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celastrus paniculatus leaf/flower/seed extract
extract of the seeds, leaves and flowers of celastrus paniculata, celastraceae

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CAS Number:	93333-86-9
ECHA EC Number:	297-056-3
FDA UNII:	Search

Category:cosmetic ingredient for skin conditioning

US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:

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Physical Properties:

Food Chemicals Codex Listed:

No

Organoleptic Properties:

Odor and/or flavor descriptions from others (if found).

Cosmetic Information:

CosIng:	cosmetic data
Cosmetic Uses:	skin conditioning

Suppliers:

None found

Safety Information:


Hazards identification

Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements

Pictogram

Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intraperitoneal-mouse LD50 500 mg/kg Indian Journal of Experimental Biology. Vol. 7, Pg. 250, 1969. oral-rat LD > 5000 mg/kg Journal of Ethnopharmacology. Vol. 47, Pg. 101, 1995.
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in Use Information:

Category:
cosmetic ingredient for skin conditioning
Recommendation for celastrus paniculatus leaf/flower/seed extract usage levels up to:
	not for fragrance use.

Recommendation for celastrus paniculatus leaf/flower/seed extract flavor usage levels up to:
	not for flavor use.

Safety References:

AIDS Citations:Search

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EPA ACToR:Toxicology Data

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National Institute of Allergy and Infectious Diseases:Data

celastrus paniculata leaf/flower/seed extract

Chemidplus:0093333869

References:

	celastrus paniculata leaf/flower/seed extract
Pubchem (sid):	135318193

Other Information:

Wikipedia:

Potential Blenders and core components note

None Found

Potential Uses:

None Found

Occurrence (nature, food, other):note

celastrus paniculata
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Synonyms:

	celastrus dependens leaf/flower/seed extract
	celastrus euphlebiphyllus leaf/flower/seed extract
	celastrus leaf/flower/seed extract
	celastrus multiflorus leaf/flower/seed extract
	celastrus paniculatus subsp. multiflorus leaf/flower/seed extract
	celastrus paniculatus subsp. serratus leaf/flower/seed extract
	celastrus paniculatus willd. extract excluding roots
	diosma serrata leaf/flower/seed extract
	euonymus euphlebiphyllus leaf/flower/seed extract
	extract of the seeds, leaves and flowers of celastrus paniculata, celastraceae
	malkangni leaf/flower/seed extract

Articles:

PubMed:Facile access to optically active ring C aromatic diterpene derivatives from (+)-manool. first synthesis of 13,14-dihydroxy8,11,13-podocarpatrien-7-one.

PubMed:Cytotoxic constituents from Celastrus paniculatus induce apoptosis and autophagy in breast cancer cells.

PubMed:In-vitro activity of saponins of bauhinia purpurea, madhuca longifolia, celastrus paniculatus and semecarpus anacardium on selected oral pathogens.

PubMed:Cortico-hippocampal salvage in chronic aluminium induced neurodegeneration by Celastrus paniculatus seed oil: Neurobehavioural, biochemical, histological study.

PubMed:Hypolipidemic Effect of Celastrus paniculatus in Experimentally Induced Hypercholesterolemic Wistar Rats.

PubMed:The role of natural products in the discovery of new drug candidates for the treatment of neurodegenerative disorders II: Alzheimer's disease.

PubMed:Nootropic activity of Celastrus paniculatus seed.

PubMed:Effect of Celastrus paniculatus seed oil (Jyothismati oil) on acute and chronic immobilization stress induced in swiss albino mice.

PubMed:Potent relaxant effect of a Celastrus paniculatus extract in the rat and human ileum.

PubMed:Wound healing activity and docking of glycogen-synthase-kinase-3-beta-protein with isolated triterpenoid lupeol in rats.

PubMed:Identification of a new sesquiterpene polyol ester from Celastrus paniculatus.

PubMed:Evaluation of anxiolytic potential of Celastrus oil in rat models of behaviour.

PubMed:Celastrus paniculatus seed oil and organic extracts attenuate hydrogen peroxide- and glutamate-induced injury in embryonic rat forebrain neuronal cells.

PubMed:New sesquiterpenes with intestinal relaxant effect from Celastrus paniculatus.

PubMed:Celastrus paniculatus seed water soluble extracts protect against glutamate toxicity in neuronal cultures from rat forebrain.

PubMed:Celastrus paniculatus seed water soluble extracts protect cultured rat forebrain neuronal cells from hydrogen peroxide-induced oxidative injury.

PubMed:Screening South Indian medicinal plants for antifungal activity against cutaneous pathogens.

PubMed:Antioxidant property of Celastrus paniculatus willd.: a possible mechanism in enhancing cognition.

PubMed:Rapid in vitro multiplication and restoration of Celastrus paniculatus Willd. sub sp. paniculatus (Celastraceae), a medicinal woody climber.

PubMed:Improved polygalacturonase production from Bacillus sp. MG-cp-2 under submerged (SmF) and solid state (SSF) fermentation.

PubMed:Indian medicinal plants as antiradicals and DNA cleavage protectors.

PubMed:Reversal of scopolamine-induced deficits in navigational memory performance by the seed oil of Celastrus paniculatus.

PubMed:Effects of Celastrus paniculatus on passive avoidance performance and biogenic amine turnover in albino rats.

PubMed:Preliminary screening of methanolic extracts of Celastrus paniculatus and Tecomella undulata for analgesic and anti-inflammatory activities.

PubMed:Antispermatogenic action of Celastrus paniculatus seed extract in the rat with reversible changes in the liver.

PubMed:Effect of Celastrus paniculatus seed extract on the brain of albino rats.

PubMed:BEHAVIOURAL AND PHARMACOLOGICAL STUDIES OF A TRANQUILISING FRACTION FROM THE OIL OF CELASTRUS PANICULATUS (MALKANGUNI OIL).

Notes:

extracted from seeds of celastrus paniculatus.

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