| Name: | euphorbia peplus l. extract |
| CAS Number: | 90028-62-9 |
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| ECHA EC Number: | 289-855-0 |
| FDA UNII: | Search |
Category:information only not used for fragrances or flavors
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Food Chemicals Codex Listed: | No |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | information only not used for fragrances or flavors |
| Recommendation for euphorbia peplus extract usage levels up to: | | | not for fragrance use.
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| Recommendation for euphorbia peplus extract flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
| | euphorbia peplus l. extract |
| Pubchem (sid): | 135282331 |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
Articles:
| PubMed:The European Medicines Agency approval of ingenol mebutate (Picato) for the cutaneous treatment of non-hyperkeratotic, non-hypertrophic actinic keratosis in adults: Summary of the scientific assessment of the Committee for Medicinal Products for Human Use (CHMP). |
| PubMed:The value of nature's natural product library for the discovery of New Chemical Entities: The discovery of ingenol mebutate. |
| PubMed:Euphorbia peplus: 18th-century insights on a 21st-century therapy. |
| PubMed:Ingenol mebutate: A novel topical drug for actinic keratosis. |
| PubMed:14-step synthesis of (+)-ingenol from (+)-3-carene. |
| PubMed:Long-term follow-up study of ingenol mebutate gel for the treatment of actinic keratoses. |
| PubMed:Ingenol mebutate: a new option for actinic keratosis treatment. |
| PubMed:Ingenol mebutate gel 0.015% and 0.05%: in actinic keratosis. |
| PubMed:Ingenol mebutate: potential for further development of cancer immunotherapy. |
| PubMed:Ingenol mebutate: an introduction. |
| PubMed:The sap from Euphorbia peplus is effective against human nonmelanoma skin cancers. |
| PubMed:Which plant for which skin disease? Part 2: Dermatophytes, chronic venous insufficiency, photoprotection, actinic keratoses, vitiligo, hair loss, cosmetic indications. |
| PubMed:The skin cancer chemotherapeutic agent ingenol-3-angelate (PEP005) is a substrate for the epidermal multidrug transporter (ABCB1) and targets tumor vasculature. |
| PubMed:Floristic composition and vegetation analysis in Hail region north of central Saudi Arabia. |
| PubMed:The protein kinase C agonist PEP005 (ingenol 3-angelate) in the treatment of human cancer: a balance between efficacy and toxicity. |
| PubMed:Randomized, double-blind, double-dummy, vehicle-controlled study of ingenol mebutate gel 0.025% and 0.05% for actinic keratosis. |
| PubMed:PEP005 (ingenol mebutate) gel, a novel agent for the treatment of actinic keratosis: results of a randomized, double-blind, vehicle-controlled, multicentre, phase IIa study. |
| PubMed:Effects of protein kinase C modulation by PEP005, a novel ingenol angelate, on mitogen-activated protein kinase and phosphatidylinositol 3-kinase signaling in cancer cells. |
| PubMed:Wild vascular plants gathered for consumption in the Polish countryside: a review. |
| PubMed:Proceedings of the First International Conference on PEP005. |
| PubMed:Discovery and biological evaluation of the novel naturally occurring diterpene pepluanone as antiinflammatory agent. |
| PubMed:PEP005, a selective small-molecule activator of protein kinase C, has potent antileukemic activity mediated via the delta isoform of PKC. |
| PubMed:Ingenol 3-angelate induces dual modes of cell death and differentially regulates tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in melanoma cells. |
| PubMed:Characterization of the interaction of ingenol 3-angelate with protein kinase C. |
| PubMed:Antitumor activity of 3-ingenyl angelate: plasma membrane and mitochondrial disruption and necrotic cell death. |
| PubMed:Jatrophane diterpenes as modulators of multidrug resistance. Advances of structure-activity relationships and discovery of the potent lead pepluanin A. |
| PubMed:Effect of Ruta graveolens L. and Euphorbia peplus L. anti-inflammatory extracts on nutritional status of rats and the safety of their use. |
| PubMed:Diterpenoids from Euphorbia peplus. |
| PubMed:Nonpolar components of the latex of Euphorbia peplus. |
| PubMed:Jatrophane diterpenoids from Euphorbia peplus. |
| PubMed:Isolation and structure revision of pepluane diterpenoids from euphorbia peplus |
| PubMed:Dietary cancer risk from conditional cancerogens in produce of livestock fed on species of spurge (Euphorbiaceae). III. Milk of lactating goats fed on the skin irritant herb Euphorbia peplus is polluted by tumor promoters of the ingenane diterpene ester type. |
| PubMed:Dietary cancer risk from conditional cancerogens in produce of livestock fed on species of spurge (Euphorbiaceae). II. Pathophysiological investigations in lactating goats fed on the skin irritant herb Euphorbia peplus and in their milk-raised kids. |
| PubMed:Acute kerato-uveitis associated with topical self-administration of the sap of the Petty Spurge (Euphorbia peplus) |
| PubMed:A soap technique for cell separation to study the seed coat of Sesbania punicea. |
| PubMed:Euphorbia peplus latex keratoconjunctivitis. |
| PubMed:Home treatment of basal cell carcinoma. |
| PubMed:Phytochemical study of Euphorbia peplus. |
| PubMed:Petty spurge (Euphorbia peplus L.). |
| PubMed:[Isolation and identification of flavonol glycosides from Euphorbia exigua and Euphorbia peplus. 7. Flavonoids indigenous to Euphorbia]. |
| PubMed:[Pharmacognostic studies on Euphorbia peplus L]. |
| PubMed:A pharmacological study of the Egyptian plant, Euphorbia peplus. |
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