|
Category:cosmetic, flavor and fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Food Chemicals Codex Listed: | No |
| Soluble in: |
| | water |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
| |
| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
| |
| Pictogram | |
| |
| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
|
Not determined
|
| Dermal Toxicity: |
|
Not determined
|
| Inhalation Toxicity: |
|
Not determined
|
Safety in Use Information:
Safety References:
| EPA ACToR:Toxicology Data |
| EPA Substance Registry Services (SRS):Registry |
| National Institute of Allergy and Infectious Diseases:Data |
| paeonia suffruticosa root water |
References:
| | paeonia suffruticosa root water |
| Pubchem (cas): | 223747-88-4 |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | aqueous solution of the steam distillates obtained from the roots of the chinese peony, paeonia suffruticosa, ranunculaceae | | chinese | peony root water (paeonia suffruticosa) | | tree | peony root water (paeonia suffruticosa) | | | peony root water (paeonia suffruticosa) |
Articles:
| PubMed:Paeonol exerts an anticancer effect on human colorectal cancer cells through inhibition of PGE₂ synthesis and COX-2 expression. |
| PubMed:Revealing metabolomic variations in Cortex Moutan from different root parts using HPLC-MS method. |
| PubMed:The effects of the standardized herbal formula PM014 on pulmonary inflammation and airway responsiveness in a murine model of cockroach allergen-induced asthma. |
| PubMed:Paeonol reverses paclitaxel resistance in human breast cancer cells by regulating the expression of transgelin 2. |
| PubMed:Isolation of antifungal compound from Paeonia suffruticosa and its antifungal mechanism. |
| PubMed:Effects of the root bark of Paeonia suffruticosa on mitochondria-mediated neuroprotection in an MPTP-induced model of Parkinson's disease. |
| PubMed:Anticomplement monoterpenoid glucosides from the root bark of Paeonia suffruticosa. |
| PubMed:Cortex Moutan Induces Bladder Cancer Cell Death via Apoptosis and Retards Tumor Growth in Mouse Bladders. |
| PubMed:New monoterpene glycosides from the root cortex of Paeonia suffruticosa and their potential anti-inflammatory activity. |
| PubMed:Anti-Helicobacter pylori and antiulcerogenic activities of the root cortex of Paeonia suffruticosa. |
| PubMed:Root bark extracts of Juncus effusus and Paeonia suffruticosa protect salivary gland acinar cells from apoptotic cell death induced by cis-platinum (II) diammine dichloride. |
| PubMed:Hypoglycemic and antioxidant activities of paeonol and its beneficial effect on diabetic encephalopathy in streptozotocin-induced diabetic rats. |
| PubMed:Endoplasmic reticulum stress-induced resistance to doxorubicin is reversed by paeonol treatment in human hepatocellular carcinoma cells. |
| PubMed:Wound-healing plants from TCM: in vitro investigations on selected TCM plants and their influence on human dermal fibroblasts and keratinocytes. |
| PubMed:trans-Caffeic acid stearyl ester from Paeonia suffruticosa inhibits melanin synthesis by cAMP-mediating down-regulation of α-melanocyte-stimulating hormone-stimulated melanogenesis signaling pathway in B16 cells. |
| PubMed:Chronic supplementation of paeonol combined with danshensu for the improvement of vascular reactivity in the cerebral basilar artery of diabetic rats. |
| PubMed:Moutan Cortex Radicis inhibits inflammatory changes of gene expression in lipopolysaccharide-stimulated gingival fibroblasts. |
| PubMed:Ethanol extract of paeonia suffruticosa Andrews (PSE) induced AGS human gastric cancer cell apoptosis via fas-dependent apoptosis and MDM2-p53 pathways. |
| PubMed:Suffruyabiosides A and B, two new monoterpene diglycosides from moutan cortex. |
| PubMed:Influence of co-administered danshensu on pharmacokinetic fate and tissue distribution of paeonol in rats. |
| PubMed:Platelet anti-aggregatory and blood anti-coagulant effects of compounds isolated from Paeonia lactiflora and Paeonia suffruticosa. |
| PubMed:Vascular dilation by paeonol--a mechanism study. |
| PubMed:Inhibitory effects of Paeonia suffruticosa on allergic reactions by inhibiting the NF-kappaB/I kappaB-alpha signaling pathway and phosphorylation of ERK in an animal model and human mast cells. |
| PubMed:Antitumor effect of extracts from moutan cortex on DLD-1 human colon cancer cells in vitro. |
