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panax notoginseng extract
extract of the ginseng, panax notoginseng, araliaceae

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Name:panax notoginseng extract
CAS Number: 94279-78-4
ECHA EC Number:304-823-9
FDA UNII: Search
Category:cosmetic and flavor agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Physical Properties:
Food Chemicals Codex Listed: No
Organoleptic Properties:
Flavor Type: earthy
Taste Description: ginseng
Odor and/or flavor descriptions from others (if found).
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: skin conditioning
BOC Sciences
For experimental / research use only.
Panax Notoginseng Extract 80%; 10:1
Changsha Organic Herb
Notoginseng Extract
Chemical-navi - Nikkol
Dongguan Meiherb Biotech
Radix Notoginseng extract
Odor: characteristic
Use: Radix Notoginseng extract has advance effects on anti-tumor, anti-inflammation, antioxidation/anti-aging, nervous system, immune system, blood and hematopoietic system. It also enhances the body's resistance to radiation ability and reduce radiation to hematopoietic system damage.
Ginseng Extract
NAT arom®, liquid or powder forms
Ginseng Extract
Ginseng SDE
Safety Information:
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Safety in Use Information:
cosmetic and flavor agents
Recommendation for panax notoginseng extract usage levels up to:
 not for fragrance use.
Safety References:
European Food Safety Authority (EFSA) reference(s):

Safety of a botanical extract derived from Panax notoginseng and Astragalus membranaceus (AstraGinÖ) as a novel food pursuant to Regulation (EU) 2015/2283
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AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
National Institute of Allergy and Infectious Diseases:Data
panax notoginseng extract
 panax notoginseng extract
Pubchem (sid):135324403
Other Information:
Potential Blenders and core components note
For Odor
For Flavor
ginseng essence
ginseng flavor
panax quinquefolius root extract
ginseng distillates
panax ginseng root extract
Potential Uses:
None Found
Occurrence (nature, food, other):note
 panax notoginseng
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 extract of the ginseng, panax notoginseng, araliaceae
 ginseng extract china/japan
 ginseng extract powder M
 notoginseng extract


PubMed:[Chemical constituents from processed rhizomes of Panax notoginseng].
PubMed:[Sample pretreatment methods of pesticide residues in Panax notoginseng of Chinese traditional medicine].
PubMed:Bioactive protopanaxatriol type saponins isolated from the roots of Panax notoginseng (Burk.) F. H. Chen.
PubMed:A novel strategy with standardized reference extract qualification and single compound quantitative evaluation for quality control of Panax notoginseng used as a functional food.
PubMed:A comparative study on anticoagulant activities of three Chinese herbal medicines from the genus Panax and anticoagulant activities of ginsenosides Rg1 and Rg2.
PubMed:Antioxidant, antiproliferative, and pro-apoptotic activities of a saponin extract derived from the roots of Panax notoginseng (Burk.) F.H. Chen.
PubMed:[Study on the dynamic model with supercritical CO2 fluid extracting the lipophilic components in Panax notoginseng].
PubMed:Combination of total astragalus extract and total Panax notoginseng saponins strengthened the protective effects on brain damage through improving energy metabolism and inhibiting apoptosis after cerebral ischemia-reperfusion in mice.
PubMed:An integrated high resolution mass spectrometric data acquisition method for rapid screening of saponins in Panax notoginseng (Sanqi).
PubMed:Optimization of the ethanol recycling reflux extraction process for saponins using a design space approach.
PubMed:[Major hypoglycemic ingredients of panax notoginseng saponins for treating diabetes].
PubMed:[Chemical constituents from processed rhizomes of Panax notoginseng].
PubMed:[Sample pretreatment methods of pesticide residues in Panax notoginseng of Chinese traditional medicine].
PubMed:Panax notoginseng attenuates experimental colitis in the azoxymethane/dextran sulfate sodium mouse model.
PubMed:A comparative study on anticoagulant activities of three Chinese herbal medicines from the genus Panax and anticoagulant activities of ginsenosides Rg1 and Rg2.
