clausena anisata leaf oil
clausena inaequalis var. abyssinica leaf oil
An essential oil is locally distilled from the leaves of a small tropical tree, Clausena Anisata, related to the citrus trees. The tree is cultivated in Indonesia and in East Africa, but it is particularly popular in the Philippines where the essential oil is distilled and used for a local brandy, equivalent to the French anisette. The oil of Clausena Anisata is almost colorless or pale yellow and its odor is very similar to that of star anise oil.
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Name: clausena anisata hook. f. leaf oil
CAS Number: 91771-51-6 
ECHA EC Number: 294-943-7
Category: information only not used for fragrances or flavors
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Physical Properties:
Appearance: pale yellow clear liquid (est)
Food Chemicals Codex Listed: No
Soluble in:
Insoluble in:
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Organoleptic Properties:
Odor Type: licorice
Odor Strength: medium
 anisic  anise  
Odor Description:
at 100.00 %. 
anisic star anise
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Cosmetic Information:
None found
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 None found
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Safety Information:
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: information only not used for fragrances or flavors
Recommendation for clausena anisata leaf oil usage levels up to:
 not for fragrance use.
Recommendation for clausena anisata leaf oil flavor usage levels up to:
 not for flavor use.
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Safety References:
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
National Institute of Allergy and Infectious Diseases: Data
 clausena anisata hook. f. leaf oil
Chemidplus: 0091771516
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 clausena anisata hook. f. leaf oil
Pubchem (sid): 135315287
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Other Information:
Export Tariff Code: 3301.29.6000
 Typical G.C.
Wikipedia: View
FAO: Clausena anisata
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Potential Blenders and core components note
None Found
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 clausena anisata
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 clausena inaequalis var. abyssinica leaf oil
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PubMed: Cytotoxicity and modes of action of five Cameroonian medicinal plants against multi-factorial drug resistance of tumor cells.
PubMed: Ethnoveterinary medicinal plants used by the Maale and Ari ethnic communities in southern Ethiopia.
PubMed: Isolation of seselin from Clausena anisata (Rutaceae) leaves and its effects on the feeding and development of Lucilia cuprina larvae may explain its use in ethnoveterinary medicine.
PubMed: Efficacy and toxicity of thirteen plant leaf acetone extracts used in ethnoveterinary medicine in South Africa on egg hatching and larval development of Haemonchus contortus.
PubMed: Chemical constituents from stem bark and roots of Clausena anisata.
PubMed: Some southern African plant species used to treat helminth infections in ethnoveterinary medicine have excellent antifungal activities.
PubMed: Assessment of long-term storage on antimicrobial and cyclooxygenase-inhibitory properties of South African medicinal plants.
PubMed: Extracts of four plant species used traditionally to treat myiasis influence pupation rate, pupal mass and adult blowfly emergence of Lucilia cuprina and Chrysomya marginalis (Diptera: Calliphoridae).
PubMed: Evaluation of plant species used traditionally to treat myiasis for activity on the survival and development of Lucilia cuprina and Chrysomya marginalis (Diptera: Calliphoridae).
PubMed: Antioxidant and acetylcholinesterase-inhibitory properties of long-term stored medicinal plants.
PubMed: Antiplasmodial and analgesic activities of Clausena anisata.
PubMed: Isolation and identification of antibacterial compound from the leaves of Cassia auriculata.
PubMed: Evaluation of Clausena anisata essential oil from Cameroon for controlling food spoilage fungi and its potential use as an antiradical agent.
PubMed: Ethnobotanical study of anthelmintic and other medicinal plants traditionally used in Loitoktok district of Kenya.
PubMed: Profile of heavy metals in some medicinal plants from Ghana commonly used as components of herbal formulations.
PubMed: Gamma-lactone carbazoles from Clausena anisata.
PubMed: Ethnobotanical study of medicinal plants used by people in Zegie Peninsula, Northwestern Ethiopia.
PubMed: Antifungal activity of some Tanzanian plants used traditionally for the treatment of fungal infections.
PubMed: Plants used to treat epilepsy by Tanzanian traditional healers.
PubMed: Comparative in vitro effects of AZT and extracts of Ocimum gratissimum, Ficus polita, Clausena anisata, Alchornea cordifolia, and Elaeophorbia drupifera against HIV-1 and HIV-2 infections.
PubMed: Hypoglycaemic effect of Clausena anisata (Willd) Hook methanolic root extract in rats.
PubMed: New carbazole alkaloids from Clausena anisata with antitumor promoting activity.
PubMed: Screening of Zulu medicinal plants for angiotensin converting enzyme (ACE) inhibitors.
PubMed: Clausenol and clausenine--two carbazole alkaloids from Clausena anisata.
PubMed: New biogenetically-significant constituents of Clausena anisata and Murraya koenigii.
PubMed: Estragole: an acute toxic principle from the volatile oil of the leaves of Clausena anisata.
PubMed: Constituents of the Essential Oil of Clausena anisata Leaves.
PubMed: The mutagenicities of seven coumarin derivatives and a furan derivative (nimbolide) isolated from three medicinal plants.
PubMed: Structure-activity relationship in the toxicity of some naturally occurring coumarins-chalepin, imperatorin and oxypeucedanine.
PubMed: [Constituents of Clausena anisata (Willd.) Oliv. (Rutaceae). I. Coumarins from the root bark (author's transl)].
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