| PubMed:The genome-wide expression profile of Paeonia suffruticosa-treated cisplatin-stimulated HEK 293 cells. |
| PubMed:Tyrosinase inhibitors isolated from the roots of Paeonia suffruticosa. |
| PubMed:A pyrrole derivative from Paeonia suffruticosa. |
| PubMed:Paeonol attenuates neurotoxicity and ameliorates cognitive impairment induced by d-galactose in ICR mice. |
| PubMed:Screening of bioactive compounds from moutan cortex and their anti-inflammatory activities in rat synoviocytes. |
| PubMed:Amendment with peony root bark improves the biocontrol efficacy of Trichoderma harzianum against Rhizoctonia solani. |
| PubMed:Traditional Chinese medicine for atopic eczema: PentaHerbs formula suppresses inflammatory mediators release from mast cells. |
| PubMed:Pharmacological investigations of the anti-diabetic effect of Cortex Moutan and its active component paeonol. |
| PubMed:A new monoterpene glycoside and antibacterial monoterpene glycosides from Paeonia suffruticosa. |
| PubMed:Characterization of compounds in the Chinese herbal drug Mu-Dan-Pi by liquid chromatography coupled to electrospray ionization mass spectrometry. |
| PubMed:Acaricidal activities of paeonol and benzoic acid from Paeonia suffruticosa root bark and monoterpenoids against Tyrophagus putrescentiae (Acari: Acaridae). |
| PubMed:Paeonol reduced cerebral infarction involving the superoxide anion and microglia activation in ischemia-reperfusion injured rats. |
| PubMed:Determination of three bioactive constituents in moutan cortex by capillary electrophoresis with electrochemical detection. |
| PubMed:Vasodilatory and anti-inflammatory effects of the 1,2,3,4,6-penta-O-galloyl-beta-D-glucose (PGG) via a nitric oxide-cGMP pathway. |
| PubMed:[A new paeoniflorin derivative isolated from the root bark ethanol extract of Paeonia suffruticosa]. |
| PubMed:Acaricidal activity of Paeonia suffruticosa root bark-derived compounds against Dermatophagoides farinae and Dermatophagoides pteronyssinus (Acari: Pyroglyphidae). |
| PubMed:Protective constituents against sepsis in mice from the root cortex of Paeonia suffruticosa. |
| PubMed:Repellency of aromatic medicinal plant extracts and a steam distillate to Aedes aegypti. |
| PubMed:Penta-O-galloyl-beta-D-glucose inhibits phorbol myristate acetate-induced interleukin-8 [correction of intereukin-8] gene expression in human monocytic U937 cells through its inactivation of nuclear factor-kappaB. |
| PubMed:[Experiment on extraction, sulfonate of paeonol and its antibiotic effect on plant pathogen]. |
| PubMed:Inhibition of inducible nitric oxide synthase and cyclooxygenase-2 activity by 1,2,3,4,6-penta-O-galloyl-beta-D-glucose in murine macrophage cells. |
| PubMed:Insecticides in Chinese medicinal plants: survey leading to jacaranone, a neurotoxicant and glutathione-reactive quinol. |
| PubMed:Inhibitory effects of the root cortex of Paeonia suffruticosa on interleukin-8 and macrophage chemoattractant protein-1 secretions in U937 cells. |
| PubMed:1,2,3,4,6-Penta-O-galloyl-beta-D-glucose protects rat neuronal cells (Neuro 2A) from hydrogen peroxide-mediated cell death via the induction of heme oxygenase-1. |
| PubMed:In vitro anti-proliferative effect of 1,2,3,4,6-penta-O-galloyl-beta-D-glucose on human hepatocellular carcinoma cell line, SK-HEP-1 cells. |
| PubMed:Bioactive constituents of chinese natural medicines. VI. Moutan cortex. (2): structures and radical scavenging effects of suffruticosides A, B, C, D, and E and galloyl-oxypaeoniflorin. |
| PubMed:The inhibition of phenylhydroquinone-induced oxidative DNA cleavage by constituents of Moutan Cortex and Paeoniae Radix. |
| PubMed:Two novel compounds from Paeonia suffructicosa. |
| PubMed:Galloyl-oxypaeoniflorin, suffruticosides A, B, C, and D, five new antioxidative glycosides, and suffruticoside E, A paeonol glycoside, from Chinese moutan cortex. |
| PubMed:Pharmacotherapeutic effects of kuei-chih-fu-ling-wan (keishi-bukuryo-gan) on human uterine myomas. |
| PubMed:Protection by tree-peony (Paeonia suffruticosa Andr) of obesity in (SLN x C3H/He) F1 obese mice. |
| PubMed:Effects of a Chinese herbal medicine, keishi-bukuryo-gan, on the gonadal system of rats. |
| PubMed:Biopharmaceutical studies on crude drug preparations. I: Permeation of paeonol in a decoction and dry extract of Paeonia suffruticosa root cortex using an absorption simulator. |
| PubMed:[A new compound, apiopaeonoside, isolated from the root of Paeonia suffruticosa]. |
|