PubMed:Effects of Borneol on Pharmacokinetics and Tissue Distribution of Notoginsenoside R1 and Ginsenosides Rg1 and Re in Panax notoginseng in Rabbits.
PubMed:An Aqueous Extract of Radix Astragali, Angelica sinensis, and Panax notoginseng Is Effective in Preventing Diabetic Retinopathy.
PubMed:Combinatorial metabolism notably affects human systemic exposure to ginsenosides from orally administered extract of Panax notoginseng roots (Sanqi).
PubMed:[HPLC fingerprint of compound xueshuantong capsule].
PubMed:Hormesis-based anti-aging products: a case study of a novel cosmetic.
PubMed:Antagonism of Cortex Periplocae extract-induced catecholamines secretion by Panax notoginseng saponins in cultured bovine adrenal medullary cells by drug combinations.
PubMed:Panax notoginseng saponins induced up-regulation, phosphorylation and binding activity of MEK, ERK, AKT, PI-3K protein kinases and GATA transcription factors in hematopoietic cells.
PubMed:Evaluation of the anti-myocardial ischemia effect of individual and combined extracts of Panax notoginseng and Carthamus tinctorius in rats.
PubMed:Enhanced separation of Compound Xueshuantong capsule using functionalized carbon nanotubes with cationic surfactant solutions in MEEKC.
PubMed:[Protection effect and mechanism of Compound Xueshuantong Capsule on diabetic nephropathy rats].
PubMed:The effects of a novel botanical agent on lipopolysaccharide-induced alveolar bone loss in rats.
PubMed:Improvement of hematoma absorption and neurological function in patients with acute intracerebral hemorrhage treated with Xueshuantong.
PubMed:[Study on optimization method of dynamic extraction process].
PubMed:More accurate matrix-matched quantification using standard superposition method for herbal medicines.
PubMed:[Effect of notoginseng extracts and their components on lipopolysaccharide and galactosamine mixture-induced impaired hepatic function in mice].
PubMed:Sesquiterpenes and cyclopeptides from the endophytic fungus Trichoderma asperellum SAMUELS, LIECKF. & NIRENBERG.
PubMed:Effects of Panax notoginseng (Chinese ginseng) and acute exercise on postprandial glycemia in non-diabetic adults.
PubMed:Effects of Panax notoginseng flower extract on the TGF-╬▓/Smad signal transduction pathway in heart remodeling of human chymase transgenic mice.
PubMed:Analysis of Panax notoginseng metabolites in rat bile by liquid chromatography-quadrupole time-of-flight mass spectrometry with microdialysis sampling.
PubMed:Interstitial granulomatous drug reaction to a Chinese herb extract.
PubMed:Antioxidant, antiproliferative, and pro-apoptotic activities of a saponin extract derived from the roots of Panax notoginseng (Burk.) F.H. Chen.
PubMed:Panax notoginseng and its components decreased hypertension via stimulation of endothelial-dependent vessel dilatation.
PubMed:[Study on the dynamic model with supercritical CO2 fluid extracting the lipophilic components in Panax notoginseng].
PubMed:Inhibition of TLR ligand- and interferon gamma-induced murine microglial activation by Panax notoginseng.
PubMed:Panax notoginsenoside produces neuroprotective effects in rat model of acute spinal cord ischemia-reperfusion injury.
PubMed:Protective effects of Ligustrazine, Kakonein and Panax Notoginsenoside on the small intestine and immune organs of rats with severe acute pancreatitis.
PubMed:Target separation of a new anti-tumor saponin and metabolic profiling of leaves of Panax notoginseng by liquid chromatography with eletrospray ionization quadrupole time-of-flight mass spectrometry.
PubMed:Induction of differentiation by panaxydol in human hepatocarcinoma SMMC-7721 cells via cAMP and MAP kinase dependent mechanism.
PubMed:Effects of Panax notoginoside on the expression of TGF-╬▓1 and Smad-7 in renal tissues of diabetic rats.
PubMed:Panax notoginseng Attenuates Bleomycin-Induced Pulmonary Fibrosis in Mice.
