vitex rotundifolia leaf oil
volatile oil obtained from the leaves of vitex rotundifolia
None found
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Category: antioxidants
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Physical Properties:
Food Chemicals Codex Listed: No
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Organoleptic Properties:
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: antioxidants
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 None found
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Safety Information:
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: antioxidants
Recommendation for vitex rotundifolia leaf oil usage levels up to:
 not for fragrance use.
Recommendation for vitex rotundifolia leaf oil flavor usage levels up to:
 not for flavor use.
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Safety References:
None found
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None found
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Other Information:
Wikipedia: View
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Potential Blenders and core components note
None Found
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 vitex rotundifolia leaf
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roundleaf chaste tree leaf oil
roundleaf chastetree leaf oil
 vitex ovata leaf oil
 vitex ovata var. subtrisecta leaf oil
 vitex trifolia var. ovata leaf oil
 vitex trifolia var. simplicifolia leaf oil
 vitex trifolia var. unifoliolata leaf oil
 volatile oil obtained from the leaves of vitex rotundifolia
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PubMed: Determination and Identification of a Specific Marker Compound for Discriminating Shrub Chaste Tree Fruit from Agnus Castus Fruit Based on LC/MS Metabolic Analysis.
PubMed: Identification of New Diterpenes as Putative Marker Compounds Distinguishing Agnus Castus Fruit (Chaste Tree) from Shrub Chaste Tree Fruit (Viticis Fructus).
PubMed: Casticin, an active compound isolated from Vitex Fructus, ameliorates the cigarette smoke-induced acute lung inflammatory response in a murine model.
PubMed: 5,3'-Dihydroxy-6,7,4'-trimethoxyflavanone exerts its anticancer and antiangiogenesis effects through regulation of the Akt/mTOR signaling pathway in human lung cancer cells.
PubMed: Casticin inhibits COX-2 and iNOS expression via suppression of NF-κB and MAPK signaling in lipopolysaccharide-stimulated mouse macrophages.
PubMed: Activation of the apoptosis signal-regulating kinase 1/c-Jun N-terminal kinase pathway is involved in the casticin-induced apoptosis of colon cancer cells.
PubMed: Development of microsatellite markers for Vitex rotundifolia (Verbenaceae), an endangered coastal plant in Lake Biwa, Japan.
PubMed: Antiproliferative effect of flavonoids from the halophyte Vitex rotundifolia on human cancer cells.
PubMed: A synthetic compound, 4-acetyl-3-methyl-6-(3,4,5-trimethoxyphenyl)pyrano[3,4-c]pyran-1,8-dione, ameliorates ovalbumin-induced asthma.
PubMed: Anti-inflammatory constituents from the fruits of Vitex rotundifolia.
PubMed: Vitexicarpin acts as a novel angiogenesis inhibitor and its target network.
PubMed: A novel synthetic compound 4-acetyl-3-methyl-6-(2-bromophenyl)pyrano[3,4-c]pyran-1,8-dione inhibits the production of nitric oxide and proinflammatory cytokines via the NF-κB pathway in lipopolysaccharide-activated microglia cells.
PubMed: Vitex rotundifolia L. prevented airway eosinophilic inflammation and airway remodeling in an ovalbumin-induced asthma mouse model.
PubMed: Vitexicarpin induces apoptosis in human prostate carcinoma PC-3 cells through G2/M phase arrest.
PubMed: Vascular protective role of vitexicarpin isolated from Vitex rotundifolia in human umbilical vein endothelial cells.
PubMed: Inhibitory effects of casticin on migration of eosinophil and expression of chemokines and adhesion molecules in A549 lung epithelial cells via NF-κB inactivation.
PubMed: Casticin, a flavonoid isolated from Vitex rotundifolia, inhibits prolactin release in vivo and in vitro.
PubMed: A new compound, 1H,8H-pyrano[3,4-c]pyran-1,8-dione, suppresses airway epithelial cell inflammatory responses in a murine model of asthma.
PubMed: Inhibition effects of Vitex rotundifolia on inflammatory gene expression in A549 human epithelial cells.
PubMed: Casticin induces leukemic cell death through apoptosis and mitotic catastrophe.
PubMed: Beach dune sand hydrophobicity due to the presence of beach vitex ( Vitex rotundifolia L. f.).
PubMed: Population genetic structure of the medicinal plant Vitex rotundifolia in China: implications for its use and conservation.
PubMed: Estrogen-like activity of volatile components from Vitex rotundifolia L.
PubMed: Evaluation of the estrogenic activity of the constituents in the fruits of Vitex rotundifolia L. for the potential treatment of premenstrual syndrome.
PubMed: Association between chemical and genetic variation of Vitex rotundifolia populations from different locations in China: its implication for quality control of medicinal plants.
PubMed: Identification of methyl chloride-emitting plants and atmospheric measurements on a subtropical island.
PubMed: Anti-nociceptive and anti-hyperprolactinemia activities of Fructus Viticis and its effective fractions and chemical constituents.
PubMed: Phenolic compounds and flavonoids as plant growth regulators from fruit and leaf of Vitex rotundifolia.
PubMed: G2-M arrest and antimitotic activity mediated by casticin, a flavonoid isolated from Viticis Fructus (Vitex rotundifolia Linne fil.).
PubMed: Effects of luteolin on the inhibition of proliferation and induction of apoptosis in human myeloid leukaemia cells.
PubMed: New diterpenes and norditerpenes from the fruits of Vitex rotundifolia.
PubMed: Rotundifuran, a labdane type diterpene from Vitex rotundifolia, induces apoptosis in human myeloid leukaemia cells.
PubMed: Phenylnaphthalene compounds from the subterranean part of Vitex rotundifolia and their antibacterial activity against methicillin-resistant Staphylococcus aureus.
PubMed: Ten new labdane-type diterpenes from the fruit of Vitex rotundifolia.
PubMed: Polymethoxyflavonoids from Vitex rotundifolia inhibit proliferation by inducing apoptosis in human myeloid leukemia cells.
PubMed: Effect of Vitex rotundifolia on immediate-type allergic reaction.
PubMed: Diterpenes from the fruits of Vitex rotundifolia.
PubMed: Vitexicarpin, a flavonoid from the fruits of Vitex rotundifolia, inhibits mouse lymphocyte proliferation and growth of cell lines in vitro.
PubMed: Pharmacologically active components of viticis fructus (Vitex rotundifolia). II. The components having analgesic effects.
PubMed: Rotundial, a new natural mosquito repellent from the leaves of Vitex rotundifolia.
PubMed: Isolation of an aldose reductase inhibitor from the fruits of Vitex rotundifolia Part 2 in the series "Studies on the inhibitory effects of medicinal plant constituents on cataract formation".
PubMed: Studies on the constituents of Vitex rotundifolia L. fil.
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