia in chronic mild stress treated rats and its possible mechanisms. PubMed:Polygalasaponin XXXII from Polygala tenuifolia root improves hippocampal-dependent learning and memory. PubMed:Localization and dynamic change of saponin in vegetative organs of Polygala tenuifolia. PubMed:BT-11 improves stress-induced memory impairments through increment of glucose utilization and total neural cell adhesion molecule levels in rat brains. PubMed:Effects of Polygala tenuifolia root extract on proliferation of neural stem cells in the hippocampal CA1 region. PubMed:Effect of Polygala tenuifolia root extract on scopolamine-induced impairment of rat spatial cognition in an eight-arm radial maze task. PubMed:Cerebral protective and cognition-improving effects of sinapic acid in rodents. PubMed:Effect of Polygala tenuifolia root extract on cerebral ischemia and reperfusion. PubMed:[Studies on the chemical constituents in root bark of Polygala tenuifolia (II)]. PubMed:Attenuation of cocaine-induced conditioned place preference by Polygala tenuifolia root extract. PubMed:Effect of Polygala tenuifolia root on behavioral disorders by lesioning nucleus basalis magnocellularis in rat. PubMed:Tenuifoliose Q, a new oligosaccharide ester from the root of Polygala tenuifolia Willd. PubMed:Induction of NGF synthesis in astrocytes by onjisaponins of Polygala tenuifolia, constituents of kampo (Japanese herbal) medicine, Ninjin-yoei-to. PubMed:[Studies on chemical constituents of fat oil of Polygala tenuifolia]. PubMed:Novel cognitive improving and neuroprotective activities of Polygala tenuifolia Willdenow extract, BT-11. PubMed:Onjisaponins, from the root of Polygala tenuifolia Willdenow, as effective adjuvants for nasal influenza and diphtheria-pertussis-tetanus vaccines. PubMed:Effect of Polygala tenuifolia root extract on the tumor necrosis factor-alpha secretion from mouse astrocytes. PubMed:[SUGAR COMPONENTS OF THE ROOT OF POLYGALA TENUIFOLIA].