PubMed:Isolation of four high-purity dammarane saponins from extract of Panax notoginseng by centrifugal partition chromatography coupled with evaporative light scattering detection in one operation.
PubMed:[Effect of total saponins of Panax notoginseng on urinary albumin in patients with chronic renal failure].
PubMed:Anti-oxidative effects of the biennial flower of Panax notoginseng against H2O2-induced cytotoxicity in cultured PC12 cells.
PubMed:Protective effect of panaxatriol saponins extracted from Panax notoginseng against MPTP-induced neurotoxicity in vivo.
PubMed:Amelioration of radiation-induced hematological and biochemical alterations in Swiss albino mice by Panax ginseng extract.
PubMed:[Effect of intracoronary injection with xuesaitong in treating post-PCI slow-reflow phenomenon in patients with ST-segment elevation myocardial infarction].
PubMed:The influence of Sam-Chil-Geun (Panax notoginseng) on the serum lipid levels and inflammations of rats with hyperlipidemia induced by poloxamer-407.
PubMed:Effects of AIF on Knee Osteoarthritis Patients: Double-blind, Randomized Placebo-controlled Study.
PubMed:Inhibition of Arterial Myogenic Responses by a Mixed Aqueous Extract of Salvia Miltiorrhiza and Panax Notoginseng (PASEL) Showing Antihypertensive Effects.
PubMed:Absorption and disposition of ginsenosides after oral administration of Panax notoginseng extract to rats.
PubMed:Antiplatelet and anticoagulant effects of Panax notoginseng: comparison of raw and steamed Panax notoginseng with Panax ginseng and Panax quinquefolium.
PubMed:[HPLC-CAD in optimizating of saponins extraction from Radix et Rhizoma Notoginseng].
PubMed:Simultaneous determination of notoginsenoside R1, ginsenoside Rg1, Re, Rb1 and icariin in rat plasma by ultra-performance liquid chromatography-tandem mass spectrometry.
PubMed:Induction of apoptosis in human lung carcinoma cells by the water extract of Panax notoginseng is associated with the activation of caspase-3 through downregulation of Akt.
PubMed:Anticancer activity of Panax notoginseng extract 20(S)-25-OCH3-PPD: Targetting beta-catenin signalling.
PubMed:Panax notoginseng Attenuates the Infarct Volume in Rat Ischemic Brain and the Inflammatory Response of Microglia.
PubMed:Detection of adulteration of notoginseng root extract with other panax species by quantitative HPLC coupled with PCA.
PubMed:[Cloning and characterization of cDNA encoding Psammosilene tunicoides squalene synthase].
PubMed:Flower extract of Panax notoginseng attenuates lipopolysaccharide-induced inflammatory response via blocking of NF-kappaB signaling pathway in murine macrophages.
PubMed:Effects of cardiotonic pill on RBC rheologic abnormalities in HFD-induced mice and LPL deficient mice.
PubMed:Angiogenic effect of saponin extract from Panax notoginseng on HUVECs in vitro and zebrafish in vivo.
PubMed:Antiproliferative effects of different plant parts of Panax notoginseng on SW480 human colorectal cancer cells.
PubMed:A rapid ultra-performance liquid chromatography-electrospray Ionisation mass spectrometric method for the analysis of saponins in the adventitious roots of Panax notoginseng.
PubMed:[Formulation optimization of panax notoginsenoside orally fast disintegration tablets].
PubMed:Rapid and sensitive analysis of multiple bioactive constituents in Compound Danshen preparations using LC-ESI-TOF-MS.
PubMed:Ultrasound phonophoresis of panax notoginseng improves the strength of repairing ligament: a rat model.
PubMed:Effects of Radix notoginseng extracts drug-containing serum on expressions of bcl-2, Bax and p21WAF1 proteins in MNNG transformed GES-1 cells.
PubMed:Effects of extracts from Panax notoginseng and Panax ginseng fruit on vascular endothelial cell proliferation and migration in vitro.
PubMed:[Optimization for vacuum belt drying process of Panax notoginseng extract].
PubMed:Interaction of salvianolic acids and notoginsengnosides in inhibition of ADP-induced platelet aggregation.
PubMed:The effects of Panax ginseng and Spirulina platensis on hepatotoxicity induced by cadmium in rats.
PubMed:[Studies on chemical constituents from rhizomes of Panax notoginseng].
PubMed:Protective effect of saponins from Panax notoginseng against doxorubicin-induced cardiotoxicity in mice.
PubMed:[Experimental study of hematopoietic cell gene expression profile induced by panax notoginosides in vitro].
PubMed:Toll-like receptor ligand-induced activation of murine DC2.4 cells is attenuated by Panax notoginseng.
PubMed:Anti-inflammatory effects of BT-201, an n-butanol extract of Panax notoginseng, observed in vitro and in a collagen-induced arthritis model.
PubMed:Chemopreventive effects of Panax notoginseng and its major constituents on SW480 human colorectal cancer cells.
PubMed:Effects of four medicinal herbs on human vascular endothelial cells in culture.
PubMed:Hypolipidemic effects and mechanisms of Panax notoginseng on lipid profile in hyperlipidemic rats.
PubMed:[Experimental study on anti-platelet effects of ginsenoside -2A in vitro].
PubMed:Pharmacokinetic and absolute bioavailability study of total panax notoginsenoside, a typical multiple constituent traditional chinese medicine (TCM) in rats.
PubMed:Ultra-performance liquid chromatography/time-of-flight mass spectrometry based metabolomics of raw and steamed Panax notoginseng.
PubMed:Immunological-adjuvant saponins from the roots of Panax notoginseng.
PubMed:Inhibitory effect of Panax notoginseng on nitric oxide synthase, cyclo-oxygenase-2 and neutrophil functions.
PubMed:Simultaneous determination of seven active components of Fufang Danshen tablet by high performance liquid chromatography.
PubMed:Notoginseng enhances anti-cancer effect of 5-fluorouracil on human colorectal cancer cells.
PubMed:Attenuating effect of Myakuryu on mesenteric microcirculatory disorders induced by ischemia and reperfusion.
PubMed:Panax notoginseng attenuates LPS-induced pro-inflammatory mediators in RAW264.7 cells.
PubMed:Compound salvia pellet, a traditional Chinese medicine, for the treatment of chronic stable angina pectoris compared with nitrates: a meta-analysis.
PubMed:Orthogonal array design in optimizing the extraction efficiency of active constituents from roots of Panax notoginseng.
PubMed:A Korean herbal medicine, Panax notoginseng, prevents liver fibrosis and hepatic microvascular dysfunction in rats.
PubMed:Comparative study of the composition of TCM Radix notoginseng extract samples before and after acetylation with UV and ELSD detection.
PubMed:The antioxidant effects of aqueous and organic extracts of Panax quinquefolium, Panax notoginseng, Codonopsis pilosula, Pseudostellaria heterophylla and Glehnia littoralis.
PubMed:[Identification of Panax notoginseng and its preparations by LC/MS].
PubMed:Interactions of a herbal combination that inhibits growth of prostate cancer cells.
PubMed:Protection by hot water extract of Panax notoginseng on chronic ethanol-induced hepatotoxicity.
PubMed:Isolation of dammarane saponins from Panax notoginseng by high-speed counter-current chromatography.
PubMed:Pananotin, a potent antifungal protein from roots of the traditional chinese medicinal herb Panax notoginseng.
PubMed:Sensitization of a tumor, but not normal tissue, to the cytotoxic effect of ionizing radiation using Panax notoginseng extract.
PubMed:Effects of Ginsenoside Rb2 and Rc on inferior human sperm motility in vitro.
PubMed:Orally administered Panax notoginseng influence on rat spontaneous behaviour.
PubMed:Anti-carcinogenic activity of the roots of Panax notoginseng. II.
PubMed:Effect of panax notoginseng extracts on inferior sperm motility in vitro.
PubMed:Hepatoprotective effects of Panax notoginseng: Ginsenosides -Re and -Rg(1) as its active constituents in D-galactosamine/lipopolysaccharide-induced liver injury.
PubMed:[Effects of artificial cultured Panax notoginseng cell on cardiovascular system].
None found
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